Hiroyuki Hosokawa - Publications, H-index & Citations

Hiroyuki Hosokawa

Tokai University School of Medicine

44H指数

255论文数

7.2K被引数

收录论文 81

发表时间

sPLA2-reacted extracellular vesicles (SPLEVs) as a therapeutic modality for cytokine storm syndromes sPLA2-反应的细胞外囊泡（SPLEVs）作为细胞因子风暴综合征的治疗模式

Science Advances

IF12.5

2026-07-31

OAAI

Shunya Nakayama; Akane Kanamori; Takeshi Kamakura; Kosuke Kamiya; Kai Kudo; Ryo Yanagiya; Takanobu Shimizu; Yoshimi Miki; Yuki Nagasaki; Masaya Araki; Koichiro Tateishi; Yoko Ito; Yoshiki Shiraishi; Yasushi Nakamoto; Hiroyuki Hosokawa; Yumi Matsuzaki; Hitoshi Shimano; Koichiro Asano; Norio Yamamoto; Makoto Murakami; Ai Kotani

Ambra1 is essential for fasting-induced lipolysis via ATGL translocation to lipid droplets Ambra1通过介导ATGL易位至脂滴对禁食诱导的脂解作用至关重要

Biochemical and Biophysical Research Communications

IF2.2

2026-06-19

PREAI

Tomohiro Kashikawa; Hisako Akatsuka; Takahiro Suzuki; Hiroyuki Hosokawa; Norio Yamamoto; Katsuto Hozumi; Takehito Sato

Targeting notch signaling to restore neural development and behavior in mouse models of ASD 靶向Notch信号通路以恢复自闭症谱系障碍(ASD)小鼠模型中的神经发育和行为

Nature Communications

IF15.7

2026-03-30

OAAI

Yoko Hanno; Moe Nakanishi; Akinori Takase; Jun Nomura; Masami Tanaka; Yumi Iida; Masayuki Tanaka; Hiroyuki Hosokawa; Masatoshi Ito; Katsunaka Mikami; Katsuto Hozumi; Goichi Miyoshi; Toru Takumi; Takatoshi Iijima

Inflammatory macrophage-derived plasminogen activator inhibitor-1 exacerbates inflammation through efferocytosis inhibition 炎性巨噬细胞衍生的纤溶酶原激活物抑制剂-1通过抑制胞吐作用加剧炎症

Cell Death Discovery

IF7

2026-03-27

OAAI

Abd Aziz Ibrahim; Hiromi Miura; Tomoya Terada; Masaki Kawarada; Nobuo Watanabe; Hiroyuki Hosokawa; Masato Ohtsuka; Toshio Miyata; Takashi Yahata

Notch interaction with RUNX factors regulates initiation of the T-lineage program Kama, Y.; Hirano, K.-i.; Masuhara, K.; Endo, Y.; Suzuki, Y.; Fujimoto, M.; Matsuda, T.; Yahata, T.; Kato, M.; Hozumi, K.; et al. Notch与Runx因子的相互作用调控T系程序的启动。J. Exp. Med. 2026, 223, e20250911. [Google Scholar] [CrossRef]

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2025-12-04

OAAI

Kama, Yuichi; Hirano, Ken-ichi; Masuhara, Kaori; Endo, Yusuke; Suzuki, Yuka; Fujimoto, Masanori; Matsuda, Tatsuma; Yahata, Takashi; Kato, Masahiko; Hozumi, Katsuto; Tanaka, Tomoaki; Hosokawa, Hiroyuki

Plasminogen activator inhibitor-1 promotes immune evasion in tumors by facilitating the expression of programmed cell death-ligand 1

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-05-08

OAAI

Ibrahim, Abd Aziz; Fujimura, Taku; Uno, Tomoko; Terada, Tomoya; Hirano, Ken-ichi; Hosokawa, Hiroyuki; Ohta, Akio; Miyata, Toshio; Ando, Kiyoshi; Yahata, Takashi

Bayesian optimization of ball milling conditions to obtain highly crystal-oriented Sm-Fe-N powder

JOURNAL OF ALLOYS AND COMPOUNDS

IF6.3

2023-05-01

PREAI

Shimojima, K.; Kashiwaya, H.; Hosokawa, H.

Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-11-01

OAAI

Koizumi, Maria; Kama, Yuichi; Hirano, Ken-ichi; Endo, Yusuke; Tanaka, Tomoaki; Hozumi, Katsuto; Hosokawa, Hiroyuki

Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis

NATURE COMMUNICATIONS

IF15.7

2022-09-15

OAAI

Fujimoto, Masanori; Yokoyama, Masataka; Kiuchi, Masahiro; Hosokawa, Hiroyuki; Nakayama, Akitoshi; Hashimoto, Naoko; Sakuma, Ikki; Nagano, Hidekazu; Yamagata, Kazuyuki; Kudo, Fujimi; Manabe, Ichiro; Lee, Eunyoung; Hatano, Ryo; Onodera, Atsushi; Hirahara, Kiyoshi; Yokote, Koutaro; Miki, Takashi; Nakayama, Toshinori; Tanaka, Tomoaki

GLS2 Is a Tumor Suppressor and a Regulator of Ferroptosis in Hepatocellular Carcinoma

CANCER RESEARCH

IF16.6

2022-07-27

OAAI

Suzuki, Sawako; Venkatesh, Divya; Kanda, Hiroaki; Nakayama, Akitoshi; Hosokawa, Hiroyuki; Lee, Eunyoung; Miki, Takashi; Stockwell, Brent R.; Yokote, Koutaro; Tanaka, Tomoaki; Prives, Carol

Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-03-17

OAAI

Hirano, Ken-ichi; Hosokawa, Hiroyuki; Yahata, Takashi; Ando, Kiyoshi; Tanaka, Masayuki; Imai, Jin; Yazawa, Masaki; Ohtsuka, Masato; Negishi, Naoko; Habu, Sonoko; Sato, Takehito; Hozumi, Katsuto

LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice

ELIFE

IF0

2021-08-12

OAAI

Hirano, Ken-ichi; Hosokawa, Hiroyuki; Koizumi, Maria; Endo, Yusuke; Yahata, Takashi; Ando, Kiyoshi; Hozumi, Katsuto

Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-06-28

OAAI

Hosokawa, Hiroyuki; Koizumi, Maria; Masuhara, Kaori; Romero-Wolf, Maile; Tanaka, Tomoaki; Nakayama, Toshinori; Rothenberg, Ellen, V

Transcription factors regulate early T cell development via redeployment of other factors Functional dynamics of constitutively required factors in cell fate decisions 转录因子通过重新部署其他因子调节早期T细胞发育细胞命运决定中组成型必需因子的功能动力学

BIOESSAYS

IF2.7

2021-02-24

PREAI

Hosokawa, Hiroyuki; Masuhara, Kaori; Koizumi, Maria

Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-01-21

OAAI

Shin, Boyoung; Hosokawa, Hiroyuki; Romero-Wolf, Maile; Zhou, Wen; Masuhara, Kaori; Tobin, Victoria R.; Levanon, Ditsa; Groner, Yoram; Rothenberg, Ellen, V

How transcription factors drive choice of the T cell fate 转录因子如何驱动T细胞命运的选择

NATURE REVIEWS IMMUNOLOGY

IF60.9

2020-09-11

166

OAAI

Hosokawa, Hiroyuki; Rothenberg, Ellen, V

Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development

JOURNAL OF CELL BIOLOGY

IF6.4

2020-08-05

OAAI

Romero-Wolf, Maile; Shin, Boyoung; Zhou, Wen; Koizumi, Maria; Rothenberg, Ellen, V; Hosokawa, Hiroyuki

Cell type-specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2019-10-25

OAAI

Hosokawa, Hiroyuki; Romero-Wolf, Maile; Yang, Qi; Motomura, Yasutaka; Levanon, Ditsa; Groner, Yoram; Moro, Kazuyo; Tanaka, Tomoaki; Rothenberg, Ellen, V

Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development 造血转录因子PU.1在T细胞发育启动中的作用机制

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-02-20

OAAI

Rothenberg, Ellen V.; Hosokawa, Hiroyuki; Ungerback, Jonas

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

NATURE IMMUNOLOGY

IF27.6

2018-10-30

OAAI

Hosokawa, Hiroyuki; Romero-Wolf, Maile; Yui, Mary A.; Ungerback, Jonas; Quiloan, Maria L. G.; Matsumoto, Masaki; Nakayama, Keiichi I.; Tanaka, Tomoaki; Rothenberg, Ellen V.

研究方向