未登录 Chemoproteomic Profiling of C. albicans for Characterization of Antifungal Kinase Inhibitors 化学蛋白质组学分析用于鉴定抗真菌激酶抑制剂的C. albicans特征 Shirley, David J.; Nandakumar, Meganathan; Cabrera, Aurora; Yiu, Bonnie; Puumala, Emily; Liu, Zhongle; Robbins, Nicole; Whitesell, Luke; Smith, Jeffrey L.; Lyons, Scott; Mordant, Angie L.; Herring, Laura E.; Graves, Lee M.; Counago, Rafael M.; Drewry, David H.; Cowen, Leah E. 分享 收藏
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A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase (vol 12, 6151, 2021) MacAlpine, Jessie; Daniel-Ivad, Martin; Liu, Zhongle; Yano, Junko; Revie, Nicole M.; Todd, Robert T.; Stogios, Peter J.; Sanchez, Hiram; O'Meara, Teresa R.; Tompkins, Thomas A.; Savchenko, Alexei; Selmecki, Anna; Veri, Amanda O.; Andes, David R.; Fidel, Paul L.; Robbins, Nicole; Nodwell, Justin; Whitesell, Luke; Cowen, Leah E. 分享 收藏
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An HSF1-JMJD6-HSP feedback circuit promotes cell adaptation to proteotoxic stress Alasady, Milad J.; Koeva, Martina; Takagishi, Seesha R.; Segal, Dmitri; Amici, David R.; Smith, Roger S.; Ansel, Daniel J.; Lindquist, Susan; Whitesell, Luke; Bartom, Elizabeth T.; Taipale, Mikko; Mendillo, Marc L. 分享 收藏
A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans Fallah, Sara; Duncan, Dustin; Reichl, Kyle D.; Smith, Michael J.; Wang, Wenyu; Porco Jr, John A.; Brown, Lauren E.; Whitesell, Luke; Robbins, Nicole; Cowen, Leah E. 分享 收藏
Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl- b- thiophenylacrylamides exerts highly selective antifungal activity Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna; Fogal, Meea; Nigam, Akshatkumar; Johnson, Jarrod W.; Aspuru-Guzik, Alan; Shapiro, Rebecca S.; Uppuluri, Priya; Kalyaanamoorthy, Subha; Magolan, Jakob; Whitesell, Luke; Robbins, Nicole; Wright, Gerard D.; Cowen, Leah E. 分享 收藏
Respiration supports intraphagosomal filamentation and escape of Candida albicans from macrophages 呼吸支持巨噬细胞内白色念珠菌的丝状化和逃逸 Case, Nicola T.; Westman, Johannes; Hallett, Michael T.; Plumb, Jonathan; Farheen, Aiman; Maxson, Michelle E.; Macalpine, Jessie; Liston, Sean D.; Hube, Bernhard; Robbins, Nicole; Whitesell, Luke; Grinstein, Sergio; Cowen, Leah E. 分享 收藏
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Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity Iyer, Kali R.; Li, Sheena C.; Revie, Nicole M.; Lou, Jennifer W.; Duncan, Dustin; Fallah, Sara; Sanchez, Hiram; Skulska, Iwona; Usaj, Mojca Mattiazzi; Safizadeh, Hamid; Larsen, Brett; Wong, Cassandra; Aman, Ahmed; Kiyota, Taira; Yoshimura, Mami; Kimura, Hiromi; Hirano, Hiroyuki; Yoshida, Minoru; Osada, Hiroyuki; Gingras, Anne -Claude; Andes, David R.; Shapiro, Rebecca S.; Robbins, Nicole; Mazhab-Jafari, Mohammad T.; Whitesell, Luke; Yashiroda, Yoko; Yashiroda, Yoko; Boone, Charles; Cowen, Leah E. 分享 收藏
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The Trisubstituted Isoxazole MMV688766 Exerts Broad-Spectrum Activity against Drug-Resistant Fungal Pathogens through Inhibition of Lipid Homeostasis Puumala, Emily; Zaslaver, Olga; Chen, Amy; Duncan, Dustin; Fogal, Meea; Shapiro, Rebecca S.; Mazhab-Jafari, Mohammad T.; Whitesell, Luke; Montenegro-Burke, J. Rafael; Robbins, Nicole; Cowen, Leah E. 分享 收藏
Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation Revie, Nicole M.; Iyer, Kali R.; Maxson, Michelle E.; Zhang, Jiabao; Yan, Su; Fernandes, Caroline M.; Meyer, Kirsten J.; Chen, Xuefei; Skulska, Iwona; Fogal, Meea; Sanchez, Hiram; Hossain, Saif; Li, Sheena; Yashiroda, Yoko; Hirano, Hiroyuki; Yoshida, Minoru; Osada, Hiroyuki; Boone, Charles; Shapiro, Rebecca S.; Andes, David R.; Wright, Gerard D.; Nodwell, Justin R.; Del Poeta, Maurizio; Burke, Martin D.; Whitesell, Luke; Robbins, Nicole; Cowen, Leah E. 分享 收藏
Inhibiting C-4 Methyl Sterol Oxidase with Novel Diazaborines to Target Fungal Plant Pathogens Kim, Sang Hu; Steere, Luke; Zhang, Yong-Kang; McGregor, Cari; Hahne, Chris; Zhou, Yasheen; Liu, Chunliang; Cai, Yan; Zhou, Haibo; Chen, Xuefei; Puumala, Emily; Duncan, Dustin; Wright, Gerard D.; Liu, Tony; Whitesell, Luke; Cowen, Leah E. 分享 收藏
HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state HSF2与HSF1合作驱动对恶性状态至关重要的转录程序 Smith, Roger S.; Takagishi, Seesha R.; Amici, David R.; Metz, Kyle; Gayatri, Sitaram; Alasady, Milad J.; Wu, Yaqi; Brockway, Sonia; Taiberg, Stephanie L.; Khalatyan, Natalia; Taipale, Mikko; Santagata, Sandro; Whitesell, Luke; Lindquist, Susan; Savas, Jeffrey N.; Mendillo, Marc L. 分享 收藏
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance 酿酒酵母的适应性实验室进化突出了转录因子在真菌异源生物抗性中的作用 Ottilie, Sabine; Luth, Madeline R.; Hellemann, Erich; Goldgof, Gregory M.; Vigil, Eddy; Kumar, Prianka; Cheung, Andrea L.; Song, Miranda; Godinez-Macias, Karla P.; Carolino, Krypton; Yang, Jennifer; Lopez, Gisel; Abraham, Matthew; Tarsio, Maureen; LeBlanc, Emmanuelle; Whitesell, Luke; Schenken, Jake; Gunawan, Felicia; Patel, Reysha; Smith, Joshua; Love, Melissa S.; Williams, Roy M.; McNamara, Case W.; Gerwick, William H.; Ideker, Trey; Suzuki, Yo; Wirth, Dyann F.; Lukens, Amanda K.; Kane, Patricia M.; Cowen, Leah E.; Durrant, Jacob D.; Winzeler, Elizabeth A. 分享 收藏
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase MacAlpine, Jessie; Daniel-Ivad, Martin; Liu, Zhongle; Yano, Junko; Revie, Nicole M.; Todd, Robert T.; Stogios, Peter J.; Sanchez, Hiram; O'Meara, Teresa R.; Tompkins, Thomas A.; Savchenko, Alexei; Selmecki, Anna; Veri, Amanda O.; Andes, David R.; Fidel, Paul L.; Robbins, Nicole; Nodwell, Justin; Whitesell, Luke; Cowen, Leah E. 分享 收藏
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