Eirı́kur Steingrı́msson - Publications, H-index & Citations

Eirı́kur Steingrı́msson

University of Iceland

45H指数

149论文数

9.4K被引数

收录论文 80

发表时间

MICAL2 as a key effector of β-catenin signaling driving melanoma progression and therapeutic resistance MICAL2作为驱动黑色素瘤进展和耐药性的β-连环蛋白信号关键效应器

Cell Death and Differentiation

IF15.4

2026-08-14

PREAI

Pierre Sohier; Jérémy H. Raymond; Zackie Aktary; Nour Zidi; Lara Araktingi; Nisamanee Charoenchon; Céline Pisibon; Sylvie Caberia; Eric Pasmant; Nicolas Macagno; Véronique Delmas; Caroline Gaudy-Marqueste; Eirikur Steingrimsson; Robert Ballotti; Valérie Petit; Lionel Larue

MITF maintains genome stability in nonmelanocyte lineages MITF在非黑色素细胞谱系中维持基因组稳定性

Molecular Oncology

IF4.5

2026-06-10

OAAI

Drifa H. Gudmundsdottir; Adrián López García de Lomana; Thejus B. Venkatesh; Kritika Kirty; Snaevar Sigurdsson; Linda Vidarsdottir; Ramile Dilshat; Erla Sveinbjornsdottir; Snaedis Ragnarsdottir; Daniel H Magnusson; Maria R. Bustos; Eirikur Steingrimsson; Thorkell Gudjonsson; Stefan Sigurdsson

Enhanced IFNy response in dedifferentiated melanoma cells is due to chromatin remodeling as revealed by ATAC-seq 去分化的黑色素瘤细胞中增强的IFNy应答是由于ATAC-seq揭示的染色质重塑所致。

Cell Communication and Signaling

IF8.9

2026-03-28

OAAI

Teitur Sævarsson; Adrián López García de Lomana; Ólafur Sánchez; Siggeir Fannar Brynjólfsson; Eiríkur Steingrímsson; Berglind Ósk Einarsdóttir

Phenotype switching in melanoma cells: MITF regulates the expression of CDH1 through E-boxes in an intronic region 黑色素瘤细胞中的表型转换：MITF通过内含子区域中的E-box调控CDH1的表达

Journal of Investigative Dermatology

IF5.7

2025-11-26

OAAI

Evangeline Breeta Raja David Isac; Sara Sigurbjörnsdóttir; Ramile Dilshat; Robert A. Cornell; Colin Kenny; Eiríkur Steingrímsson

African-ancestry-specific variant IKKβ p.Glu502Lys confers high lupus risk 非洲血统特异性变异IKKβ p.Glu502Lys增加狼疮风险

Nature Genetics

IF29

2025-11-17

OAAI

Gudny Ella Thorlacius; Erna V. Ivarsdottir; Saedis Saevarsdottir; Kristjan H. S. Moore; Sigurjon A. Gudjonsson; Bjarni V. Halldorsson; Hilma Holm; Aslaug Jonasdottir; Frosti Jonsson; Snaedis Kristmundsdottir; Gisli Masson; Olafur T. Magnusson; Gudmundur L. Norddahl; Asmundur Oddsson; Thorunn A. Olafsdottir; Pall I. Olason; Aron Skaftason; Lilja Stefansdottir; Arni Sturluson; Unnur Thorsteinsdottir; Gudmar Thorleifsson; Valentin Y. Walker; Florian Zink; Eirikur Steingrimsson; Daniel F. Gudbjartsson; Ingileif Jonsdottir; Agnar Helgason; Patrick Sulem; Kari Stefansson

Target Genes of MITF in Projection Neurons of the Olfactory Bulb—A Role for MITF in Defining Gene Expression of Middle Tufted Cells 嗅球投射神经元中MITF的目标基因——MITF在定义中间树突细胞基因表达中的作用

European Journal of Neuroscience

IF2.4

2025-11-11

PREAI

Fatich Mechmet; Alba Sabaté San José; Snævar Sigurðsson; Ingvi Gautsson; Eiríkur Steingrímsson; Pétur Henry Petersen

Antagonistic roles for MITF and TFE3 in melanoma plasticity MITF和TFE3在黑色素瘤可塑性中的拮抗作用

CELL REPORTS

IF6.9

2025-04-01

PREAI

Chang, Jeremy; Campbell-Hanson, Katelyn R.; Vanneste, Marion; Bartschat, Nicholas I.; Nagel, Ryan; Arnadottir, Asdis K.; Vu, Hong Nhung; Montgomery, Collin; Yevdash, Julius; Jiang, Jiarui; Bhinu, Ardith; Helverson, Annika; Henry, Michael D.; Steingrimsson, Eirikur; Weigel, Ronald J.; Cornell, Robert A.; Kenny, Colin

Differentiation status determines the effects of IFNγ on the expression of PD-L1 and immunomodulatory genes in melanoma 分化状态决定ifn γ 对黑色素瘤PD-L1和免疫调节基因表达的影响

CELL COMMUNICATION AND SIGNALING

IF8.9

2024-12-31

OAAI

Saevarsson, Teitur; de Lomana, Adrian Lopez Garcia; Sanchez, Olafur; van Esch, Veerle; Ragnarsson, Gunnar Bjarni; Brynjolfsson, Siggeir Fannar; Steingrimsson, Eirikur; Einarsdottir, Berglind osk

Reduction in the olfactory ability in aging Mitf mutant mice without evidence of neurodegeneration

FRONTIERS IN AGING

IF4.3

2024-10-25

OAAI

Mechmet, Fatich; Steingrimsson, Eirikur; Petersen, Petur Henry

Novel mechanisms of MITF regulation identified in a mouse suppressor screen

EMBO REPORTS

IF6.2

2024-08-21

OAAI

Vu, Hong Nhung; Valdimarsson, Matti Mar; Sigurbjoernsdottir, Sara; Bergsteinsdottir, Kristin; Debbache, Julien; Bismuth, Keren; Swing, Deborah A.; Hallsson, Jon H.; Larue, Lionel; Arnheiter, Heinz; Copeland, Neal G.; Jenkins, Nancy A.; Heidarsson, Petur O.; Steingrimsson, Eirikur

ATG7(2) Interacts With Metabolic Proteins and Regulates Central Energy Metabolism

TRAFFIC

IF2.5

2024-04-10

OAAI

Ostacolo, Kevin; de Lomana, Adrian Lopez Garcia; Larat, Clemence; Hjaltalin, Valgerdur; Holm, Kristrun Yr; Hlynsdottir, Sigriour S.; Soucheray, Margaret; Sooman, Linda; Rolfsson, Ottar; Krogan, Nevan J.; Steingrimsson, Eirikur; Swaney, Danielle L.; Ogmundsdottir, Margret H.

Mitf regulates gene expression networks implicated in B cell homeostasis, germinal center responses, and tolerance Mitf调节与b细胞稳态，生发中心反应和耐受性有关的基因表达网络

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-02-20

OAAI

Amarnani, Abhimanyu; Lopez-Ocasio, Maria; Dilshat, Ramile; Anumukonda, Kamala; Davila, Jonathan; Malakhov, Nikita; Huan, Chongmin; Magnusdottir, Erna; Steingrimsson, Eirikur; Roman, Christopher A.

Acetylation reprograms MITF target selectivity and residence time

NATURE COMMUNICATIONS

IF15.7

2023-09-28

OAAI

Louphrasitthiphol, Pakavarin; Loffreda, Alessia; Pogenberg, Vivian; Picaud, Sarah; Schepsky, Alexander; Friedrichsen, Hans; Zeng, Zhiqiang; Lashgari, Anahita; Thomas, Benjamin; Patton, E. Elizabeth; Wilmanns, Matthias; Filippakopoulos, Panagis; Lambert, Jean-Philippe; Steingrimsson, Eirikur; Mazza, Davide; Goding, Colin R.

The microphthalmia-associated transcription factor Mitf interacts with β-catenin to determine target gene expression

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

178

OAAI

Schepsky, Alexander; Bruser, Katja; Gunnarsson, Gunnar J.; Goodall, Jane; Hallsson, Jon H.; Goding, Colin R.; Steingrimsson, Eirikur; Hecht, Andreas

Germline variants of ATG7 in familial cholangiocarcinoma alter autophagy and p62

SCIENTIFIC REPORTS

IF3.9

2022-06-20

OAAI

Greer, Stephanie U.; Chen, Jiamin; Ogmundsdottir, Margret H.; Ayala, Carlos; Lau, Billy T.; Delacruz, Richard Glenn C.; Sandoval, Imelda T.; Kristjansdottir, Sigrun; Jones, David A.; Haslem, Derrick S.; Romero, Robin; Fulde, Gail; Bell, John M.; Jonasson, Jon G.; Steingrimsson, Eirikur; Ji, Hanlee P.; Nadauld, Lincoln D.

TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes

PLOS GENETICS

IF3.7

2022-05-17

OAAI

Kenny, Colin; Dilshat, Ramile; Seberg, Hannah E.; Van Otterloo, Eric; Bonde, Gregory; Helverson, Annika; Franke, Christopher M.; Steingrimsson, Eirikur; Cornell, Robert A.

Hedgehog signalling in bone and osteoarthritis: the role of Smoothened and cholesterol

FEBS JOURNAL

IF4.2

2022-03-27

PREAI

Smith, Abbi Elise; Sigurbjornsdottir, Elin Soley; Steingrimsson, Eirikur; Sigurbjornsdottir, Sara

Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2021-09-01

OAAI

Zhang, Tongwu; Choi, Jiyeon; Dilshat, Ramile; Einarsdottir, Berglind Osk; Kovacs, Michael A.; Xu, Mai; Malasky, Michael; Chowdhury, Salma; Jones, Kristine; Bishop, D. Timothy; Goldstein, Alisa M.; Iles, Mark M.; Landi, Maria Teresa; Law, Matthew H.; Shi, Jianxin; Steingrimsson, Eirikur; Brown, Kevin M.

BRN2 is a non-canonical melanoma tumor-suppressor

NATURE COMMUNICATIONS

IF15.7

2021-06-17

OAAI

Hamm, Michael; Sohier, Pierre; Petit, Valerie; Raymond, Jeremy H.; Delmas, Veronique; Le Coz, Madeleine; Gesbert, Franck; Kenny, Colin; Aktary, Zackie; Pouteaux, Marie; Rambow, Florian; Sarasin, Alain; Charoenchon, Nisamanee; Bellacosa, Alfonso; Sanchez-del-Campo, Luis; Mosteo, Laura; Lauss, Martin; Meijer, Dies; Steingrimsson, Eirikur; Jonsson, Goran B.; Cornell, Robert A.; Davidson, Irwin; Goding, Colin R.; Larue, Lionel

Epigenetic regulation during melanocyte development and homeostasis

EXPERIMENTAL DERMATOLOGY

IF3.1

2021-05-31

OAAI

Dilshat, Ramile; Vu, Hong Nhung; Steingrimsson, Eirikur

研究方向