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TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes TSC2在神经祖细胞中的缺失抑制了神经发育基因的mRNA翻译 Martin, Pauline; Szkop, Krzysztof J.; Robert, Francis; Bhattacharyya, Srirupa; Beauchamp, Roberta L.; Brenner, Jacob; Redmond, Nicholas E.; Huang, Sidong; Erdin, Serkan; Larsson, Ola; Ramesh, Vijaya 分享 收藏
Plasticity of the mammalian integrated stress response 哺乳动物整合应激反应的塑性 Chen, Chien-Wen; Papadopoli, David; Szkop, Krzysztof J.; Guan, Bo-Jhih; Alzahrani, Mohammed; Wu, Jing; Jobava, Raul; Asraf, Mais M.; Krokowski, Dawid; Vourekas, Anastasios; Merrick, William C.; Komar, Anton A.; Koromilas, Antonis E.; Gorospe, Myriam; Payea, Matthew J.; Wang, Fangfang; Clayton, Benjamin L. L.; Tesar, Paul J.; Schaffer, Ashleigh; Miron, Alexander; Bederman, Ilya; Jankowsky, Eckhard; Vogel, Christine; Valasek, Leos Shivaya; Dinman, Jonathan D.; Zhang, Youwei; Tirosh, Boaz; Larsson, Ola; Topisirovic, Ivan; Hatzoglou, Maria 分享 收藏
Hypoxia-induced epigenetic changes coordinate transcription start site selection and translational control through remodeling of 5'UTRsHypoxia-induced epigenetic changes coordinate transcription start site selection and translational control through remodeling of 5'UTRs Watt, Kathleen; Dauber, Bianca; Szkop, Krzysztof J.; Lee, Laura; Jovanovic, Predrag; Chen, Shan; Masvidal, Laia; Tandoc, Kristofersson; Palia, Ranveer; Topisirovic, Ivan; Larsson, Ola; Postovit, Lynne-Marie 分享 收藏
Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations Aksoylu, Inci S.; Martin, Pauline; Robert, Francis; Szkop, Krzysztof J.; Redmond, Nicholas E.; Bhattacharyya, Srirupa; Wang, Jennifer; Chen, Shan; Beauchamp, Roberta L.; Nobeli, Irene; Pelletier, Jerry; Larsson, Ola; Ramesh, Vijaya 分享 收藏
Control of protein synthesis through mRNA pseudouridylation by dyskerin dyskerin通过mRNA假尿苷化控制蛋白质合成 Pederiva, Chiara; Trevisan, Davide M.; Peirasmaki, Dimitra; Chen, Shan; Savage, Sharon A.; Larsson, Ola; Ule, Jernej; Baranello, Laura; Agostini, Federico; Farnebo, Marianne 分享 收藏
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A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development Morita, Masahiro; Ler, Lian Wee; Fabian, Marc R.; Siddiqui, Nadeem; Mullin, Michael; Henderson, Valerie C.; Alain, Tommy; Fonseca, Bruno D.; Karashchuk, Galina; Bennett, Christopher F.; Kabuta, Tomohiro; Higashi, Shinji; Larsson, Ola; Topisirovic, Ivan; Smith, Robert J.; Gingras, Anne-Claude; Sonenberg, Nahum 分享 收藏
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Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1 (vol 27, pg 1629, 2008) Vasilcanu, R.; Vasilcanu, D.; Rosengren, L.; Natalishvili, N.; Sehat, B.; Yin, S.; Girnita, A.; Axelson, M.; Girnita, L.; Larsson, O. 分享 收藏
Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR Krokowski, Dawid; Jobava, Raul; Szkop, Krzysztof J.; Chen, Chien-Wen; Fu, Xu; Venus, Sarah; Guan, Bo-Jhih; Wu, Jing; Gao, Zhaofeng; Banaszuk, Wioleta; Tchorzewski, Marek; Mu, Tingwei; Ropelewski, Phil; Merrick, William C.; Mao, Yuanhui; Sevval, Aksoylu Inci; Miranda, Helen; Qian, Shu-Bing; Manifava, Maria; Ktistakis, Nicholas T.; Vourekas, Anastasios; Jankowsky, Eckhard; Topisirovic, Ivan; Larsson, Ola; Hatzoglou, Maria 分享 收藏
MNK2 deficiency potentiates β-cell regeneration via translational regulation Karampelias, Christos; Watt, Kathleen; Mattsson, Charlotte L.; Ruiz, Angel Fernandez; Rezanejad, Habib; Mi, Jiarui; Liu, Xiaojing; Chu, Lianhe; Locasale, Jason W.; Korbutt, Gregory S.; Rovira, Meritxell; Larsson, Ola; Andersson, Olov 分享 收藏
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma Smith, Lorey K.; Parmenter, Tiffany; Kleinschmidt, Margarete; Kusnadi, Eric P.; Kang, Jian; Martin, Claire A.; Lau, Peter; Patel, Riyaben; Lorent, Julie; Papadopoli, David; Trigos, Anna; Ward, Teresa; Rao, Aparna D.; Lelliott, Emily J.; Sheppard, Karen E.; Goode, David; Hicks, Rodney J.; Tiganis, Tony; Simpson, Kaylene J.; Larsson, Ola; Blythe, Benjamin; Cullinane, Carleen; Wickramasinghe, Vihandha O.; Pearson, Richard B.; McArthur, Grant A. 分享 收藏
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Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth (vol 17, pg 1065, 2021) Lee, Bianca J.; Boyer, Jacob A.; Burnett, G. Leslie; Thottumkara, Arun P.; Tibrewal, Nidhi; Wilson, Stacy L.; Hsieh, Tientien; Marquez, Abby; Lorenzana, Edward G.; Evans, James W.; Hulea, Laura; Kiss, Gert; Liu, Hui; Lee, Dong; Larsson, Ola; McLaughlan, Shannon; Topisirovic, Ivan; Wang, Zhengping; Wang, Zhican; Zhao, Yongyuan; Wildes, David; Aggen, James B.; Singh, Mallika; Gill, Adrian L.; Smith, Jacqueline A. M.; Rosen, Neal 分享 收藏
The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer Ghaddar, Nour; Wang, Shuo; Woodvine, Bethany; Krishnamoorthy, Jothilatha; van Hoef, Vincent; Darini, Cedric; Kazimierczak, Urszula; Ah-son, Nicolas; Popper, Helmuth; Johnson, Myriam; Officer, Leah; Teodosio, Ana; Broggini, Massimo; Mann, Koren K.; Hatzoglou, Maria; Topisirovic, Ivan; Larsson, Ola; Le Quesne, John; Koromilas, Antonis E. 分享 收藏
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth (Jun, 10.1038/s41589-021-00813-7, 2021) Lee, Bianca J.; Boyer, Jacob A.; Burnett, G. Leslie; Thottumkara, Arun P.; Tibrewal, Nidhi; Wilson, Stacy L.; Hsieh, Tientien; Marquez, Abby; Lorenzana, Edward G.; Evans, James W.; Hulea, Laura; Kiss, Gert; Liu, Hui; Lee, Dong; Larsson, Ola; McLaughlan, Shannon; Topisirovic, Ivan; Wang, Zhengping; Wang, Zhican; Zhao, Yongyuan; Wildes, David; Aggen, James B.; Singh, Mallika; Gill, Adrian L.; Smith, Jacqueline A. M.; Rosen, Neal 分享 收藏
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth Lee, Bianca J.; Boyer, Jacob A.; Burnett, G. Leslie; Thottumkara, Arun P.; Tibrewal, Nidhi; Wilson, Stacy L.; Hsieh, Tientien; Marquez, Abby; Lorenzana, Edward G.; Evans, James W.; Hulea, Laura; Kiss, Gert; Liu, Hui; Lee, Dong; Larsson, Ola; McLaughlan, Shannon; Topisirovic, Ivan; Wang, Zhengping; Wang, Zhican; Zhao, Yongyuan; Wildes, David; Aggen, James B.; Singh, Mallika; Gill, Adrian L.; Smith, Jacqueline A. M.; Rosen, Neal 分享 收藏
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