Volker Hovestadt - Publications, H-index & Citations

Volker Hovestadt

Dana-Farber Cancer Institute

80H指数

356论文数

4.6W被引数

收录论文 94

发表时间

Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency 不同小脑髓母细胞瘤染色质状态揭示KDM2B为一种选择性依赖

Nature Genetics

IF29

2026-09-24

OAAI

Ran Tao; Serap Erkek-Ozhan; Beisi Xu; Yurika Matsui; Priya Mittal; Kyle S. Smith; Yiran Li; David Filipovic; Ruijie Xu; Qingsong Gao; Emily Darrow; Rahul Kumar; Nadhir Djekidel; Richa Bajpai; Jennifer Hadley; Melissa Batts; Sara A. Lewis; Taha Soliman; Colleen Reilly; Natarajan V. Bhanu; Leena Paul; Hong Lin; Brian Gudenas; Kim Lowe; Marc Zapatka; Laura Sieber; David T. W. Jones; Marcel Kool; Sebastian M. Waszak; Volker Hovestadt; Ivo Buchhalter; Marina Ryzhova; Andrey Korshunov; Peter Lichter; Lukas Chavez; Lena M. Kutscher; Benjamin A. Garcia; Shondra M. Pruett-Miller; Xin Zhou; Brent A. Orr; Giles W. Robinson; Gang Wu; Jan O. Korbel; Jamy C. Peng; Stefan M. Pfister; Paul A. Northcott

A cellular epigenetic classification system for glioblastoma 胶质母细胞瘤的细胞表观遗传分类系统

Neuro-Oncology

IF13.4

2026-04-01

PREAI

Silverbush, Dana; Jurgensen, Liv; Freeburg, Nelson F.; Pooley, Channing S.; Boniolo, Fabio; Gaiti, Federico; Suva, Mario L.; Hovestadt, Volker

A microenvironment-determined risk continuum refines subtyping in meningioma and reveals determinants of machine learning-based tumor classification 微环境确定的风险连续体可改善脑膜瘤的亚型，并揭示基于机器学习的肿瘤分类的决定因素

Nature Genetics

IF29

2026-02-09

OAAI

Sybren L. N. Maas; Yiheng Tang; Eric Stutheit-Zhao; Ramin Rahmanzade; Christina Blume; Thomas Hielscher; Ferdinand Zettl; Salvatore Benfatto; Domenico Calafato; Martin Sill; Jasim Kada Benotmane; Yahaya A. Yabo; Felix Behling; Abigail Suwala; Helin Kardo; Michael Ritter; Matthieu Peyre; Roman Sankowski; Konstantin Okonechnikov; Philipp Sievers; Areeba Patel; David Reuss; Mirco J. Friedrich; Damian Stichel; Daniel Schrimpf; Thierry P. P. Van den Bosch; Katja Beck; Hans-Georg Wirsching; Gerhard Jungwirth; C. Oliver Hanemann; Katrin Lamszus; Nima Etminan; Andreas Unterberg; Christian Mawrin; Marc Remke; Olivier Ayrault; Peter Lichter; Guido Reifenberger; Michael Platten; Tim Kacprowski; Markus List; Josch K. Pauling; Jan Baumbach; Till Milde; Rachel Grossmann; Zvi Ram; Miriam Ratliff; Jan-Philipp Mallm; Marian C. Neidert; Eelke M. Bos; Marco Prinz; Michael Weller; Till Acker; Felix J. Hartmann; Matthias Preusser; Ghazaleh Tabatabai; Christel Herold-Mende; Sandro M. Krieg; David T. W. Jones; Stefan M. Pfister; Wolfgang Wick; Michel Kalamarides; Andreas von Deimling; Dieter Henrik Heiland; Volker Hovestadt; Moritz Gerstung; Matthias Schlesner; Felix Sahm

Nanopore DNA Methylation Sequencing Simulates Rapid Intraoperative Diagnosis of Pediatric Brain Tumors 纳米孔DNA甲基化测序模拟快速术中诊断儿童脑肿瘤

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Jarvis, Casey; Benfatto, Salvatore; Castellani, Sophia; Couvillon, Elsa; Abdullaev, Ziedulla; Lidov, Hart; Adalpe, Kenneth; Hovestadt, Volker; Alexandrescu, Sanda; Filbin, Mariella; Baird, Lissa

MACHINE LEARNING AND MULTI-OMIC ANALYSIS IDENTIFY A MICROENVIRONMENT-DRIVEN MENINGIOMA RISK CONTINUUM UNDERLYING MOLECULAR CLASSIFICATIONS 机器学习和多组学分析识别出一种由微环境驱动的、与分子分类相关的脑膜瘤风险连续体

NEURO-ONCOLOGY

IF13.4

2025-11-01

PREAI

Maas, Sybren; Tang, Yiheng; Stutheit-Zhao, Eric; Rahmanzade, Ramin; Hielscher, Thomas; Zettl, Ferdinand; Benfatto, Salvatore; Calafato, Domenico; Sill, Martin; Benotmane, Jasim Kada; Yabo, Yahaya; Peyre, Matthieu; Sankowski, Roman; Okonechnikov, Konstantin; Sievers, Philip; Patel, Areeba; Reuss, David; Hanemann, Oliver; Lamszus, Katrin; Etminan, Nima; Unterberg, Andreas; Mawrin, Christian; Grossmann, Rachel; Ram, Zvi; Ratliff, Miriam; Neidert, Marian; Bos, Eelke; Prinz, Marco; Weller, Michael; Acker, Till; Hartmann, Felix; Preusser, Matthias; Tabatabai, Ghazaleh; Herold-Mende, Christel; Krieg, Sandro; Jones, David; Pfister, Stefan; Wick, Wolfgang; Kalamarides, Michel; Von Deimling, Andreas; Heiland, Dieter Henrik; Hovestadt, Volker; Gerstung, Moritz; Schlesner, Matthias; Sahm, Felix

Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions 胚胎性多分层菊形团肿瘤的细胞层次结构由致癌microRNAs和受体-配体相互作用塑造。

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Gabler-Pamer, Lisa; Beck, Alexander; Cruzeiro, Gustavo Alencastro Veiga; Lambo, Sander; Shaw, Mckenzie L.; Hack, Olivia A.; Nascimento, Andrezza; Madlener, Sibylle; Lotsch, Daniela; Slavc, Irene; Dorfer, Christian; Haberler, Christine; Baird, Lissa; Chi, Susan N.; Alexandrescu, Sanda; Gojo, Johannes; Marcel, Kool; Hovestadt, Volker; Filbin, Mariella G.

Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard Pipeline Olympics：针对DNA甲基化测序数据，基于实验金标准的可延续性计算工作流基准测试

NUCLEIC ACIDS RESEARCH

IF13.1

2025-10-28

OAAI

Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo

In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas 基于计算机的纯化提高了儿科低级别胶质瘤的DNA甲基化分类率

Acta Neuropathologica

IF9.3

2025-09-27

OAAI

Liv Jürgensen; Salvatore Benfatto; Simone Schmid; Bjarne Daenekas; Julia Großer; Pablo Hernáiz Driever; Arend Koch; David Capper; Volker Hovestadt

CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias MECOM对CEBPA的抑制阻止了分化，从而驱动了侵袭性白血病。

Blood

IF23.1

2025-09-26

OAAI

Travis J. Fleming; Mateusz Antoszewski; Sander Lambo; Michael C. Gundry; Riccardo Piussi; Lara Wahlster; Sanjana Shah; Fiona E. Reed; Kevin D. Dong; Joao A. Paulo; Steven P. Gygi; Claudia Mimoso; Seth R. Goldman; Karen Adelman; Jennifer A. Perry; Yana Pikman; Kimberly Stegmaier; Maria N. Barrachina; Kellie R. Machlus; Volker Hovestadt; Andrea Arruda; Mark D. Minden; Richard A. Voit; Vijay G. Sankaran

Clinical and Molecular Characteristics of 100 Atypical Teratoid Rhabdoid Tumor Patients from Low- and Middle-Income Countries 低中收入国家100例不典型畸胎瘤样横纹肌样瘤患者的临床与分子特征

Cancers 2025, Vol. 17, Page 3077

IF0

2025-09-23

OAAI

Noha A. Ismail; Shaimaa Aboubakr; Amal Mosaab; Eslam Maher; Hanafy Hafez; Hala Taha; Dina Yassin; Amal Refaat; Mohamed S. Zaghloul; Mohamed El-Beltagy; Abdelrahman Enayat; Volker Hovestadt; Olfat Ahmed; Mark W. Kieran; Ahmed El-Hemaly; Shahenda EI-Naggar; Alaa El-Haddad

Rapid epigenomic classification of acute leukemia 急性白血病的快速表观基因组分类

Nature Genetics

IF0

2025-09-22

OAAI

Til L. Steinicke; Salvatore Benfatto; Maria R. Capilla-Guerra; Andre B. Monteleone; Jonathan H. Young; Subha Shankar; Phillip D. Michaels; Harrison K. Tsai; Jonathan D. Good; Antonia Kreso; Peter van Galen; Christoph Schliemann; Evan C. Chen; Gabriel K. Griffin; Volker Hovestadt

Lack of evidence for the transitional cerebellar progenitor 缺乏过渡性小脑祖细胞的证据

Nature

IF48.5

2025-07-09

PREAI

Kyle S. Smith; Yiran Li; Parthiv Haldipur; Brian L. Gudenas; Kathleen J. Millen; Volker Hovestadt; Paul A. Northcott

Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions 胚胎性多层层状-rosettes肿瘤的细胞层次结构由致癌microRNAs和受体-配体相互作用塑造。

NATURE CANCER

IF28.5

2025-05-26

OAAI

Beck, Alexander; Gabler-Pamer, Lisa; Alencastro Veiga Cruzeiro, Gustavo; Lambo, Sander; Englinger, Bernhard; Shaw, McKenzie L.; Hack, Olivia A.; Liu, Ilon; Haase, Rebecca D.; de Biagi Jr, Carlos A. O.; Baumgartner, Alicia; Nascimento Silva, Andrezza Do; Klenner, Marbod; Freidel, Pia S.; Herms, Jochen; von Baumgarten, Louisa; Tonn, Joerg C.; Thon, Niklas; Bruckner, Katharina; Madlener, Sibylle; Mayr, Lisa; Senfter, Daniel; Peyrl, Andreas; Slavc, Irene; Loetsch, Daniela; Dorfer, Christian; Geyregger, Rene; Amberg, Nicole; Haberler, Christine; Mack, Norman; Schwalm, Benjamin; Pfister, Stefan M.; Korshunov, Andrey; Baird, Lissa C.; Yang, Edward; Chi, Susan N.; Alexandrescu, Sanda; Gojo, Johannes; Kool, Marcel; Hovestadt, Volker; Filbin, Mariella G.

GENE REGULATORY NETWORK LANDSCAPE OF GROUP 3/4 MEDULLOBLASTOMA

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Joshi, Piyush; Stelzer, Tamina; Okonechnikov, Konstantin; Sarropoulos, Ioannis; Sepp, Mari; Pour-Jamnani, Mischan, V; Rademacher, Anne; Yamada-Saito, Tetsuya; Schneider, Celine; Schmidt, Julia; Schaefer, Philipp; Leiss, Kevin; Bortolomeazzi, Michele; Mallm, Jan-Philipp; da Silva, Patricia B. G.; Statz, Britta; Wittmann, Andrea; Schramm, Kathrin; Blattner-Johnson, Mirjam; Fiesel, Petra; Jones, Barbara; Milde, Till; Pajtler, Kristian; van Tilburg, Cornelis M.; Witt, Olaf; Rippe, Karsten; Korshunov, Andrey; Jones, David T. W.; Hovestadt, Volker; Northcott, Paul A.; Thongjuea, Supat; Jaeger, Natalie; Kaessmann, Henrik; Pfister, Stefan M.; Kutscher, Lena M.

MULTI-OMICS SEQUENCING OF ATYPICAL TERATOID RHABDOID TUMORS UNVEILS A SHARED GROUND-STATE POPULATION PROMOTING SUBGROUP-SPECIFIC DIFFERENTIATION TRAJECTORIES

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Carmona, Enrique Blanco; Paassen, Irene; He, Jiayou; Buellesbach, Annette; Buhl, Juliane L.; Federico, Aniello; Liu, Ilon; Young, Matthew; Kildisiute, Gerda; Behjati, Sam; Vibhakar, Rajeev; Donson, Andrew; Foreman, Nicholas; Hovestadt, Volker; Shaw, McKenzie; Chi, Susan N.; Fruehwald, Michael; Korshunov, Andrey; Hasselblatt, Martin; Hoving, Eelco W.; Jaeger, Natalie; Johann, Pascal D.; Pfister, Stefan M.; Filbin, Mariella; Drost, Jarno; Kool, Marcel

BCOR/L1-ALTERATIONS REWIRE HISTONE REGULATION TO INDUCE ONCOGENIC PATHWAYS IN PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS BCOR/L1-ALTERATIONS重新连接组蛋白调控以诱导小儿中枢神经系统肿瘤的致癌途径

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Bruckner, Katharina; Loetsch-Gojo, Daniela; Gabler, Lisa; Wang, Shanzheng; Kirchhofer, Dominik; Labelle, Jenna; Madlener, Sibylle; Senfter, Daniel; Schmitt-Hoffner, Felix; Federico, Aniello; Koster, Jan; Dorfer, Christian; Tauziede-Espariat, Arnault; Pahnke, Jens; Hovestadt, Volker; Beck, Alexander; Schueler, Julia; Haberler, Christine; Berger, Walter; Filbin, Mariella G.; Kool, Marcel; Gojo, Johannes

A prognostic neural epigenetic signature in high-grade glioma 高级别胶质瘤的预后神经表观遗传特征

NATURE MEDICINE

IF50

2024-05-17

OAAI

Drexler, Richard; Khatri, Robin; Sauvigny, Thomas; Mohme, Malte; Maire, Cecile L.; Ryba, Alice; Zghaibeh, Yahya; Duehrsen, Lasse; Salviano-Silva, Amanda; Lamszus, Katrin; Westphal, Manfred; Gempt, Jens; Wefers, Annika K.; Neumann, Julia E.; Bode, Helena; Hausmann, Fabian; Huber, Tobias B.; Bonn, Stefan; Juetten, Kerstin; Delev, Daniel; Weber, Katharina J.; Harter, Patrick N.; Onken, Julia; Vajkoczy, Peter; Capper, David; Wiestler, Benedikt; Weller, Michael; Snijder, Berend; Buck, Alicia; Weiss, Tobias; Goeller, Pauline C.; Sahm, Felix; Menstel, Joelle Aline; Zimmer, David Niklas; Keough, Michael B.; Ni, Lijun; Monje, Michelle; Silverbush, Dana; Hovestadt, Volker; Suva, Mario L.; Krishna, Saritha; Hervey-Jumper, Shawn L.; Schueller, Ulrich; Heiland, Dieter H.; Haenzelmann, Sonja; Ricklefs, Franz L.

Modeling epigenetic lesions that cause gliomas 模拟导致胶质瘤的表观遗传病变

CANCER RESEARCH

IF16.6

2024-03-04

PREAI

Rahme, Gilbert J.; Javed, Nauman M.; Puorro, Kaitlyn L.; Xin, Shouhui; Hovestadt, Volker; Johnstone, Sarah E.; Bernstein, Bradley E.

Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma

ACTA NEUROPATHOLOGICA

IF9.3

2024-01-20

OAAI

Drexler, Richard; Khatri, Robin; Schueller, Ulrich; Eckhardt, Alicia; Ryba, Alice; Sauvigny, Thomas; Duehrsen, Lasse; Mohme, Malte; Ricklefs, Tammo; Bode, Helena; Hausmann, Fabian; Huber, Tobias B.; Bonn, Stefan; Voss, Hannah; Neumann, Julia E.; Silverbush, Dana; Hovestadt, Volker; Suva, Mario L.; Lamszus, Katrin; Gempt, Jens; Westphal, Manfred; Heiland, Dieter H.; Haenzelmann, Sonja; Ricklefs, Franz L.

Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology (vol 29, pg 917, 2023)多体神经病理学提高了小儿神经肿瘤学的诊断准确性 (第29卷，917页，2023)

NATURE MEDICINE

IF50

2023-10-24

OAAI

Sturm, Dominik; Capper, David; Andreiuolo, Felipe; Gessi, Marco; Koelsche, Christian; Reinhardt, Annekathrin; Sievers, Philipp; Wefers, Annika K.; Ebrahimi, Azadeh; Suwala, Abigail K.; Gielen, Gerrit H.; Sill, Martin; Schrimpf, Daniel; Stichel, Damian; Hovestadt, Volker; Daenekas, Bjarne; Rode, Agata; Hamelmann, Stefan; Previti, Christopher; Jaeger, Natalie; Buchhalter, Ivo; Blattner-Johnson, Mirjam; Jones, Barbara C.; Warmuth-Metz, Monika; Bison, Brigitte; Grund, Kerstin; Sutter, Christian; Hirsch, Steffen; Dikow, Nicola; Hasselblatt, Martin; Schueller, Ulrich; Koch, Arend; Gerber, Nicolas U.; White, Christine L.; Buntine, Molly K.; Kinross, Kathryn; Algar, Elizabeth M.; Hansford, Jordan R.; Gottardo, Nicholas G.; Schuhmann, Martin U.; Thomale, Ulrich W.; Driever, Pablo; Gnekow, Astrid; Witt, Olaf; Mueller, Hermann L.; Calaminus, Gabriele; Fleischhack, Gudrun; Kordes, Uwe; Mynarek, Martin; Rutkowski, Stefan; Fruehwald, Michael C.; Kramm, Christof M.; von Deimling, Andreas; Pietsch, Torsten; Sahm, Felix; Pfister, Stefan M.; Jones, David. T. W.

研究方向