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Luca Gattinoni

leibniz institute for immunotherapy
H指数:71
被引数:2.5万

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A modular synthetic promoter toolkit for programmable gene control in activated and chronically stimulated T cells

用于激活和慢性刺激T细胞中可编程基因控制的模块化合成启动子工具包

Nature Communications
IF15.7
2026-09-160
OAAI
Giuliano Bonfá; Giovanna Martino; Assunta Sellitto; Juan Luis Blazquez-Roman; Fabiana Tedeschi; Antonio Rinaldi; Caio Raony Farina Silveira; Francesca Piro; Fabio Caliendo; Loris Melchiorri; Daniela Perna; Rita Tarnai; Christoph Heuser-Loy; Fabio Mastrogiovanni; Timea Vadász; Freddie Starkey; Evangelos Nikolados; Filippo Menolascina; Luca Gattinoni; Velia Siciliano
Distinct in vivo dynamics of donor-derived stem cell memory CAR T cells post-allogeneic HSCT relapse

异基因HSCT复发后供者来源的干细胞记忆CAR T细胞在体内的不同动态

Cell
IF42.5
2026-04-300
OAAI
Luca Gattinoni; Gabriele Inchingolo; Dennis C. Harrer; Alberto Susana; Simone Puccio; Dragana Slavkovic-Lukic; Danielle A. Natrakul; Nicholas Strieder; Christoph Heuser-Loy; Jeremy G. Baldwin; Jessica Fioravanti; Yun Ji; Sanjivan Gautam; Chiara Suriano; Azucena Martín-Santos; Roland C. Schelker; Nisha Patel; Jennifer Mann; Stephanie Goff; Lekha Mikkilineni
Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory

幼稚样记忆T细胞的代谢静息状态先于并维持抗原特异性T细胞记忆

Nature Immunology
IF27.6
2026-02-240
OAAI
Sina Frischholz; Ev-Marie Schuster; Myriam Grotz; Christine Schülein; Julia Benz; Katharina Kocher; Lucia Klotz; Szilard Varga; Theresa Hiltner; Rayya Alsalameh; Jan Esse; Johannes Träger; Jürgen Held; Frederik Graw; Jürgen Pahle; Bernd Spriewald; Luca Gattinoni; Veit R. Buchholz; Felix Drost; Benjamin Schubert; Simon Rothenfußer; Dirk H. Busch; Christian Bogdan; Kilian Schober
NaCl enhances CD8+ T cell effector functions in cancer immunotherapy
NATURE IMMUNOLOGY
IF27.6
2024-08-282
PRE
Scirgolea, Caterina; Sottile, Rosa; De Luca, Marco; Susana, Alberto; Carnevale, Silvia; Puccio, Simone; Ferrari, Valentina; Lise, Veronica; Contarini, Giorgia; Scarpa, Alice; Scamardella, Eloise; Feno, Simona; Camisaschi, Chiara; De Simone, Gabriele; Basso, Gianluca; Giuliano, Desiree; Mazza, Emilia Maria Cristina; Gattinoni, Luca; Roychoudhuri, Rahul; Voulaz, Emanuele; Di Mitri, Diletta; Simonelli, Matteo; Losurdo, Agnese; Pozzi, Davide; Tsui, Carlson; Kallies, Axel; Timo, Sara; Martano, Giuseppe; Barberis, Elettra; Manfredi, Marcello; Rescigno, Maria; Jaillon, Sebastien; Lugli, Enrico
LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness
NATURE COMMUNICATIONS
IF15.7
2024-08-271
OAAI
Pallavicini, Isabella; Frasconi, Teresa Maria; Catozzi, Carlotta; Ceccacci, Elena; Tiberti, Silvia; Haas, Dorothee; Samson, Jule; Heuser-Loy, Christoph; Lauson, Carina B. Nava; Mangione, Marta; Preto, Elisa; Bigogno, Alberto; Sala, Eleonora; Iannacone, Matteo; Mercurio, Ciro; Gattinoni, Luca; Caruana, Ignazio; Kuka, Mirela; Nezi, Luigi; Minucci, Saverio; Manzo, Teresa
LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling
Signal Transduction and Targeted Therapy
IF52.7
2024-08-090
OAAI
Roland C. Schelker; Jessica Fioravanti; Fabio Mastrogiovanni; Jeremy G. Baldwin; Nisha Rana; Peng Li; Ping Chen; Timea Vadász; Rosanne Spolski; Christoph Heuser-Loy; Dragana Slavkovic-Lukic; Pedro Noronha; Giuseppe Damiano; Laura Raccosta; Daniela Maggioni; Sree Pullugula; Jian-Xin Lin; Jangsuk Oh; Patrick Grandinetti; Mario Lecce; Leo Hesse; Emilia Kocks; Azucena Martín-Santos; Claudia Gebhard; William G. Telford; Yun Ji; Nicholas P. Restifo; Vincenzo Russo; Michael Rehli; Wolfgang Herr; Warren J. Leonard; Luca Gattinoni
An engineered IL-2 partial agonist promotes CD8+ T cell stemness
Nature
IF48.5
2021-09-150
PRE
Fei Mo; Zhiya Yu; Peng Li; Jangsuk Oh; Rosanne Spolski; Liang Zhao; Caleb R. Glassman; Tori N. Yamamoto; Yun Chen; Filip M. Golebiowski; Dalton Hermans; Sonia Majri-Morrison; Lora K. Picton; Wei Liao; Min Ren; Xiaoxuan Zhuang; Suman Mitra; Jian-Xin Lin; Luca Gattinoni; Jonathan D. Powell; Nicholas P. Restifo; K. Christopher Garcia; Warren J. Leonard
BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells

BACH2执行干细胞样CD8 T细胞的转录和表观遗传程序

NATURE IMMUNOLOGY
IF27.6
2021-02-1192
OAAI
Yao, Chen; Lou, Guohua; Sun, Hong-Wei; Zhu, Ziang; Sun, Yi; Chen, Zeyu; Chauss, Daniel; Moseman, E. Ashley; Cheng, Jun; D'Antonio, Marc A.; Shi, Wangke; Shi, Junwei; Kometani, Kohei; Kurosaki, Tomohiro; Wherry, E. John; Afzali, Behdad; Gattinoni, Luca; Zhu, Yuwen; McGavern, Dorian B.; O'Shea, John J.; Schwartzberg, Pamela L.; Wu, Tuoqi
Two subsets of stem-like CD8+memory T cell progenitors with distinct fate commitments in humans
NATURE IMMUNOLOGY
IF27.6
2020-10-12194
OAAI
Galletti, Giovanni; De Simone, Gabriele; Mazza, Emilia M. C.; Puccio, Simone; Mezzanotte, Claudia; Bi, Timothy M.; Davydov, Alexey N.; Metsger, Maria; Scamardella, Eloise; Alvisi, Giorgia; De Paoli, Federica; Zanon, Veronica; Scarpa, Alice; Camisa, Barbara; Colombo, Federico S.; Anselmo, Achille; Peano, Clelia; Polletti, Sara; Mavilio, Domenico; Gattinoni, Luca; Boi, Shannon K.; Youngblood, Benjamin A.; Jones, Rhiannon E.; Baird, Duncan M.; Gostick, Emma; Llewellyn-Lacey, Sian; Ladell, Kristin; Price, David A.; Chudakov, Dmitriy M.; Newell, Evan W.; Casucci, Monica; Lugli, Enrico

研究方向

暂未获取到该数据
N
Nicholas P. Restifo
H 指数:150论文数:890被引数:9.6万
D
Douglas C. Palmer
H 指数:51论文数:198被引数:1.7万
Y
Yun Ji
H 指数:38论文数:81被引数:1.0万
C
Christopher A. Klebanoff
H 指数:56论文数:235被引数:2.4万
Z
Zhiya Yu
H 指数:67论文数:305被引数:2.2万
S
Steven A. Rosenberg
H 指数:219论文数:1,556被引数:19.6万
R
Rahul Roychoudhuri
H 指数:41论文数:187被引数:9,367
P
Pawel Muranski
H 指数:39论文数:181被引数:1.2万
M
Madhusudhanan Sukumar
H 指数:25论文数:72被引数:7,233
C
Claudia Wrzesinski
H 指数:17论文数:44被引数:5,224