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S

Saar Gill

University of Pennsylvania
H指数:59
被引数:1.7万

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Single-day non-activated IL-18-armed CAR T-cells establish a durable, stem-like state with enhanced persistence

单日未激活的IL-18武装CAR T细胞建立一种持久的、干细胞样状态并增强持久性

Blood
IF23.1
2026-04-200
PRE
Joseph S. Durgin; Shin Seo; Shadab Kazmi; Bakir Valentic; Chloe Leff; Martina Markovska; Xiaoling Jin; Feng Shen; Abdulla Berjis; Nandana Mukherjee; Ashwin Sannecy; Gabriela Plesa; Khatuna Gabunia; John Scholler; Saar I. Gill; Roddy S. O’Connor; Carl H. June; Saba Ghassemi
Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer

泛血液学癌症对嵌合抗原受体 (CAR) T细胞治疗反应的预测生物标志物

Nature Biomedical Engineering
IF26.6
2026-03-090
PRE
Gregory M. Chen; Ankita Jain; David T. Gering; Javier Satulovsky; Sarbani Datta; Peng Lai; Jayashree Karar; Vanessa E. Gonzalez; Kathleen Alexander; Anne Chew; Julie K. Jadlowsky; Marco Ruella; Luca Paruzzo; Kevin R. Amses; Andrew J. Rech; Edward A. Stadtmauer; Noelle V. Frey; Elizabeth O. Hexner; David L. Porter; Adam D. Cohen; Saar I. Gill; Alfred L. Garfall; Stephen J. Schuster; Kelvin C. Mo; Samantha I. Liang; Marko Spasic; Bruce L. Levine; Don L. Siegel; Angel Ramírez-Fernández; Christopher R. Cabanski; EnJun Yang; Crystal L. Mackall; Frederic D. Bushman; Zinaida Good; E. John Wherry; Carl H. June; Joseph A. Fraietta
Preclinical evaluation of antigen-specific B-cell depletion for phospholipase A2 receptor membranous nephropathy with chimeric autoantibody receptor T-cells.

抗原特异性B细胞清除在磷脂酶A2受体膜性肾病中的临床前评估，采用嵌合自体抗体受体T细胞。

Kidney International
IF12.6
2025-10-310
PRE
Burcin Altun; Gexin Zhao; Baomei Wang; Xuming Mao; Silvio Manfredo-Vieira; Elinor Willis; Enrico Radaelli; Emma E. Goodman; Alina C. Boesteanu; Saar I. Gill; Darshil R. Patel; Steven Wong; Ebony Cottman-Thomas; Jonathan J. Hogan; Aimee S. Payne
Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models (vol 16, 706, 2025)

嵌合抗原受体巨噬细胞（CAR-M）在预临床模型中使HER2+实体瘤对PD1阻断敏感（卷16，706，2025）

NATURE COMMUNICATIONS
IF15.7
2025-03-192
OA
Pierini, Stefano; Gabbasov, Rashid; Oliveira-Nunes, Maria Cecilia; Qureshi, Rehman; Worth, Alison; Huang, Shuo; Nagar, Karan; Griffin, Crystal; Lian, Lurong; Yashiro-Ohtani, Yumi; Ross, Kayleigh; Sloas, Christopher; Ball, Michael; Schott, Benjamin; Sonawane, Poonam; Cornell, Linara; Blumenthal, Daniel; Chhum, Sotheavy; Minutolo, Nicholas; Ciccaglione, Kerri; Shaw, Lauren; Zentner, Isaac; Levitsky, Hyam; Shestova, Olga; Gill, Saar; Varghese, Bindu; Cushing, Daniel; DeLong, Sabrina Ceeraz; Abramson, Sascha; Condamine, Thomas; Klichinsky, Michael
Evolving racial/ethnic disparities in AML survival in the novel therapy era

新型疗法时代急性髓系白血病（AML）生存率的种族/族裔差异演变

BLOOD ADVANCES
IF7.1
2025-01-311
PRE
Wang, Xin; Gimotty, Phyllis A.; Matthews, Andrew H.; Mamtani, Ronac; Luger, Selina M.; Hexner, Elizabeth O.; V. Babushok, Daria; Mccurdy, Shannon R.; V. Frey, Noelle; Bruno, Ximena Jordan; Gill, Saar; Martin, Mary Ellen; Paralkar, Vikram R.; Maillard, Ivan; Porter, David L.; Loren, Alison W.; Perl, Alexander E.; Pratz, Keith W.; Getz, Kelly D.; Lai, Catherine
Prolonged Neurologic Symptoms Following Immune Effector Cell-Associated Neurotoxicity Syndrome in Patients With Large B-cell Lymphoma Treated With Chimeric Antigen Receptor-Modified T Cell Therapy

经嵌合抗原受体修饰的T细胞治疗的大b细胞淋巴瘤患者免疫效应细胞相关神经毒性综合征后神经系统症状延长

TRANSPLANTATION AND CELLULAR THERAPY
IF4.4
2025-01-010
PRE
Maillie, Luke; Nasta, Sunita D.; Svoboda, Jakub; Barta, Stefan K.; Chong, Elise A.; Garfall, Alfred L.; Gill, Saar I.; Porter, David L.; Schuster, Stephen J.; Catania, Christopher; Frey, Noelle, V; Landsburg, Daniel J.
Cytokine-mediated CAR T therapy resistance in AML

细胞因子介导的AML car-t治疗耐药

NATURE MEDICINE
IF50
2024-09-272
PRE
Bhagwat, Anand S.; Torres, Leonel; Shestova, Olga; Shestov, Maksim; Mellors, Patrick W.; Fisher, Han R.; Farooki, Saamia N.; Frost, Benjamin F.; Loken, Michael R.; Gaymon, Avery L.; Frazee, Diane; Rogal, Walter; Frey, Noelle; Hexner, Elizabeth O.; Luger, Selina M.; Loren, Alison W.; Martin, Mary Ellen; Mccurdy, Shannon R.; Perl, Alexander E.; Stadtmauer, Edward A.; Brogdon, Jennifer L.; Fraietta, Joseph A.; Hwang, Wei-Ting; Siegel, Don L.; Plesa, Gabriela; Aplenc, Richard; Porter, David L.; June, Carl H.; Gill, Saar I.
ACT To Sustain: Adoptive Cell Therapy To Sustain Access to Non-Commercialized Genetically Modified fi ed Cell Therapies
TRANSPLANTATION AND CELLULAR THERAPY
IF4.4
2024-08-012
PRE
Gardner, Rebecca A.; White, Claire; Elsallab, Magdi; Farnia, Stephanie; Fraint, Ellen; Grilley, Bambi; Bateman-House, Alison; Grupp, Stephan A.; Kenderian, Saad; Locke, Frederick L.; Nikiforow, Sarah; Oluwole, Olalekan O.; Rouce, Rayne H.; Spiegel, Jay; Shah, Nirali N.; Sharma, Akshay; Komanduri, Krishna; Gill, Saar
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome

靶向小胶质细胞中tgf β 活化激酶-1活化可降低CAR T免疫效应细胞相关神经毒性综合征

NATURE CANCER
IF28.5
2024-05-133
PRE
Vinnakota, Janaki Manoja; Biavasco, Francesca; Schwabenland, Marius; Chhatbar, Chintan; Adams, Rachael; Erny, Daniel; Duquesne, Sandra; El Khawanky, Nadia; Schmidt, Dominik; Fetsch, Viktor; Zaehringer, Alexander; Salie, Henrike; Athanassopoulos, Dimitrios; Braun, Lukas; Javorniczky, Nora; Ho, Jenny; Kierdorf, Katrin; Marks, Reinhard; Waesch, Ralph; Simonetta, Federico; Andrieux, Geoffroy; Pfeifer, Dietmar; Monaco, Gianni; Capitini, Christian; Fry, Terry; Blank, Thomas; Blazar, Bruce; Wagner, Eva; Theobald, Matthias; Sommer, Clemens; Stelljes, Matthias; Reicherts, Christian; Jeibmann, Astrid; Schittenhelm, Jens; Monoranu, Camelia-Maria; Rosenwald, Andreas; Kortuem, Martin; Rasche, Leo; Einsele, Hermann; Meyer, Philipp; Brumberg, Joachim; Voelkl, Simon; Mackensen, Andreas; Coras, Roland; von Bergwelt-Baildon, Michael; Albert, Nathalie; Bartos, Laura; Brendel, Matthias; Holzgreve, Adrien; Mack, Matthias; Boerries, Melanie; Mackall, Crystal; Duyster, Justus; Henneke, Philipp; Priller, Josef; Koehler, Natalie; Struebing, Felix; Bengsch, Bertram; Ruella, Marco; Subklewe, Marion; von Baumgarten, Louisa; Gill, Saar; Prinz, Marco; Zeiser, Robert
Translational insights from a phase 1, first-in-human (FIH) clinical trial of the anti-HER2 CAR macrophage CT-0508 in participants with HER2 positive metastatic breast cancer and other HER2 overexpressing solid tumors
CANCER RESEARCH
IF16.6
2024-05-021
PRE
Abdou, Yara; Mortimer, Joanne; Pohlmann, Paula; Johnson, Melissa; Maziarz, Richard; Specht, Jennifer M.; Dees, Claire; Ueno, Naoto; Yuan, Yuan; Angelos, Mathew; Gill, Saar; Shestova, Olga; Serody, Jonathon; Priceman, Saul; Qureshi, Rehman; Sonawane, Poonam; Pierini, Stefano; Oliveira-Nunes, Maria Cecilia; Cushing, Daniel; Klichinsky, Michael; Condamine, Thomas; Swaby, Ramona; Reiss, Kim
Hypomethylating agents are associated with high rates of hematologic toxicity in patients with secondary myeloid neoplasms developing after acquired aplastic anemia
HAEMATOLOGICA
IF7.9
2024-04-181
OAAI
Connor, Matthew P.; Prathapa, Neeharika; Frey, Noelle V.; Gill, Saar I.; Hexner, Elizabeth O.; Bruno, Ximena Jordan; Lai, Catherine E.; Loren, Alison W.; Luger, Selina M.; Matthews, Andrew H.; Mccurdy, Shannon R.; Perl, Alexander E.; Porter, David L.; Zeringue, Arlene; Oved, Joseph H.; Olson, Timothy S.; Pratz, Keith W.; Babushok, Daria V.
Preconditioning Frailty Phenotype Influences Survival and Relapse for Older Allogeneic Transplantation Recipients
TRANSPLANTATION AND CELLULAR THERAPY
IF4.4
2024-04-015
OAAI
Sung, Anthony D.; Koll, Thuy; Gier, Shannon H.; Racioppi, Alessandro; White, Griffin; Lew, Meagan; Free, Marcia; Agarwal, Priyal; Bohannon, Lauren M.; Johnson, Ernaya J.; Selvan, Bharathi; Babushok, Daria V.; Frey, Noelle V.; Gill, Saar I.; Hexner, Elizabeth O.; Martin, Maryellen; Perl, Alexander E.; Pratz, Keith W.; Luger, Selina M.; Chao, Nelson J.; Fisher, Alfred L.; Stadtmauer, Edward A.; Porter, David L.; Loren, Alison W.; Bhatt, Vijaya R.; Gimotty, Phyllis A.; Mccurdy, Shannon R.

研究方向

暂未获取到该数据
C
Carl H. June
H 指数:177论文数:1,428被引数:14.4万
M
Marco Ruella
H 指数:48论文数:344被引数:1.3万
N
Noelle V. Frey
H 指数:53论文数:452被引数:2.2万
O
Olga Shestova
H 指数:38论文数:176被引数:9,312
D
David L. Porter
H 指数:61论文数:453被引数:3.3万
M
Michael Klichinsky
H 指数:21论文数:91被引数:6,057
E
Elizabeth O. Hexner
H 指数:56论文数:483被引数:1.4万
A
Alison W. Loren
H 指数:48论文数:363被引数:1.3万
S
Selina M. Luger
H 指数:65论文数:642被引数:2.1万
M
Mary Ellen Martin
H 指数:17论文数:94被引数:2,445