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R

Rahul Roychoudhuri

University of Cambridge
H指数:41
被引数:9,413

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Author Correction: Proteasome-guided haem signalling axis contributes to T cell exhaustion

作者更正：蛋白酶体引导的血红素信号轴有助于T细胞耗竭

Nature
IF48.5
2026-09-290
PRE
Yingxi Xu; Yangtao Shangguan; Yu-Ming Chuang; Tzu-Hsuan Chang; Wenbing Liu; Jhan-Jie Peng; Josep Garnica; Leling Xie; Pei-Chun Hsueh; Mei-Chun Lin; Yi-Hao Wang; Karina Lobo Hajdu; Yibo Wu; Maryam Akrami; Chen Wang; Anna Kohl; Alfred Zippelius; Wei Qi; Min Wang; Bugi Ratno Budiarto; Shih-Yu Chen; Zhengtao Xiao; Panagiota Vardaka; Rahul Roychoudhuri; Zhiliang Bai; Rong Fan; Santiago Carmona; Yi-Ru Yu; Christoph Scheiermann; Jianxiang Wang; Ping-Chih Ho
Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species

肿瘤源性抗氧化剂通过剥夺T细胞的活性氧来抑制免疫

Science
IF45.8
2026-09-030
PRE
Alexander J. Wesolowski; Ardon M. Pillay; Panagiota Vardaka; Rabab Nasrallah; Randy Greaves; Housaiyin Li; Iliana Loffreda; Chelsea Jenkin; Andrew M. James; Alica Nübling; Christopher J. Ward; Teresa von Linde; Alberto G. Conti; Sheue-Fen Tzeng; Layla Dahmani; Alexander C. Evans; Sarah K. Whiteside; Yumi Yamashita-Kanemaru; Charlotte J. Imianowski; Jie Yang; Ignacio Moraga Gonzalez; Jack Chapman; Aws Al-Deka; Klaus Okkenhaug; Michael P. Murphy; Bartlomiej Swiatczak; Geoffrey Guittard; Enrico Lugli; Lukas Flatz; Ping-Chih Ho; Robert L. Eil; Rahul Roychoudhuri
Author Correction: Proteasome-guided haem signalling axis contributes to T cell exhaustion

作者更正：蛋白酶体引导的血红素信号轴有助于T细胞耗竭

Nature
IF48.5
2026-05-070
PRE
Yingxi Xu; Yangtao Shangguan; Yu-Ming Chuang; Tzu-Hsuan Chang; Wenbing Liu; Jhan-Jie Peng; Josep Garnica; Leling Xie; Pei-Chun Hsueh; Mei-Chun Lin; Yi-Hao Wang; Karina Lobo Hajdu; Yibo Wu; Maryam Akrami; Chen Wang; Anna Kohl; Alfred Zippelius; Wei Qi; Min Wang; Bugi Ratno Budiarto; Shih-Yu Chen; Zhengtao Xiao; Panagiota Vardaka; Rahul Roychoudhuri; Zhiliang Bai; Rong Fan; Santiago Carmona; Yi-Ru Yu; Christoph Scheiermann; Jianxiang Wang; Ping-Chih Ho
Cortisol-resistant CAR-NK cells overcome steroid-induced immunosuppression in lung cancer

皮质醇耐药的car-nk细胞克服了类固醇诱导的肺癌免疫抑制

Signal Transduction and Targeted Therapy
IF52.7
2026-04-090
OAAI
Soura Chakraborty; Jhuma Pramanik; Gustavo Alviter-Raymundo; Christopher J. Ward; Sanu K. Shaji; Yumi Yamashita-Kanemaru; Fatma Abo Zakaib Ali; Debasis Banik; Ziwei Zhang; Clara Veiga-Villauriz; Natalie Z. M. Homer; Joanna Simpson; Sofia Laforest; Shanlin Tong; Qiuchen Zhao; James Roy; Muhammad Iqbal; Andrew Conway Morris; Michael A. Chapman; Rahul Roychoudhuri; Hosni Hussein; David Klenerman; Kourosh Saeb-Parsy; Bidesh Mahata
Proteasome-guided haem signalling axis contributes to T cell exhaustion

蛋白酶体引导的血红素信号轴有助于T细胞耗竭

Nature
IF48.5
2026-03-180
PRE
Yingxi Xu; Yangtao Shangguan; Yu-Ming Chuang; Tzu-Hsuan Chang; Wenbing Liu; Jhan-Jie Peng; Josep Garnica; Leling Xie; Pei-Chun Hsueh; Mei-Chun Lin; Yi-Hao Wang; Karina Lobo Hajdu; Yibo Wu; Maryam Akrami; Chen Wang; Anna Kohl; Alfred Zippelius; Wei Qi; Min Wang; Bugi Ratno Budiarto; Shih-Yu Chen; Zhengtao Xiao; Panagiota Vardaka; Rahul Roychoudhuri; Zhiliang Bai; Rong Fan; Santiago Carmona; Yi-Ru Yu; Christoph Scheiermann; Jianxiang Wang; Ping-Chih Ho
Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy

微调BACH2剂量平衡了stemness和效应子功能，以增强抗肿瘤T细胞治疗

Nature Immunology
IF27.6
2026-01-160
OAAI
Alberto G. Conti; Alexander C. Evans; Teresa von Linde; Christian Deo T. Deguit; Sarah K. Whiteside; Alexander J. Wesolowski; Charlotte J. Imianowski; Yumi Yamashita-Kanemaru; Layla Dahmani; Jack Chapman; Ardon M. Pillay; Aws Al-Deka; Randy Greaves; Oliver Burton; Panagiota Vardaka; Shienny Sampurno; Iván Pérez-Núñez; Nicole Y. L. Saw; Jie Yang; Andrew J. M. Howden; Klaus Okkenhaug; Suman Mitra; Bartlomiej Swiatczak; Ian A. Parish; Rahul Roychoudhuri
NaCl enhances CD8+ T cell effector functions in cancer immunotherapy
NATURE IMMUNOLOGY
IF27.6
2024-08-282
PRE
Scirgolea, Caterina; Sottile, Rosa; De Luca, Marco; Susana, Alberto; Carnevale, Silvia; Puccio, Simone; Ferrari, Valentina; Lise, Veronica; Contarini, Giorgia; Scarpa, Alice; Scamardella, Eloise; Feno, Simona; Camisaschi, Chiara; De Simone, Gabriele; Basso, Gianluca; Giuliano, Desiree; Mazza, Emilia Maria Cristina; Gattinoni, Luca; Roychoudhuri, Rahul; Voulaz, Emanuele; Di Mitri, Diletta; Simonelli, Matteo; Losurdo, Agnese; Pozzi, Davide; Tsui, Carlson; Kallies, Axel; Timo, Sara; Martano, Giuseppe; Barberis, Elettra; Manfredi, Marcello; Rescigno, Maria; Jaillon, Sebastien; Lugli, Enrico
Cross-talk between ILC2 and Gata3high Tregs locally constrains adaptive type 2 immunity
SCIENCE IMMUNOLOGY
IF16.3
2024-07-190
OA
Stockis, Julie; Yip, Thomas; Moreno-Vicente, Julia; Burton, Oliver; Samarakoon, Youhani; Schuijs, Martijn J.; Raghunathan, Shwetha; Garcia, Celine; Luo, Weike; Whiteside, Sarah K.; Png, Shaun; Simpson, Charlotte; Monk, Stela; Sawle, Ashley; Yin, Kelvin; Barbieri, Johanna; Papadopoulos, Panagiotis; Wong, Hannah; Rodewald, Hans-Reimer; Vyse, Timothy; McKenzie, Andrew N. J.; Cragg, Mark S.; Hoare, Matthew; Withers, David R.; Fehling, Hans Joerg; Roychoudhuri, Rahul; Liston, Adrian; Halim, Timotheus Y. F.
Intratumoral antigen signaling traps CD8+ T cells to confine exhaustion to the tumor site
SCIENCE IMMUNOLOGY
IF16.3
2024-05-243
OAAI
Takahashi, Munetomo; So, Tsz Y.; Chamberlain-Evans, Vitalina; Hughes, Robert; Yam-Puc, Juan Carlos; Kania, Katarzyna; Ruhle, Michelle; Mann, Tiffeney; Schuijs, Martijn J.; Coupland, Paul; Naisbitt, Dean; Halim, Timotheus Y. F.; Lyons, Paul A.; Lio, Pietro; Roychoudhuri, Rahul; Okkenhaug, Klaus; Adams, David J.; Smith, Ken G. C.; Jodrell, Duncan I.; Chapman, Michael A.; Thaventhiran, James E. D.
Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion
SCIENCE IMMUNOLOGY
IF16.3
2023-12-158
OAAI
Whiteside, Sarah K.; Grant, Francis M.; Alvisi, Giorgia; Clarke, James; Tang, Leqi; Imianowski, Charlotte J.; Zhang, Baojie; Evans, Alexander C.; Wesolowski, Alexander J.; Conti, Alberto G.; Yang, Jie; Lauder, Sarah N.; Clement, Mathew; Humphreys, Ian R.; Dooley, James; Burton, Oliver; Liston, Adrian; Alloisio, Marco; Voulaz, Emanuele; Langhorne, Jean; Okkenhaug, Klaus; Lugli, Enrico; Roychoudhuri, Rahul
Multimodal single-cell profiling of intrahepatic cholangiocarcinoma defines hyperactivated Tregs as a potential therapeutic target

肝内胆管癌的多模式单细胞分析将超活化的treg定义为潜在的治疗靶标

JOURNAL OF HEPATOLOGY
IF33
2022-11-0150
OAAI
Alvisi, Giorgia; Termanini, Alberto; Soldani, Cristiana; Portale, Federica; Carriero, Roberta; Pilipow, Karolina; Costa, Guido; Polidoro, Michela; Franceschini, Barbara; Malenica, Ines; Puccio, Simone; Lise, Veronica; Galletti, Giovanni; Zanon, Veronica; Colombo, Federico Simone; De Simone, Gabriele; Tufano, Michele; Aghemo, Alessio; Di Tommaso, Luca; Peano, Clelia; Cibella, Javier; Iannacone, Matteo; Roychoudhuri, Rahul; Manzo, Teresa; Donadon, Matteo; Torzilli, Guido; Kunderfranco, Paolo; Di Mitri, Diletta; Lugli, Enrico; Lleo, Ana
BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2022-09-3010
OAAI
Imianowski, Charlotte J.; Whiteside, Sarah K.; Lozano, Teresa; Evans, Alexander C.; Benson, Jayme D.; Courreges, Christina J. F.; Sadiyah, Firas; Lau, Colleen M.; Zandhuis, Nordin D.; Grant, Francis M.; Schuijs, Martijn J.; Vardaka, Panagiota; Kuo, Paula; Soilleux, Elizabeth J.; Yang, Jie; Sun, Joseph C.; Kurosaki, Tomohiro; Okkenhaug, Klaus; Halim, Timotheus Y. F.; Roychoudhuri, Rahul
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein
Science Immunology
IF16.3
2022-01-010
OA
Silvia Gaggero; Jonathan Martínez‐Fábregas; Adeline Cozzani; Paul K. Fyfe; Malo Leprohon; Jie Yang; F. Emil Thomasen; Hauke Winkelmann; Romain Magnez; Alberto G. Conti; Stephan Wilmes; Elizabeth Pöhler; Manuel van Gijsel‐Bonnello; Xavier Thuru; Bruno Quesnel; Fabrice Soncin; Jacob Piehler; Kresten Lindorff‐Larsen; Rahul Roychoudhuri; Ignacio Moraga; Suman Mitra

研究方向

暂未获取到该数据
N
Nicholas P. Restifo
H 指数:150论文数:890被引数:9.6万
K
Klaus Okkenhaug
H 指数:66论文数:187被引数:2.1万
L
Luca Gattinoni
H 指数:71论文数:231被引数:2.5万
C
Christopher A. Klebanoff
H 指数:56论文数:235被引数:2.4万
D
Douglas C. Palmer
H 指数:51论文数:198被引数:1.7万
R
Robert Eil
H 指数:20论文数:110被引数:5,025
Z
Zhiya Yu
H 指数:67论文数:305被引数:2.2万
D
David Clever
H 指数:18论文数:75被引数:3,628
M
Madhusudhanan Sukumar
H 指数:25论文数:72被引数:7,259
Y
Yun Ji
H 指数:38论文数:81被引数:1.1万