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L

Leah E. Cowen

university of toronto

61H指数
277论文数
1.5W被引数
收录论文 125
发表时间
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Compound Z247611722 Exhibits Antifungal Activity by Inhibiting Serine Palmitoyltransferase化合物Z247611722通过抑制丝氨酸棕榈酰转移酶发挥抗真菌活性
errNature Communications
IF15.7
err2026-09-15
err0
errOAAI
errJana Nysten; Wout Van Eynde; Yunjin Lee; Eliane Vanhoffelen; Giovanni Desiderati; Tine Van Win; Greetje Vande Velde; Arnout Voet; Nicole Robbins; Leah E. Cowen; Patrick Van Dijck
err分享
err收藏
Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi
errCell
IF42.5
err2026-01-01
err3
PREAI
errChen, Xuefei; Duan, H. Diessel; Hoy, Michael J.; Koteva, Kalinka; Spitzer, Michaela; Guitor, Allison K.; Puumala, Emily; Fiebig, Aline A.; Hu, Guanggan; Yiu, Bonnie; Chou, Sommer; Bian, Zhuyun; Choi, Yeseul; Guo, Amelia Bing Ya; Wang, Wenliang; Sun, Sheng; Robbins, Nicole; Averette, Anna Floyd; Cook, Michael A.; Truant, Ray; Macneil, Lesley T.; Brown, Eric D.; Kronstad, James W.; Coombes, Brian K.; Cowen, Leah E.; Heitman, Joseph; Li, Huilin; Wright, Gerard D.
err分享
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Sterol-C4-methyl-oxidase Erg251 governs Candida albicans hypoxic growth, commensalism and virulence甾醇-C4-甲基-氧化酶Erg251调控白色念珠菌低氧生长、共生状态和毒力
errNature Communications
IF15.7
err2025-12-12
err0
errOAAI
errZhongle Liu; Bonnie Yiu; Pauline Basso; Xuefei Chen; Disha Patel; Taylor Davie; Saif Hossain; Ci Fu; Linda S. Archambault; Dustin Duncan; Gerard D. Wright; Suzanne M. Noble; Nicole Robbins; Leah E. Cowen
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Identification and characterization of components of the Candida albicans inner kinetochore鉴定和表征白色念珠菌内着丝粒的组成部分
errGENETICS
IF5.1
err2025-10-01
err0
PREAI
errXiong, Emily H.; Fu, Ci; Lin, Zhen-Yuan; Wong, Cassandra J.; Nathwani, Kayla; Wang, Hansen; Gingras, Anne-Claude; Robbins, Nicole; Cowen, Leah E.
err分享
err收藏
Expansion of the functional genomics GRACE library reveals genes relevant for temperature-dependent fitness in Candida albicans功能基因组学GRACE库的扩展揭示了与白色念珠菌温度依赖性适应性相关的基因
errPLOS BIOLOGY
IF7.2
err2025-10-01
err0
PREAI
errFu, Ci; Xiong, Emily H.; Kupczok, Livia; Archambault, Linda S.; Wang, Timothy R. W.; Holleran, Caitlin; Carruthers-Lay, Duncan; Zhuang, Ting Xuan; Marcoccia, Sofia; Zhang, Haoyang; Chen, Kevin; Anderson, Daniel; Yiu, Bonnie; Liu, Zhongle; Herzel, Lydia; Robbins, Nicole; Cowen, Leah E.
err分享
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Author Correction: Colistin enhances caspofungin antifungal efficacy against Aspergillus fumigatus by modulating calcium homeostasis and stress responses作者更正：Colistin通过调节钙离子稳态和应激反应增强caspofungin对Aspergillus fumigatus的抗真菌效力
errNature Communications
IF15.7
err2025-08-15
err0
errOAAI
errLaura Cristina García Carnero; Xingyue Li; Patrícia Alves de Castro; Camila Figueiredo Pinzan; Jonatas Erick Maimoni Campanella; Iran Malavazi; Mami Yoshimura; Luis Alberto Vega Isuhuaylas; Yoko Yashiroda; Charles Boone; Nir Osherov; Sara Fallah; Taylor Davie; Nicole Robbins; Leah Cowen; Ling Lu; Thaila Fernanda dos Reis; Gustavo H. Goldman
err分享
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Adaptation of the tetracycline-repressible system for modulating the expression of essential genes in Cryptococcus neoformans四环素可调控系统在调节新型隐球菌必需基因表达中的应用
errMSPHERE
IF3.1
err2025-05-27
err0
errOAAI
errFu, Ci; Robbins, Nicole; Cowen, Leah E.
err分享
err收藏
Characterizing antimicrobial activity of environmental Streptomyces spp. and oral bacterial and fungal isolates from Canis familiaris and Felis catus
errMSPHERE
IF3.1
err2025-04-01
err0
errOAAI
errCowen, Audrey; Yiu, Bonnie; Fallah, Sara; Meyer, Kirsten J.; Puumala, Emily; Lee, Yunjin; Zubyk, Haley L.; Robbins, Nicole; Nodwell, Justin R.; MacAlpine, Jessie; Cowen, Leah E.
err分享
err收藏
Chemoproteomic Profiling of C. albicans for Characterization of Antifungal Kinase Inhibitors化学蛋白质组学分析用于鉴定抗真菌激酶抑制剂的C. albicans特征
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-20
err0
PREAI
errShirley, David J.; Nandakumar, Meganathan; Cabrera, Aurora; Yiu, Bonnie; Puumala, Emily; Liu, Zhongle; Robbins, Nicole; Whitesell, Luke; Smith, Jeffrey L.; Lyons, Scott; Mordant, Angie L.; Herring, Laura E.; Graves, Lee M.; Counago, Rafael M.; Drewry, David H.; Cowen, Leah E.
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The GPCR antagonist PPTN synergizes with caspofungin providing increased fungicidal activity against Aspergillus fumigatus
errMICROBIOLOGY SPECTRUM
IF3.8
err2025-03-01
err0
errOAAI
errdos Reis, Thaila Fernanda; Delbaje, Endrews; Pinzan, Camila Figueiredo; Bastos, Rafael; Ackloo, Suzanne; Fallah, Sara; Laflamme, Bradley; Robbins, Nicole; Cowen, Leah E.; Goldman, Gustavo H.
err分享
err收藏
Exploring the differential localization of protein kinase A isoforms in Candida albicans
errMSPHERE
IF3.1
err2025-02-25
err0
errOAAI
errHossain, Saif; Liu, Zhongle; Robbins, Nicole; Cowen, Leah E.
err分享
err收藏
The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence
errPLOS PATHOGENS
IF4.9
err2024-11-19
err3
errOAAI
errPeterson, Patricia P.; Choi, Jin-Tae; Fu, Ci; Cowen, Leah E.; Sun, Sheng; Bahn, Yong-Sun; Heitman, Joseph
err分享
err收藏
Naamidine A reveals a promising zinc-binding strategy for topical antifungal therapy
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-11-06
err0
PREAI
errPuumala, Emily; Nabeela, Sunna; Thornburg, Christopher C.; Grkovic, Tanja; Uppuluri, Priya; Whitesell, Luke; O'Keefe, Barry R.; Robbins, Nicole; Cowen, Leah E.
err分享
err收藏
The spliceosome impacts morphogenesis in the human fungal pathogen Candida albicans
errMBIO
IF4.7
err2024-08-14
err0
errOAAI
errLash, Emma; Maufrais, Corinne; Janbon, Guilhem; Robbins, Nicole; Herzel, Lydia; Cowen, Leah E.
err分享
err收藏
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase (vol 12, 6151, 2021)
errNATURE COMMUNICATIONS
IF15.7
err2024-08-01
err0
errOAAI
errMacAlpine, Jessie; Daniel-Ivad, Martin; Liu, Zhongle; Yano, Junko; Revie, Nicole M.; Todd, Robert T.; Stogios, Peter J.; Sanchez, Hiram; O'Meara, Teresa R.; Tompkins, Thomas A.; Savchenko, Alexei; Selmecki, Anna; Veri, Amanda O.; Andes, David R.; Fidel, Paul L.; Robbins, Nicole; Nodwell, Justin; Whitesell, Luke; Cowen, Leah E.
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err收藏
Functional genomic analysis of genes important for Candida albicans fitness in diverse environmental conditions
errCELL REPORTS
IF6.9
err2024-08-01
err0
errOAAI
errXiong, Emily H.; Zhang, Xiang; Yan, Huijuan; Ward, Henry N.; Lin, Zhen-Yuan; Wong, Cassandra J.; Fu, Ci; Gingras, Anne-Claude; Noble, Suzanne M.; Robbins, Nicole; Myers, Chad L.; Cowen, Leah E.
err分享
err收藏
Interdisciplinary approaches for the discovery of novel antifungals
errTrends in Molecular Medicine
IF13.8
err2024-08-01
err1
PREAI
errYiu, Bonnie; Robbins, Nicole; Cowen, Leah E.
err分享
err收藏
Reply to: Lactobacillus species do not produce 1-acetyl-β-carboline
errNATURE COMMUNICATIONS
IF15.7
err2024-08-01
err2
errOAAI
errMacAlpine, Jessie; Daniel-Ivad, Martin; Atere, Daniela; Laflamme, Bradley; Robbins, Nicole; Navarre, William W.; Nodwell, Justin; Whitesell, Luke; Cowen, Leah E.
err分享
err收藏
Cyprocide selectively kills nematodes via cytochrome P450 bioactivation
errNATURE COMMUNICATIONS
IF15.7
err2024-07-02
err1
errOAAI
errKnox, Jessica; Burns, Andrew R.; Cooke, Brittany; Cammalleri, Savina R.; Kitner, Megan; Ching, Justin; Castelli, Jack M. P.; Puumala, Emily; Snider, Jamie; Koury, Emily; Collins, J. B.; Geissah, Salma; Dowling, James J.; Andersen, Erik C.; Stagljar, Igor; Cowen, Leah E.; Lautens, Mark; Zasada, Inga; Roy, Peter J.
err分享
err收藏
A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans
errMICROBIOLOGY SPECTRUM
IF3.8
err2024-04-02
err3
errOAAI
errFallah, Sara; Duncan, Dustin; Reichl, Kyle D.; Smith, Michael J.; Wang, Wenyu; Porco Jr, John A.; Brown, Lauren E.; Whitesell, Luke; Robbins, Nicole; Cowen, Leah E.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
M
Michael A. Pfaller
H 指数: 151 · 论文数: 963
A
Arturo Casadevall
H 指数: 144 · 论文数: 1.5K
J
Joseph Heitman
H 指数: 134 · 论文数: 1.1K
S
Sergio Grinstein
H 指数: 131 · 论文数: 861
D
Daniel G. Anderson
H 指数: 128 · 论文数: 470
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