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M

Mathieu Lupien

university health network

67H指数
449论文数
1.7W被引数
收录论文 118
发表时间
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A chromatin-informed transcriptional regulatory framework to stratify patients and guide therapy selection in triple-negative breast cancer基于染色质的转录调控框架用于三阴性乳腺癌患者的分层和指导治疗选择
errNature Communications
IF15.7
err2026-08-06
err0
errOAAI
errShalini Bahl; Nergiz Dogan-Artun; Julia Nguyen; Hassan Mahmoud; Wail Ba-alawi; Seyed Ali Madani Tonekaboni; Komaldeep Kaur Kang; Meghan McGuire; Chantal Tobin; Jennifer Silvester; Paul Savage; Lucie Cressot; Ankita Nand; Guanqiao Feng; Paul Guilhamon; Arvind Singh Mer; Christopher Arlidge; Mitchell J. Elliott; Morag Park; David W. Cescon; Benjamin Haibe-Kains; Mathieu Lupien
err分享
err收藏
Transposable elements shape stemness in normal and leukemic hematopoiesis转座元件在正常和白血病造血中的形状
errNature Genetics
IF29
err2026-05-04
err0
errOAAI
errGiacomo Grillo; Bettina Nadorp; Aditi Qamra; Bryce Drylie; Amanda Mitchell; Christopher Arlidge; Ankita Nand; Naoya Takayama; Alex Murison; Seyed Ali Madani Tonekaboni; Komaldeep Kaur Kang; Andrea Arruda; Jean C. Y. Wang; Mark D. Minden; Özgen Deniz; Héléna Boutzen; John E. Dick; Mathieu Lupien
err分享
err收藏
Convergent evolution of complex structural variants drives therapy resistance in metastatic prostate cancer复杂结构变异的趋同进化驱动转移性前列腺癌的疗法抗性
errGenome Biology
IF9.4
err2026-04-15
err0
errOAAI
errThaidy Moreno-Rodriguez; Meng Zhang; Arian Lundberg; Raunak Shrestha; Martin Sjöström; Anupama Pasam; Joanna Chan; Lisa Devereux; Adam Foye; Xiaolin Zhu; Alana S. Weinstein; Anna S. Trigos; Alexander W. Wyatt; Joshi J. Alumkal; Eric J. Small; Rahul Aggarwal; Scott M. Dehm; Matthew L. Bootsma; Shuang G. Zhao; Mathieu Lupien; Felix Y. Feng; Shahneen Sandhu; David A. Quigley
err分享
err收藏
A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection1,294血浆无细胞DNA甲基化组和片段组的泛癌纲要，可进行多癌检测
errNature Cancer
IF28.5
err2026-02-19
err0
errOAAI
errYong Zeng; Dor D. Abelman; Althaf Singhawansa; Nicholas Cheng; Yuanchang Fang; Sasha C. Main; Emma Bell; Wenbin Ye; Ping Luo; Samantha L. Wilson; Eric Y. Stutheit-Zhao; Derek Wong; Nadia Znassi; Kui Chen; Suluxan Mohanraj; Enrique Sanz-Garcia; Faiyaz Notta; Anand Ghanekar; Philip Awadalla; Benjamin H. Lok; Michael M. Hoffman; Raymond H. Kim; Gelareh Zadeh; Daniel D. De Carvalho; Scott V. Bratman; Mathieu Lupien; Trevor J. Pugh; Housheng Hansen He
err分享
err收藏
METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancersMETTL3-based表转录组编辑筛选确定癌症中的功能性m6A位点
errNature Cancer
IF28.5
err2026-02-06
err0
PREAI
errXin Xu; Yujuan Wang; Helen Zhu; Magnus Lam; Wenqin Luo; Mona Teng; Yin Liu; Wang Yuan Guo; Aastha Aastha; Xi Xu; Sujun Chen; Xinpei Ci; Shiyan Wang; Yong Zeng; Guanghui Zhu; Thomas Kislinger; Mathieu Lupien; Ming-Sound Tsao; Housheng Hansen He
err分享
err收藏
Clonal evolution and transcriptional plasticity shape metastatic dissemination routes in prostate cancer克隆演化和转录可塑性塑造了前列腺癌的转移播散途径
errNature Communications
IF15.7
err2025-12-23
err0
errOAAI
errMigle Mikutenaite; Evdoxia Karadoulama; Francesco Favero; Alessio Locallo; Francisco German Rodriguez Gonzalez; Daria Kiriy; Tina Keshavarzian; Kira Furlano; Markus Graefen; Robert G. Bristow; Clarissa Gerhäuser; Christoph Plass; Guido Sauter; Ronald Simon; Mathieu Lupien; Sarah Minner; Thorsten Schlomm; Joachim Weischenfeldt
err分享
err收藏
Prostate cancer cells converge to an inflammatory-like state upon metastatic dissemination前列腺癌细胞在发生转移性播散时趋近于一种炎症样状态。
errNature Communications
IF15.7
err2025-12-23
err0
errOAAI
errTina Keshavarzian; Kira Furlano; Giacomo Grillo; Lisanne Mout; Christopher Arlidge; Faizan Hasan; Ankita Nand; Migle Mikutenaite; Evdoxia Karadoulama; Ashish Goyal; Elisabeth L. Pezzuto; Jessica Heilmann; Jakub Sykora; Sarah Minner; Thorsten Schlomm; Guido Sauter; Ronald Simon; Housheng Hansen He; Joachim Weischenfeldt; Christoph Plass; Clarissa Gerhäuser; Mathieu Lupien
err分享
err收藏
Simulating cell-free chromatin using preclinical cancer models for liquid biopsy applications利用临床前癌症模型模拟无细胞染色质，用于液体活检应用
erriScience
IF4.1
err2025-11-22
err0
errOAAI
errSasha C. Main; Steven D. De Michino; Lucas Penny; Aleem Aamir; Tina Keshavarzian; Benjamin H. Lok; Robert Kridel; David W. Cescon; Michael M. Hoffman; Mathieu Lupien; Scott V. Bratman
err分享
err收藏
Epigenomics-guided precision oncology: Chromatin variants in prostate tumor evolution表观基因组学指导的精确肿瘤学: 前列腺肿瘤进化中的染色质变异
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2025-01-23
err0
errOAAI
errFurlano, Kira; Keshavarzian, Tina; Biernath, Nadine; Fendler, Annika; de Santis, Maria; Weischenfeldt, Joachim; Lupien, Mathieu
err分享
err收藏
A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
errCELL CHEMICAL BIOLOGY
IF7.2
err2024-11-01
err2
PREAI
errZhang, KeJing; Wei, Juan; Zhang, SheYu; Fei, Liyan; Guo, Lu; Liu, Xueying; Ji, YiShuai; Chen, WenJun; Ciamponi, Felipe E.; Chen, WeiChang; Li, MengXi; Zhai, Jie; Fu, Ting; Massirer, Katlin B.; Yu, Yang; Lupien, Mathieu; Wei, Yong; Arrowsmith, Cheryl. H.; Wu, Qin; Tan, WeiHong
err分享
err收藏
Epigenomic heterogeneity as a source of tumour evolution表观基因组异质性是肿瘤进化的来源
errNATURE REVIEWS CANCER
IF66.8
err2024-10-16
err1
PREAI
errLaisne, Marthe; Lupien, Mathieu; Vallot, Celine
err分享
err收藏
Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties
errLEUKEMIA
IF13.4
err2024-08-21
err0
errOAAI
errBoutzen, Helena; Murison, Alex; Oriecuia, Alexa; Bansal, Suraj; Arlidge, Christopher; Wang, Jean C. Y.; Lupien, Mathieu; Kaufmann, Kerstin B.; Dick, John E.
err分享
err收藏
An atlas of accessible chromatin in advanced prostate cancer
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errShrestha, Raunak; Chesner, Lisa N.; Zhang, Meng; Zhou, Stanley; Foye, Adam; Lundberg, Arian; Weinstein, Alana S.; Sjostrom, Martin; Zhu, Xiaolin; Moreno-Rodriguez, Thaidy; Li, Haolong; Alumkal, Joshi J.; Aggarwal, Rahul; Small, Eric J.; Lupien, Mathieu; Quigley, David A.; Feng, Felix Y.
err分享
err收藏
Detection of metabolic adaptation in a triple-negative breast cancer animal model with [18F]choline-PET imaging as a surrogate for drug resistance
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2023-12-14
err0
PREAI
errKohan, Andres A.; Lupien, Mathieu; Cescon, David; Deblois, Genevieve; Ventura, Manuela; Metser, Ur; Veit-Haibach, Patrick
err分享
err收藏
Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors
errMOLECULAR CANCER
IF33.9
err2023-11-28
err6
errOAAI
errLlinas-Arias, Pere; Ensenyat-Mendez, Miquel; Iniguez-Munoz, Sandra; Orozco, Javier I. J.; Valdez, Betsy; Salomon, Matthew P.; Matsuba, Chikako; Solivellas-Pieras, Maria; Bedoya-Lopez, Andres F.; Sese, Borja; Mezger, Anja; Ormestad, Mattias; Unzueta, Fernando; Strand, Siri H.; Boiko, Alexander D.; Hwang, E. Shelley; Cortes, Javier; Dinome, Maggie L.; Esteller, Manel; Lupien, Mathieu; Marzese, Diego M.
err分享
err收藏
The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population炎症性肠病中CD4 T细胞的染色质和单细胞转录景观将风险基因座与促炎Th17细胞群联系起来
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-08-03
err7
errOAAI
errMedina, Tiago S.; Murison, Alex; Smith, Michelle; Kinker, Gabriela S.; Chakravarthy, Ankur; Vitiello, Glauco A. F.; Turpin, Williams; Shen, Shu Yi; Yau, Helen L.; Sarmento, Olga F.; Faubion, William; Lupien, Mathieu; Silverberg, Mark S.; Arrowsmith, Cheryl H.; De Carvalho, Daniel D.
err分享
err收藏
Human papillomavirus integration transforms chromatin to drive oncogenesis
errGENOME BIOLOGY
IF9.4
err2023-06-27
err10
errOAAI
errKarimzadeh, Mehran; Arlidge, Christopher; Rostami, Ariana; Lupien, Mathieu; Bratman, Scott V.; Hoffman, Michael M.
err分享
err收藏
Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer
errONCOGENE
IF7.3
err2023-04-05
err7
errOAAI
errCameron, Sarina; Deblois, Genevieve; Hawley, James R.; Qamra, Aditi; Zhou, Stanley; Tonekaboni, Seyed Ali Madani; Murison, Alexander; Van Vliet, Romy; Liu, Juan; Locasale, Jason W.; Lupien, Mathieu
err分享
err收藏
Coactivator Function Defines the Active Estrogen Receptor Alpha Cistrome共激活功能定义了活性雌激素受体 α Cistrome
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err80
errOAAI
errLupien, Mathieu; Eeckhoute, Jerome; Meyer, Clifford A.; Krum, Susan A.; Rhodes, Daniel R.; Liu, X. Shirley; Brown, Myles
err分享
err收藏
Genomic Collaboration of Estrogen Receptor α and Extracellular Signal-Regulated Kinase 2 in Regulating Gene and Proliferation Programs雌激素受体 α 和细胞外信号调节激酶2在调节基因和增殖程序中的基因组协作
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err112
errOAAI
errMadak-Erdogan, Zeynep; Lupien, Mathieu; Stossi, Fabio; Brown, Myles; Katzenellenbogen, Benita S.
err分享
err收藏

研究方向

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