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J

Jean-Christophe Marine

VIB
H指数:95
被引数:4.4万

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AMP-activated protein kinase-driven lipid droplet dynamics govern melanoma sensitivity to polyunsaturated fatty acid and iron-induced ferroptosis

AMP激活蛋白激酶驱动的脂滴动力学调控黑素瘤对多不饱和脂肪酸和铁诱导的铁死亡敏感性

Nature Communications
IF15.7
2025-12-170
OAAI
Sahar Motamedi; Nina Ravoet; Jonas Dehairs; Frank Vanderhoydonc; Abril Escamilla-Ayala; Malgorzata A. Sliwinska; Shuncong Wang; Jakub Idkowiak; Stefaan Soenen; Patrizia Agostinis; Jean-Christophe Marine; Johannes V. Swinnen
Single-cell mapping of alternative splicing linked to checkpoint immunotherapy response

单细胞图谱分析：与免疫检查点疗法反应相关的选择性剪接

NUCLEIC ACIDS RESEARCH
IF13.1
2025-11-260
PRE
Xiong, Jieyi; Bricard, Orian; Arijs, Ingrid; Demeulemeester, Jonas; Gu, Chen; Thienpont, Bernard; Daaboul, Danie; Bassez, Ayse; Bechter, Oliver; Pozniak, Joanna; Vos, Hanne; Nevelsteen, Ines; Torfs, Sofie; Santos, Sara Aibar; Lan, Qing; Hou, Yong; Van oudenhove, Lore; Boons, Gitta; Qian, Junbin; Aerts, Stein; Smeets, Ann; Marine, Jean-Christophe; Lambrechts, Diether
Decoding tumor heterogeneity: A spatially informed pan-cancer analysis of the tumor microenvironment

解码肿瘤异质性：一项关于肿瘤微环境的基于空间信息的泛癌分析

Cell Reports Medicine
IF10.6
2025-10-140
OAAI
Francesca Lodi; Sam Vanmassenhove; Duojiao Chen; Bram Boeckx; Lucas Ferreira Maciel; Frederik Peeters; Elena Donders; Heesoo Song; Luuk Harbers; Joanna Poźniak; Liselore Loverix; Yiduo Zhou; Michel Bila; Ayse Bassez; Sarah Cappuyns; Tom Venken; Siel Olbrecht; Amelie Franken; Pierre Van Mol; Rogier Schepers; Thomas van Brussel; Gino Philips; Hanne Vos; Machteld Keupers; Frederik De Smet; Sabine Tejpar; Oliver Bechter; Gabriele Bergers; Ann Smeets; Paul Clement; Els Wauters; Jeroen Dekervel; Toon Van Gorp; Junbin Qian; Jean-Christophe Marine; Diether Lambrechts
BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states

BDH2驱动的溶酶体到线粒体的铁转移塑造了黑色素瘤细胞状态的铁死亡易感性。

Nature Metabolism
IF20.8
2025-09-160
OAAI
Francesca Rizzollo; Abril Escamilla-Ayala; Nicola Fattorelli; Natalia Barbara Lysiak; Sanket More; Pablo Hernández Varas; Lucia Barazzuol; Chris Van den Haute; Joris Van Asselberghs; David Nittner; Jonathan Coene; Vivek Venkataramani; Bernhard Michalke; Christine Gaillet; Tatiana Cañeque; Irwin Davidson; Steven H. L. Verhelst; Peter Vangheluwe; Tito Calì; Jean-Christophe Marine; Raphaël Rodriguez; Julie Bonnereau; Patrizia Agostinis
Specific modulation of 28S_Um2402 rRNA 2′-O-ribose methylation as a novel epitranscriptomic marker of ZEB1-induced epithelial-mesenchymal transition in different mammary cell contexts

28S_Um2402 rRNA 2 ′-O-核糖甲基化的特异性调节作为不同乳腺细胞环境中ZEB1-induced上皮-间充质转化的新型表观遗传标记

NAR CANCER
IF3.2
2025-01-280
OAAI
Morin, Chloe; Paraqindes, Hermes; Van Long, Flora Nguyen; Isaac, Caroline; Thomas, Emilie; Pedri, Dennis; Pulido-Vicuna, Carlos Ariel; Morel, Anne-Pierre; Marchand, Virginie; Motorin, Yuri; Carrere, Marjorie; Auclair, Jessie; Attignon, Valery; Pommier, Roxane M.; Ruiz, Emmanuelle; Bourdelais, Fleur; Catez, Frederic; Durand, Sebastien; Ferrari, Anthony; Viari, Alain; Marine, Jean-Christophe; Puisieux, Alain; Diaz, Jean-Jacques; Moyret-Lalle, Caroline; Marcel, Virginie
Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis

分泌的Apoe重新连接黑色素瘤细胞状态对铁死亡的脆弱性

SCIENCE ADVANCES
IF12.5
2024-10-181
OAAI
More, Sanket; Bonnereau, Julie; Wouters, David; Spotbeen, Xander; Karras, Panagiotis; Rizzollo, Francesca; Killian, Theo; Venken, Tom; Naulaerts, Stefan; Vervoort, Ellen; Ganne, Maarten; Nittner, David; Verhoeven, Jelle; Bechter, Oliver; Bosisio, Francesca; Lambrechts, Diether; Sifrim, Alejandro; Stockwell, Brent R.; Swinnen, Johannes V.; Marine, Jean Christophe; Agostinis, Patrizia
Cancer drug-tolerant persister cells: from biological questions to clinical opportunities

癌症药物耐受性持久细胞: 从生物学问题到临床机会

NATURE REVIEWS CANCER
IF66.8
2024-09-020
PRE
Russo, Mariangela; Chen, Mengnuo; Mariella, Elisa; Peng, Haoning; Rehman, Sumaiyah K.; Sancho, Elena; Sogari, Alberto; Toh, Tzen S.; Balaban, Nathalie Q.; Batlle, Eduard; Bernards, Rene; Garnett, Mathew J.; Hangauer, Matthew; Leucci, Eleonora; Marine, Jean-Christophe; O'Brien, Catherine A.; Oren, Yaara; Patton, E. Elizabeth; Robert, Caroline; Rosenberg, Susan M.; Shen, Shensi; Bardelli, Alberto
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma

缬氨酸氨酰tRNA合成酶促进黑色素瘤的治疗抵抗

NATURE CELL BIOLOGY
IF19.1
2024-06-072
OAAI
El-Hachem, Najla; Leclercq, Marine; Susaeta Ruiz, Miguel; Vanleyssem, Raphael; Shostak, Kateryna; Koerner, Pierre-Rene; Capron, Coralie; Martin-Morales, Lorena; Roncarati, Patrick; Lavergne, Arnaud; Blomme, Arnaud; Turchetto, Silvia; Goffin, Eric; Thandapani, Palaniraja; Tarassov, Ivan; Nguyen, Laurent; Pirotte, Bernard; Chariot, Alain; Marine, Jean-Christophe; Herfs, Michael; Rapino, Francesca; Agami, Reuven; Close, Pierre
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity (vol 8, pg 861, 2016)

p53诱导含有NEAT1 lncRNA的副斑的形成，调节复制应激反应和化学敏感性 (第8卷，861页，2016)

NATURE MEDICINE
IF50
2024-02-080
OA
Adriaens, Carmen; Standaert, Laura; Barra, Jasmine; Latil, Mathilde; Verfaillie, Annelien; Kalev, Peter; Boeckx, Bram; Wijnhoven, Paul. W. G.; Radaelli, Enrico; Vermi, William; Leucci, Eleonora; Lapouge, Gaelle; Beck, Benjamin; van den Oord, Joost; Nakagawa, Shinichi; Hirose, Tetsuro; Sablina, Anna. A.; Lambrechts, Diether; Aerts, Stein; Blanpain, Cedric; Marine, Jean-Christophe
Cancer Evolution: A Multifaceted Affair

癌症进化: 一个多方面的事件

CANCER DISCOVERY
IF33.3
2023-12-0610
OAAI
Ciriello, Giovanni; Magnani, Luca; Aitken, Sarah J.; Akkari, Leila; Behjati, Sam; Hanahan, Douglas; Landau, Dan A.; Lopez-Bigas, Nuria; Lupianez, Dario G.; Marine, Jean-Christophe; Martin-Villalba, Ana; Natoli, Gioacchino; Obenauf, Anna C.; Oricchio, Elisa; Scaffidi, Paola; Sottoriva, Andrea; Swarbrick, Alexander; Tonon, Giovanni; Vanharanta, Sakari; Zuber, Johannes
Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma

肿瘤内皮细胞自噬是黑色素瘤中关键的血管免疫检查点

EMBO MOLECULAR MEDICINE
IF8.3
2023-11-277
OAAI
Verhoeven, Jelle; Jacobs, Kathryn A.; Rizzollo, Francesca; Lodi, Francesca; Hua, Yichao; Pozniak, Joanna; Srinivasan, Adhithya Narayanan; Houbaert, Diede; Shankar, Gautam; More, Sanket; Schaaf, Marco B.; Lakic, Nikolina Dubroja; Ganne, Maarten; Lamote, Jochen; Van Weyenbergh, Johan; Boon, Louis; Bechter, Oliver; Bosisio, Francesca; Uchiyama, Yasuo; Bertrand, Mathieu J. M.; Marine, Jean Christophe; Lambrechts, Diether; Bergers, Gabriele; Agrawal, Madhur; Agostinis, Patrizia
Melanoma-intrinsic NR2F6 activity regulates antitumor immunity

黑素瘤-内在NR2F6活性调节抗肿瘤免疫

SCIENCE ADVANCES
IF12.5
2023-07-075
OAAI
Kim, Hyungsoo; Feng, Yongmei; Murad, Rabi; Pozniak, Joanna; Pelz, Carl; Chen, Yeqing; Dalal, Bhavik; Sears, Rosalie; Sergienko, Eduard; Jackson, Michael; Ruppin, Eytan; Herlyn, Meenhard; Harris, Curtis; Marine, Jean-Christophe; Klepsch, Victoria; Baier, Gottfried; Ronai, Ze'ev A.
Apoptotic cell death in disease-Current understanding of the NCCD 2023

疾病中的凋亡细胞死亡-对NCCD 2023的当前理解

CELL DEATH AND DIFFERENTIATION
IF15.4
2023-04-26143
OAAI
Vitale, Ilio; Pietrocola, Federico; Guilbaud, Emma; Aaronson, Stuart A.; Abrams, John M.; Adam, Dieter; Agostini, Massimiliano; Agostinis, Patrizia; Alnemri, Emad S.; Altucci, Lucia; Amelio, Ivano; Andrews, David W.; Aqeilan, Rami, I; Arama, Eli; Baehrecke, Eric H.; Balachandran, Siddharth; Bano, Daniele; Barlev, Nickolai A.; Bartek, Jiri; Bazan, Nicolas G.; Becker, Christoph; Bernassola, Francesca; Bertrand, Mathieu J. M.; Bianchi, Marco E.; Blagosklonny, Mikhail V.; Blander, J. Magarian; Blandino, Giovanni; Blomgren, Klas; Borner, Christoph; Bortner, Carl D.; Bove, Pierluigi; Boya, Patricia; Brenner, Catherine; Broz, Petr; Brunner, Thomas; Damgaard, Rune Busk; Calin, George A.; Campanella, Michelangelo; Candi, Eleonora; Carbone, Michele; Carmona-Gutierrez, Didac; Cecconi, Francesco; Chan, Francis K-M; Chen, Guo-Qiang; Chen, Quan; Chen, Youhai H.; Cheng, Emily H.; Chipuk, Jerry E.; Cidlowski, John A.; Ciechanover, Aaron; Ciliberto, Gennaro; Conrad, Marcus; Cubillos-Ruiz, Juan R.; Czabotar, Peter E.; D'Angiolella, Vincenzo; Daugaard, Mads; Dawson, Ted M.; Dawson, Valina L.; De Maria, Ruggero; De Strooper, Bart; Debatin, Klaus-Michael; Deberardinis, Ralph J.; Degterev, Alexei; Del Sal, Giannino; Deshmukh, Mohanish; Di Virgilio, Francesco; Diederich, Marc; Dixon, Scott J.; Dynlacht, Brian D.; El-Deiry, Wafik S.; Elrod, John W.; Engeland, Kurt; Fimia, Gian Maria; Galassi, Claudia; Ganini, Carlo; Garcia-Saez, Ana J.; Garg, Abhishek D.; Garrido, Carmen; Gavathiotis, Evripidis; Gerlic, Motti; Ghosh, Sourav; Green, Douglas R.; Greene, Lloyd A.; Gronemeyer, Hinrich; Haecker, Georg; Hajnoczky, Gyorgy; Hardwick, J. Marie; Haupt, Ygal; He, Sudan; Heery, David M.; Hengartner, Michael O.; Hetz, Claudio; Hildeman, David A.; Ichijo, Hidenori; Inoue, Satoshi; Jaeaettelae, Marja; Janic, Ana; Joseph, Bertrand; Jost, Philipp J.; Kanneganti, Thirumala-Devi; Karin, Michael; Kashkar, Hamid; Kaufmann, Thomas; Kelly, Gemma L.; Kepp, Oliver; Kimchi, Adi; Kitsis, Richard N.; Klionsky, Daniel J.; Kluck, Ruth; Krysko, Dmitri, V; Kulms, Dagmar; Kumar, Sharad; Lavandero, Sergio; Lavrik, Inna N.; Lemasters, John J.; Liccardi, Gianmaria; Linkermann, Andreas; Lipton, Stuart A.; Lockshin, Richard A.; Lopez-Otin, Carlos; Luedde, Tom; MacFarlane, Marion; Madeo, Frank; Malorni, Walter; Manic, Gwenola; Mantovani, Roberto; Marchi, Saverio; Marine, Jean-Christophe; Martin, Seamus J.; Martinou, Jean-Claude; Mastroberardino, Pier G.; Medema, Jan Paul; Mehlen, Patrick; Meier, Pascal; Melino, Gerry; Melino, Sonia; Miao, Edward A.; Moll, Ute M.; Munoz-Pinedo, Cristina; Murphy, Daniel J.; Niklison-Chirou, Maria Victoria; Novelli, Flavia; Nunez, Gabriel; Oberst, Andrew; Ofengeim, Dimitry; Opferman, Joseph T.; Oren, Moshe; Pagano, Michele; Panaretakis, Theocharis; Pasparakis, Manolis; Penninger, Josef M.; Pentimalli, Francesca; Pereira, David M.; Pervaiz, Shazib; Peter, Marcus E.; Pinton, Paolo; Porta, Giovanni; Prehn, Jochen H. M.; Puthalakath, Hamsa; Rabinovich, Gabriel A.; Rajalingam, Krishnaraj; Ravichandran, Kodi S.; Rehm, Markus; Ricci, Jean-Ehrland; Rizzuto, Rosario; Robinson, Nirmal; Rodrigues, Cecilia M. P.; Rotblat, Barak; Rothlin, Carla, V; Rubinsztein, David C.; Rudel, Thomas; Rufini, Alessandro; Ryan, Kevin M.; Sarosiek, Kristopher A.; Sawa, Akira; Sayan, Emre; Schroder, Kate; Scorrano, Luca; Sesti, Federico; Shao, Feng; Shi, Yufang; Sica, Giuseppe S.; Silke, John; Simon, Hans-Uwe; Sistigu, Antonella; Stephanou, Anastasis; Stockwell, Brent R.; Strapazzon, Flavie; Strasser, Andreas; Sun, Liming; Sun, Erwei; Sun, Qiang; Szabadkai, Gyorgy; Tait, Stephen W. G.; Tang, Daolin; Tavernarakis, Nektarios; Troy, Carol M.; Turk, Boris; Urbano, Nicoletta; Vandenabeele, Peter; Vanden Berghe, Tom; Vander Heiden, Matthew G.; Vanderluit, Jacqueline L.; Verkhratsky, Alexei; Villunger, Andreas; von Karstedt, Silvia; Voss, Anne K.; Vousden, Karen H.; Vucic, Domagoj; Vuri, Daniela; Wagner, Erwin F.; Walczak, Henning; Wallach, David; Wang, Ruoning; Wang, Ying; Weber, Achim; Wood, Will; Yamazaki, Takahiro; Yang, Huang-Tian; Zakeri, Zahra; Zawacka-Pankau, Joanna E.; Zhang, Lin; Zhang, Haibing; Zhivotovsky, Boris; Zhou, Wenzhao; Piacentini, Mauro; Kroemer, Guido; Galluzzi, Lorenzo
Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy

膜脂质多不饱和的药理学诱导使黑色素瘤对ROS诱导剂敏感，并克服了对靶向治疗的获得性抗性

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2023-04-196
OAAI
Talebi, Ali; de Laat, Vincent; Spotbeen, Xander; Dehairs, Jonas; Rambow, Florian; Rogiers, Aljosja; Vanderhoydonc, Frank; Rizotto, Lara; Planque, Melanie; Doglioni, Ginevra; Motamedi, Sahar; Nittner, David; Roskams, Tania; Agostinis, Patrizia; Bechter, Oliver; Boecxstaens, Veerle; Garmyn, Marjan; O'Farrell, Marie; Wagman, Alan; Kemble, George; Leucci, Eleonora; Fendt, Sarah-Maria; Marine, Jean-Christophe; Swinnen, Johannes V. V.
Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma

HSD11B1对糖皮质激素的激活限制了T细胞驱动的干扰素信号传导和对黑色素瘤PD-1阻断的反应

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2023-04-0711
OAAI
Melo, Luiza Martins Nascentes; Herrera-Rios, Dayana; Hinze, Daniel; Loeffek, Stefanie; Oezel, Irem; Turiello, Roberta; Klein, Juliane; Leonardelli, Sonia; Westedt, Isa-Vanessa; Al-Matary, Yahya; Egea-Rodriguez, Sara; Brenzel, Alexandra; Bau, Maja; Sucker, Antje; Hadaschik, Eva; Wirsdoerfer, Florian; Hanenberg, Helmut; Uhlenbrock, Niklas; Rauh, Daniel; Pozniak, Joanna; Rambow, Florian; Marine, Jean-Christophe; Effern, Maike; Glodde, Nicole; Schadendorf, Dirk; Jablonska, Jadwiga; Hoelzel, Michael; Helfrich, Iris

研究方向

暂未获取到该数据
F
Florian Rambow
H 指数:36论文数:190被引数:1.3万
E
Eleonora Leucci
H 指数:32论文数:162被引数:4,904
A
Aart G. Jochemsen
H 指数:38论文数:108被引数:4,905
D
Diether Lambrechts
H 指数:122论文数:1,318被引数:6.9万
D
David Nittner
H 指数:18论文数:63被引数:3,471
E
Enrico Radaelli
H 指数:50论文数:396被引数:9,766
O
Oliver Bechter
H 指数:37论文数:291被引数:1.1万
C
Cédric Blanpain
H 指数:89论文数:247被引数:3.9万
P
Pier Giuseppe Pelicci
H 指数:125论文数:942被引数:6.2万
P
Patrizia Agostinis
H 指数:99论文数:472被引数:6.2万