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收藏分享 收藏 分享 收藏 分享 收藏 Mutant p53 gain of function mediates cancer immune escape that is counteracted by APR-246
Zhou, Xiaolei; Santos, Gema Sanz; Zhan, Yue; Oliveira, Mariana M. S.; Rezaei, Shiva; Singh, Madhurendra; Peuget, Sylvain; Westerberg, Lisa S.; Johnsen, John Inge; Selivanova, Galina 分享 收藏 分享 收藏 Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small MoleculeGrinkevich, Vera V.; Vema, Aparna; Fawkner, Karin; Issaeva, Natalia; Andreotti, Virginia; Dickinson, Eleanor R.; Hedstrom, Elisabeth; Spinnler, Clemens; Inga, Alberto; Larsson, Lars-Gunnar; Karlen, Anders; Wilhelm, Margareta; Barran, Perdita E.; Okorokov, Andrei L.; Selivanova, Galina; Zawacka-Pankau, Joanna E. 分享 收藏 分享 收藏 Pharmacologic Activation of p53 Triggers Viral Mimicry Response Thereby Abolishing Tumor Immune Evasion and Promoting Antitumor ImmunityZhou, Xiaolei; Singh, Madhurendra; Santos, Gema Sanz; Guerlavais, Vincent; Carvajal, Luis A.; Aivado, Manuel; Zhan, Yue; Oliveira, Mariana M. S.; Westerberg, Lisa S.; Annis, D. Allen; Johnsen, John Inge; Selivanova, Galina 分享 收藏 Identification and targeting of selective vulnerability rendered by tamoxifen resistanceSingh, Madhurendra; Zhou, Xiaolei; Chen, Xinsong; Santos, Gema Sanz; Peuget, Sylvain; Cheng, Qing; Rihani, Ali; Arner, Elias S. J.; Hartman, Johan; Selivanova, Galina 分享 收藏 Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer CompoundsPeuget, Sylvain; Zhu, Jiawei; Sanz, Gema; Singh, Madhurendra; Gaetani, Massimiliano; Chen, Xinsong; Shi, Yao; Saei, Amir Ata; Visnes, Torkild; Lindstrom, Mikael S.; Rihani, Ali; Moyano-Galceran, Lidia; Carlson, Joseph W.; Hjerpe, Elisabet; Joneborg, Ulrika; Lehti, Kaisa; Hartman, Johan; Helleday, Thomas; Zubarev, Roman; Selivanova, Galina 分享 收藏 分享 收藏 分享 收藏 RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activityRistau, Johannes; van Hoef, Vincent; Peuget, Sylvain; Zhu, Jiawei; Guan, Bo-Jhih; Liang, Shuo; Hatzoglou, Maria; Topisirovic, Ivan; Selivanova, Galina; Larsson, Ola 分享 收藏 Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemiaDemir, Salih; Boldrin, Elena; Sun, Qian; Hampp, Stephanie; Tausch, Eugen; Eckert, Cornelia; Ebinger, Martin; Handgretinger, Rupert; te Kronnie, Geertruy; Wiesmueller, Lisa; Stilgenbauer, Stephan; Selivanova, Galina; Debatin, Klaus-Michael; Meyer, Lueder Hinrich 分享 收藏 分享 收藏 分享 收藏 MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblastsZhang, Fan; Zakaria, Siti Mariam; Tabor, Vedrana Hogqvist; Singh, Madhurendra; Tronnersjo, Susanna; Goodwin, Jacob; Selivanova, Galina; Bartek, Jiri; Castell, Alina; Larsson, Lars-Gunnar 分享 收藏 Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs (vol 280, pg 30384, 2005)Bykov, Vladimir J. N.; Issaeva, Natalia; Zache, Nicole; Shilov, Alexandre; Hultcrantz, Monica; Bergman, Jan; Selivanova, Galina; Wiman, Klas G. 分享 收藏 APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase (vol 4, e881, 2013)Peng, Xiaoxiao; Zhang, Mei-Qiong-Zi; Conserva, Francesca; Hosny, Gihan; Selivanova, Galina; Bykov, Vladimir J. N.; Arner, Elias S. J.; Wiman, Klas G. 分享 收藏 
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