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I

Isaac S. Harris

university of rochester medical center
H指数:38
被引数:2.2万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Biomarker-guided responses in patient-derived organoids predict effective therapies in breast cancer

患者来源类器官中的生物标志物指导反应可预测乳腺癌的有效疗法

Cell Reports Medicine
IF10.6
2026-08-060
OAAI
Tam Binh V. Bui; Denise M. Wolf; Michael C. Bruck; Kaitlin Moore; Jessica Lien; Sarah D.W. Choi; Shruti Warhadpande; Amirabbas Parizadeh; Deborah Dillon; Beth Overmoyer; Filipa Lynce; Lamorna Brown-Swigart; Gillian L. Hirst; Christina Yau; Isaac J. Nijman; Boudewijn M.T. Burgering; Isaac S. Harris; Laura J. Esserman; Laura J. van ‘t Veer; Jennifer M. Rosenbluth
Catabolism of extracellular glutathione supplies cysteine to support tumours

细胞外谷胱甘肽的分解代谢提供半胱氨酸以支持肿瘤

Nature
IF48.5
2026-03-180
OAAI
Fabio Hecht; Marco Zocchi; Emily T. Tuttle; Nathan P. Ward; Fatemeh Alimohammadi; Amal Afzal Khan; Veronica C. Gomes; Bradley Smith; Jennifer J. Twardowski; Bradley N. Mills; Kevin A. Welle; Sina Ghaemmaghami; Zhuoran Zhou; Yuhan Gan; Yun Pyo Kang; Juliana Cazarin; Zamira G. Soares; Mete Emir Ozgurses; Huiping Zhao; Colin Sheehan; Guillaume Cognet; Lila D. Munger; Dhvani Trivedi; Gloria Asantewaa; Sara K. Blick-Nitko; Jason J. Zoeller; Ying Chen; Vasilis Vasiliou; Bradley M. Turner; Stephano S. Mello; Brian J. Altman; Alexander Muir; Jonathan L. Coloff; Joshua Munger; Gina M. DeNicola; Isaac S. Harris
Anisotropic Ferroelectricity in Polar Vortices
ADVANCED MATERIALS
IF26.8
2024-11-070
PRE
Behera, Piush; Ross, Aiden M.; Shanker, Nirmaan; Meisenheimer, Peter; Manna, Mahir; Lin, Ching-Che; Hsu, Shang-Lin; Harris, Isaac; Kavle, Pravin; Husain, Sajid; Ojha, Shashank K.; Das, Sujit; Raja, Archana; Martin, Lane W.; Susarla, Sandhya; Salahuddin, Sayeef; Chen, Long-Qing; Ramesh, Ramamoorthy
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
DEVELOPMENTAL CELL
IF8.7
2024-08-011
OA
Do, Brian T.; Hsu, Peggy P.; Vermeulen, Sidney Y.; Wang, Zhishan; Hirz, Taghreed; Abbott, Keene L.; Aziz, Najihah; Replogle, Joseph M.; Bjelosevic, Stefan; Paolino, Jonathan; Nelson, Samantha A.; Block, Samuel; Darnell, Alicia M.; Ferreira, Raphael; Zhang, Hanyu; Milosevic, Jelena; Schmidt, Daniel R.; Chidley, Christopher; Harris, Isaac S.; Weissman, Jonathan S.; Pikman, Yana; Stegmaier, Kimberly; Cheloufi, Sihem; Su, Xiaofeng A.; Sykes, David B.; Vander Heiden, Matthew G.
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
CELL METABOLISM
IF30.9
2024-08-012
OAAI
Bonetti, Lynn; Horkova, Veronika; Grusdat, Melanie; Longworth, Joseph; Guerra, Luana; Kurniawan, Henry; Franchina, Davide G.; Soriano-Baguet, Leticia; Binsfeld, Carole; Verschueren, Charlene; Spath, Sabine; Ewen, Anouk; Koncina, Eric; Gerardy, Jean-Jacques; Kobayashi, Takumi; Dostert, Catherine; Farinelle, Sophie; Harm, Janika; Fan, Yu-Tong; Chen, Ying; Harris, Isaac S.; Lang, Philipp A.; Vasiliou, Vasilis; Waisman, Ari; Letellier, Elisabeth; Becher, Burkhard; Mittelbronn, Michel; Brenner, Dirk
Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression
NATURE COMMUNICATIONS
IF15.7
2024-07-211
OAAI
Asantewaa, Gloria; Tuttle, Emily T.; Ward, Nathan P.; Kang, Yun Pyo; Kim, Yumi; Kavanagh, Madeline E.; Girnius, Nomeda; Chen, Ying; Rodriguez, Katherine; Hecht, Fabio; Zocchi, Marco; Smorodintsev-Schiller, Leonid; Scales, TashJae Q.; Taylor, Kira; Alimohammadi, Fatemeh; Duncan, Renae P.; Sechrist, Zachary R.; Agostini-Vulaj, Diana; Schafer, Xenia L.; Chang, Hayley; Smith, Zachary R.; O'Connor, Thomas N.; Whelan, Sarah; Selfors, Laura M.; Crowdis, Jett; Gray, G. Kenneth; Bronson, Roderick T.; Brenner, Dirk; Rufini, Alessandro; Dirksen, Robert T.; Hezel, Aram F.; Huber, Aaron R.; Munger, Joshua; Cravatt, Benjamin F.; Vasiliou, Vasilis; Cole, Calvin L.; DeNicola, Gina M.; Harris, Isaac S.
Metabolic modulation of mitochondrial mass during CD4+T cell activation
CELL CHEMICAL BIOLOGY
IF7.2
2023-09-012
OAAI
Kurmi, Kiran; Liang, Dan; van de Ven, Robert; Georgiev, Peter; Gassaway, Brandon Mark; Han, Seongjun; Notarangelo, Giulia; Harris, Isaac S.; Yao, Cong-Hui; Park, Joon Seok; Hu, Song-Hua; Peng, Jingyu; Drijvers, Jefte M.; Boswell, Sarah; Sokolov, Artem; Dougan, Stephanie K.; Sorger, Peter K.; Gygi, Steven P.; Sharpe, Arlene H.; Haigis, Marcia C.
An Organoid Model System to Study Resistance Mechanisms, Predictive Biomarkers, and New Strategies to Overcome Therapeutic Resistance in Early-Stage Triple-Negative Breast Cancer
CANCER RESEARCH
IF16.6
2023-03-011
PRE
Bui, Tam Binh V.; Wolf, Denise M.; Moore, Kaitlin; Harris, Isaac S.; Phadatare, Pravin; Yau, Christina; Swigart, Lamorna A. Brown; Esserman, Laura J.; Coppe, Jean-Philippe; Wulfkuhle, Julia; Petricoin, Emanuel F.; Campbell, Michael; Selfors, Laura M.; Dillon, Deborah A.; Overmoyer, Beth; Lynce, Filipa; Van 't Veer, Laura; Rosenbluth, Jennifer

研究方向

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T
Tak W. Mak
H 指数:181论文数:1,561被引数:12.9万
G
Gina M. DeNicola
H 指数:41论文数:314被引数:1.4万
J
Joan S. Brugge
H 指数:126论文数:598被引数:5.5万
D
Dirk Brenner
H 指数:47论文数:124被引数:1.0万
J
Jennifer E. Endress
H 指数:11论文数:23被引数:1,348
G
Gloria Asantewaa
H 指数:4论文数:16被引数:248
E
Emily Tuttle
H 指数:9论文数:35被引数:546
V
Vasilis Vasiliou
H 指数:76论文数:394被引数:2.0万
L
Laura M. Selfors
H 指数:32论文数:152被引数:5,015
J
Joshua Munger
H 指数:33论文数:95被引数:7,288