Michel Desjardins - Publications, H-index & Citations

Michel Desjardins

université de montreal

51H指数

238论文数

1.2W被引数

收录论文 50

发表时间

STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation STING下调未折叠蛋白反应以在炎症期间通过MHC-I呈现自身抗原

Cell Reports

IF6.9

2026-06-11

OAAI

Ahmed M. Fahmy; Ali Ahmadi; Joël Lanoix; Tyler Cannon; Moustafa N. Elemeery; Camberly Hernandez Paredes; Benoit Barrette; Eric Bonneil; Yong Zhong Xu; Maha Ibrahim; Guillermo Arango-Duque; Eric Olivier Audemard; Sébastien Lemieux; Eric Chevet; Erwin Schurr; Philippe Pierre; Samantha Gruenheid; Pierre Thibault; Heidi M. McBride; Michel Desjardins

Author Correction: Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis 作者更正：Lrrk2 G2019S突变引发模型中感染性结肠炎的细胞固有中性粒细胞效应功能增强和肠道炎症。

npj Parkinson's Disease

IF8.2

2026-03-13

OAAI

Jessica Pei; Nathalia L. Oliveira; Sherilyn J. Recinto; Alexandra Kazanova; Celso M. Queiroz-Junior; Ziyi Li; Katalina Couto; Susan Westfall; Ahmed M. Fahmy; Camila Tiefensee-Ribeiro; Irah L. King; Austen J. Milnerwood; Michel Desjardins; Ajitha Thanabalasuriar; Jo Anne Stratton; Samantha Gruenheid

The Parkinson's Disease-associated mutation LRRK2 G2019S impacts neutrophil effector functions and the response to intestinal infection in mice

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Gruenheid, Samantha; Pei, Jessica; Oliveira, Nathalia; Recinto, Sherilyn; Kazanova, Alexandra; Queiroz-Junior, Celso; Li, Ziyi; Couto, Katalina; Westfall, Susan; King, Irah L.; Ribeiro, Camila; Milnerwood, Austen; Desjardins, Michel; Thanabalasuriar, Ajitha; Stratton, Jo Anne

Modeling gene-environment interactions in Parkinson's Disease: Helicobacter pylori induces CD8 T cell associated motor phenotype in PINK1-/- mice 帕金森病的基因-环境相互作用模型: 幽门螺杆菌在PINK1-/-小鼠中诱导CD8 T细胞相关的运动表型

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Kazanova, Alexandra; Sung, Jacqueline; Bessaiah, Hicham; Oliveira, Nathalia; Gavino, Christina; Recinto, Sherilyn J.; Pei, Jessica; Burns, Lindsay; Miller, Willemien; Brouillard-Galipeau, Morgane; Nouh Elemeery, Moustafa; Guerra, Lucia; Macdonald, Adam; Lanoix, Joel; Thibault, Pierre; McBride, Heidi; Desjardins, Michel; Stratton, Jo Anne; Labrecque, Nathalie; Gruenheid, Samantha

MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death MAPL调节gasdermin介导的溶酶体释放mtDNA，以驱动热病细胞死亡

Nature Cell Biology

IF19.1

2025-10-13

OAAI

Mai Nguyen; Jack J. Collier; Olesia Ignatenko; Genevieve Morin; Vanessa Goyon; Alexandre Janer; Camila Tiefensee Ribeiro; Austen J. Milnerwood; Sidong Huang; Michel Desjardins; Heidi M. McBride

Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis Lrrk2 G2019S突变引发感染性结肠炎模型中细胞内固有中性粒细胞效应功能的增加和肠道炎症

npj Parkinson's Disease

IF0

2025-08-29

OAAI

Antigen cross-presentation: proteasome location, location, location

EMBO JOURNAL

IF8.3

2019-07-31

OAAI

Desjardins, Michel

Mitochondrial antigen presentation: a mechanism linking Parkinson's disease to autoimmunity

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2019-06-01

PREAI

Fahmy, Ahmed M.; Boulais, Jonathan; Desjardins, Michel; Matheoud, Diana

The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2015-12-16

180

OAAI

Dieude, Melanie; Bell, Christina; Turgeon, Julie; Beillevaire, Deborah; Pomerleau, Luc; Yang, Bing; Hamelin, Katia; Qi, Shijie; Pallet, Nicolas; Beland, Chanel; Dhahri, Wahiba; Cailhier, Jean-Francois; Rousseau, Matthieu; Duchez, Anne-Claire; Levesque, Tania; Lau, Arthur; Rondeau, Christiane; Gingras, Diane; Muruve, Danie; Rivard, Alain; Cardinal, Heloise; Perreault, Claude; Desjardins, Michel; Boilard, Eric; Thibault, Pierre; Hebert, Marie-Josee

RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4

JOURNAL OF CELL BIOLOGY

IF6.4

2015-09-28

OAAI

Terawaki, Seigo; Camosseto, Voahirana; Prete, Francesca; Wenger, Till; Papadopoulos, Alexia; Rondeau, Christiane; Combes, Alexis; Rodrigues, Christian Rodriguez; Thien-Phong Vu Manh; Fallet, Mathieu; English, Luc; Santamaria, Rodrigo; Soares, Ana R.; Weil, Tobias; Hammad, Hamida; Desjardins, Michel; Gorvel, Jean-Pierre; Santos, Manuel A. S.; Gatti, Evelina; Pierre, Philippe

Nuclear membrane-derived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection

AUTOPHAGY

IF14.3

2014-10-27

OAAI

English, Luc; Chemali, Magali; Desjardins, Michel

Quantitative Proteomics Reveals the Induction of Mitophagy in Tumor Necrosis Factor-α-activated (TNFα) Macrophages

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2013-09-01

OAAI

Bell, Christina; English, Luc; Boulais, Jonathan; Chemali, Magali; Caron-Lizotte, Olivier; Desjardins, Michel; Thibault, Pierre

A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells

PROTEOMICS

IF3.9

2013-04-05

PREAI

Pallet, Nicolas; Sirois, Isabelle; Bell, Christina; Hanafi, Laila-Aicha; Hamelin, Katia; Dieude, Melanie; Rondeau, Christiane; Thibault, Pierre; Desjardins, Michel; Hebert, Marie-Josee

Inhibition of the Host Translation Shutoff Response by Herpes Simplex Virus 1 Triggers Nuclear Envelope-Derived Autophagy

JOURNAL OF VIROLOGY

IF3.8

2013-04-01

OAAI

Radtke, Kerstin; English, Luc; Rondeau, Christiane; Leib, David; Lippe, Roger; Desjardins, Michel

Proteomics Analysis of Herpes Simplex Virus Type 1-Infected Cells Reveals Dynamic Changes of Viral Protein Expression, Ubiquitylation, and Phosphorylation

JOURNAL OF PROTEOME RESEARCH

IF3.6

2013-03-04

PREAI

Bell, Christina; Desjardins, Michel; Thibault, Pierre; Radtke, Kerstin

Proteomic Characterization of Phagosomal Membrane Microdomains During Phagolysosome Biogenesis and Evolution

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2012-11-01

OAAI

Goyette, Guillaume; Boulais, Jonathan; Carruthers, Nicholas J.; Landry, Christian R.; Jutras, Isabelle; Duclos, Sophie; Dermine, Jean-Francois; Michnick, Stephen W.; LaBoissiere, Sylvie; Lajoie, Gilles; Barreiro, Luis; Thibault, Pierre; Desjardins, Michel

Quantitative Proteomics Reveals That Only a Subset of the Endoplasmic Reticulum Contributes to the Phagosome

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2012-07-01

OAAI

Campbell-Valois, Francois-Xavier; Trost, Matthias; Chemali, Magali; Dill, Brian D.; Laplante, Annie; Duclos, Sophie; Sadeghi, Shayan; Rondeau, Christiane; Morrow, Isabel C.; Bell, Christina; Gagnon, Etienne; Hatsuzawa, Kiyokata; Thibault, Pierre; Desjardins, Michel

Human invariant chain isoform p35 restores thymic selection and antigen presentation in CD74-deficient mice

IMMUNOLOGY AND CELL BIOLOGY

IF3

2012-06-12

PREAI

Geneve, Laetitia; Chemali, Magali; Desjardins, Michel; Labrecque, Nathalie; Thibodeau, Jacques

Alternative pathways for MHC class I presentation: a new function for autophagy MHC I类呈现的替代途径: 自噬的新功能

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2011-03-10

PREAI

Chemali, Magali; Radtke, Kerstin; Desjardins, Michel; English, Luc

The endosomal proteome of macrophage and dendritic cells

PROTEOMICS

IF3.9

2011-01-31

OAAI

Duclos, Sophie; Clavarino, Giovanna; Rousserie, Gilles; Goyette, Guillaume; Boulais, Jonathan; Camossetto, Voahirana; Gatti, Evelina; LaBoissiere, Sylvie; Pierre, Philippe; Desjardins, Michel

研究方向