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S

Sabine Spath

incephalo ag
H指数:12
被引数:1,996

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Treatment efficacy in murine and human glioma models with brain Compartment-Locked IL-12 does not per se rely on influx of peripheral immune cells and induces distinct transcriptome and secretome changes

脑室锁定IL-12在鼠类和人类胶质瘤模型中的治疗效果并不直接依赖于外周免疫细胞的流入，并诱导了独特的转录组和分泌组变化。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Spath, Sabine; Le Large, Lea; Beffinger, Michal; Tatari, Nazanin; Ritz, Marie-Francoise; Taskoparan, Betul; Salazar, Ulisse; Deplazes, Sereina; Behr, Felix; Zinner, Carl Philipp; Vader, Willemijn; Bertozzi, Carlo; Van Der Meer, Donny; Hutter, Gregor; Vom Berg, Johannes
FcRn-silencing of IL-12Fc prevents toxicity of local IL-12 therapy and prolongs survival in experimental glioblastoma

FcRn沉默的IL-12Fc可预防局部IL-12疗法的毒性并延长实验性胶质母细胞瘤的生存期

Nature Communications
IF15.7
2025-05-220
OAAI
Michal Beffinger; Linda Schellhammer; Betül Taskoparan; Sereina Deplazes; Ulisse Salazar; Nazanin Tatari; Frauke Seehusen; Leopold von Balthazar; Carl Philipp Zinner; Sabine Spath; Tala Shekarian; Marie-Françoise Ritz; Marta McDaid; Pascal Egloff; Iwan Zimmermann; Hideho Okada; E. Sally Ward; Jack Rohrer; Markus A. Seeger; Thorsten Buch; Gregor Hutter; Johannes vom Berg
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
CELL METABOLISM
IF30.9
2024-08-012
OAAI
Bonetti, Lynn; Horkova, Veronika; Grusdat, Melanie; Longworth, Joseph; Guerra, Luana; Kurniawan, Henry; Franchina, Davide G.; Soriano-Baguet, Leticia; Binsfeld, Carole; Verschueren, Charlene; Spath, Sabine; Ewen, Anouk; Koncina, Eric; Gerardy, Jean-Jacques; Kobayashi, Takumi; Dostert, Catherine; Farinelle, Sophie; Harm, Janika; Fan, Yu-Tong; Chen, Ying; Harris, Isaac S.; Lang, Philipp A.; Vasiliou, Vasilis; Waisman, Ari; Letellier, Elisabeth; Becher, Burkhard; Mittelbronn, Michel; Brenner, Dirk
FOXP3 exon 2 controls Treg stability and autoimmunity
SCIENCE IMMUNOLOGY
IF16.3
2022-06-2438
OA
Du, Jianguang; Wang, Qun; Yang, Shuangshuang; Chen, Si; Fu, Yongyao; Spath, Sabine; Domeier, Phillip; Hagin, David; Anover-Sombke, Stephanie; Haouili, Maya; Liu, Sheng; Wan, Jun; Han, Lei; Liu, Juli; Yang, Lei; Sangani, Neel; Li, Yujing; Lu, Xiongbin; Janga, Sarath Chandra; Kaplan, Mark H.; Torgerson, Troy R.; Ziegler, Steven F.; Zhou, Baohua
Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells

移植物抗宿主病，而不是移植物抗白血病免疫，是由gm-csf许可的髓样细胞介导的

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2018-11-2863
OAAI
Tugues, Sonia; Amorim, Ana; Spath, Sabine; Martin-Blondel, Guillaume; Schreiner, Bettina; De Feo, Donatella; Lutz, Mirjam; Guscetti, Franco; Apostolova, Petya; Haftmann, Claudia; Hasselblatt, Peter; Nunez, Nicolas G.; Hottiger, Michael O.; van den Broek, Maries; Manz, Markus G.; Zeiser, Robert; Becher, Burkhard
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells (vol 24, pg 282, 2018)
NATURE MEDICINE
IF50
2018-04-0113
OAAI
Mathew, Nimitha R.; Baumgartner, Francis; Braun, Lukas; O'Sullivan, David; Thomas, Simone; Waterhouse, Miguel; Mueller, Tony A.; Hanke, Kathrin; Taromi, Sanaz; Apostolova, Petya; Illert, Anna L.; Melchinger, Wolfgang; Duquesne, Sandra; Schmitt-Graeff, Annette; Osswald, Lena; Yan, Kai-Li; Weber, Arnim; Tugues, Sonia; Spath, Sabine; Pfeifer, Dietmar; Follo, Marie; Claus, Rainer; Luebbert, Michael; Rummelt, Christoph; Bertz, Hartmut; Waesch, Ralph; Haag, Johanna; Schmidts, Andrea; Schultheiss, Michael; Bettinger, Dominik; Thimme, Robert; Ullrich, Evelyn; Tanriver, Yakup; Giang Lam Vuong; Arnold, Renate; Hemmati, Philipp; Wolf, Dominik; Ditschkowski, Markus; Jilg, Cordula; Wilhelm, Konrad; Leiber, Christian; Gerull, Sabine; Halter, Joerg; Lengerke, Claudia; Pabst, Thomas; Schroeder, Thomas; Kobbe, Guido; Roesler, Wolf; Doostkam, Soroush; Meckel, Stephan; Stabla, Kathleen; Metzelder, Stephan K.; Halbach, Sebastian; Brummer, Tilman; Hu, Zehan; Dengjel, Joern; Hackanson, Bjoern; Schmid, Christoph; Holtick, Udo; Scheid, Christof; Spyridonidis, Alexandros; Stoelzel, Friedrich; Ordemann, Rainer; Mueller, Lutz P.; Sicre-de-Fontbrune, Flore; Ihorst, Gabriele; Kuball, Juergen; Ehlert, Jan E.; Feger, Daniel; Wagner, Eva-Maria; Cahn, Jean-Yves; Schnell, Jacqueline; Kuchenbauer, Florian; Bunjes, Donald; Chakraverty, Ronjon; Richardson, Simon; Gill, Saar; Kroeger, Nicolaus; Ayuk, Francis; Vago, Luca; Ciceri, Fabio; Mueller, Antonia M.; Kondo, Takeshi; Teshima, Takanori; Klaeger, Susan; Kuster, Bernhard; Kim, Dennis (Dong Hwan); Weisdorf, Daniel; van der Velden, Walter; Doerfel, Daniela; Bethge, Wolfgang; Hilgendorf, Inken; Hochhaus, Andreas; Andrieux, Geoffroy; Boerries, Melanie; Busch, Hauke; Magenau, John; Reddy, Pavan; Labopin, Myriam; Antin, Joseph H.; Henden, Andrea S.; Hill, Geoffrey R.; Kennedy, Glen A.; Bar, Merav; Sarma, Anita; McLornan, Donal; Mufti, Ghulam; Oran, Betul; Rezvani, Katayoun; Shah, Omid; Negrin, Robert S.; Nagler, Arnon; Prinz, Marco; Burchert, Andreas; Neubauer, Andreas; Beelen, Dietrich; Mackensen, Andreas; von Bubnoff, Nikolas; Herr, Wolfgang; Becher, Burkhard; Socie, Gerard; Caligiuri, Michael A.; Ruggiero, Eliana; Bonini, Chiara; Haecker, Georg; Duyster, Justus; Finke, Juergen; Pearce, Erika; Blazar, Bruce R.; Zeiser, Robert
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

索拉非尼通过在FLT3-ITD-mutant白血病细胞中产生IL-15促进小鼠和人类的移植物抗白血病活性

NATURE MEDICINE
IF50
2018-02-12236
OAAI
Mathew, Nimitha R.; Baumgartner, Francis; Braun, Lukas; O'Sullivan, David; Thomas, Simone; Waterhouse, Miguel; Mueller, Tony A.; Hanke, Kathrin; Taromi, Sanaz; Apostolova, Petya; Illert, Anna L.; Melchinger, Wolfgang; Duquesne, Sandra; Schmitt-Graeff, Annette; Osswald, Lena; Yan, Kai-Li; Weber, Arnim; Tugues, Sonia; Spath, Sabine; Pfeifer, Dietmar; Follo, Marie; Claus, Rainer; Luebbert, Michael; Rummelt, Christoph; Bertz, Hartmut; Waesch, Ralph; Haag, Johanna; Schmidts, Andrea; Schultheiss, Michael; Bettinger, Dominik; Thimme, Robert; Ullrich, Evelyn; Tanriver, Yakup; Vuong, Giang Lam; Arnold, Renate; Hemmati, Philipp; Wolf, Dominik; Ditschkowski, Markus; Jilg, Cordula; Wilhelm, Konrad; Leiber, Christian; Gerull, Sabine; Halter, Joerg; Lengerke, Claudia; Pabst, Thomas; Schroeder, Thomas; Kobbe, Guido; Roesler, Wolf; Doostkam, Soroush; Meckel, Stephan; Stabla, Kathleen; Metzelder, Stephan K.; Halbach, Sebastian; Brummer, Tilman; Hu, Zehan; Dengjel, Joern; Hackanson, Bjoern; Schmid, Christoph; Holtick, Udo; Scheid, Christof; Spyridonidis, Alexandros; Stoelzel, Friedrich; Ordemann, Rainer; Mueller, Lutz P.; Sicre-de-Fontbrune, Flore; Ihorst, Gabriele; Kuball, Juergen; Ehlert, Jan E.; Feger, Daniel; Wagner, Eva-Maria; Cahn, Jean-Yves; Schnell, Jacqueline; Kuchenbauer, Florian; Bunjes, Donald; Chakraverty, Ronjon; Richardson, Simon; Gill, Saar; Kroeger, Nicolaus; Ayuk, Francis; Vago, Luca; Ciceri, Fabio; Mueller, Antonia M.; Kondo, Takeshi; Teshima, Takanori; Klaeger, Susan; Kuster, Bernhard; Kim, Dennis (Dong Hwan); Weisdorf, Daniel; van der Velden, Walter; Doerfel, Daniela; Bethge, Wolfgang; Hilgendorf, Inken; Hochhaus, Andreas; Andrieux, Geoffroy; Boerries, Melanie; Busch, Hauke; Magenau, John; Reddy, Pavan; Labopin, Myriam; Antin, Joseph H.; Henden, Andrea S.; Hill, Geoffrey R.; Kennedy, Glen A.; Bar, Merav; Sarma, Anita; McLornan, Donal; Mufti, Ghulam; Oran, Betul; Rezvani, Katayoun; Shah, Omid; Negrin, Robert S.; Nagler, Arnon; Prinz, Marco; Burchert, Andreas; Neubauer, Andreas; Beelen, Dietrich; Mackensen, Andreas; von Bubnoff, Nikolas; Herr, Wolfgang; Becher, Burkhard; Socie, Gerard; Caligiuri, Michael A.; Ruggiero, Eliana; Bonini, Chiara; Haecker, Georg; Duyster, Justus; Finke, Juergen; Pearce, Erika; Blazar, Bruce R.; Zeiser, Robert

研究方向

暂未获取到该数据
B
Burkhard Becher
H 指数:104论文数:529被引数:4.5万
R
Robert Zeiser
H 指数:78论文数:631被引数:2.5万
P
Petya Apostolova
H 指数:27论文数:117被引数:2,933
S
Sònia Tugues
H 指数:32论文数:111被引数:6,355
B
Bettina Schreiner
H 指数:34论文数:111被引数:6,496
P
Pavan Reddy
H 指数:68论文数:411被引数:1.6万
J
Justus Duyster
H 指数:68论文数:573被引数:1.7万
N
Nikolas von Bubnoff
H 指数:50论文数:346被引数:1.0万
F
Fabio Ciceri
H 指数:116论文数:1,425被引数:5.7万
M
Marco Prinz
H 指数:127论文数:725被引数:7.6万