未登录 Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy 肿瘤和基质区室中的坏死性凋亡决定了对免疫原性细胞死亡为基础的免疫治疗的反应性 Fernando, Winnie; Clucas, Jarama; Rizzo, Alberto; Singer, Ramsay; Goode, Emily; Tiu, Crescens; Layzell, Scott; Konecnik, Joshua; Wilson, Rebecca; John, Sidonie Wicky; Jouny, Samuel; Guppy, Naomi; Boulat, Victoire; Mannion, Jonathan; Goicoechea, Maria; Tan, Shaun; Lawson, Sam; Starling, Chris; Elshtein, Gabrielle; Ravindran, Nivedita; Montgomery, Anna B.; Andres-Ejarque, Rosa; Allen, Mark; Lumbard, Steven; Wallberg, Fredrik; Betteridge, Kai; Scrimgeour, Ross; Robertson, David; Ward, George; Sims, Martin; Smyth, Tomoko; Samson, Andre L.; Murphy, James M.; Ivankovic, Daniela Kolarevic; Arwert, Esther N.; Calado, Dinis P.; Grigoriadis, Anita; Smalley, Matthew J.; Melcher, Alan; Haider, Syed; Lawrence, Toby; Roxanis, Ioannis; Tutt, Andrew N. J.; Tenev, Tencho; Meier, Pascal 分享 收藏
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Enhanced bacterial cancer therapy delivering therapeutic RNA interference of c-Myc Williams, Jason S.; Higgins, Adam T.; Stott, Katie J.; Thomas, Carly; Farrell, Lydia; Bonnet, Cleo S.; Peneva, Severina; Derrick, Anna V.; Hay, Trevor; Wang, Tianqi; Morgan, Claire; Dwyer, Sarah; D'Ambrogio, Joshua; Hogan, Catherine; Smalley, Matthew J.; Parry, Lee; Dyson, Paul 分享 收藏
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A live tissue platform allows dynamic measurement of neovascularization and prediction of clinical response in human breast cancer samples, ex vivo Smalley, M.; Alam, N.; Murmu, N.; Somashekhar, S.; Ulaganathan, B.; Thayakumar, A.; Maciejko, L.; Ganesh, J.; Lawson, M.; Gertje, H.; Shanthappa, B. U.; Goldman, A. 分享 收藏
Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells Tornillo, Giusy; Knowlson, Catherine; Kendrick, Howard; Cooke, Joe; Mirza, Hasan; Aurrekoetxea-Rodriguez, Iskander; Vivanco, Maria D. M.; Buckley, Niamh E.; Grigoriadis, Anita; Smalley, Matthew J. 分享 收藏
Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth Pearson, Helen B.; Li, Jason; Meniel, Valerie S.; Fennell, Christina M.; Waring, Paul; Montgomery, Karen G.; Rebello, Richard J.; Macpherson, Arthi A.; Koushyar, Sarah; Furic, Luc; Cullinane, Carleen; Clarkson, Richard W.; Smalley, Matthew J.; Simpson, Kaylene J.; Phesse, Toby J.; Shepherd, Peter R.; Humbert, Patrick O.; Sansom, Owen J.; Phillips, Wayne A. 分享 收藏
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PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression Chiang, Kelly; Zielinska, Agnieszka E.; Shaaban, Abeer M.; Sanchez-Bailon, Maria Pilar; Jarrold, James; Clarke, Thomas L.; Zhang, Jingxian; Francis, Adele; Jones, Louise J.; Smith, Sally; Barbash, Olena; Guccione, Ernesto; Farnie, Gillian; Smalley, Matthew J.; Davies, Clare C. 分享 收藏
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The receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis Soady, Kelly J.; Tornillo, Giusy; Kendrick, Howard; Meniel, Valerie; Olijnyk-Dallis, Daria; Morris, Joanna S.; Stein, Torsten; Gusterson, Barry A.; Isacke, Clare M.; Smalley, Matthew J. 分享 收藏
Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids Jarde, Thierry; Lloyd-Lewis, Bethan; Thomas, Mairian; Kendrick, Howard; Melchor, Lorenzo; Bougaret, Lauriane; Watson, Peter D.; Ewan, Kenneth; Smalley, Matthew J.; Dale, Trevor C. 分享 收藏
Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression Estrada, Marta F.; Rebelo, Sofia P.; Davies, Emma J.; Pinto, Marta T.; Pereira, Hugo; Santo, Vitor E.; Smalley, Matthew J.; Barry, Simon T.; Gualda, Emilio J.; Alves, Paula M.; Anderson, Elizabeth; Brito, Catarina 分享 收藏
Runx2 contributes to the regenerative potential of the mammary epithelium Ferrari, Nicola; Riggio, Alessandra I.; Mason, Susan; McDonald, Laura; King, Ayala; Higgins, Theresa; Rosewell, Ian; Neil, James C.; Smalley, Matthew J.; Sansom, Owen J.; Morris, Joanna; Cameron, Ewan R.; Blyth, Karen 分享 收藏
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Whole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours Brca2和Trp53-deficient小鼠乳腺肿瘤的全外显子DNA序列分析 Francis, Jeffrey C.; Melchor, Lorenzo; Campbell, James; Kendrick, Howard; Wei, Wenbin; Armisen-Garrido, Javier; Assiotis, Ioannis; Chen, Lina; Kozarewa, Iwanka; Fenwick, Kerry; Swain, Amanda; Smalley, Matthew J.; Lord, Christopher J.; Ashworth, Alan 分享 收藏