Pogorelov, Dimitrii; Bode, Sebastian Felix Nepomuk; He, Xin; Ramiro-Garcia, Javier; Hedin, Fanny; Ammerlaan, Wim; Konstantinou, Maria; Capelle, Christophe M.; Zeng, Ni; Poli, Aurelie; Domingues, Olivia; Montamat, Guillem; Hunewald, Oliver; Cire, Severine; Baron, Alexandre; Longworth, Joseph; Demczuk, Agnieszka; Bazon, Murilo Luiz; Casper, Ingrid; Klimek, Ludger; Neuberger-Castillo, Lorie; Revets, Dominique; Guyonnet, Lea; Delhalle, Sylvie; Zimmer, Jacques; Benes, Vladimir; Codreanu-Morel, Francoise; Lehners-Weber, Christiane; Weets, Ilse; Alper, Pinar; Brenner, Dirk; Gutermuth, Jan; Guerin, Coralie; Morisset, Martine; Hentges, Francois; Schneider, Reinhard; Shamji, Mohamed H.; Betsou, Fay; Wilmes, Paul; Glaab, Enrico; Cosma, Antonio; Goncalves, Jorge; Hefeng, Feng Q.; Ollert, Markus

A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

CELL METABOLISM

IF30.9

2024-08-012

OAAI

Bonetti, Lynn; Horkova, Veronika; Grusdat, Melanie; Longworth, Joseph; Guerra, Luana; Kurniawan, Henry; Franchina, Davide G.; Soriano-Baguet, Leticia; Binsfeld, Carole; Verschueren, Charlene; Spath, Sabine; Ewen, Anouk; Koncina, Eric; Gerardy, Jean-Jacques; Kobayashi, Takumi; Dostert, Catherine; Farinelle, Sophie; Harm, Janika; Fan, Yu-Tong; Chen, Ying; Harris, Isaac S.; Lang, Philipp A.; Vasiliou, Vasilis; Waisman, Ari; Letellier, Elisabeth; Becher, Burkhard; Mittelbronn, Michel; Brenner, Dirk

Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression

NATURE COMMUNICATIONS

IF15.7

2024-07-211

OAAI

Asantewaa, Gloria; Tuttle, Emily T.; Ward, Nathan P.; Kang, Yun Pyo; Kim, Yumi; Kavanagh, Madeline E.; Girnius, Nomeda; Chen, Ying; Rodriguez, Katherine; Hecht, Fabio; Zocchi, Marco; Smorodintsev-Schiller, Leonid; Scales, TashJae Q.; Taylor, Kira; Alimohammadi, Fatemeh; Duncan, Renae P.; Sechrist, Zachary R.; Agostini-Vulaj, Diana; Schafer, Xenia L.; Chang, Hayley; Smith, Zachary R.; O'Connor, Thomas N.; Whelan, Sarah; Selfors, Laura M.; Crowdis, Jett; Gray, G. Kenneth; Bronson, Roderick T.; Brenner, Dirk; Rufini, Alessandro; Dirksen, Robert T.; Hezel, Aram F.; Huber, Aaron R.; Munger, Joshua; Cravatt, Benjamin F.; Vasiliou, Vasilis; Cole, Calvin L.; DeNicola, Gina M.; Harris, Isaac S.

Adipose Treg cells in charge of metabolism

NATURE IMMUNOLOGY

IF27.6

2024-02-141

PRE

PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma

NATURE CANCER

IF28.5

2023-09-1811

OAAI

Wartewig, Tim; Daniels, Jay; Schulz, Miriam; Hameister, Erik; Joshi, Abhinav; Park, Joonhee; Morrish, Emma; Venkatasubramani, Anuroop V.; Cernilogar, Filippo M.; van Heijster, Frits H. A.; Hundshammer, Christian; Schneider, Heike; Konstantinidis, Filippos; Gabler, Judith V.; Klement, Christine; Kurniawan, Henry; Law, Calvin; Lee, Yujin; Choi, Sara; Guitart, Joan; Forne, Ignasi; Giustinani, Jerome; Mueschen, Markus; Jain, Salvia; Weinstock, David M.; Rad, Roland; Ortonne, Nicolas; Schilling, Franz; Schotta, Gunnar; Imhof, Axel; Brenner, Dirk; Choi, Jaehyuk; Ruland, Juergen

Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report

肥胖和癌症十字路口的免疫代谢-Keystone专题讨论会报告

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

IF4.8

2023-03-242

PRE

Cable, Jennifer; Rathmell, Jeffrey C.; Pearce, Erika L.; Ho, Ping-Chih; Haigis, Marcia C.; Mamedov, Murad R.; Wu, Meng-Ju; Kaech, Susan M.; Lynch, Lydia; Febbraio, Mark A.; Bapat, Sagar P.; Hong, Hanna S.; Zou, Weiping; Belkaid, Yasmine; Sullivan, Zuri A.; Keller, Andrea; Wculek, Stefanie K.; Green, Douglas R.; Postic, Catherine; Amit, Ido; Benitah, Salvador Aznar; Jones, Russell G.; Reina-Campos, Miguel; Torres, Santiago Valle; Beyaz, Semir; Brennan, Donal; O'Neill, Luke A. J.; Perry, Rachel J.; Brenner, Dirk

Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions

CELL REPORTS

IF6.9

2023-03-0114

OAAI

Soriano-Baguet, Leticia; Grusdat, Melanie; Kurniawan, Henry; Benzarti, Mohaned; Binsfeld, Carole; Ewen, Anouk; Longworth, Joseph; Bonetti, Lynn; Guerra, Luana; Franchina, Davide G.; Kobayashi, Takumi; Horkova, Veronika; Verschueren, Charlene; Helgueta, Sergio; Gerard, Deborah; More, Tushar H.; Henne, Antonia; Dostert, Catherine; Farinelle, Sophie; Lesur, Antoine; Gerardy, Jean-Jacques; Jager, Christian; Mittelbronn, Michel; Sinkkonen, Lasse; Hiller, Karsten; Meiser, Johannes; Brenner, Dirk

Metabolism and epigenetics at the heart of T cell function

TRENDS IN IMMUNOLOGY

IF13.9

2023-03-0130

OAAI

Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs

CELL METABOLISM

IF30.9

2023-02-0130

OAAI

Corte-Real, Beatriz F.; Hamad, Ibrahim; Hornero, Rebeca Arroyo; Geisberger, Sabrina; Roels, Joris; Van Zeebroeck, Lauren; Dyczko, Aleksandra; van Gisbergen, Marike W.; Kurniawan, Henry; Wagner, Allon; Yoset, Nir; Weiss, Susanne N. Y.; Schmetterer, Klaus G.; Schroeder, Agnes; Krampert, Luka; Haase, Stefanie; Bartolomaeus, Hendrik; Hellings, Niels; Saeys, Yvan; Dubois, Ludwig J.; Brenner, Dirk; Kempa, Stefan; Hafler, David A.; Stegbauer, Johannes; Linker, Ralf A.; Jantsch, Jonathan; Mueller, Dominik N.; Kleinewietfeld, Markus

Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages

NATURE METABOLISM

IF20.8

2022-06-0251

PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing

NATURE METABOLISM

IF20.8

2022-05-2625

Danileviciute, Egle; Zeng, Ni; Capelle, Christophe M.; Paczia, Nicole; Gillespie, Mark A.; Kurniawan, Henry; Benzarti, Mohaned; Merz, Myriam P.; Coowar, Djalil; Fritah, Sabrina; Weisenhorn, Daniela Maria Vogt; Giro, Gemma Gomez; Grusdat, Melanie; Baron, Alexandre; Guerin, Coralie; Franchina, Davide G.; Leonard, Cathy; Domingues, Olivia; Delhalle, Sylvie; Wurst, Wolfgang; Turner, Jonathan D.; Schwamborn, Jens Christian; Meiser, Johannes; Krueger, Rejko; Ranish, Jeff; Brenner, Dirk; Linster, Carole L.; Balling, Rudi; Ollert, Markus; Hefeng, Feng Q.

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis

NATURE COMMUNICATIONS

IF15.7

2022-05-1622

OAAI

A FAsT contribution: Adipocytes rewire their metabolism to acquire immune functions

CELL METABOLISM

IF30.9

2022-05-011

OAAI

Dirk Brenner

个人简介

教育背景

工作经历

荣誉奖项

研究方向