Jennifer P. Morton - Publications, H-index & Citations

Jennifer P. Morton

Cancer Research UK Scotland Institute

77H指数

391论文数

2.5W被引数

收录论文 139

发表时间

Comparative Analysis of Primary and Liver Fibroblasts Reveals MET as a Potent Target in Pancreatic Cancer Metastasis 比较原代和肝成纤维细胞的差异分析揭示了MET作为胰腺癌转移的潜在靶点

Cellular and Molecular Gastroenterology and Hepatology

IF7.4

2026-09-05

OAAI

Rima Singh; Natalie Yousefian; Walker M. Allen; Austin D. Silva; Cecily Anaraki; Alica K. Michels; Sabrina Calderon; Ian M. Loveless; Daniella Rastelli; Ashley George; Mohammed Aldakkak; Oliver G. McDonald; Nikki K. Lytle; Jennifer P. Morton; Reed I. Ayabe; David Imagawa; Zeljka Jutric; Thomas F. Martinez; Nina G. Steele; Christopher J. Halbrook

HSP47 is a potential dual cell target and prognostic factor in pancreatic cancer HSP47是胰腺癌中一个潜在的双细胞靶点和预后因素

Oncogene

IF7.3

2026-06-21

OAAI

George Sharbeen; Estrella Gonzales-Aloy; Janet Youkhana; John Kokkinos; Rosa Mistica C. Ignacio; Joshua A. McCarroll; Aparna S. Raina; Chantal Kopecky; Jie Liu; Amanda Mawson; Andrea Nunez; Cyrille Boyer; Mert Erkan; David Goldstein; Koroush S. Haghighi; Paul Timpson; Sean C. Warren; Kendelle J. Murphy; Anthony J. Gill; Amber L. Johns; Angela Chou; Elvis Pandzic; Sandra Fok; Renee Whan; Val Gebski; Jennifer P. Morton; Minoti Apte; Phoebe A. Phillips

Author Correction: A complex secretory program orchestrated by the inflammasome controls paracrine senescence 作者更正：由炎症小体调控的复杂分泌程序控制旁分泌衰老

Nature Cell Biology

IF19.1

2026-04-28

PREAI

Juan Carlos Acosta; Ana Banito; Torsten Wuestefeld; Athena Georgilis; Peggy Janich; Jennifer P. Morton; Dimitris Athineos; Tae-Won Kang; Felix Lasitschka; Mindaugas Andrulis; Gloria Pascual; Kelly J. Morris; Sadaf Khan; Hong Jin; Gopuraja Dharmalingam; Ambrosius P. Snijders; Thomas Carroll; David Capper; Catrin Pritchard; Gareth J. Inman; Thomas Longerich; Owen J. Sansom; Salvador Aznar Benitah; Lars Zender; Jesús Gil

βIII-tubulin can act as a brake on extrinsic apoptosis in pancreatic cancer βIII-微管蛋白可作为胰腺癌中细胞凋亡的外源性抑制因素

Cell Death & Disease

IF9.6

2026-04-24

OAAI

George Sharbeen; John Kokkinos; Grace Schulstad; Elvis Pandzic; Janet Youkhana; Zerong Ma; Rosa Mistica C. Ignacio; Aparna S. Raina; Shannon Chiang; Cyrille Boyer; Koroush S. Haghighi; Matthew Gunawarman; David Goldstein; Val Gebski; Marina Pajic; Meagan E. Davis; Oliver S. M. Arkell; Chantal Kopecky; Estrella Gonzales-Aloy; Alexander Ishak; Mert Erkan; Jennifer P. Morton; Maria Kavallaris; Peter W. Gunning; Edna C. Hardeman; Amber Johns; Anthony J. Gill; Renee M. Whan; Amanda Mawson; Omali Pitiyarachchi; Joshua A. McCarroll; Phoebe A. Phillips

Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer 剪接体诱导是RAS驱动的衰老和癌症的药物依赖性

Nature Communications

IF15.7

2026-04-15

OAAI

Verena Wagner; Laura Bousset; Mariana Ascensão-Ferreira; Bin Sun; José Efren Barragan Avila; Alexandre Kaizeler; Rita Martins-Silva; Mohammad Rahbari; Mirian Fernández-Vaquero; Scott Haston; Michele Tinti; Joaquim Pombo; Sanjay Khadayate; Susanne Roth; Christian M. Schürch; Juan Pedro Martínez-Barbera; Anat Bahat; Keng Boon Wee; Jennifer P. Morton; Nisar Malek; Andrew J. Innes; Santiago Vernia; Nuno L. Barbosa-Morais; Suchira Gallage; Mathias Heikenwalder; Jesús Gil

Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis (vol. 124, pg. 1069, 2014)p53突变相关的肌球蛋白-X上调促进乳腺癌侵袭和转移（vol. 124, pg. 1069, 2014）

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2025-12-01

PREAI

Arjonen, Antti; Kaukonen, Riina; Mattila, Elina; Rouhi, Pegah; Hognas, Gunilla; Sihto, Harri; Miller, Bryan W.; Morton, Jennifer P.; Bucher, Elmar; Taimen, Pekka; Virtakoivu, Reetta; Cao, Yihai; Sansom, Owen J.; Joensuu, Heikki; Ivaska, Johanna

Engineered cyclic peptide targeting ITGA5 disrupts tumor-stroma interaction to overcome desmoplasia and resistance in pancreatic ductal adenocarcinoma 工程化环肽靶向ITGA5破坏肿瘤-基质相互作用以克服胰腺导管腺癌中的病理性纤维化和耐药性

Acta Pharmaceutica Sinica B

IF14.6

2025-10-24

OAAI

Deby Fajar Mardhian; Kunal P. Pednekar; Ahmed G. Hemdan; Praneeth Reddy Kuninty; Saadia A. Karim; Sabine de Winter; Josbert M. Metselaar; Jennifer P. Morton; Jai Prakash

ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis ER-phagy和蛋白质稳态缺陷促进KRAS介导的致癌作用中胰腺上皮状态的变化

Developmental Cell

IF8.7

2025-08-14

OAAI

Carla Salomó Coll; Marisa Di Monaco; Jocelyn Holkham; Matthew Smith; Morwenna Muir; Philippe Gautier; Hywel Dunn-Davies; Xiaozhong Zheng; Roopesh Krishnankutty; Alain J. Kemp; Katie Winnington-Ingram; Alex von Kriegsheim; Jennifer P. Morton; Natalia Jimenez-Moreno; Damian Mole; Simon Wilkinson

KRASG12D Cells Override Homeostatic Cell Elimination Mechanisms in Adult Pancreas Via Wnt5a and Cell Dormancy KRASG12D细胞通过Wnt5a和细胞休眠机制绕过成年胰腺中的稳态细胞清除机制。

Gastroenterology

IF25.1

2025-04-07

OAAI

Beatriz Salvador-Barbero; Markella Alatsatianos; Jennifer P. Morton; Owen J. Sansom; Catherine Hogan

Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control 通过抑制PI3Kγ和放射治疗诱导巨噬细胞吞噬细胞凋亡小体，可促进胰腺癌的控制

GUT

IF25.8

2025-01-09

PREAI

Russell, Shannon Nicole; Demetriou, Constantinos; Valenzano, Giampiero; Evans, Alice; Go, Simei; Stanly, Tess; Hazini, Ahmet; Willenbrock, Frances; Gordon-Weeks, Alex Nicolas; Mukherjee, Somnath; Tesson, Matthias; Morton, Jennifer P.; O'Neill, Eric; Jones, Keaton Ian

Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas (vol 26, pg 2535, 2019)

CELL DEATH AND DIFFERENTIATION

IF15.4

2024-08-02

OAAI

Liko, Dritan; Mitchell, Louise; Campbell, Kirsteen J.; Ridgway, Rachel A.; Jones, Carolyn; Dudek, Kate; King, Ayala; Bryson, Sheila; Stevenson, David; Blyth, Karen; Strathdee, Douglas; Morton, Jennifer P.; Bird, Thomas G.; Knight, John R. P.; Willis, Anne E.; Sansom, Owen J.

The preclinical gap in pancreatic cancer and radiotherapy

DISEASE MODELS & MECHANISMS

IF3.3

2024-07-09

OAAI

Tesson, Mathias; Morton, Jennifer P.

Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response 暂时分辨的蛋白质组学将nidogen-2鉴定为胰腺癌的共靶标，其调节纤维化和治疗反应

SCIENCE ADVANCES

IF12.5

2024-07-05

OAAI

Pereira, Brooke A.; Ritchie, Shona; Chambers, Cecilia R.; Gordon, Katie A.; Magenau, Astrid; Murphy, Kendelle J.; Nobis, Max; Tyma, Victoria M.; Liew, Ying Fei; Lucas, Morghan C.; Naeini, Marjan M.; Barkauskas, Deborah S.; Chacon-Fajardo, Diego; Howell, Anna E.; Parker, Amelia L.; Warren, Sean C.; Reed, Daniel A.; Lee, Victoria; Metcalf, Xanthe L.; Lee, Young Kyung; O'Regan, Luke P.; Zhu, Jessie; Trpceski, Michael; Fontaine, Angela R. M.; Stoehr, Janett; Rouet, Romain; Lin, Xufeng; Chitty, Jessica L.; Porazinski, Sean; Wu, Sunny Z.; Filipe, Elysse C.; Cadell, Antonia L.; Holliday, Holly; Yang, Jessica; Papanicolaou, Michael; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Vennin, Claire; Yin, Julia; Dew, Alysha B.; Mcmillan, Paul J.; Goldstein, Leonard D.; Deveson, Ira W.; Croucher, David R.; Samuel, Michael S.; Sim, Hao-Wen; Batten, Marcel; Chantrill, Lorraine; Grimmond, Sean M.; Gill, Anthony J.; Samra, Jaswinder; Evans, Thomas R. Jeffry; Sasaki, Takako; Phan, Tri G.; Swarbrick, Alexander; Sansom, Owen J.; Morton, Jennifer P.; Pajic, Marina; Parker, Benjamin L.; Herrmann, David; Cox, Thomas R.; Timpson, Paul

Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer 巨噬细胞-成纤维细胞JAK/STAT依赖性串扰促进胰腺癌肝转移生长

NATURE COMMUNICATIONS

IF15.7

2024-04-27

OAAI

Raymant, Meirion; Astuti, Yuliana; Alvaro-Espinosa, Laura; Green, Daniel; Quaranta, Valeria; Bellomo, Gaia; Glenn, Mark; Chandran-Gorner, Vatshala; Palmer, Daniel H.; Halloran, Christopher; Ghaneh, Paula; Henderson, Neil C.; Morton, Jennifer P.; Valiente, Manuel; Mielgo, Ainhoa; Schmid, Michael C.

Targeting radiation- driven invasion and metastasis in pancreatic cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Mclay, Kathy; Tesson, Mathias; Gilmour, Dion; Morton, Jennifer P.; Birch, Joanna L.

Targeted irradiation in an autochthonous mouse model of pancreatic cancer

DISEASE MODELS & MECHANISMS

IF3.3

2024-03-14

OAAI

Tesson, Mathias; Stevenson, Katrina; Karim, Saadia A.; Nixon, Colin; Chalmers, Anthony J.; Sansom, Owen J.; O'Neill, Eric; Jones, Keaton; Morton, Jennifer P.

Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis (FEB, 10.1038/s43018-024-00731-2, 2024)

NATURE CANCER

IF28.5

2024-03-12

OAAI

Astuti, Yuliana; Raymant, Meirion; Quaranta, Valeria; Clarke, Kim; Abudula, Maidinaimu; Smith, Olivia; Bellomo, Gaia; Chandran-Gorner, Vatshala; Nourse, Craig; Halloran, Christopher; Ghaneh, Paula; Palmer, Daniel; Jones, Robert P.; Campbell, Fiona; Pollard, Jeffrey W.; Morton, Jennifer P.; Mielgo, Ainhoa; Schmid, Michael C.

Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis 胞吞作用重新编程肿瘤微环境促进胰腺癌肝转移

NATURE CANCER

IF28.5

2024-02-14

OAAI

Multiomic modelling of pancreatic IPMN stroma reveals distinct tertiary lymphoid structure distribution: Mapping the transcriptomic landscape via regional bulk, single-cell and subcellular approaches

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Cameron, Andrew J.; Legrini, Assya; Wood, Colin S.; Nourse, Craig; Doncheva, Yoana; Dietrich, Claire Kennedy; Nixon, Colin; Hay, Jennifer; Duthie, Fraser; Herzyk, Pawel; Morton, Jennifer; Jamieson, Nigel B.

KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in colorectal cancer in vivo

NATURE COMMUNICATIONS

IF15.7

2024-01-02

OAAI

Najumudeen, Arafath K.; Fey, Sigrid K.; Millett, Laura M.; Ford, Catriona A.; Gilroy, Kathryn; Gunduz, Nuray; Ridgway, Rachel A.; Anderson, Eve; Strathdee, Douglas; Clark, William; Nixon, Colin; Morton, Jennifer P.; Campbell, Andrew D.; Sansom, Owen J.

研究方向