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R

Rachael M. Zemek

Fred Hutchinson Cancer Center
H指数:11
被引数:673

个人简介

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工作经历

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荣誉奖项

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Mesothelioma location influences the tumour microenvironment and immune checkpoint therapy response in preclinical models

间皮瘤的位置影响肿瘤微环境以及在预临床模型中的免疫检查点治疗反应

Scientific Reports
IF3.9
2026-02-250
OAAI
M. Lizeth Orozco Morales; Sally M. Lansley; Wee Loong Chin; Caitlin M. Tilsed; Nicola Principe; Connull Leslie; Breana J. Vitali; Francois X. Rwandamuriye; Emma de Jong; Joel Kidman; Rachael M. Zemek; Catherine A. Rinaldi; Timo Lassmann; Anthony Bosco; Y. C. Gary Lee; Richard A. Lake; Jonathan Chee; W. Joost Lesterhuis
Genital herpes shedding episodes associate with altered spatial organization and activation of mucosal immune cells

生殖器疱疹病毒脱落发作与黏膜免疫细胞的空间组织改变和激活相关联。

JCI Insight
IF6.1
2026-01-091
PRE
Maclean, Finn; Zemek, Rachael M.; Tsegaye, Adino Tesfahun; Graham, Jessica B.; Swarts, Jessica L.; Vick, Sarah C.; Potchen, Nicole B.; Talavera, Irene Cruz; Warrier, Lakshmi; Dubrulle, Julien; Schroeder, Lena K.; Elz, Anna; Sowerby, David; Saito, Ayumi; Thomas, Katherine K.; Mack, Matthias; Schiffer, Joshua T.; McClelland, R. Scott; Jerome, Keith R.; Chohan, Bhavna H.; Ngure, Kenneth; Mugo, Nelly Rwamba; Newell, Evan W.; Lingappa, Jairam R.; Lund, Jennifer M.
Local therapy with combination TLR agonists stimulates systemic anti-tumor immunity and sensitizes tumors to immune checkpoint blockade

联合TLR激动剂的局部治疗刺激全身抗肿瘤免疫并使肿瘤对免疫检查点阻断敏感

ONCOIMMUNOLOGY
IF6.3
2024-08-220
OA
Rwandamuriye, Francois Xavier; Wang, Tao; Zhang, Hanfu; Elaskalani, Omar; Kuster, Jorren; Ye, Xueting; Vitali, Breana; Schreurs, Juliet; Morales, M. Lizeth Orozco; Norret, Marck; Evans, Cameron W.; Zemek, Rachael M.; Iyer, K. Swaminathan; Lesterhuis, W. Joost; Wylie, Ben
Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes
ONCOIMMUNOLOGY
IF6.3
2024-04-262
OA
Kidman, Joel; Zemek, Rachael M.; Sidhom, John-William; Correa, Debora; Principe, Nicola; Sheikh, Fezaan; Fear, Vanessa S.; Forbes, Catherine A.; Chopra, Abha; Boon, Louis; Zaitouny, Ayham; de Jong, Emma; Holt, Robert A.; Jones, Matt; Millward, Michael J.; Lassmann, Timo; Forrest, Alistair R. R.; Nowak, Anna K.; Watson, Mark; Lake, Richard A.; Lesterhuis, W. Joost; Chee, Jonathan
A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence

手术优化的术中释放poly(I:C) 的水凝胶可预防癌症复发

CELL REPORTS MEDICINE
IF10.6
2023-07-0112
OAAI
Rwandamuriye, Francois Xavier; Evans, Cameron W.; Wylie, Ben; Norret, Marck; Vitali, Breana; Ho, Diwei; Nguyen, Dat; Roper, Ellise A.; Wang, Tao; Hepburn, Matt S.; Sanderson, Rowan W.; Pfirrmann, Maren; Fear, Vanessa S.; Forbes, Catherine A.; Wyatt, Ken; Ryan, Anne L.; Johns, Terrance G.; Phillips, Marianne B.; Hodder, Rupert; Leslie, Connull; Kennedy, Brendan F.; Zemek, Rachael M.; Iyer, Killugudi Swaminathan; Lesterhuis, Willem Joost
Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy

肿瘤浸润效应记忆抗原特异性CD8 T细胞预测对免疫检查点治疗的反应

FRONTIERS IN IMMUNOLOGY
IF5.9
2020-11-1249
OAAI
Principe, Nicola; Kidman, Joel; Goh, Siting; Tilsed, Caitlin M.; Fisher, Scott A.; Fear, Vanessa S.; Forbes, Catherine A.; Zemek, Rachael M.; Chopra, Abha; Watson, Mark; Dick, Ian M.; Boon, Louis; Holt, Robert A.; Lake, Richard A.; Nowak, Anna K.; Lesterhuis, Willem Joost; McDonnell, Alison M.; Chee, Jonathan
Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2019-07-17163
OAAI
Zemek, Rachael M.; De Jong, Emma; Chin, Wee Loong; Schuster, Iona S.; Fear, Vanessa S.; Casey, Thomas H.; Forbes, Cath; Dart, Sarah J.; Leslie, Connull; Zaitouny, Ayham; Small, Michael; Boon, Louis; Forrest, Alistair R. R.; Muiri, Daithi O.; Degli-Esposti, Mariapia A.; Millward, Michael J.; Nowak, Anna K.; Lassmann, Timo; Bosco, Anthony; Lake, Richard A.; Lesterhuis, W. Joost

研究方向

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W
W. Joost Lesterhuis
H 指数:44论文数:174被引数:8,998
A
Anna K. Nowak
H 指数:87论文数:648被引数:3.0万
R
Richard Lake
H 指数:48论文数:269被引数:1.1万
V
Vanessa S. Fear
H 指数:19论文数:62被引数:1,176
M
Michael Millward
H 指数:61论文数:456被引数:1.6万
T
Timo Lassmann
H 指数:58论文数:273被引数:3.6万
C
Caitlin M. Tilsed
H 指数:10论文数:21被引数:499
W
Wee Loong Chin
H 指数:9论文数:21被引数:450
L
Louis Boon
H 指数:88论文数:696被引数:2.7万
E
Emma de Jong
H 指数:18论文数:55被引数:1,129