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B

Besim Öğretmen

Medical University of South Carolina
H指数:62
被引数:2.1万

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Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program

鞘脂合成通过YAP驱动的再生程序介导结直肠癌转移

Science
IF45.8
2026-09-240
PRE
Swagata Goswami; Qiming Zhang; Abdullah Burak Yildiz; Upasana Das Adhikari; Akhouri Kishore Raghawan; Manon Bulliard; Sabhyata Sedhain; Odai Darawshi; Cigdem Elif Celik; Feyza Cansiz; Constantin P. Krempe; Jonas Rösler; Gabriele Allies; Sven W. Meckelmann; Chiashin Chi; Felix-Levin Hormann; Sven Heiles; Joseph Sedlak; Wesley Grace; George Eng; Ethan Reich; Chiara Alquati; Kevin J. Williams; Benjamin J. Read; Edrees H. Rashan; Zhixin Li; Anup Jnawali; Jose A. Ortiz; Chesta Jain; Charles A. Whittaker; Osman H. Yilmaz; Vikram Deshpande; Oliver J. Schmitz; Albert Sickmann; Autumn G. York; Douglas S. Kwon; Ulf Neumann; Maria Fedorova; Matthew G. Vander Heiden; Besim Ogretmen; Nilay S. Sethi; Alpaslan Tasdogan; Ömer H. Yilmaz
Sphingosine kinase-2 inhibition promotes immunogenic differentiation of myeloid-derived suppressor cells through an Acetyl-CoA carboxylase-phosphatidylcholine axis

鞘氨醇激酶-2抑制通过乙酰辅酶A羧化酶-磷脂酰胆碱轴促进髓源性抑制细胞的免疫原性分化

Nature Communications
IF15.7
2026-06-020
OAAI
Paramita Chakraborty; Shilpak Chatterjee; Mohamed Faisal Kassir; Wyatt Wofford; Seungho Choi; Natalia Oleinik; Ozge Saatci; Odai Darawshi; Satyajit Das; Nathaniel Oberhoeltzer; Anupam Gautam; Stephanie Mills; Reid DeMass; Zacharia Hedley; Yueying Liu; Rasesh Y. Parikh; Sandip Paul; Souvik Seal; Charles D. Smith; Michael B. Lilly; Vamsi K. Gangaraju; Yuri Peterson; Meenal Mehrotra; Elizabeth Hill; Ozgur Sahin; Norbert Leitinger; Paulo C. Rodriguez; Besim Ogretmen; Shikhar Mehrotra
Phase II Trial of Opaganib Addition in Metastatic Castration-Resistant Prostate Cancer After Disease Progression on Abiraterone or Enzalutamide

II期临床试验：在阿比特龙或恩扎卢amide治疗进展后的转移性去势抵抗性前列腺癌中添加奥帕吉布

Cancer Medicine
IF3.1
2026-04-140
OAAI
Jacqueline T. Brown; Bassel Nazha; Anna C. Ferreira; Kent Armeson; Elizabeth G. Hill; Besim Ogretmen; Shikhar Mehrotra; Alan Brisendine; George Magrath; Terry F. Plasse; Theodore Stewart Gourdin; Omer Kucuk; Michael Lilly
Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 T cells to impair antitumor immunity

棕榈酸诱导的线粒体损伤限制了CD8 T细胞中的组蛋白乙酰化，从而损害抗肿瘤免疫。

Science Immunology
IF16.3
2026-03-270
PRE
Silvia Tiberti; Sara Gennari; Martina Romeo; Ilir Sheraj; Mohamed Faisal Kassir; Juan Fernández-García; Carina B. Nava Lauson; Roberta Noberini; Carlotta Catozzi; Tiziano Dallavilla; Mattia Ballerini; Alessia Loffreda; Simona G. Codreanu; Stacy D. Sherrod; Katrina L. Leaptrot; Alexandra C. Schrimpe-Rutledge; John A. McLean; Martin H. Schaefer; Simona Rodighiero; Tiziana Bonaldi; Sarah-Maria Fendt; Besim Ogretmen; Sara Sdelci; Luigi Nezi; Teresa Manzo
Phosphorylation of an RNA-Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging
AGING CELL
IF7.1
2025-03-110
OAAI
Yeom, Eunbyul; Mun, Hyejin; Lim, Jinhwan; Chun, Yoo Lim; Min, Kyung-Won; Lambert, Johana; Cowart, L. Ashley; Pierce, Jason S.; Ogretmen, Besim; Cho, Jung-Hyun; Chang, Jeong Ho; Buchan, J. Ross; Pitt, Jason; Kaeberlein, Matt; Kang, Sung-Ung; Kwon, Eun-Soo; Ko, Seungbeom; Choi, Kyoung-Min; Lee, Yong Sun; Ha, Yoon-Su; Kim, Seung-Jin; Lee, Kwang-Pyo; Kim, Hyo-Sung; Yang, Seo Young; Shin, Chang Hoon; Yoon, Je-Hyun; Lee, Kyu-Sun
Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma
FRONTIERS IN IMMUNOLOGY
IF5.9
2025-01-270
OAAI
Yoon, Angela J.; Carvajal, Richard D.; Graboyes, Evan M.; Kaczmar, John M.; Albergotti, William G.; Kejner, Alexandra E.; Troob, Scott H.; Philipone, Elizabeth; Anoma, Jean-Sebastien; Armeson, Kent E.; Hill, Elizabeth G.; Richardson, Mary S.; Woods, Tina R.; Chera, Bhishamjit S.; Nourollah-Zadeh, Farzad; Lee, Byung J.; Pandruvada, Subramanya; Kourtidis, Antonis; Kingsley, Christina; O'Quinn, Elizabeth C.; Mills, Stephanie; Jordan, Victoria C.; Spencer, Mike; Fails, Danielle; Mckee, Trevor D.; Zaidi, Mark; Brisendine, Alan; Horn, Shane; Mehrotra, Shikhar; Ogretmen, Besim; Newman, Jason G.
H2S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response
SCIENCE ADVANCES
IF12.5
2024-11-150
OAAI
Oberholtzer, Nathaniel; Chakraborty, Paramita; Kassir, Mohamed Faisal; Dressman, James; Das, Satyajit; Mills, Stephanie; Comte-Walters, Susana; Gooz, Monika; Choi, Seungho; Parikh, Rasesh Y.; Hedley, Zacharia; Vaena, Silvia; Demass, Reid; Scurti, Gina; Romeo, Martin; Gangaraju, Vamsi K.; Berto, Stefano; Hill, Elizabeth; Ball, Lauren E.; Mehta, Anand S.; Maldonado, Eduardo N.; Nishimura, Michael I.; Ogretmen, Besim; Mehrotra, Shikhar
Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER plus breast cancer
CELL DEATH & DISEASE
IF9.6
2024-06-157
OAAI
Saatci, Ozge; Alam, Rashedul; Huynh-Dam, Kim-Tuyen; Isik, Aynur; Uner, Meral; Belder, Nevin; Ersan, Pelin Gulizar; Tokat, Unal Metin; Ulukan, Burge; Cetin, Metin; Calisir, Kubra; Gedik, Mustafa Emre; Bal, Hilal; Sahin, Ozlem Sener; Riazalhosseini, Yasser; Thieffry, Denis; Gautheret, Daniel; Ogretmen, Besim; Aksoy, Sercan; Uner, Aysegul; Akyol, Aytekin; Sahin, Ozgur

研究方向

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C
Can E. Senkal
H 指数:28论文数:63被引数:4,169
Y
Yusuf A. Hannun
H 指数:138论文数:742被引数:7.4万
N
Natalia V. Oleinik
H 指数:22论文数:88被引数:1,757
S
Shikhar Mehrotra
H 指数:44论文数:290被引数:5,801
Z
Zdzisław M. Szulc
H 指数:46论文数:151被引数:6,395
S
Shanmugam Panneer Selvam
H 指数:17论文数:28被引数:2,344
J
Jacek Bielawski
H 指数:68论文数:271被引数:1.3万
S
Suriyan Ponnusamy
H 指数:29论文数:111被引数:3,339
S
Salih Gencer
H 指数:15论文数:42被引数:1,512
L
Lina M. Obeid
H 指数:0论文数:0被引数:193