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TREM2 supports neuronal protection and microglial reactivity without an effect on misfolded protein deposition in chronic neurodegenerative prion disease TREM2支持神经元保护和小胶质细胞反应性,但对慢性神经退行性朊病毒疾病中的错误折叠蛋白沉积无影响。 Carpanini, Sarah M.; Bradford, Barry M.; Alfieri, Alessio; Piccardo, Pedro; Monzon-Sandoval, Jimena; Brown, Deborah; Boyle, Aileen; Pokrovskaya, Aleksandra; Mabbott, Neil A.; Manson, Jean; McColl, Barry W. 分享 收藏
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The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology 与成年型白质脑病相关的显性激酶死亡Csf1r突变对脑发育和神经病理学的影响 Stables, Jennifer; Pal, Reiss; Bradford, Barry M.; Carter-Cusack, Dylan; Taylor, Isis; Pridans, Clare; Khan, Nemat; Woodruff, Trent M.; Irvine, Katharine M.; Summers, Kim M.; Mabbott, Neil A.; Hume, David A. 分享 收藏
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Microglia protect against age-associated brain pathologies Munro, David A. D.; Bestard-Cuche, Nadine; McQuaid, Conor; Chagnot, Audrey; Shabestari, Sepideh Kiani; Chadarevian, Jean Paul; Maheshwari, Upasana; Szymkowiak, Stefan; Morris, Kim; Mohammad, Mehreen; Corsinotti, Andrea; Bradford, Barry; Mabbott, Neil; Lennen, Ross J.; Jansen, Maurits A.; Pridans, Clare; McColl, Barry W.; Keller, Annika; Blurton-Jones, Mathew; Montagne, Axel; Williams, Anna; Priller, Josef 分享 收藏
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IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection (vol 14, 7070, 2023) Sinton, Matthew C.; Chandrasegaran, Praveena R. G.; Capewell, Paul; Cooper, Anneli; Girard, Alex; Ogunsola, John; Perona-Wright, Georgia; Ngoyi, Dieudonne; Kuispond, Nono; Bucheton, Bruno; Camara, Mamadou; Kajimura, Shingo; Benezech, Cecile; Mabbott, Neil A.; MacLeod, Annette; Quintana, Juan F. 分享 收藏
CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury Mckendrick, John G.; Jones, Gareth-Rhys; Elder, Sonia S.; Watson, Erin; T'Jonck, Wouter; Mercer, Ella; Magalhaes, Marlene S.; Rocchi, Cecilia; Hegarty, Lizi M.; Johnson, Amanda L.; Schneider, Christoph; Becher, Burkhard; Pridans, Clare; Mabbott, Neil; Liu, Zhaoyuan; Ginhoux, Florent; Bajenoff, Marc; Gentek, Rebecca; Bain, Calum C.; Emmerson, Elaine 分享 收藏
IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection IL-17信号传导对于控制慢性鼠布氏锥虫感染期间皮下脂肪组织动力学和寄生虫负担至关重要 Sinton, Matthew C.; Chandrasegaran, Praveena R. G.; Capewell, Paul; Cooper, Anneli; Girard, Alex; Ogunsola, John; Perona-Wright, Georgia; Ngoyi, Dieudonne; Kuispond, Nono; Bucheton, Bruno; Camara, Mamadou; Kajimura, Shingo; Benezech, Cecile; Mabbott, Neil A.; Macleod, Annette; Quintana, Juan F. 分享 收藏
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?d T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection ?d T细胞控制慢性布氏锥虫感染期间小鼠皮肤炎症和皮下脂肪消耗 Quintana, Juan F.; Sinton, Matthew C.; Chandrasegaran, Praveena; Lestari, Agatha Nabilla; Heslop, Rhiannon; Cheaib, Bachar; Ogunsola, John; Ngoyi, Dieudonne Mumba; Kuispond Swar, Nono-Raymond; Cooper, Anneli; Mabbott, Neil A.; Coffelt, Seth B.; Macleod, Annette 分享 收藏
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Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection 单细胞和空间转录组分析揭示了布氏锥虫感染期间大脑中的小胶质细胞-浆细胞串扰 Quintana, Juan F.; Chandrasegaran, Praveena; Sinton, Matthew C.; Briggs, Emma M.; Otto, Thomas D.; Heslop, Rhiannon; Bentley-Abbot, Calum; Loney, Colin; de Lecea, Luis; Mabbott, Neil A.; MacLeod, Annette 分享 收藏
Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia Shih, Barbara B.; Brown, Sarah M.; Barrington, Jack; Lefevre, Lucas; Mabbott, Neil A.; Priller, Josef; Thompson, Gerard; Lawrence, Alistair B.; McColl, Barry W. 分享 收藏
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