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Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in luminal A breast cancer 肿瘤昼夜节律强度影响腔a型乳腺癌的转移潜力并预测患者预后 Li, Shi-Yang; Hammarlund, Jan A.; Wu, Gang; Lian, Jia-Wen; Howell, Sacha J.; Clarke, Robert B.; Adamson, Antony D.; Goncalves, Catia F.; Hogenesch, John B.; Anafi, Ron C.; Meng, Qing-Jun 分享 收藏
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research 超越想象: 乳腺生物学和乳腺癌研究的最新突破和下一个挑战 van Amerongen, Renee; Bentires-Alj, Mohamed; van Boxtel, Antonius L. L.; Clarke, Robert B. B.; Fre, Silvia; Suarez, Eva Gonzalez; Iggo, Richard; Jechlinger, Martin; Jonkers, Jos; Mikkola, Marja L.; Koledova, Zuzana Sumbalova; Sorlie, Therese; Vivanco, Maria dM. 分享 收藏
A preclinical platform of breast cancer PDX and derived cellular models as a tool for pharmacological screening and functional studies 乳腺癌PDX的临床前平台和衍生的细胞模型作为药物筛选和功能研究的工具 Nicolle, Delphine; Gorce, Aurore; Tavernier, Marie; Marangoni, Elisabetta; Decaudin, Didier; Ginestier, Christophe; Charafe-Jaufret, Emmanuelle; Passildas, Judith; Robin, Nina; Clarke, Robert; Corcuff, Erwan; Joachim, Anais; Malissen, Bernard; Zarubica, Ana; Luche, Herve; Judde, Jean-Gabriel; Deas, Olivier 分享 收藏
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RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells RAC1B功能对于乳腺癌干细胞的维持和乳腺肿瘤细胞的化学抗性至关重要 Chen, Fuhui; Gurler, Sevim B.; Novo, David; Selli, Cigdem; Alferez, Denis G.; Eroglu, Secil; Pavlou, Kyriaki; Zhang, Jingwei; Sims, Andrew H.; Humphreys, Neil E.; Adamson, Antony; Campbell, Andrew; Sansom, Owen J.; Tournier, Cathy; Clarke, Robert B.; Brennan, Keith; Streuli, Charles H.; Ucar, Ahmet 分享 收藏
High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer (September, 10.1038/s41467-022-32828-6, 2022) 高p16表达和杂合RB1丢失是ER乳腺癌中CDK4/6抑制剂抗性的生物标志物 (9月，10.1038/s41467-022-32828-6，2022) Palafox, Marta; Monserrat, Laia; Bellet, Meritxell; Villacampa, Guillermo; Gonzalez-Perez, Abel; Oliveira, Mafalda; Braso-Maristany, Fara; Ibrahimi, Nusaibah; Kannan, Srinivasaraghavan; Mina, Leonardo; Herrera-Abreu, Maria Teresa; Odena, Andreu; Sanchez-Guixe, Monica; Capelan, Marta; Azaro, Analia; Bruna, Alejandra; Rodriguez, Olga; Guzman, Marta; Grueso, Judit; Viaplana, Cristina; Hernandez, Javier; Su, Faye; Lin, Kui; Clarke, Robert B.; Caldas, Carlos; Arribas, Joaquin; Michiels, Stefan; Garcia-Sanz, Alicia; Turner, Nicholas C.; Prat, Aleix; Nuciforo, Paolo; Dienstmann, Rodrigo; Verma, Chandra S.; Lopez-Bigas, Nuria; Scaltriti, Maurizio; Arnedos, Monica; Saura, Cristina; Serra, Violeta 分享 收藏
High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer 高p16表达和杂合RB1缺失是ER乳腺癌中CDK4/6抑制剂耐药的生物标志物 Palafox, Marta; Monserrat, Laia; Bellet, Meritxell; Villacampa, Guillermo; Gonzalez-Perez, Abel; Oliveira, Mafalda; Braso-Maristany, Fara; Ibrahimi, Nusaibah; Kannan, Srinivasaraghavan; Mina, Leonardo; Herrera-Abreu, Maria Teresa; Odena, Andreu; Sanchez-Guixe, Monica; Capelan, Marta; Azaro, Analia; Bruna, Alejandra; Rodriguez, Olga; Guzman, Marta; Grueso, Judit; Viaplana, Cristina; Hernandez, Javier; Su, Faye; Lin, Kui; Clarke, Robert B.; Caldas, Carlos; Arribas, Joaquin; Michiels, Stefan; Garcia-Sanz, Alicia; Turner, Nicholas C.; Prat, Aleix; Nuciforo, Paolo; Dienstmann, Rodrigo; Verma, Chandra S.; Lopez-Bigas, Nuria; Scaltriti, Maurizio; Arnedos, Monica; Saura, Cristina; Serra, Violeta 分享 收藏
Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification 用于鉴定同源重组缺陷肿瘤和患者分层的RAD51测试的临床前体内验证 Pellegrino, Benedetta; Herencia-Ropero, Andrea; Llop-Guevara, Alba; Pedretti, Flaminia; Moles-Fernandez, Alejandro; Viaplana, Cristina; Villacampa, Guillermo; Guzman, Marta; Rodriguez, Olga; Grueso, Judit; Jimenez, Jose; Arenas, Enrique J.; Degasperi, Andrea; Dias, Joao M. L.; Forment, Josep, V; O'Connor, Mark J.; Deas, Olivier; Cairo, Stefano; Zhou, Yinghui; Musolino, Antonino; Caldas, Carlos; Nik-Zainal, Serena; Clarke, Robert B.; Nuciforo, Paolo; Diez, Orland; Serres-Creixams, Xavier; Peg, Vicente; Espinosa-Bravo, Martin; Macarulla, Teresa; Oaknin, Ana; Mateo, Joaquin; Arribas, Joaquin; Dienstmann, Rodrigo; Bellet, Meritxell; Oliveira, Mafalda; Saura, Cristina; Gutierrez-Enriquez, Sara; Balmana, Judith; Serra, Violeta 分享 收藏
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Results from the breast cancer - anti progestin prevention study 1 (BC-APPS1) trial - a novel approach in breast cancer prevention Howell, Sacha; Greenhalgh, Alice; Pedley, Robert; Alghamdi, Suad; Caruso, Amanda; Ansari, Mujtaba; Moreira, Tiago; Astlet, Sue; Maxwell, Anthony; Lim, Yit; Brookes, Hayley; Idries, Faiza; Howell, Anthony; Evans, D. Gareth; Sherratt, Michael; Gilmore, Andrew; Harkness, Elaine; Khaled, Walid; Twigger, Alecia-Jane; Roberts, Matt; Clarke, Robert; Simoes, Bruno 分享 收藏
Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs 循环内体中受体酪氨酸激酶之间的相互引发协调细胞信号输出 Smith, Michael P.; Ferguson, Harriet R.; Ferguson, Jennifer; Zindy, Egor; Kowalczyk, Katarzyna M.; Kedward, Thomas; Bates, Christian; Parsons, Joseph; Watson, Joanne; Chandler, Sarah; Fullwood, Paul; Warwood, Stacey; Knight, David; Clarke, Robert B.; Francavilla, Chiara 分享 收藏
FAK inhibition alone or in combination with adjuvant therapies reduces cancer stem cell activity Timbrell, Simon; Aglan, Hosam; Cramer, Angela; Foden, Phil; Weaver, David; Pachter, Jonathan; Kilgallon, Aoife; Clarke, Robert B.; Farnie, Gillian; Bundred, Nigel J. 分享 收藏
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