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A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo Xie, Stanley C.; Tai, Chia-Wei; Morton, Craig J.; Ma, Liting; Huang, Shih-Chung; Wittlin, Sergio; Du, Yawei; Hu, Yongbo; Dogovski, Con; Salimimarand, Mina; Griffin, Robert; England, Dylan; de la Cruz, Elisa; Deni, Ioanna; Yeo, Tomas; Burkhard, Anna Y.; Striepen, Josefine; Schindler, Kyra A.; Crespo, Benigno; Gamo, Francisco J.; Khandokar, Yogesh; Hutton, Craig A.; Rabie, Tayla; Birkholtz, Lyn-Marie; Famodimu, Mufuliat T.; Delves, Michael J.; Bolsher, Judith; Koolen, Karin M. J.; van der Laak, Rianne; Aguiar, Anna C. C.; Pereira, Dhelio B.; Guido, Rafael V. C.; Creek, Darren J.; Fidock, David A.; Dick, Lawrence R.; Brand, Stephen L.; Gould, Alexandra E.; Langston, Steven; Griffin, Michael D. W.; Tilley, Leann 分享 收藏
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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase Xie, Stanley C.; Wang, Yinuo; Morton, Craig J.; Metcalfe, Riley D.; Dogovski, Con; Pasaje, Charisse Flerida A.; Dunn, Elyse; Luth, Madeline R.; Kumpornsin, Krittikorn; Istvan, Eva S.; Park, Joon Sung; Fairhurst, Kate J.; Ketprasit, Nutpakal; Yeo, Tomas; Yildirim, Okan; Bhebhe, Mathamsanqa N.; Klug, Dana M.; Rutledge, Peter J.; Godoy, Luiz C.; Dey, Sumanta; De Souza, Mariana Laureano; Siqueira-Neto, Jair L.; Du, Yawei; Puhalovich, Tanya; Amini, Mona; Shami, Gerry; Loesbanluechai, Duangkamon; Nie, Shuai; Williamson, Nicholas; Jana, Gouranga P.; Maity, Bikash C.; Thomson, Patrick; Foley, Thomas; Tan, Derek S.; Niles, Jacquin C.; Han, Byung Woo; Goldberg, Daniel E.; Burrows, Jeremy; Fidock, David A.; Lee, Marcus C. S.; Winzeler, Elizabeth A.; Griffin, Michael D. W.; Todd, Matthew H.; Tilley, Leann 分享 收藏
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Plasmodium falciparum formins are essential for invasion and sexual stage development Collier, Sophie; Pietsch, Emma; Dans, Madeline; Ling, Dawson; Tavella, Tatyana A.; Lopaticki, Sash; Marapana, Danushka S.; Shibu, Mohini A.; Andrew, Dean; Tiash, Snigdha; McMillan, Paul J.; Gilson, Paul; Tilley, Leann; Dixon, Matthew W. A. 分享 收藏
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Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer's clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1 Carmo, Olivia M. S. W.; Shami, Gerald; Cox, Dezerae W.; Liu, Boyin; Blanch, Adam W.; Tiash, Snigdha; Tilley, Leann W.; Dixon, Matthew W. A. 分享 收藏
Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance Du, Yawei; Giannangelo, Carlo; He, Wei; Shami, Gerald J.; Zhou, Wenya; Yang, Tuo; Creek, Darren J.; Dogovski, Con; Li, Xinsong; Tilley, Leann 分享 收藏
Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites Liffner, Benjamin; Balbin, Juan Miguel; Shami, Gerald J.; Siddiqui, Ghizal; Strauss, Jan; Frolich, Sonja; Heinemann, Gary K.; Edwards, Ella May; Alder, Arne; Wichers, Jan Stephan; Creek, Darren J.; Tilley, Leann; Dixon, Matthew W. A.; Gilberger, Tim-Wolf; Wilson, Danny W. 分享 收藏
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Safety, infectivity and immunogenicity of a Chick for genetically attenuated blood-stage malaria updates vaccine 基因减毒血液阶段疟疾更新疫苗小鸡的安全性，传染性和免疫原性 Webster, Rebecca; Sekuloski, Silvana; Odedra, Anand; Woolley, Stephen; Jennings, Helen; Amante, Fiona; Trenholme, Katharine R.; Healer, Julie; Cowman, Alan F.; Eriksson, Emily M.; Sathe, Priyanka; Penington, Jocelyn; Blanch, Adam J.; Dixon, Matthew W. A.; Tilley, Leann; Duffy, Michael F.; Craig, Alister; Storm, Janet; Chan, Jo-Anne; Evans, Krystal; Papenfuss, Anthony T.; Schofield, Louis; Griffin, Paul; Barber, Bridget E.; Andrew, Dean; Boyle, Michelle J.; Rivera, Fabian de Labastida; Engwerda, Christian; McCarthy, James S. 分享 收藏
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome 设计具有体内抗恶性疟原虫的口服功效和对人蛋白酶体的选择性的蛋白酶体抑制剂 Xie, Stanley C.; Metcalfe, Riley D.; Mizutani, Hirotake; Puhalovich, Tanya; Hanssen, Eric; Morton, Craig J.; Du, Yawei; Dogovski, Con; Huang, Shih-Chung; Ciavarri, Jeffrey; Hales, Paul; Griffin, Robert J.; Cohen, Lawrence H.; Chuang, Bei-Ching; Wittlin, Sergio; Deni, Ioanna; Yeo, Tomas; Ward, Kurt E.; Barry, Daniel C.; Liu, Boyin; Gillett, David L.; Crespo-Fernandez, Benigno F.; Ottilie, Sabine; Mittal, Nimisha; Churchyard, Alisje; Ferguson, Daniel; Aguiar, Anna Caroline C.; Guido, Rafael V. C.; Baum, Jake; Hanson, Kirsten K.; Winzeler, Elizabeth A.; Gamo, Francisco-Javier; Fidock, David A.; Baud, Delphine; Parker, Michael W.; Brand, Stephen; Dick, Lawrence R.; Griffin, Michael D. W.; Gould, Alexandra E.; Tilley, Leann 分享 收藏
High Throughput Screening to Identify Selective and Nonpeptidomimetic Proteasome Inhibitors As Antimalarials 高通量筛选以鉴定选择性和非拟肽蛋白酶体抑制剂作为抗疟药 Mata-Cantero, Lydia; Xie, Stanley C.; Garcia, Mercedes; Coyle, Joanne; Fernandez, Raquel; Cortes Cabrera, Alvaro; Gillett, David L.; Crespo, Benigno; Gamo, Francisco-Javier; Fernandez, Esther; Tilley, Leann; Gomez-Lorenzo, Maria G. 分享 收藏
Non-canonical metabolic pathways in the malaria parasite detected by isotope-tracing metabolomics Cobbold, Simon A.; Tutor, Madel, V; Frasse, Philip; McHugh, Emma; Karnthaler, Markus; Creek, Darren J.; Odom John, Audrey; Tilley, Leann; Ralph, Stuart A.; McConville, Malcolm J. 分享 收藏
Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity 紫罗兰素诱导的伴侣系统崩溃是多阶段抗疟原虫活性的基础 Tavella, Tatyana Almeida; Melo da Silva, Noeli Soares; Spillman, Natalie; Andrade Vitor Kayano, Ana Carolina; Cassiano, Gustavo Capatti; Vasconcelos, Adrielle Ayumi; Camargo, Antonio Pedro; Baia da Silva, Djane Clarys; Fontinha, Diana; Salazar Alvarez, Luis Carlos; Ferreira, Leticia Tiburcio; Peralis Tomaz, Kaira Cristina; Neves, Bruno Junior; Almeida, Ludimila Dias; Bargieri, Daniel Youssef; Guimaraes de Lacerda, Marcus Vinicius; Lemos Cravo, Pedro Vitor; Sunnerhagen, Per; Prudencio, Miguel; Andrade, Carolina Horta; Pinto Lopes, Stefanie Costa; Carazzolle, Marcelo Falsarella; Tilley, Leann; Bilsland, Elizabeth; Borges, Julio Cesar; Maranhao Costa, Fabio Trindade 分享 收藏
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Role of Plasmodium falciparum Protein GEXPO7 in Maurer's Cleft Morphology, Knob Architecture, and P. falciparum EMP1 Trafficking McHugh, Emma; Carmo, Olivia M. S.; Blanch, Adam; Looker, Oliver; Liu, Boyin; Tiash, Snigdha; Andrew, Dean; Batinovic, Steven; Low, Andy J. Y.; Cho, Hyun-Jung; McMillan, Paul; Tilley, Leann; Dixon, Matthew W. A. 分享 收藏
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