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Microbiome Modulation as a Strategy to Enhance Immunotherapy in Metastatic CRC Walker, Maria; Gottier, Claudia; Poehlmann, Doris; Determann, Madita; Thomas, Carolin; Wilmink, Marijn; Linzmeier, Luise; Dobernig, Vanessa; Truscello, Luca; Walberg, Asa; Schwarzfischer, Marlene; Morsy, Yasser; Greten, Florian; Scharl, Michael 分享 收藏
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T-cell specific in vivo gene delivery with DART-AAVs targeted to CD8 靶向CD8的dart-aavs的T细胞特异性体内基因递送 Demircan, Muhammed Burak; Zinser, Luca J.; Michels, Alexander; Guaza-Lasheras, Mar; John, Fabian; Gorol, Johanna M.; Theuerkauf, Samuel A.; Guenther, Dorothee M.; Grimm, Dirk; Greten, Florian R.; Chlanda, Petr; Thalheimer, Frederic B.; Buchholz, Christian J. 分享 收藏
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer ZEB1-mediated成纤维细胞极化控制结直肠癌的炎症和对免疫疗法的敏感性 Menche, Constantin; Schuhwerk, Harald; Armstark, Isabell; Gupta, Pooja; Fuchs, Kathrin; van Roey, Ruthger; Mosa, Mohammed H.; Hartebrodt, Anne; Hajjaj, Yussuf; Ezquerra, Ana Clavel; Selvaraju, Manoj K.; Geppert, Carol, I; Baerthel, Stefanie; Saur, Dieter; Greten, Florian R.; Brabletz, Simone; Blumenthal, David B.; Weigert, Andreas; Brabletz, Thomas; Farin, Henner F.; Stemmler, Marc P. 分享 收藏
A guideline on the molecular ecosystem regulating ferroptosis 调控铁死亡的分子生态系统指南 Dai, Enyong; Chen, Xin; Linkermann, Andreas; Jiang, Xuejun; Kang, Rui; Kagan, Valerian E.; Bayir, Huelya; Yang, Wan Seok; Garcia-Saez, Ana J.; Ioannou, Maria S.; Janowitz, Tobias; Ran, Qitao; Gu, Wei; Gan, Boyi; Krysko, Dmitri V.; Zhu, Xiaofeng; Wang, Jiayi; Krautwald, Stefan; Toyokuni, Shinya; Xie, Yangchun; Greten, Florian R.; Yi, Qing; Schick, Joel; Liu, Jiao; Gabrilovich, Dmitry I.; Liu, Jinbao; Zeh, Herbert J.; Zhang, Donna D.; Yang, Minghua; Iovanna, Juan; Kopf, Manfred; Adolph, Timon E.; Chi, Jen-Tsan; Li, Changfeng; Ichijo, Hidenori; Karin, Michael; Sankaran, Vijay G.; Zou, Weiping; Galluzzi, Lorenzo; Bush, Ashley I.; Li, Binghui; Melino, Gerry; Baehrecke, Eric H.; Lotze, Michael T.; Klionsky, Daniel J.; Stockwell, Brent R.; Kroemer, Guido; Tang, Daolin 分享 收藏
Single-cell deconvolution reveals high lineage- and location-dependent heterogeneity in mesenchymal multivisceral stage 4 colorectal cancer Berlin, Christopher; Mauerer, Bernhard; Cauchy, Pierre; Luenstedt, Jost; Sankowski, Roman; Marx, Lisa; Feuerstein, Reinhild; Schaefer, Luisa; Greten, Florian R.; Pesic, Marina; Gross, Olaf; Prinz, Marco; Ruehl, Naomi; Miketiuk, Laura; Jauch, Dominik; Laessle, Claudia; Jud, Andreas; Biesel, Esther A.; Neeff, Hannes; Fichtner-Feigl, Stefan; Holzner, Philipp A.; Kesselring, Rebecca 分享 收藏
Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses Farin, Henner F.; Mosa, Mohammed H.; Ndreshkjana, Benardina; Grebbin, Britta M.; Ritter, Birgit; Menche, Constantin; Kennel, Kilian B.; Ziegler, Paul K.; Szabo, Lili; Bollrath, Julia; Rieder, Dietmar; Michels, Birgitta E.; Kress, Alena; Bozlar, Muege; Darvishi, Tahmineh; Stier, Sara; Kur, Ivan-Maximilano; Bankov, Katrin; Kesselring, Rebecca; Fichtner-Feigl, Stefan; Bruene, Bernhard; Goetze, Thorsten O.; Al-Batran, Salah-Eddin; Brandts, Christian H.; Bechstein, Wolf O.; Wild, Peter J.; Weigert, Andreas; Mueller, Susanne; Knapp, Stefan; Trajanoski, Zlatko; Greten, Florian R. 分享 收藏
Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure Schierwagen, Robert; Gu, Wenyi; Brieger, Angela; Bruene, Bernhard; Ciesek, Sandra; Dikic, Ivan; Dimmeler, Stefanie; Geisslinger, Gerd R.; Greten, Florian; Hermann, Eva; Hildt, Eberhard; Kempf, Volkhard A. J.; Klein, Sabine; Koch, Ina; Muehl, Heiko; Mueller, Volker; Peiffer, Kai-Henrik; Kestner, Roxane-Isabelle; Piiper, Albrecht; Rohde, Gernot; Scholich, Klaus H.; Schulz, Marcel; Storf, Holger; Toptan, Tuna; Vasa-Nicotera, Mariuca; Vehreschild, Maria J. G. T.; Weigert, Andreas J.; Wild, Peter; Zeuzem, Stefan; Engelmann, Cornelius; Schaefer, Liliana; Welsch, Christoph; Trebicka, Jonel 分享 收藏
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy 癌细胞中STING信号的综合实施使免疫微环境适合检查点抑制剂治疗 Vornholz, Larsen; Isay, Sophie E.; Kurgyis, Zsuzsanna; Strobl, Daniel C.; Loll, Patricia; Mosa, Mohammed H.; Luecken, Malte D.; Sterr, Michael; Lickert, Heiko; Winter, Christof; Greten, Florian R.; Farin, Henner F.; Theis, Fabian J.; Ruland, Juergen 分享 收藏
Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression SUV420H2-Dependent染色质压缩的丧失驱动右半结肠癌进展 Boonsanay, Boonsanay; Mosa, Mohammed H.; Looso, Mario; Weichenhan, Dieter; Ceteci, Fatih; Pudelko, Lorenz; Lechel, Andre; Michel, Christian S.; Kuenne, Carsten; Farin, Henner F.; Plass, Christoph; Greten, Florian R. 分享 收藏
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Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer Olfactomedin 4与分化标志物的表达相关，但与结直肠癌的癌症干细胞，EMT或转移扩散的特性无关 Jaitner, Stefanie; Pretzsch, Elise; Neumann, Jens; Schaeffauer, Achim; Schiemann, Matthias; Angele, Martin; Kumbrink, Joerg; Schwitalla, Sarah; Greten, Florian R.; Brandl, Lydia; Klauschen, Frederick; Horst, David; Kirchner, Thomas; Jung, Andreas 分享 收藏
Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy Denk, Dominic; Petrocelli, Valentina; Conche, Claire; Drachsler, Moritz; Ziegler, Paul K.; Braun, Angela; Kress, Alena; Nicolas, Adele M.; Mohs, Kathleen; Becker, Christoph; Neurath, Markus F.; Farin, Henner F.; Buchholz, Christian J.; Andreux, Penelope A.; Rinsch, Chris; Greten, Florian R. 分享 收藏
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IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Cells (vol 7, pg 1914, 2014) Goktuna, Serkan I.; Canli, Ozge; Bollrath, Julia; Fingerle, Alexander A.; Horst, David; Diamanti, Michaela A.; Pallangyo, Charles; Bennecke, Moritz; Nebelsiek, Tim; Mankan, Arun K.; Lang, Roland; Artis, David; Hu, Yinling; Patzelt, Thomas; Ruland, Jurgen; Kirchner, Thomas; Taketo, M. Mark; Chariot, Alain; Arkan, Melek C.; Greten, Florian R. 分享 收藏
Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis 癌症相关成纤维细胞中前列腺素E2信号的破坏限制了乳腺癌的生长，但促进了转移 Elwakeel, Eiman; Brueggemann, Mirko; Wagih, Jessica; Lityagina, Olga; Elewa, Mohammed A. F.; Han, Yingying; Froemel, Timo; Popp, Ruediger; Nicolas, Adele M.; Schreiber, Yannick; Gradhand, Elise; Thomas, Dominique; Nuesing, Rolf; Steinmetz-Spaeh, Julia; Savai, Rajkumar; Fokas, Emmanouil; Fleming, Ingrid; Greten, Florian R.; Zarnack, Kathi; Bruene, Bernhard; Weigert, Andreas 分享 收藏
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