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PD-L1 restrains PD-1+Nrp1lo+Nrp1 lo Treg cells to suppress inflammation-driven colorectal tumorigenesis Poschel, Dakota B.; Klement, John D.; Merting, Alyssa D.; Lu, Chunwan; Zhao, Yang; Yang, Dafeng; Xiao, Wei; Zhu, Huabin; Rajeshwari, Ponnala; Toscano, Michael; Jones, Kimya; Barrett, Amanda; Bollag, Roni J.; Fallon, Padraic G.; Shi, Huidong; Liu, Kebin 分享 收藏
Emergence of dysfunctional neutrophils with a defect in arginase-1 release in severe COVID-19 Dwivedi, Amrita; Mhaonaigh, Aisling Ui; Carroll, Makala; Khosravi, Bahareh; Batten, Isabella; Ballantine, Robert Sean; Phelan, Stuart Hendricken; O'Doherty, Laura; George, Angel Mary; Sui, Jacklyn; Hawerkamp, Heike C.; Fallon, Padraic G.; Noppe, Elne; Mason, Sabina; Conlon, Niall; Ni Cheallaigh, Cliona; Finlay, Conor M.; Little, Mark A. 分享 收藏
PD-L1-and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus Tchen, John; Simon, Quentin; Chapart, Lea; Thaminy, Morgane K.; Vibhushan, Shamila; Saveanu, Loredana; Lamri, Yasmine; Saidoune, Fanny; Pacreau, Emeline; Pellefigues, Christophe; Bex-coudrat, Julie; Karasuyama, Hajime; Miyake, Kensuke; Hidalgo, Juan; Fallon, Padraic G.; Papo, Thomas; Blank, Ulrich; Benhamou, Marc; Hanouna, Guillaume; Sacre, Karim; Daugas, Eric; Charles, Nicolas 分享 收藏
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4-Octyl Itaconate Alleviates Airway Eosinophilic Inflammation by Suppressing Chemokines and Eosinophil Development 衣康酸4-辛酯通过抑制趋化因子和嗜酸性粒细胞发育减轻气道嗜酸性粒细胞炎症 Yin, Maureen; Wadhwa, Ridhima; Marshall, Jacqueline E.; Gillis, Caitlin M.; Kim, Richard Y.; Dua, Kamal; Palsson-McDermott, Eva M.; Fallon, Padraic G.; Hansbro, Philip M.; ONeil, Luke A. J. 分享 收藏
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Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon (vol 14, 3513, 2023) 富马酸二甲酯和衣康酸4-辛酯是通过抑制I型干扰素抑制巨噬细胞组织因子的抗凝剂 (第14卷，3513，2023) Ryan, Tristram A. J.; Hooftman, Alexander; Rehill, Aisling M.; Johansen, Matt D.; O' Brien, Eoin C.; Toller-Kawahisa, Juliana E.; Wilk, Mieszko M.; Day, Emily A.; Weiss, Hauke J.; Sarvari, Pourya; Vozza, Emilio G.; Schramm, Fabian; Peace, Christian G.; Zotta, Alessia; Miemczyk, Stefan; Nalkurthi, Christina; Hansbro, Nicole G.; McManus, Gavin; O'Doherty, Laura; Gargan, Siobhan; Long, Aideen; Dunne, Jean; Cheallaigh, Cliona Ni; Conlon, Niall; Carty, Michael; Fallon, Padraic G.; Mills, Kingston H. G.; Creagh, Emma M.; O' Donnell, James S.; Hertzog, Paul J.; Hansbro, Philip M.; McLoughlin, Rachel M.; Wygrecka, Malgorzata; Preston, Roger J. S.; Zaslona, Zbigniew; O'Neill, Luke A. J. 分享 收藏
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Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon 富马酸二甲酯和衣康酸4-辛酯是通过抑制I型干扰素抑制巨噬细胞组织因子的抗凝剂 Ryan, Tristram A. J.; Hooftman, Alexander; Rehill, Aisling M.; Johansen, Matt D.; O'Brien, Eoin C.; Toller-Kawahisa, Juliana E.; Wilk, Mieszko M.; Day, Emily A.; Weiss, Hauke J.; Sarvari, Pourya; Vozza, Emilio G.; Schramm, Fabian; Peace, Christian G.; Zotta, Alessia; Miemczyk, Stefan; Nalkurthi, Christina; Hansbro, Nicole G.; McManus, Gavin; O'Doherty, Laura; Gargan, Siobhan; Long, Aideen; Dunne, Jean; Cheallaigh, Cliona Ni; Conlon, Niall; Carty, Michael; Fallon, Padraic G.; Mills, Kingston H. G.; Creagh, Emma M.; O'Donnell, James S.; Hertzog, Paul J.; Hansbro, Philip M.; McLoughlin, Rachel M.; Wygrecka, Malgorzata; Preston, Roger J. S.; Zaslona, Zbigniew; O'Neill, Luke A. J. 分享 收藏
Heterogeneity in the half-life of factor VIII concentrate in patients with hemophilia A is due to variability in the clearance of endogenous von Willebrand factor Elsheikh, Einas; Lavin, Michelle; Heck, Lilian Antunes; Larkin, Niamh; Mullaney, Brendan; Doherty, Dearbhla; Kennedy, Megan; Keenan, Catriona; Guest, Thomas; O'Mahony, Brian; Fazavana, Judicael; Fallon, Padraic G.; Preston, Roger J. S.; Gormley, John; Ryan, Kevin; O'Connell, Niamh M.; Singleton, Evelyn; Byrne, Mary; McGowan, Mark; Roche, Sheila; Doyle, Mairead; Crowley, Maeve P.; O'Shea, Susan I.; Reipert, Birgit M.; Johnson, Jill M.; Pipe, Steven W.; Di Paola, Jorge; Turecek, Peter L.; O'Donnell, James S.; iPATH study Grp 分享 收藏
Macrophage Galactose Lectin Contributes to the Regulation of FVIII (Factor VIII) Clearance in Mice-Brief Report Ward, Soracha E.; Guest, Thomas; Byrne, Ciara; Lopes, Patricia; O'Sullivan, Jamie M.; Doherty, Dearbhla; O'Connell, David; Gutierrez Llaneza, Sara; Chion, Alain; Fazavana, Judicael; Fallon, Padraic G.; Preston, Roger J. S.; Johnsen, Jill M.; Pipe, Steven W.; Turecek, Peter L.; O'Donnell, James S. 分享 收藏
Characterisation of the pro-inflammatory cytokine signature in severe COVID-19 Hawerkamp, Heike C.; Dyer, Adam H.; Patil, Neha D.; McElheron, Matt; O'Dowd, Niamh; O'Doherty, Laura; Mhaonaigh, Aisling Ui; George, Angel M.; O'Halloran, Aisling M.; Reddy, Conor; Kenny, Rose Anne; Little, Mark A.; Martin-Loeches, Ignacio; Bergin, Colm; Kennelly, Sean P.; Donnelly, Seamas C.; Bourke, Nollaig M.; Long, Aideen; Sui, Jacklyn; Doherty, Derek G.; Conlon, Niall; Cheallaigh, Cliona Ni; Fallon, Padraic G. 分享 收藏
IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases IRAK4抑制抑制驱动炎症性皮肤病的致病过程 Lavazais, Stephanie; Jargosch, Manja; Dupont, Sonia; Labeguere, Frederic; Menet, Christel; Jagerschmidt, Catherine; Ohm, Frenz; Kupcsik, Laszlo; Parent, Isabelle; Cottereaux, Celine; Marsais, Florence; Oste, Line; Van de Water, An; Christophe, Thierry; De Vos, Steve; Fallon, Padraic; Lauffer, Felix; Clement-Lacroix, Philippe; Eyerich, Kilian; Brys, Reginald 分享 收藏
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von Willebrand factor links primary hemostasis to innate immunity Drakeford, Clive; Aguila, Sonia; Roche, Fiona; Hokamp, Karsten; Fazavana, Judicael; Cervantes, Mariana P.; Curtis, Annie M.; Hawerkamp, Heike C.; Dhami, Sukhraj Pal Singh; Charles-Messance, Hugo; Hackett, Emer E.; Chion, Alain; Ward, Soracha; Ahmad, Azaz; Schoen, Ingmar; Breen, Eamon; Keane, Joe; Murphy, Ross; Preston, Roger J. S.; O'Sullivan, Jamie M.; Sheedy, Frederick J.; Fallon, Padraic; O'Donnell, James S. 分享 收藏
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