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M

Michael B. Brenner

Brigham and Women's Hospital and Harvard Medical School
H指数:120
被引数:6.3万

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Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases

RA和其他自身免疫性关节炎疾病中人体组织中的功能和功能失调的T调节细胞状态

Nature Immunology
IF27.6
2026-06-160
PRE
Byunghee Koh; Shani T. Gal Oz; Ryota Sato; Hung N. Nguyen; Garrett Dunlap; Christopher Mahony; Chrissy Bolton; Lucy R. Wedderburn; Adam P. Croft; Laura Donlin; Melanie H. Smith; Soumya Raychaudhuri; Ilya Korsunsky; Deepak A. Rao; Michael B. Brenner
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis

成纤维细胞tgf β 信号传导的空间模式是类风湿关节炎治疗抵抗的基础

Nature Immunology
IF27.6
2026-01-150
OAAI
Kartik Bhamidipati; Alexa B. R. McIntyre; Shideh Kazerounian; Gao Ce; Soon W. Wong; Miles Tran; Sean A. Prell; Rachel Lau; Vikram Khedgikar; Christopher Altmann; Annabelle Small; Roopa Madhu; Sonia R. Presti; Ksenia S. Anufrieva; Philip E. Blazar; Jeffrey K. Lange; Jennifer A. Seifert; Larry W. Moreland; Adam P. Croft; Melanie H. Smith; Laura T. Donlin; Myles J. Lewis; Anna H. Jonsson; Costantino Pitzalis; Ranjeny Thomas; Ellen M. Gravallese; Michael B. Brenner; Ilya Korsunsky; Mihir D. Wechalekar; Kevin Wei
Author Correction: Distinct fibroblast subsets drive inflammation and damage in arthritis

作者更正：不同的成纤维细胞亚群驱动关节炎中的炎症和损伤

Nature
IF48.5
2025-12-120
OAAI
Adam P. Croft; Joana Campos; Kathrin Jansen; Jason D. Turner; Jennifer Marshall; Moustafa Attar; Loriane Savary; Corinna Wehmeyer; Amy J. Naylor; Samuel Kemble; Jenefa Begum; Kerstin Dürholz; Harris Perlman; Francesca Barone; Helen M. McGettrick; Douglas T. Fearon; Kevin Wei; Soumya Raychaudhuri; Ilya Korsunsky; Michael B. Brenner; Mark Coles; Stephen N. Sansom; Andrew Filer; Christopher D. Buckley
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease

炎症性肠病中抗肿瘤坏死因子治疗的纵向单细胞图谱

NATURE IMMUNOLOGY
IF27.6
2024-10-220
OAAI
Thomas, Tom; Friedrich, Matthias; Rich-Griffin, Charlotte; Pohin, Mathilde; Agarwal, Devika; Pakpoor, Julia; Lee, Carl; Tandon, Ruchi; Rendek, Aniko; Aschenbrenner, Dominik; Jainarayanan, Ashwin; Voda, Alexandru; Siu, Jacqueline H. Y.; Sanches-Peres, Raphael; Nee, Eloise; Sathananthan, Dharshan; Kotliar, Dylan; Todd, Peter; Kiourlappou, Maria; Gartner, Lisa; Ilott, Nicholas; Issa, Fadi; Hester, Joanna; Turner, Jason; Nayar, Saba; Mackerodt, Jonas; Zhang, Fan; Jonsson, Anna; Brenner, Michael; Raychaudhuri, Soumya; Kulicke, Ruth; Ramsdell, Danielle; Stransky, Nicolas; Pagliarini, Ray; Bielecki, Piotr; Spies, Noah; Marsden, Brian; Taylor, Stephen; Wagner, Allon; Klenerman, Paul; Walsh, Alissa; Coles, Mark; Jostins-Dean, Luke; Powrie, Fiona M.; Filer, Andrew; Travis, Simon; Uhlig, Holm H.; Dendrou, Calliope A.; Buckley, Christopher D.
Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
Nature
IF48.5
2024-07-100
PRE
Calvin Law; Vanessa Sue Wacleche; Ye Cao; Arundhati Pillai; John Sowerby; Brandon Hancock; Alice Horisberger; Sabrina Bracero; Viktoriya Skidanova; Zhihan Li; Ifeoluwakiisi Adejoorin; Eilish Dillon; Isaac J. Benque; Diana Pena Nunez; Daimon P. Simmons; Joshua Keegan; Lin Chen; Tina Baker; Phillip Z. Brohawn; Hussein Al-Mossawi; Ling-Yang Hao; Brian Jones; Navin Rao; Yujie Qu; Stephen E. Alves; A. Helena Jonsson; Katharina S. Shaw; Ruth Ann Vleugels; Elena Massarotti; Karen H. Costenbader; Michael B. Brenner; James A. Lederer; Judd F. Hultquist; Jaehyuk Choi; Deepak A. Rao
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
NATURE GENETICS
IF31.8
2023-11-305
OA
Kang, Joyce B.; Shen, Amber Z.; Gurajala, Saisriram; Nathan, Aparna; Rumker, Laurie; Aguiar, Vitor R. C.; Valencia, Cristian; Lagattuta, Kaitlyn A.; Zhang, Fan; Jonsson, Anna Helena; Yazar, Seyhan; Alquicira-Hernandez, Jose; Khalili, Hamed; Ananthakrishnan, Ashwin N.; Jagadeesh, Karthik; Dey, Kushal; Albrecht, Jennifer; Apruzzese, William; Banda, Nirmal; Barnas, Jennifer L.; Bathon, Joan M.; Ben-Artzi, Ami; Boyce, Brendan F.; Boyle, David L.; Bridges, S. Louis; Bykerk, Vivian P.; Campbell, Debbie; Ceponis, Arnold; Cordle, Andrew; Deane, Kevin D.; Firestein, Gary S.; James, Judith A.; Weinand, Kathryn; Xavier, Ramnik J.; Rao, Deepak A.; Brenner, Michael B.; Gutierrez-Arcelus, Maria; Luo, Yang; Sakaue, Saori; Raychaudhuri, Soumya
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
Nature
IF48.5
2023-11-080
OAAI
Fan Zhang; Anna Helena Jonsson; Aparna Nathan; Nghia Millard; Michelle Curtis; Qian Xiao; Maria Gutierrez-Arcelus; William Apruzzese; Gerald F. M. Watts; Dana Weisenfeld; Saba Nayar; Javier Rangel-Moreno; Nida Meednu; Kathryne E. Marks; Ian Mantel; Joyce B. Kang; Laurie Rumker; Joseph Mears; Kamil Slowikowski; Kathryn Weinand; Dana E. Orange; Laura Geraldino-Pardilla; Kevin D. Deane; Darren Tabechian; Arnoldas Ceponis; Gary S. Firestein; Mark Maybury; Ilfita Sahbudin; Ami Ben-Artzi; Arthur M. Mandelin; Alessandra Nerviani; Myles J. Lewis; Felice Rivellese; Costantino Pitzalis; Laura B. Hughes; Diane Horowitz; Edward DiCarlo; Ellen M. Gravallese; Brendan F. Boyce; Larry W. Moreland; Susan M. Goodman; Harris Perlman; V. Michael Holers; Katherine P. Liao; Andrew Filer; Vivian P. Bykerk; Kevin Wei; Deepak A. Rao; Laura T. Donlin; Jennifer H. Anolik; Michael B. Brenner; Soumya Raychaudhuri
Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis
SCIENCE IMMUNOLOGY
IF16.3
2023-07-2813
OA
Wang, Runci; Singaraju, Anvita; Marks, Kathryne E.; Shakib, Lorien; Dunlap, Garrett; Adejoorin, Ifeoluwakiisi; Greisen, Stinne R.; Chen, Lin; Tirpack, Aidan K.; Aude, Carlos; Fein, Miriam R.; Todd, Derrick J.; MacFarlane, Lindsey; Goodman, Susan M.; DiCarlo, Edward F.; Massarotti, Elena M.; Sparks, Jeffrey A.; Jonsson, A. Helena; Brenner, Michael B.; Postow, Michael A.; Chan, Karmela K.; Bass, Anne R.; Donlin, Laura T.; Rao, Deepak A.
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases

跨组织，单细胞基质图谱可确定四种慢性炎症性疾病中共有的病理成纤维细胞表型

MED
IF11.8
2022-07-0194
OA
Korsunsky, Ilya; Wei, Kevin; Pohin, Mathilde; Kim, Edy Y.; Barone, Francesca; Major, Triin; Taylor, Emily; Ravindran, Rahul; Kemble, Samuel; Watts, Gerald F. M.; Jonsson, A. Helena; Jeong, Yunju; Athar, Humra; Windell, Dylan; Kang, Joyce B.; Friedrich, Matthias; Turner, Jason; Nayar, Saba; Fisher, Benjamin A.; Raza, Karim; Marshall, Jennifer L.; Croft, Adam P.; Tamura, Tomoyoshi; Sholl, Lynette M.; Vivero, Marina; Rosas, Ivan O.; Bowman, Simon J.; Coles, Mark; Frei, Andreas P.; Lassen, Kara; Filer, Andrew; Powrie, Fiona; Buckley, Christopher D.; Brenner, Michael B.; Raychaudhuri, Soumya
IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

IL-1-driven基质-中性粒细胞相互作用定义了对治疗无反应的炎症性肠病患者的子集

NATURE MEDICINE
IF50
2021-10-21146
OAAI
Friedrich, Matthias; Pohin, Mathilde; Jackson, Matthew A.; Korsunsky, Ilya; Bullers, Samuel J.; Rue-Albrecht, Kevin; Christoforidou, Zoe; Sathananthan, Dharshan; Thomas, Tom; Ravindran, Rahul; Tandon, Ruchi; Peres, Raphael Sanches; Sharpe, Hannah; Wei, Kevin; Watts, Gerald F. M.; Mann, Elizabeth H.; Geremia, Alessandra; Attar, Moustafa; Barone, Francesca; Barone, Francesca; Brenner, Michael; Buckley, Christopher D.; Coles, Mark; Frei, Andreas P.; Lassen, Kara G.; Powrie, Fiona M.; McCuaig, Sarah; Thomas, Lloyd; Collantes, Elena; Uhlig, Holm H.; Sansom, Stephen N.; Easton, Alistair; Raychaudhuri, Soumya; Travis, Simon P.; Powrie, Fiona M.
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

在胸腺中建立的不同代谢程序控制肿瘤微环境中 γ δ T细胞亚群的效应子功能

NATURE IMMUNOLOGY
IF27.6
2021-01-18125
OAAI
Lopes, Noella; McIntyre, Claire; Martin, Stefania; Raverdeau, Mathilde; Sumaria, Nital; Kohlgruber, Ayano C.; Fiala, Gina J.; Agudelo, Leandro Z.; Dyck, Lydia; Kane, Harry; Douglas, Aaron; Cunningham, Stephen; Prendeville, Hannah; Loftus, Roisin; Carmody, Colleen; Pierre, Philippe; Kellis, Manolis; Brenner, Michael; Arguello, Rafael J.; Silva-Santos, Bruno; Pennington, Daniel J.; Lynch, Lydia
Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal
SCIENCE ADVANCES
IF12.5
2020-06-2646
OAAI
Svensson, Mattias N. D.; Zoccheddu, Martina; Yang, Shen; Nygaard, Gyrid; Secchi, Christian; Doody, Karen M.; Slowikowski, Kamil; Mizoguchi, Fumitaka; Humby, Frances; Hands, Rebecca; SanteIli, Eugenio; Sacchetti, Cristiano; Wakabayashi, Kuninobu; Wu, Dennis J.; Barback, Christopher; Ai, Rizi; Wang, Wei; Sims, Gary P.; Mydel, Piotr; Kasama, Tsuyoshi; Boyle, David L.; Galimi, Francesco; Vera, David; Tremblay, Michel L.; Raychaudhuri, Soumya; Brenner, Michael B.; Firestein, Gary S.; Pitzalis, Costantino; Ekwall, Anna-Karin H.; Stanford, Stephanie; Bottini, Nunzio

研究方向

暂未获取到该数据
S
Soumya Raychaudhuri
H 指数:119论文数:563被引数:8.9万
M
Masahiko Sugita
H 指数:39论文数:154被引数:5,583
G
Gurdyal S. Besra
H 指数:113论文数:676被引数:4.2万
G
Gerald F. Watts
H 指数:124论文数:1,444被引数:7.1万
S
Steven A. Porcelli
H 指数:96论文数:375被引数:3.0万
D
Deepak A. Rao
H 指数:48论文数:225被引数:1.1万
K
Kevin Wei
H 指数:32论文数:111被引数:1.8万
K
Kamil Slowikowski
H 指数:38论文数:110被引数:2.1万
L
Lydia Lynch
H 指数:46论文数:137被引数:8,355
A
A. Helena Jonsson
H 指数:30论文数:84被引数:7,792