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Boyi Gan

The University of Texas MD Anderson Cancer Center
H指数:62
被引数:2.9万

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Divergent roles of SPOP and CHD1 in ACSL4 regulation reveal context-dependent vulnerabilities for targeting ferroptosis

泛素连接酶SPOP和染色质重塑因子CHD1在调控ACSL4中的不同作用揭示了靶向铁死亡依赖性的环境依赖性弱点

Nature Communications
IF15.7
2026-06-010
PRE
Chen, Feiyu; Li, Qidong; Gu, Qianlin; Leo, Javier; Liang, Xin; Mehta, Naayaa; Labanca, Estefania; Shepherd, Peter; Mahmud, Iqbal; Wang, Yin; Saenz, Francisco R.; Phillips, Maya M.; Shi, Wei; Meng, Chenling; Zhang, Jie; Frigo, Daniel E.; Lu, Yue; Gan, Boyi; Zhao, Di
In vivo CRISPR activation screen identifies acyl-CoA-binding protein as a driver of bone metastasis

体内CRISPR激活筛选鉴定酰基辅酶A结合蛋白为骨转移的驱动因子

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2025-05-210
PRE
Teng, Hongqi; Hang, Qinglei; Zheng, Caishang; Yan, Yuelong; Liu, Shaomin; Zhao, Yang; Deng, Yalan; Nie, Litong; Wu, Weiche; Sheldon, Marisela; Yu, Zachary; Shi, Wei; Gao, Jianxuan; Meng, Chenling; Martinez, Consuelo; Zhang, Jie; Yao, Fan; Sun, Yutong; Zhao, Di; Gan, Boyi
CHD1 loss reprograms SREBP2-driven cholesterol synthesis to fuel androgen-responsive growth and castration resistance in SPOP-mutated prostate tumors

CHD1缺失重编程SREBP2驱动的胆固醇合成，以支持雄激素应答性生长和去势抵抗在SPOP突变的前列腺肿瘤中。

NATURE CANCER
IF28.5
2025-05-131
PRE
Chen, Feiyu; Li, Haoyan; Wang, Yin; Tang, Ximing; Lin, Kevin; Li, Qidong; Meng, Chenling; Shi, Wei; Leo, Javier; Liang, Xin; Zhang, Jie; Van, Vivien; Mahmud, Iqbal; Wei, Bo; Lorenzi, Philip L.; Raso, Maria G.; Aparicio, Ana; Lu, Yue; Frigo, Daniel E.; Gan, Boyi
Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

镰状细胞病诱导CD8+ T细胞发生染色质内卷和铁死亡，以抑制抗肿瘤免疫。

Immunity
IF26.3
2025-05-120
OA
Zilong Zhao; Benxia Hu; Yalan Deng; Melinda Soeung; Jun Yao; Lanxin Bei; Yaohua Zhang; Pengju Gong; Lisa A. Huang; Zhou Jiang; Jian Gao; Shuang Peng; Tina K. Nguyen; Menuka Karki; Bora Lim; Cassian Yee; Jared K. Burks; Qing Zhang; Li Ma; Jianjun Gao; Nizar M. Tannir; Leng Han; Dihua Yu; Linghua Wang; Michael A. Curran; Maria A. Gubbiotti; Giannicola Genovese; Boyi Gan; Wenbo Li; Pavlos Msaouel; Liuqing Yang; Chunru Lin
Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance

放射疗法促进铜死亡，并与铜死亡诱导剂协同作用以克服肿瘤放射抗性

Cancer Cell
IF44.5
2025-04-100
OA
Guang Lei; Mingchuang Sun; Jun Cheng; Rui Ye; Zhengze Lu; Amber Horbath; David Huo; Shengrong Wu; Anagha Alapati; Sadhna Aggarwal; Zhihao Xu; Chao Mao; Yuelong Yan; Jun Yao; Qidong Li; Xiong Chen; Hyemin Lee; Li Zhuang; Dadi Jiang; Apar Pataer; Jack A. Roth; Nicholas Navin; Albert C. Koong; Mingjian James You; Steven H. Lin; Boyi Gan
Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins

肿瘤细胞通过脂肪酸结合蛋白避免免疫细胞诱导的铁死亡。

MOLECULAR CANCER
IF33.9
2025-02-031
OA
Freitas-Cortez, Maria Angelica; Masrorpour, Fatemeh; Jiang, Hong; Mahmud, Iqbal; Lu, Yue; Huang, Ailing; Duong, Lisa K.; Wang, Qi; Voss, Tiffany A.; Leyton, Claudia S. Kettlun; Wei, Bo; Chan, Wai-Kin; Lin, Kevin; Zhang, Jie; Tsouko, Efrosini; Ganjoo, Shonik; Barsoumian, Hampartsoum B.; Riad, Thomas S.; Hu, Yun; Leuschner, Carola; Puebla-Osorio, Nahum; Wang, Jing; Hu, Jian; Davies, Michael A.; Puduvalli, Vinay K.; Billon, Cyrielle; Burris, Thomas P.; Lorenzi, Philip L.; Gan, Boyi; Welsh, James W.

研究方向

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刘晓光 封面图
刘晓光
H 指数:43论文数:227被引数:1.2万
G
Guang Lei
H 指数:27论文数:66被引数:1.0万
Y
Yilei Zhang
H 指数:36论文数:144被引数:1.3万
C
Chao Mao
H 指数:35论文数:126被引数:8,877
H
Hyemin Lee
H 指数:22论文数:99被引数:7,165
L
Li Zhuang
H 指数:38论文数:150被引数:1.2万
P
Pranavi Koppula
H 指数:17论文数:32被引数:9,999
Y
Yuelong Yan
H 指数:15论文数:40被引数:4,556
K
Kellen Olszewski
H 指数:29论文数:58被引数:6,838
Li Ma 封面图
Li Ma
H 指数:70论文数:428被引数:2.5万