未登录.png)
分享.png)
收藏The Wnt-dependent master regulator NKX1-2 controls mouse pre-implantation developmentWnt依赖性主调节NKX1-2控制小鼠植入前发育
Nakagawa, Shoma; Carnevali, Davide; Tan, Xiangtian; Alvarez, Mariano J.; Parfitt, David-Emlyn; Di Vicino, Umberto; Arumugam, Karthik; Shin, William; Aranda, Sergi; Normanno, Davide; Sebastian-Perez, Ruben; Cannata, Chiara; Cortes, Paola; Neguembor, Maria Victoria; Shen, Michael M.; Califano, Andrea; Cosma, Maria Pia 分享 收藏 A Transcriptome-Based Precision Oncology Platform for Patient-Therapy Alignment in a Diverse Set of Treatment-Resistant MalignanciesMundi, Prabhjot S.; Cruz, Filemon S. Dela; Grunn, Adina; Diolaiti, Daniel; Mauguen, Audrey; Rainey, Allison R.; Guillan, Kristina; Siddiquee, Armaan; You, Daoqi; Realubit, Ronald; Karan, Charles; Ortiz, Michael V.; Douglass, Eugene F.; Accordino, Melissa; Mistretta, Suzanne; Brogan, Frances; Bruce, Jeffrey N.; Caescu, Cristina I.; Carvajal, Richard D.; Crew, Katherine D.; Decastro, Guarionex; Heaney, Mark; Henick, Brian S.; Hershman, Dawn L.; Hou, June Y.; Iwamoto, Fabio M.; Jurcic, Joseph G.; Kiran, Ravi P.; Kluger, Michael D.; Kreisl, Teri; Lamanna, Nicole; Lassman, Andrew B.; Lim, Emerson A.; Manji, Gulam A.; Mckhann, Guy M.; Mckiernan, James M.; Neugut, Alfred I.; Olive, Kenneth P.; Rosenblat, Todd; Schwartz, Gary K.; Shu, Catherine A.; Sisti, Michael B.; Tergas, Ana; Vattakalam, Reena M.; Welch, Mary; Wenske, Sven; Wright, Jason D.; Canoll, Peter; Hibshoosh, Hanina; Kalinsky, Kevin; Aburi, Mahalaxmi; Sims, Peter A.; Alvarez, Mariano J.; Kung, Andrew L.; Califano, Andrea 分享 收藏 分享 收藏 分享 收藏 Network-based assessment of HDAC6 activity predicts preclinical and clinical responses to the HDAC6 inhibitor ricolinostat in breast cancerZeleke, Tizita Z.; Pan, Qingfei; Chiuzan, Codruta; Onishi, Maika; Li, Yuxin; Tan, Haiyan; Alvarez, Mariano J.; Honan, Erin; Yang, Min; Chia, Pei Ling; Mukhopadhyay, Partha; Kelly, Sean; Wu, Ruby; Fenn, Kathleen; Trivedi, Meghna S.; Accordino, Melissa; Crew, Katherine D.; Hershman, Dawn L.; Maurer, Matthew; Jones, Simon; High, Anthony; Peng, Junmin; Califano, Andrea; Kalinsky, Kevin; Yu, Jiyang; Silva, Jose 分享 收藏 OncoLoop: A Network-Based Precision Cancer Medicine FrameworkVasciaveo, Alessandro; Arriaga, Juan Martin; de Almeida, Francisca Nunes; Zou, Min; Douglass Jr, Eugene F.; Picech, Florencia; Shibata, Maho; Rodriguez-Calero, Antonio; de Brot, Simone; Mitrofanova, Antonina; Chua, Chee Wai; Karan, Charles; Realubit, Ronald; Pampou, Sergey; Kim, Jaime Y.; Afari, Stephanie N.; Mukhammadov, Timur; Zanella, Luca; Corey, Eva; Alvarez, Mariano J.; Rubin, Mark A.; Shen, Michael M.; Califano, Andrea; Abate-Shen, Cory 分享 收藏 A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infectionLaise, Pasquale; Stanifer, Megan; Bosker, Gideon; Sun, Xiaoyun; Triana, Sergio; Doldan, Patricio; La Manna, Federico; De Menna, Marta; Realubit, Ronald; Pampou, Sergey; Karan, Charles; Alexandrov, Theodore; Kruithof-de Julio, Marianna; Califano, Andrea; Boulant, Steeve; Alvarez, Mariano 分享 收藏 A phase 1 clinical trial of oral eltanexor in patients with relapsed or refractory multiple myelomaCornell, Robert Frank; Baz, Rachid; Richter, Joshua R.; Rossi, Adriana; Vogl, Dan T.; Chen, Christine; Shustik, Chaim; Alvarez, Mariano J.; Shen, Yao; Unger, T. J.; Ben-Shahar, Osnat; Wang, Hongwei; Baloglu, Erkan; Senapedis, William; Ma, Xiwen; Landesman, Yosef; Bai, Xiang; Bader, Justin; Xu, Hongmei; Marshall, Tracey; Chang, Hua; Walker, Christopher J.; Shah, Jatin; Shacham, Sharon; Kauffman, Michael G.; Hofmeister, Craig C. 分享 收藏 Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow使用多模式集成生物信息学工作流系统阐明肌萎缩侧索硬化模型中的神经元-星形胶质细胞相互作用Mishra, Vartika; Re, Diane B.; Le Verche, Virginia; Alvarez, Mariano J.; Vasciaveo, Alessandro; Jacquier, Arnaud; Doulias, Paschalis-Tomas; Greco, Todd M.; Nizzardo, Monica; Papadimitriou, Dimitra; Nagata, Tetsuya; Rinchetti, Paola; Perez-Torres, Eduardo J.; Politi, Kristin A.; Ikiz, Burcin; Clare, Kevin; Than, Manuel E.; Corti, Stefania; Ischiropoulos, Harry; Lotti, Francesco; Califano, Andrea; Przedborski, Serge 分享 收藏 OncoMatch: Unbiased, quantitative assessment of cancer model fidelity for drug sensitivity and mechanism of action elucidationAlvarez, Mariano J.; Pengrong, Yan; Alpaugh, Mary L.; Bowden, Michaela; Sicinska, Ewa T.; Zhou, Chensheng W.; Karan, Charles; Realubit, Ronald B.; Mundi, Prabhjot S.; Grunn, Adina; Dirk, Jager; Chabot, John A.; Fojo, Antonio T.; Oberstein, Paul E.; Hibshoosh, Hanina; Milsom, Jeffrey W.; Kulke, Matthew H.; Loda, Massimo; Chiosis, Gabriela; Reidy-Lagunes, Diane L.; Califano, Andrea 分享 收藏 Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant stateEcheverria, Gloria V.; Ge, Zhongqi; Seth, Sahil; Zhang, Xiaomei; Jeter-Jones, Sabrina; Zhou, Xinhui; Cai, Shirong; Tu, Yizheng; McCoy, Aaron; Peoples, Michael; Sun, Yuting; Qiu, Huan; Chang, Qing; Bristow, Christopher; Carugo, Alessandro; Shao, Jiansu; Ma, Xiaoyan; Harris, Angela; Mundi, Prabhjot; Lau, Rosanna; Ramamoorthy, Vandhana; Wu, Yun; Alvarez, Mariano J.; Califano, Andrea; Moulder, Stacy L.; Symmans, William F.; Marszalek, Joseph R.; Heffernan, Timothy P.; Chang, Jeffrey T.; Piwnica-Worms, Helen 分享 收藏 Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancerRisom, Tyler; Langer, Ellen M.; Chapman, Margaret P.; Rantala, Juha; Fields, Andrew J.; Boniface, Christopher; Alvarez, Mariano J.; Kendsersky, Nicholas D.; Pelz, Carl R.; Johnson-Camacho, Katherine; Dobrolecki, Lacey E.; Chin, Koei; Aswani, Anil J.; Wang, Nicholas J.; Califano, Andrea; Lewis, Michael T.; Tomlin, Claire J.; Spellman, Paul T.; Adey, Andrew; Gray, Joe W.; Sears, Rosalie C. 分享 收藏 分享 收藏 A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumorsAlvarez, Mariano J.; Subramaniam, Prem S.; Tang, Laura H.; Grunn, Adina; Aburi, Mahalaxmi; Rieckhof, Gabrielle; Komissarova, Elena V.; Hagan, Elizabeth A.; Bodei, Lisa; Clemons, Paul A.; Dela Cruz, Filemon S.; Dhall, Deepti; Diolaiti, Daniel; Fraker, Douglas A.; Ghavami, Afshin; Kaemmerer, Daniel; Karan, Charles; Kidd, Mark; Kim, Kyoung M.; Kim, Hee C.; Kunju, Lakshmi P.; Langel, Ulo; Li, Zhong; Lee, Jeeyun; Li, Hai; LiVolsi, Virginia; Pfragner, Roswitha; Rainey, Allison R.; Realubit, Ronald B.; Remotti, Helen; Regberg, Jakob; Roses, Robert; Rustgi, Anil; Sepulveda, Antonia R.; Serra, Stefano; Shi, Chanjuan; Yuan, Xiaopu; Barberis, Massimo; Bergamaschi, Roberto; Chinnaiyan, Arul M.; Detre, Tony; Ezzat, Shereen; Frilling, Andrea; Hommann, Merten; Jaeger, Dirk; Kim, Michelle K.; Knudsen, Beatrice S.; Kung, Andrew L.; Leahy, Emer; Metz, David C.; Milsom, Jeffrey W.; Park, Young S.; Reidy-Lagunes, Diane; Schreiber, Stuart; Washington, Kay; Wiedenmann, Bertram; Modlin, Irvin; Califano, Andrea 分享 收藏 Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma跨队列分析确定TEAD4-MYCN正反馈回路为高危神经母细胞瘤的核心调控元件Rajbhandari, Presha; Lopez, Gonzalo; Capdevila, Claudia; Salvatori, Beatrice; Yu, Jiyang; Rodriguez-Barrueco, Ruth; Martinez, Daniel; Yarmarkovich, Mark; Weichert-Leahey, Nina; Abraham, Brian J.; Alvarez, Mariano J.; Iyer, Archana; Harenza, Jo Lynne; Oldridge, Derek; De Preter, Katleen; Koster, Jan; Asgharzadeh, Shahab; Seeger, Robert C.; Wei, Jun S.; Khan, Javed; Vandesompele, Jo; Mestdagh, Pieter; Versteeg, Rogier; Look, A. Thomas; Young, Richard A.; Iavarone, Antonio; Lasorella, Anna; Silva, Jose M.; Maris, John M.; Califano, Andrea 分享 收藏 Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithmDing, Hongxu; Douglass, Eugene F., Jr.; Sonabend, Adam M.; Mela, Angeliki; Bose, Sayantan; Gonzalez, Christian; Canoll, Peter D.; Sims, Peter A.; Alvarez, Mariano J.; Califano, Andrea 分享 收藏 An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer MetastasisWalsh, Logan A.; Alvarez, Mariano J.; Sabio, Erich Y.; Reyngold, Marsha; Makarov, Vladimir; Mukherjee, Suranjit; Lee, Ken-Wing; Desrichard, Alexis; Turcan, Sxevin; Dalin, Martin G.; Rajasekhar, Vinagolu K.; Chen, Shuibing; Vahdat, Linda T.; Califano, Andrea; Chan, Timothy A. 分享 收藏 分享 收藏 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
