Serwas, Nina K.; Hoeger, Birgit; Ardy, Rico C.; Stulz, Sigrun V.; Sui, Zhenhua; Memaran, Nima; Meeths, Marie; Krolo, Ana; Petronczki, Oezlem Yuece; Pfajfer, Laurene; Hou, Tie Z.; Halliday, Neil; Santos-Valente, Elisangela; Kalinichenko, Artem; Kennedy, Alan; Mace, Emily M.; Mukherjee, Malini; Tesi, Bianca; Schrempf, Anna; Pickl, Winfried F.; Loizou, Joanna I.; Kain, Renate; Bidmon-Fliegenschnee, Bettina; Schickel, Jean-Nicolas; Glauzy, Salome; Huemer, Jakob; Garncarz, Wojciech; Salzer, Elisabeth; Pierides, Iro; Bilic, Ivan; Thiel, Jens; Priftakis, Peter; Banerjee, Pinaki P.; Foerster-Waldl, Elisabeth; Medgyesi, David; Huber, Wolf-Dietrich; Orange, Jordan S.; Meffre, Eric; Sansom, David M.; Bryceson, Yenan T.; Altman, Amnon; Boztug, Kaan

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

NATURE COMMUNICATIONS

IF15.7

2019-07-1558

OAAI

Serwas, Nina K.; Hoeger, Birgit; Ardy, Rico C.; Stulz, Sigrun V.; Sui, Zhenhua; Memaran, Nima; Meeths, Marie; Krolo, Ana; Petronczki, Ozlem Yuce; Pfajfer, Laurene; Hou, Tie Z.; Halliday, Neil; Santos-Valente, Elisangela; Kalinichenko, Artem; Kennedy, Alan; Mace, Emily M.; Mukherjee, Malini; Tesi, Bianca; Schrempf, Anna; Loizou, Joanna I.; Kain, Renate; Bidmon-Fliegenschnee, Bettina; Schickel, Jean-Nicolas; Glauzy, Salome; Huemer, Jakob; Garncarz, Wojciech; Salzer, Elisabeth; Pierides, Iro; Bilic, Ivan; Thiel, Jens; Priftakis, Peter; Banerjee, Pinaki P.; Foerster-Waldl, Elisabeth; Medgyesi, David; Huber, Wolf-Dietrich; Orange, Jordan S.; Meffre, Eric; Sansom, David M.; Bryceson, Yenan T.; Altman, Amnon; Boztug, Kaan

CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells

共刺激分子的CTLA-4-mediated跨胞吞作用主要靶向迁移树突状细胞

SCIENCE IMMUNOLOGY

IF16.3

2019-05-24103

OAAI

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IF11.2

2018-12-01313

OAAI

Schwab, Charlotte; Gabrysch, Annemarie; Olbrich, Peter; Patino, Virginia; Warnatz, Klaus; Wolff, Daniel; Hoshino, Akihiro; Kobayashi, Masao; Imai, Kohsuke; Takagi, Masatoshi; Dybedal, Ingunn; Haddock, Jamanda A.; Sansom, David M.; Lucena, Jose M.; Seidl, Maximilian; Schmitt-Graeff, Annette; Reiser, Veronika; Emmerich, Florian; Frede, Natalie; Bulashevska, Alla; Salzer, Ulrich; Schubert, Desiree; Hayakawa, Seiichi; Okada, Satoshi; Kanariou, Maria; Kucuk, Zeynep Yesim; Chapdelaine, Hugo; Petruzelkova, Lenka; Sumnik, Zdenek; Sediva, Anna; Slatter, Mary; Arkwright, Peter D.; Cant, Andrew; Lorenz, Hanns-Martin; Giese, Thomas; Lougaris, Vassilios; Plebani, Alessandro; Price, Christina; Sullivan, Kathleen E.; Moutschen, Michel; Litzman, Jiri; Freiberger, Tomas; van de Veerdonk, Frank L.; Recher, Mike; Albert, Michael H.; Hauck, Fabian; Seneviratne, Suranjith; Schmid, Jana Pachlopnik; Kolios, Antonios; Unglik, Gary; Klemann, Christian; Speckmann, Carsten; Ehl, Stephan; Leichtner, Alan; Blumberg, Richard; Franke, Andre; Snapper, Scott; Zeissig, Sebastian; Cunningham-Rundles, Charlotte; Giulino-Roth, Lisa; Elemento, Olivier; Dueckers, Gregor; Niehues, Tim; Fronkova, Eva; Kanderova, Veronika; Platt, Craig D.; Chou, Janet; Chatila, Talal A.; Geha, Raif; McDermott, Elizabeth; Bunn, Su; Kurzai, Monika; Schulz, Ansgar; Alsina, Laia; Casals, Ferran; Deya-Martinez, Angela; Hambleton, Sophie; Kanegane, Hirokazu; Tasken, Kjetil; Neth, Olaf; Grimbacher, Bodo

Characterization of CTLA4 Trafficking and Implications for Its Function

BIOPHYSICAL JOURNAL

IF3.1

2018-10-0149

OAAI

Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint

JOURNAL OF AUTOIMMUNITY

IF7

2018-03-0120

OAAI

David M. Sansom

个人简介

教育背景

工作经历

荣誉奖项

研究方向