Joseph Cursons - Publications, H-index & Citations

Joseph Cursons

onko-innate pty., ltd.

23H指数

108论文数

3.0K被引数

收录论文 22

发表时间

Core fucosylation of IL-2RB is required for natural killer cell homeostasis IL-2RB的核心岩藻糖基化对于自然杀伤细胞稳态是必需的。

Cell Reports

IF6.9

2025-08-02

OAAI

Harrison Sudholz; Xiangpeng Meng; Hae-Young Park; Zihan Shen; Iva Nikolic; Joseph Cursons; Ethan D. Goddard-Borger; Iona S. Schuster; Christopher E. Andoniou; Mariapia A. Degli-Esposti; Nichollas E. Scott; Michael Chopin; Jai Rautela; Sebastian Scheer; Nicholas D. Huntington

Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling 通过靶向IL-15R信号增强NK细胞的抗肿瘤免疫

Cancer Cell

IF44.5

2025-06-12

PREAI

Iva Nikolic; Joseph Cursons; Benjamin Shields; Stephane Chappaz; Harrison Sudholz; Xiangpeng Meng; Patrick Constantinescu; Reshma Vijayakumaran; Michael D’Angelo; Momeneh Foroutan; David Ladd; Matthew Veldman; Jason Glab; Tahlia Procter; Hae-Young Park; Julian Contet; Felix Deuss; Kahlia Wong; Yi Sun; Richard Berry; Jai Rautela; Nicholas D. Huntington

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer 发现一种高效，选择性，口服生物利用度的KAT6A/B组蛋白乙酰转移酶抑制剂，对KAT6A-high ER乳腺癌有效

CELL CHEMICAL BIOLOGY

IF7.2

2023-10-01

OAAI

Sharma, Shikhar; Chung, Chi-Yeh; Uryu, Sean; Petrovic, Jelena; Cao, Joan; Rickard, Amanda; Nady, Nataliya; Greasley, Samantha; Johnson, Eric; Brodsky, Oleg; Khan, Showkhin; Wang, Hui; Wang, Zhenxiong; Zhang, Yong; Tsaparikos, Konstantinos; Chen, Lei; Mazurek, Anthony; Lapek, John; Kung, Pei-Pei; Sutton, Scott; Richardson, Paul F.; Greenwald, Eric C.; Yamazaki, Shinji; Jones, Rhys; Maegley, Karen A.; Bingham, Patrick; Lam, Hieu; Stupple, Alexandra E.; Kamal, Aileen; Chueh, Anderly; Cuzzupe, Anthony; Morrow, Benjamin J.; Ren, Bin; Carrasco-Pozo, Catalina; Tan, Chin Wee; Bhuva, Dharmesh D.; Allan, Elizabeth; Surgenor, Elliot; Vaillant, Francois; Pehlivanoglu, Havva; Falk, Hendrik; Whittle, James R.; Newman, Janet; Cursons, Joseph; Doherty, Judy P.; White, Karen L.; Macpherson, Laura; Devlin, Mark; Dennis, Matthew L.; Hattarki, Meghan K.; De Silva, Melanie; Camerino, Michelle A.; Butler, Miriam S.; Dolezal, Olan; Pilling, Patricia; Foitzik, Richard; Stupple, Paul A.; Lagiakos, H. Rachel; Walker, Scott R.; Hediyeh-Zadeh, Soroor; Nuttall, Stewart; Spall, Sukhdeep; Charman, Susan A.; Connor, Theresa; Peat, Thomas S.; Avery, Vicky M.; Bozikis, Ylva E.; Yang, Yuqing; Zhang, Ming; Monahan, Brendon J.; Voss, Anne K.; Street, Ian P.; Dawson, Sarah-Jane; Dawson, Mark A.; Lindeman, Geoffrey J.; Davis, Melissa J.; Visvader, Jane E.; Paul, Thomas A.

Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer 在三阴性乳腺癌中使用CRISPR/dCas9平台的间充质上皮状态的合成表观遗传重编程

ADVANCED SCIENCE

IF14.1

2023-05-22

OAAI

Waryah, Charlene; Cursons, Joseph; Foroutan, Momeneh; Pflueger, Christian; Wang, Edina; Molania, Ramyar; Sorolla, Anabel; Wallis, Christopher; Moses, Colette; Glas, Irina; Magalhaes, Leandro; Thompson, Erik W.; Fearnley, Liam G.; Chaffer, Christine L.; Davis, Melissa; Papenfuss, Anthony T.; Redfern, Andrew; Lister, Ryan; Esteller, Manel; Blancafort, Pilar

Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma

CLINICAL EPIGENETICS

IF4.4

2023-04-29

OAAI

Sgro, Agustin; Cursons, Joseph; Waryah, Charlene; Woodward, Eleanor A.; Foroutan, Momeneh; Lyu, Ruqian; Yeoh, George C. T.; Leedman, Peter J.; Blancafort, Pilar

High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes

GENOME RESEARCH

IF5.5

2022-06-27

OAAI

Muskovic, Walter; Slavich, Eve; Maslen, Ben; Kaczorowski, Dominik C. C.; Cursons, Joseph; Crampin, Edmund; Kavallaris, Maria

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer 癌基因AAMDC将PI3K-AKT-mTOR信号传导与雌激素受体阳性乳腺癌中的代谢重编程联系起来

NATURE COMMUNICATIONS

IF15.7

2021-03-26

OAAI

Golden, Emily; Rashwan, Rabab; Woodward, Eleanor A.; Sgro, Agustin; Wang, Edina; Sorolla, Anabel; Waryah, Charlene; Tie, Wan Jun; Cuyas, Elisabet; Ratajska, Magdalena; Kardas, Iwona; Kozlowski, Piotr; Johnstone, Elizabeth K. M.; See, Heng B.; Duffy, Ciara; Parry, Jeremy; Lagerborg, Kim A.; Czapiewski, Piotr; Menendez, Javier A.; Gorczynski, Adam; Wasag, Bartosz; Pfleger, Kevin D. G.; Curtis, Christina; Lee, Bum-Kyu; Kim, Jonghwan; Cursons, Joseph; Pavlos, Nathan J.; Biernat, Wojciech; Jain, Mohit; Woo, Andrew J.; Redfern, Andrew; Blancafort, Pilar

Stable gene expression for normalisation and single-sample scoring

NUCLEIC ACIDS RESEARCH

IF13.1

2020-09-30

OAAI

Bhuva, Dharmesh D.; Cursons, Joseph; Davis, Melissa J.

The cancer-natural killer cell immunity cycle

NATURE REVIEWS CANCER

IF66.8

2020-06-24

362

PREAI

Huntington, Nicholas D.; Cursons, Joseph; Rautela, Jai

Differential co-expression-based detection of conditional relationships in transcriptional data: comparative analysis and application to breast cancer 基于差异共表达的转录数据条件关系检测: 比较分析及其在乳腺癌中的应用

GENOME BIOLOGY

IF9.4

2019-11-14

OAAI

Bhuva, Dharmesh D.; Cursons, Joseph; Smyth, Gordon K.; Davis, Melissa J.

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

SCIENCE SIGNALING

IF6.6

2019-08-27

OAAI

Rautela, Jai; Dagley, Laura F.; de Oliveira, Carolina C.; Schuster, Iona S.; Hediyeh-Zadeh, Soroor; Delconte, Rebecca B.; Cursons, Joseph; Hennessy, Robert; Hutchinson, Dana S.; Harrison, Craig; Kita, Badia; Vivier, Eric; Webb, Andrew I.; Degli-Esposti, Mariapia A.; Davis, Melissa J.; Huntington, Nicholas D.; Souza-Fonseca-Guimaraes, Fernando

Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA)

NUCLEIC ACIDS RESEARCH

IF13.1

2019-08-02

OAAI

Pillman, Katherine A.; Scheer, Kaitlin G.; Hackett-Jones, Emily; Saunders, Klay; Bert, Andrew G.; Toubia, John; Whitfield, Holly J.; Sapkota, Sunil; Sourdin, Laura; Hoang Pham; Le, Thuc D.; Cursons, Joseph; Davis, Melissa J.; Gregory, Philip A.; Goodall, Gregory J.; Bracken, Cameron P.

A Thermodynamic Framework for Modelling Membrane Transporters

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Pan, Michael; Gawthrop, Peter J.; Tran, Kenneth; Cursons, Joseph; Crampin, Edmund J.

The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy

TRENDS IN IMMUNOLOGY

IF13.9

2019-02-01

215

PREAI

Souza-Fonseca-Guimaraes, Fernando; Cursons, Joseph; Huntington, Nicholas D.

Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT

CELL SYSTEMS

IF7.7

2018-07-01

OAAI

Cursons, Joseph; Pillman, Katherine A.; Scheer, Kaitlin G.; Gregory, Philip A.; Foroutan, Momeneh; Hediyeh-Zadeh, Soroor; Toubia, John; Crampin, Edmund J.; Goodall, Gregory J.; Bracken, Cameron P.; Davis, Melissa J.

A Transcriptional Program for Detecting TGFβ-Induced EMT in Cancer

MOLECULAR CANCER RESEARCH

IF4.7

2017-05-01

OAAI

Foroutan, Momeneh; Cursons, Joseph; Hediyeh-Zadeh, Soroor; Thompson, Erik W.; Davis, Melissa J.

The complexities and caveats of lineage tracing in the mammary gland

BREAST CANCER RESEARCH

IF5.6

2016-11-25

OAAI

Rios, Anne C.; Fu, Nai Yang; Cursons, Joseph; Lindeman, Geoffrey J.; Visvader, Jane E.

Systems analysis identifies miR-29b regulation of invasiveness in melanoma

MOLECULAR CANCER

IF33.9

2016-11-16

OAAI

Andrews, Miles C.; Cursons, Joseph; Hurley, Daniel G.; Anaka, Matthew; Cebon, Jonathan S.; Behren, Andreas; Crampin, Edmund J.

Spatially transformed fluorescence image data for ERK-MAPK and selected proteins within human epidermis

GIGASCIENCE

IF3.9

2015-12-14

OAAI

Cursons, Joseph; Angel, Catherine E.; Hurley, Daniel G.; Print, Cristin G.; Dunbar, P. Rod; Jacobs, Marc D.; Crampin, Edmund J.

Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines

CELL COMMUNICATION AND SIGNALING

IF8.9

2015-05-15

OAAI

Cursons, Joseph; Leuchowius, Karl-Johan; Waltham, Mark; Tomaskovic-Crook, Eva; Foroutan, Momeneh; Bracken, Cameron P.; Redfern, Andrew; Crampin, Edmund J.; Street, Ian; Davis, Melissa J.; Thompson, Erik W.

研究方向