Karen L. Maxwell - Publications, H-index & Citations

Karen L. Maxwell

university of toronto

46H指数

150论文数

9.2K被引数

收录论文 48

发表时间

Antiviral defence is a conserved function of diverse bacterial DNA glycosylases 抗病毒防御是多种细菌DNA糖基化酶的保守功能

Nature Microbiology

IF19.4

2026-08-06

PREAI

Landon J. Getz; Amy L. Qian; Y. Vivian Liu; Sam R. Fairburn; Mahnoor S. Butt; Yan-Jiun Lee; Peter R. Weigele; Karen L. Maxwell

Timing is everything: regulation of bacterial defences and phage counter-defences 时机至关重要：细菌防御机制及噬菌体反防御机制的调控

Current Opinion in Microbiology

IF7.5

2026-04-04

OAAI

Alyssa Vander Zee; Aakash Natarajan; Karen L Maxwell

How are bars and nightclubs in Scotland using extensions in late-night alcohol trading hours? Venue observation study 苏格兰的酒吧和夜总会如何利用延长后的夜间酒类交易时间？——场地观察研究

International Journal of Drug Policy

IF4.4

2026-02-26

OAAI

Carol Emslie; Karen Maxwell; Rachel O’Donnell; Gemma Mitchell; Megan Cook; Isabelle Uny; James Nicholls; Jim Lewsey; Emma McIntosh; Colin Angus; Andrea Mohan; Niamh Fitzgerald

A pore-forming antiphage defence is activated by oligomeric phage proteins 通过寡聚噬菌体蛋白激活成孔的抗噬菌体防御

Nature

IF48.5

2026-02-04

PREAI

Pramalkumar H. Patel; Matthew R. McCarthy; Véronique L. Taylor; Gregory B. Cole; Chi Zhang; Matthew M. Edghill; Landon J. Getz; Beatrice C. M. Fung; Trevor F. Moraes; Alan R. Davidson; Michael J. Norris; Karen L. Maxwell

A prophage-expressed type IV pilus component provides anti-phage defense 一个 prophage 表达的 IV 型菌毛组分提供抗噬菌体防御

Cell Reports

IF6.9

2026-01-01

OAAI

Kristina M. Sztanko; Taylor J. Ellison; Jill Greenlaw; Tatiana Lenskaia; P. Nathael Javorčík; Alexa D. Fitzpatrick; Karen L. Maxwell; Courtney K. Ellison; Alan R. Davidson

A Rapid Assay for Hepatitis C Virus RNA Detection Using Reverse-Transcription Loop-Mediated Isothermal Amplification-Coupled CRISPR-Cas12b-Based Strategy 使用逆转录环介导等温扩增偶联CRISPR-Cas12b-Based策略快速检测丙型肝炎病毒RNA

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2026-01-01

PREAI

Chowdhury, Avisha; Garcia, Bianca Garcia; Zahoor, Muhammad Atif; ElMawla, Nahla Fadl; Davidson, Alan R.; Wyatt, Haley D. M.; Maxwell, Karen L.; Mahassine, Ayoub; Gehring, Adam; Feld, Jordan J.

Results of TOR001: an open-label single patient study using targeted bacteriophage therapy for the treatment of a chronic urinary tract infection TOR001研究的结果：一项开放标签单病例研究，采用靶向噬菌体疗法治疗慢性尿路感染

International Journal of Antimicrobial Agents

IF4.6

2025-09-08

PREAI

Jonathan D. Cook; Payton B. Hooey; Keiko C. Salazar; Justin R. Clark; Umesh Jain; Carlos Fernando; Hanjeong Harvey; Alexander Cervantes; Stephanie Omagari; Udi Blankstein; Andrew M. Kropinski; Alan R. Davidson; Karen L. Maxwell; Lori L. Burrows; Austen L. Terwilliger; Anthony W. Maresso; Greg J. German

Prophages block cell surface receptors to preserve their viral progeny 原噬菌体阻断细胞表面受体以保存其病毒后代

Nature

IF48.5

2025-07-16

PREAI

Véronique L. Taylor; Pramalkumar H. Patel; Megha Shah; Ahmed Yusuf; Cayla M. Burk; Kristina M. Sztanko; Zemer Gitai; Alan R. Davidson; Matthias D. Koch; Karen L. Maxwell

A solution to the postantibiotic era: phages as precision medicine 后抗生素时代的解决方案：噬菌体作为精准医学

Current Opinion in Microbiology

IF7.5

2025-05-30

PREAI

Landon J Getz; Pramalkumar H Patel; Karen L Maxwell

Molecular basis of foreign DNA recognition by BREX anti-phage immunity system BREX抗噬菌体免疫系统对外源DNA识别的分子基础

NATURE COMMUNICATIONS

IF15.7

2025-02-20

OAAI

Drobiazko, Alena; Adams, Myfanwy C.; Skutel, Mikhail; Potekhina, Kristina; Kotovskaya, Oksana; Trofimova, Anna; Matlashov, Mikhail; Yatselenko, Daria; Maxwell, Karen L.; Severinov, Konstantin; Ghilarov, Dmitry; Isaev, Artem

Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication

MBIO

IF4.7

2025-02-01

OAAI

Fitzpatrick, Alexa D.; Taylor, Veronique L.; Patel, Pramalkumar H.; Faith, Dominick R.; Secor, Patrick R.; Maxwell, Karen L.

Integrons are anti-phage defence libraries in Vibrio parahaemolyticus 整合子是副溶血性弧菌中的抗噬菌体防御库。

NATURE MICROBIOLOGY

IF19.4

2025-01-27

PREAI

Getz, Landon J.; Fairburn, Sam R.; Liu, Y. Vivian; Qian, Amy L.; Maxwell, Karen L.

Anti-phage defence through inhibition of virion assembly

NATURE COMMUNICATIONS

IF15.7

2024-02-22

OAAI

Patel, Pramalkumar H.; Taylor, Veronique L.; Zhang, Chi; Getz, Landon J.; Fitzpatrick, Alexa D.; Davidson, Alan R.; Maxwell, Karen L.

Complete genomes and comparative analyses of Streptomyces phages that influence secondary metabolism and sporulation

SCIENTIFIC REPORTS

IF3.9

2023-06-17

OAAI

Kronheim, Sarah; Solomon, Ethan; Ho, Louis; Glossop, Michelle; Davidson, Alan R.; Maxwell, Karen L.

Prophages provide a rich source of antiphage defense systems

CURRENT OPINION IN MICROBIOLOGY

IF7.5

2023-06-01

PREAI

Patel, Pramalkumar H.; Maxwell, Karen L.

A Filamentous Bacteriophage Protein Inhibits Type IV Pili To Prevent Superinfection of Pseudomonas aeruginosa 丝状噬菌体蛋白抑制IV型菌毛以防止铜绿假单胞菌的重叠感染

MBIO

IF4.7

2022-02-22

OAAI

Schmidt, Amelia K.; Fitzpatrick, Alexa D.; Schwartzkopf, Caleb M.; Faith, Dominick R.; Jennings, Laura K.; Coluccio, Alison; Hunt, Devin J.; Michaels, Lia A.; Hargil, Aviv; Chen, Qingquan; Bollyky, Paul L.; Dorward, David W.; Wachter, Jenny; Rosa, Patricia A.; Maxwell, Karen L.; Secor, Patrick R.

A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa 噬菌体编码的抗激活剂抑制铜绿假单胞菌的quorum感应

MOLECULAR CELL

IF16.6

2021-02-01

OAAI

Shah, Megha; Taylor, Veronique L.; Bona, Diane; Tsao, Yvonne; Stanley, Sabrina Y.; Pimentel-Elardo, Sheila M.; McCallum, Matthew; Bondy-Denomy, Joseph; Howell, P. Lynne; Nodwell, Justin R.; Davidson, Alan R.; Moraes, Trevor F.; Maxwell, Karen L.

Retrons: Complementing CRISPR in Phage Defense

CRISPR JOURNAL

IF4

2020-08-01

PREAI

Maxwell, Karen L.

Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing

CELL REPORTS

IF6.9

2019-11-01

OAAI

Garcia, Bianca; Lee, Jooyoung; Edraki, Alireza; Hidalgo-Reyes, Yurima; Erwood, Steven; Mir, Aamir; Trost, Chantel N.; Seroussi, Uri; Stanley, Sabrina Y.; Cohn, Ronald D.; Claycomb, Julie M.; Sontheimer, Erik J.; Maxwell, Karen L.; Davidson, Alan R.

Bacterial twist to an antiviral defence

NATURE

IF48.5

2019-10-08

OAAI

Maxwell, Karen L.

研究方向