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D

David O'Sullivan

Max Planck Institute for Immunobiology and Epigenetics
H指数:27
被引数:1.3万

个人简介

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教育背景

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工作经历

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荣誉奖项

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A STAT1/ETC/GBP1 axis represents a potential therapeutic target for noncommunicable granulomatous skin disease

STAT1/ETC/GBP1轴代表非传染性肉芽肿性皮肤疾病的潜在治疗靶点

Science Advances
IF12.5
2026-05-290
OA
Manuel Huerta Arana; Henning Klapproth; Michal A. Stanczak; Luisa Bopp; Karla Witschurke; Robert Seitz; Maria Lopéz Martinez; Jan Zamek; Sinika Henschke; Nisha Rana; David O’Sullivan; Joy Steinkamp; Jan-Wilm Lackmann; William Damsky; Esther von Stebut; David E. Sanin; Paola Zigrino; Ramon I. Klein Geltink; Edward J. Pearce; Erika L. Pearce; Mario Fabri
Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function
NATURE IMMUNOLOGY
IF27.6
2023-02-0216
OA
Edwards-Hicks, Joy; Apostolova, Petya; Buescher, Joerg M.; Maib, Hannes; Stanczak, Michal A.; Corrado, Mauro; Geltink, Ramon I. Klein I.; Maccari, Maria Elena; Villa, Matteo; Carrizo, Gustavo E.; Sanin, David E.; Baixauli, Francesc; Kelly, Beth; Curtis, Jonathan D.; Haessler, Fabian; Patterson, Annette; Field, Cameron S.; Caputa, George; Kyle, Ryan L.; Soballa, Melanie; Cha, Minsun; Paul, Harry; Martin, Jacob; Grzes, Katarzyna M.; Flachsmann, Lea; Mitterer, Michael; Zhao, Liang; Winkler, Frances; Rafei-Shamsabadi, David Ali; Meiss, Frank; Bengsch, Bertram; Zeiser, Robert; Puleston, Daniel J.; O'Sullivan, David; Pearce, Edward J.; Pearce, Erika L.
An LKB1–mitochondria axis controls TH17 effector function
Nature
IF48.5
2022-09-280
PRE
Francesc Baixauli; Klara Piletic; Daniel J. Puleston; Matteo Villa; Cameron S. Field; Lea J. Flachsmann; Andrea Quintana; Nisha Rana; Joy Edwards-Hicks; Mai Matsushita; Michal A. Stanczak; Katarzyna M. Grzes; Agnieszka M. Kabat; Mario Fabri; George Caputa; Beth Kelly; Mauro Corrado; Yaarub Musa; Katarzyna J. Duda; Gerhard Mittler; David O’Sullivan; Hiromi Sesaki; Thomas Jenuwein; Joerg M. Buescher; Edward J. Pearce; David E. Sanin; Erika L. Pearce
MR1-dependent immune surveillance of the skin contributes to pathogenesis and is a photobiological target of UV light therapy in a mouse model of atopic dermatitis
ALLERGY
IF12
2021-07-0715
OAAI
Naidoo, Karmella; Woods, Katherine; Pellefigues, Christophe; Cait, Alissa; O'Sullivan, David; Gell, Katie; Marshall, Andrew J.; Anderson, Regan J.; Li, Yanyan; Schmidt, Alfonso; Prasit, Kef; Mayer, Johannes U.; Gestin, Aurelie; Hermans, Ian F.; Painter, Gavin; Jacobsen, Elizabeth A.; Gasser, Olivier
Fever supports CD8+effector T cell responses by mitochondrial translation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-06-142
OAAI
'Sullivan, David O.; Stanczak, Michal A.; Villa, Matteo; Uhl, Franziska M.; Corrado, Mauro; Geltink, Ramon I. Klein; Sanin, David E.; Apostolova, Petya; Rana, Nisha; Edwards-Hicks, Joy; Grzes, Katarzyna M.; Kabat, Agnieszka M.; Kyle, Ryan L.; Fabri, Mario; Curtis, Jonathan D.; Buck, Michael D.; Patterson, Annette E.; Regina, Annamaria; Field, Cameron S.; Baixauli, Francesc; Puleston, Daniel J.; Pearce, Edward J.; Zeiser, Robert; Pearce, Erika L.
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity
CELL METABOLISM
IF30.9
2020-12-0140
OAAI
Corrado, Mauro; Edwards-Hicks, Joy; Villa, Matteo; Flachsmann, Lea J.; Sanin, David E.; Jacobs, Maaike; Baixauli, Francesc; Stanczak, Michal; Anderson, Eve; Azuma, Mai; Quintana, Andrea; Curtis, Jonathan D.; Clapes, Thomas; Grzes, Katarzyna M.; Kabat, Agnieszka M.; Kyle, Ryan; Patterson, Annette E.; Geltink, Ramon Klein; Amulic, Borko; Steward, Colin G.; Strathdee, Douglas; Trompouki, Eirini; O'Sullivan, David; Pearce, Edward J.; Pearce, Erika L.
Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans

供体T细胞的代谢重编程增强了小鼠和人类的移植物抗白血病作用

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2020-10-2882
OAAI
Uhl, Franziska M.; Chen, Sophia; O'Sullivan, David; Edwards-Hicks, Joy; Richter, Gesa; Haring, Eileen; Andrieux, Geoffroy; Halbach, Sebastian; Apostolova, Petya; Buscher, Jorg; Duquesne, Sandra; Melchinger, Wolfgang; Sauer, Barbara; Shoumariyeh, Khalid; Schmitt-Graeff, Annette; Kreutz, Marina; Lubbert, Michael; Duyster, Justus; Brummer, Tilman; Boerries, Melanie; Madl, Tobias; Blazar, Bruce R.; Gross, Olaf; Pearce, Erika L.; Zeiser, Robert
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy

CD8效应T细胞的代谢调节用于过继细胞治疗

NATURE METABOLISM
IF20.8
2020-08-0398
OAAI
Geltink, Ramon I. Klein; Edwards-Hicks, Joy; Apostolova, Petya; O'Sullivan, David; Sanin, David E.; Patterson, Annette E.; Puleston, Daniel J.; Ligthart, Nina A. M.; Buescher, Joerg M.; Grzes, Katarzyna M.; Kabat, Agnieszka M.; Stanczak, Michal; Curtis, Jonathan D.; Hassler, Fabian; Uhl, Franziska M.; Fabri, Mario; Zeiser, Robert; Pearce, Edward J.; Pearce, Erika L.
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

多胺和eIF5A低钠调节线粒体呼吸和巨噬细胞活化

CELL METABOLISM
IF30.9
2019-08-01235
OAAI
Puleston, Daniel J.; Buck, Michael D.; Geltink, Ramon I. Klein; Kyle, Ryan L.; Caputa, George; OSullivan, David; Cameron, Alanna M.; Castoldi, Angela; Musa, Yaarub; Kabat, Agnieszka M.; Zhang, Ying; Flachsmann, Lea J.; Field, Cameron S.; Patterson, Annette E.; Scherer, Stefanie; Alfei, Francesca; Baixauli, Francesc; Austin, S. Kyle; Kelly, Beth; Matsushita, Mai; Curtis, Jonathan D.; Grzes, Katarzyna M.; Villa, Matteo; Corrado, Mauro; Sanin, David E.; Qiu, Jing; Pallman, Nora; Paz, Katelyn; Maccari, Maria Elena; Blazar, Bruce R.; Mittler, Gerhard; Buescher, Joerg M.; Zehn, Dietmar; Rospert, Sabine; Pearce, Edward J.; Balabanov, Stefan; Pearce, Erika L.
Acetate Promotes T Cell Effector Function during Glucose Restriction

乙酸在葡萄糖限制期间促进T细胞效应子功能

CELL REPORTS
IF6.9
2019-05-01238
OAAI
Qiu, Jing; Villa, Matteo; Sanin, David E.; Buck, Michael D.; O'Sullivan, David; Ching, Reagan; Matsushita, Mai; Grzes, Katarzyna M.; Winkler, Frances; Chang, Chih-Hao; Curtis, Jonathan D.; Kyle, Ryan L.; Bakker, Nikki Van Teijlingen; Corrado, Mauro; Haessler, Fabian; Alfei, Francesca; Edwards-Hicks, Joy; Maggi, Leonard B., Jr.; Zehn, Dietmar; Egawa, Takeshi; Bengsch, Bertram; Geltink, Ramon I. Klein; Jenuwein, Thomas; Pearce, Edward J.; Pearce, Erika L.
Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2
IMMUNITY
IF26.3
2018-12-0184
OAAI
Sanin, David E.; Matsushita, Mai; Geltink, Ramon I. Klein; Grzes, Katarzyna M.; Bakker, Nikki van Teijlingen; Corrado, Mauro; Kabat, Agnieszka M.; Buck, Michael D.; Qiu, Jing; Lawless, Simon J.; Cameron, Alanna M.; Villa, Matteo; Baixauli, Francesc; Patterson, Annette E.; Haessler, Fabian; Curtis, Jonathan D.; O'Neill, Christina M.; O'Sullivan, David; Wu, Duojiao; Mittler, Gerhard; Huang, Stanley Ching-Cheng; Pearce, Erika L.; Pearce, Edward J.

研究方向

暂未获取到该数据
E
Erika L. Pearce
H 指数:64论文数:222被引数:3.7万
D
David E. Sanin
H 指数:33论文数:107被引数:6,876
J
Jonathan D. Curtis
H 指数:27论文数:35被引数:1.2万
E
Edward J. Pearce
H 指数:0论文数:3被引数:188
M
Michael D. Buck
H 指数:36论文数:85被引数:1.2万
R
Robert Zeiser
H 指数:78论文数:631被引数:2.5万
P
Petya Apostolova
H 指数:27论文数:117被引数:2,911
M
Mauro Corrado
H 指数:26论文数:46被引数:4,837
K
Katarzyna M. Grzes
H 指数:22论文数:39被引数:3,749
M
Matteo Villa
H 指数:22论文数:49被引数:3,267