April Pawluk

University of Toronto

H指数:13

被引数:2,872

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A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation

组合域筛选平台揭示表观遗传效应因子在转录扰动中的相互作用

Nature Communications

IF15.7

2026-04-240

OAAI

Rewriting endogenous human transcripts with dual CRISPR-guided 3′ trans-splicing

用双重CRISPR指导的3 ′ 反式剪接重写内源性人类转录本

Cell Systems

IF7.7

2026-02-060

OAAI

Site-specific DNA insertion into the human genome with engineered recombinases

用工程重组酶将位点特异性DNA插入人类基因组

Nature Biotechnology

IF41.7

2025-11-060

OAAI

Bridge RNAs direct programmable recombination of target and donor DNA

Nature

IF48.5

2024-06-260

OAAI

Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting

CELL SYSTEMS

IF7.7

2023-12-0114

Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes

肠道微生物组的改变涉及炎症性关节炎表型的关键分类单元和代谢途径

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-07-2618

Thompson, Kelsey N. S.; Bonham, Kevin S. E.; Ilott, Nicholas E. J.; Britton, Graham J.; Colmenero, Paula J.; Bullers, Samuel J. J.; McIver, Lauren J.; Ma, Siyuan H.; Nguyen, Long H.; Filer, Andrew; Brough, India; Pearson, Claire; Moussa, Caroline; Kumar, Vinod H.; Lam, Lilian H. A.; Jackson, Matthew A.; Pawluk, April; Kiriakidis, Serafim R.; Taylor, Peter C.; Wedderburn, Lucy R. P.; Marsden, Brian R.; Young, Stephen P. J.; Littman, Dan R. G.; Faith, Jeremiah J.; Pratt, Arthur G.; Bowness, Paul; Raza, Karim; Powrie, Fiona; Huttenhower, Curtis

Potent Cas9 Inhibition in Bacterial and Human Cells by AcrllC4 and AcrllC5 Anti-CRISPR Proteins

AcrllC4和AcrllC5抗CRISPR蛋白在细菌和人类细胞中有效抑制Cas9

MBIO

IF4.7

2018-12-2185

OAAI

Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein

用噬菌体编码的抗CRISPR蛋白禁用i-e型crispr-cas核酸酶

MBIO

IF4.7

2017-12-2973

OAAI