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Type I IFN drives neutrophil swarming, impeding lung T cell-macrophage interactions and TB control I型IFN驱动中性粒细胞聚集，阻碍肺T细胞-巨噬细胞相互作用并影响结核病控制。J. Exp. Med. 222, e20250466 Branchett, William J.; Stavropoulos, Evangelos; Shields, Jessica; Al-Dibouni, Alaa; Cardoso, Marcos; Fernandes, Ana Isabel; Moreira-Teixeira, Lucia; Slawinski, Hubert; Mikolajczak, Anna; Rodgers, Angela; Saraiva, Margarida; O'Garra, Anne 分享 收藏
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Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis Alvarez-Martinez, Marisol; Cox, Luke S.; Pearson, Claire F.; Branchett, William J.; Chakravarty, Probir; Wu, Xuemei; Slawinski, Hubert; Al-Dibouni, Alaa; Samelis, Vasileios A.; Gabrysova, Leona; Priestnall, Simon L.; Suarez-Bonnet, Alejandro; Mikolajczak, Anna; Briscoe, James; Powrie, Fiona; O'Garra, Anne 分享 收藏
TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFa in LPS-stimulated macrophages (vol 121, pg 149, 2008) Rousseau, Simon; Papoutsopoulou, Matoula; Symons, Antony; Cook, Dorthe; Lucocq, John M.; Prescott, Alan R.; O'Garra, Anne; Ley, Steven C.; Cohen, Philip 分享 收藏
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Transcriptomic Characterization of Tuberculous Sputum Reveals a Host Warburg Effect and Microbial Cholesterol Catabolism Lai, Rachel P. J.; Cortes, Teresa; Marais, Suzaan; Rockwood, Neesha; Burke, Melissa L.; Garza-Garcia, Acely; Horswell, Stuart; Sesay, Abdul K.; O'Garra, Anne; Young, Douglas B.; Wilkinson, Robert J. 分享 收藏
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Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis Tabone, Olivier; Verma, Raman; Singhania, Akul; Chakravarty, Probir; Branchett, William J.; Graham, Christine M.; Lee, Jo; Trang, Tran; Reynier, Frederic; Leissner, Philippe; Kaiser, Karine; Rodrigue, Marc; Woltmann, Gerrit; Haldar, Pranabashis; O'Garra, Anne 分享 收藏
Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data Altman, Matthew C.; Rinchai, Darawan; Baldwin, Nicole; Toufiq, Mohammed; Whalen, Elizabeth; Garand, Mathieu; Kabeer, Basirudeen Syed Ahamed; Alfaki, Mohamed; Presnell, Scott R.; Khaenam, Prasong; Ayllon-Benitez, Aaron; Mougin, Fleur; Thebault, Patricia; Chiche, Laurent; Jourde-Chiche, Noemie; Phillips, J. Theodore; Klintmalm, Goran; O'Garra, Anne; Berry, Matthew; Bloom, Chloe; Wilkinson, Robert J.; Graham, Christine M.; Lipman, Marc; Lertmemongkolchai, Ganjana; Bedognetti, Davide; Thiebaut, Rodolphe; Kheradmand, Farrah; Mejias, Asuncion; Ramilo, Octavio; Palucka, Karolina; Pascual, Virginia; Banchereau, Jacques; Chaussabel, Damien 分享 收藏
Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure Branchett, William J.; Cook, James; Oliver, Robert A.; Bruno, Nicoletta; Walker, Simone A.; Stoelting, Helen; Mack, Matthias; O'Garra, Anne; Saglani, Sejal; Lloyd, Clare M. 分享 收藏
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis Moreira-Teixeira, Lucia; Stimpson, Philippa J.; Stavropoulos, Evangelos; Hadebe, Sabelo; Chakravarty, Probir; Ioannou, Marianna; Aramburu, Iker Valle; Herbert, Eleanor; Priestnall, Simon L.; Suarez-Bonnet, Alejandro; Sousa, Jeremy; Fonseca, Kaori L.; Wang, Qian; Vashakidze, Sergo; Rodriguez-Martinez, Paula; Vilaplana, Cristina; Saraiva, Margarida; Papayannopoulos, Venizelos; O'Garra, Anne 分享 收藏
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis Moreira-Teixeira, Lucia; Tabone, Olivier; Graham, Christine M.; Singhania, Akul; Stavropoulos, Evangelos; Redford, Paul S.; Chakravarty, Probir; Priestnall, Simon L.; Suarez-Bonnet, Alejandro; Herbert, Eleanor; Mayer-Barber, Katrin D.; Sher, Alan; Fonseca, Kaori L.; Sousa, Jeremy; Ca, Baltazar; Verma, Raman; Haldar, Pranabashis; Saraiva, Margarida; O'Garra, Anne 分享 收藏
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A T cell-myeloid IL-10 axis regulates pathogenic IFN-γ-dependent immunity in a mouse model of type 2-low asthma Branchett, William J.; Stolting, Helen; Oliver, Robert A.; Walker, Simone A.; Puttur, Franz; Gregory, Lisa G.; Gabrysova, Leona; Wilson, Mark S.; O'Garra, Anne; Lloyd, Clare M. 分享 收藏
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Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases 转录谱揭示了跨疾病的血液和组织中的I型和II型干扰素网络 Singhania, Akul; Graham, Christine M.; Gabrysova, Leona; Moreira-Teixeira, Lucia; Stavropoulos, Evangelos; Pitt, Jonathan M.; Chakravarty, Probir; Warnatsch, Annika; Branchett, William J.; Conejero, Laura; Lin, Jing-Wen; Davidson, Sophia; Wilson, Mark S.; Bancroft, Gregory; Langhorne, Jean; Frickel, Eva; Sesay, Abdul K.; Priestnall, Simon L.; Herbert, Eleanor; Ioannou, Marianna; Wang, Qian; Humphreys, Ian R.; Dodd, Jonathan; Openshaw, Peter J. M.; Mayer-Barber, Katrin D.; Jankovic, Dragana; Sher, Alan; Lloyd, Clare M.; Baldwin, Nicole; Chaussabel, Damien; Papayannopoulos, Venizelos; Wack, Andreas; Banchereau, Jacques F.; Pascual, Virginia M.; O'Garra, Anne 分享 收藏
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