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Interleukin-12 decorated nanosized semiflexible Immunofilaments enable directed targeting and augmented IFNγ responses of natural killer cells 白介素-12修饰的纳米级半柔性免疫原纤维能够实现自然杀伤细胞的定向靶向和增强的IFNγ反应。 Weiss, L; Schluck, M; Classens, R; de Jonge, PKJD; van der Waart, A; Nguyen, KG; Nguyen, TT; Zaharoff, DA; Malmberg, KJ; Dolstra, H; Figdor, CG; Sohlberg, E; Hammink, R 分享 收藏
Alloimmune Defense Receptor Combined with Genetic Ablation of Adhesion Ligand CD58 Is a Comprehensive Approach to Promote Functional Persistence of Allogeneic Cell Therapies without Conditioning Chemotherapy 同种免疫防御受体与粘附配体CD58的遗传剔除相结合是一种促进异基因细胞疗法功能持久性的综合方法，无需条件性化疗。 Williams, Alan; Mbofung, Rina; Morales-Mantilla, Daniel; Groff, Brian; O'Connor, Alison; Li, Binzhong; Janani, Ramesh; Rezner, Betsy; Jelcic, Mark; Pan, Yijia; Lee, Tom; Malmberg, Karl-Johan; Mamonkin, Maksim; Goulding, John; Goodridge, Jode; Valamehr, Bahram 分享 收藏
The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration Palacios, Daniel; Majhi, Rakesh Kumar; Szabo, Edina K.; Clement, Dennis; Lachota, Mieszko; Netskar, Herman; Penna, Leena; Krokeide, Silje Z.; Vincenti, Marianna; Kveberg, Lise; Malmberg, Karl-Johan 分享 收藏
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies Hammer, Quirin; Perica, Karlo; Mbofung, Rina M.; van Ooijen, Hanna; Martin, Karen E.; Momayyezi, Pouria; Varady, Erika; Pan, Yijia; Jelcic, Mark; Groff, Brian; Abujarour, Ramzey; Krokeide, Silje Z.; Lee, Tom; Williams, Alan; Goodridge, Jode P.; Valamehr, Bahram; Onfelt, Bjorn; Sadelain, Michel; Malmberg, Karl-Johan 分享 收藏
High-dimensional single-cell analysis of human natural killer cell heterogeneity 人类自然杀伤细胞异质性的高维单细胞分析 Rebuffet, Lucas; Melsen, Janine E.; Escaliere, Bertrand; Basurto-Lozada, Daniela; Bhandoola, Avinash; Bjorkstrom, Niklas K.; Bryceson, Yenan T.; Castriconi, Roberta; Cichocki, Frank; Colonna, Marco; Davis, Daniel M.; Diefenbach, Andreas; Ding, Yi; Haniffa, Muzlifah; Horowitz, Amir; Lanier, Lewis L.; Malmberg, Karl-Johan; Miller, Jeffrey S.; Moretta, Lorenzo; Narni-Mancinelli, Emilie; O'Neill, Luke A. J.; Romagnani, Chiara; Ryan, Dylan G.; Sivori, Simona; Sun, Dan; Vagne, Constance; Vivier, Eric 分享 收藏
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping 通过转录参考图谱对肿瘤浸润性自然杀伤细胞进行泛癌症分析 Netskar, Herman; Pfefferle, Aline; Goodridge, Jodie P.; Sohlberg, Ebba; Dufva, Olli; Teichmann, Sarah A.; Brownlie, Demi; Michaelsson, Jakob; Marquardt, Nicole; Clancy, Trevor; Horowitz, Amir; Malmberg, Karl-Johan 分享 收藏
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Systematic evaluation of donor-KIR/recipient-HLA interactions in HLA-matched hematopoietic cell transplantation for AML Fein, Joshua A.; Shouval, Roni; Krieger, Elizabeth; Spellman, Stephen R.; Wang, Tao; Baldauf, Henning; Fleischhauer, Katharina; Kroger, Nicolaus; Horowitz, Mary; Maiers, Martin; Miller, Jeffrey S.; Mohty, Mohamad; Nagler, Arnon; Weisdorf, Daniel; Malmberg, Karl-Johan; Toor, Amir A.; Schetelig, Johannes; Romee, Rizwan; Koreth, John 分享 收藏
Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine 绘制NK细胞的趋化景观揭示了对双重趋化因子的子集特异性协同迁移反应 Lachota, Mieszko; Zielniok, Katarzyna; Palacios, Daniel; Kanaya, Minoru; Peena, Leena; Hoel, Hanna Julie; Wiiger, Merete Thune; Kveberg, Lise; Hautz, Wojciech; Zagozdzon, Radoslaw; Malmberg, Karl-Johan 分享 收藏
The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk Clement, Dennis; Szabo, Edina K.; Krokeide, Silje Zandstra; Wiiger, Merete Thune; Vincenti, Marianna; Palacios, Daniel; Chang, Young-Tae; Grimm, Christian; Patel, Sandip; Stenmark, Harald; Brech, Andreas; Majhi, Rakesh Kumar; Malmberg, Karl-Johan 分享 收藏
Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires Philippon, Camille; Tao, Sudan; Clement, Dennis; Haroun-Izquierdo, Alvaro; Kichula, Katherine M.; Netskar, Herman; Brandt, Ludwig; Oei, Vincent Sheng; Kanaya, Minoru; Lanuza, Pilar Maria; Schaffer, Marie; Goodridge, Jodie P.; Horowitz, Amir; Zhu, Faming; Hammer, Quirin; Sohlberg, Ebba; Majhi, Rakesh Kumar; Kveberg, Lise; Onfelt, Bjorn; Norman, Paul J.; Malmberg, Karl-Johan 分享 收藏
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Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma Cichocki, Frank; Bjordahl, Ryan; Goodridge, Jodie P.; Mahmood, Sajid; Gaidarova, Svetlana; Abujarour, Ramzey; Davis, Zachary B.; Merino, Aimee; Tuininga, Katie; Wang, Hongbo; Kumar, Akhilesh; Groff, Brian; Witty, Alec; Bonello, Greg; Huffman, Janel; Dailey, Thomas; Lee, Tom T.; Malmberg, Karl-Johan; Walcheck, Bruce; Hoepken, Uta; Rehm, Armin; Valamehr, Bahram; Miller, Jeffrey S. 分享 收藏
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia Haroun-Izquierdo, Alvaro; Vincenti, Marianna; Netskar, Herman; van Ooijen, Hanna; Zhang, Bin; Bendzick, Laura; Kanaya, Minoru; Momayyezi, Pouria; Li, Shuo; Wiiger, Merete Thune; Hoel, Hanna Julie; Krokeide, Silje Zandstra; Kremer, Veronika; Tjonnfjord, Geir; Berggren, Stephanie; Wikstroem, Kristina; Blomberg, Pontus; Alici, Evren; Felices, Martin; oenfelt, Bjoern; Hoeglund, Petter; Valamehr, Bahram; Ljunggren, Hans-Gustaf; Bjoerklund, Andreas; Hammer, Quirin; Kveberg, Lise; Cichocki, Frank; Miller, Jeffrey S.; Malmberg, Karl-Johan; Sohlberg, Ebba 分享 收藏
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