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TCR-dependent CD8+T cell responses drive atherosclerotic plaque instability Noonan, Jonathan; Borcherding, Nicholas; Gherardin, Nicholas A.; Domke, Lisa M.; Watson, Anna; Huang, Angela; Barbaro-Wahl, Anastasia; Prijaya, Shania A.; Michla, Marcel; Huang, Yilu; Dayawansa, Nalin H.; Bongcaron, Viktoria; Walsh, Aidan; Sharma, Prerna; Kannelakis, Peter; Farrugia, Gabriella; Lee, Man-Kit Sam; Murphy, Andrew; Hsu, Ian; Pinto, Alexander; Kilby, Joseph; Wang, Xiaowei; Godfrey, Dale, I; Uldrich, Adam; Otto, Thomas D.; Bobik, Alex; Macleod, Megan K. L.; Vasudevan, Thodur; Kallies, Axel; Peter, Karlheinz 分享 收藏
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Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype Mclean, Florence E.; Omondi, Brian R.; Diallo, Nouhoum; Otoboh, Stanley; Kifude, Carolyne; Abdi, Abdirahman; Lim, Rivka; Otto, Thomas D.; Ghumra, Ashfaq; Rowe, J. Alexandra 分享 收藏
Genetic factors regulating Plasmodium falciparum gametocytogenesis identified by phenotypic screens Pires, Camilla V.; Chawla, Jyotsna; Sollelis, Lauriane; Oberstaller, Jenna; Zhang, Min; Wang, Chengqi; Gibbons, Justin; Rayner, Julian C.; Otto, Thomas D.; Marti, Matthias; Adams, John H. 分享 收藏
Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population Nyirenda, James; Hardy, Olympia M.; Silva Filho, Joao Da; Herder, Vanessa; Attipa, Charalampos; Ndovi, Charles; Siwombo, Memory; Namalima, Takondwa Rex; Suwedi, Leticia; Ilia, Georgios; Nyasulu, Watipenge; Ngulube, Thokozile; Nyirenda, Deborah; Mvaya, Leonard; Phiri, Joseph; Chasweka, Dennis; Eneya, Chisomo; Makwinja, Chikondi; Phiri, Chisomo; Ziwoya, Frank; Tembo, Abel; Makwangwala, Kingsley; Khoswe, Stanley; Banda, Peter; Morton, Ben; Hilton, Orla; Lawrence, Sarah; dos Reis, Monique Freire; Melo, Gisely Cardoso; de Lacerda, Marcus Vinicius Guimaraes; Trindade Maranhao Costa, Fabio; Monteiro, Wuelton Marcelo; Ferreira, Luiz Carlos de Lima; Johnson, Carla; Mcguinness, Dagmara; Jambo, Kondwani; Haley, Michael; Kumwenda, Benjamin; Palmarini, Massimo; Denno, Donna M.; Voskuijl, Wieger; Kamiza, Steve Bvuobvuo; Barnes, Kayla G.; Couper, Kevin; Marti, Matthias; Otto, Thomas D.; Moxon, Christopher A. 分享 收藏
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A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture Andradi-Brown, Clare; Wichers-Misterek, Jan Stephan; von Thien, Heidrun; Hoeppner, Yannick D.; Scholz, Judith A. M.; Hansson, Helle; Hocke, Emma Filtenborg; Gilberger, Tim Wolf; Duffy, Michael F.; Lavstsen, Thomas; Baum, Jake; Otto, Thomas D.; Cunnington, Aubrey J.; Bachmann, Anna 分享 收藏
Sterile protection against P. vivax malaria by repeated blood stage infection in the Aotus monkey model Obaldia III, Nicanor; Da Silva Filho, Joao Luiz; Nunez, Marlon; Glass, Katherine A.; Oulton, Tate; Achcar, Fiona; Wirjanata, Grennady; Duraisingh, Manoj; Felgner, Philip; Tetteh, Kevin K. A.; Bozdech, Zbynek; Otto, Thomas D.; Marti, Matthias 分享 收藏
MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites Wang, Chengqi; Dong, Yibo; Li, Chang; Oberstaller, Jenna; Zhang, Min; Gibbons, Justin; Pires, Camilla Valente; Xiao, Mianli; Zhu, Lei; Jiang, Rays H. Y.; Kim, Kami; Miao, Jun; Otto, Thomas D.; Cui, Liwang; Adams, John H.; Liu, Xiaoming 分享 收藏
A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum Simmons, Caroline; Gibbons, Justin; Wang, Chengqi; Pires, Camilla Valente; Zhang, Min; Siddiqui, Faiza; Oberstaller, Jenna; Casandra, Debora; Seyfang, Andreas; Cui, Liwang; Otto, Thomas D.; Adams, John H. 分享 收藏
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From contigs towards chromosomes: automatic improvement of long read assemblies (ILRA) 从重叠群到染色体: 长读组件 (ILRA) 的自动改进 Ruiz, Jose Luis; Reimering, Susanne; Escobar-Prieto, Juan David; Brancucci, Nicolas M. B.; Echeverry, Diego F.; Abdi, Abdirahman, I; Marti, Matthias; Gomez-Diaz, Elena; Otto, Thomas D. 分享 收藏
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Chemogenomic Profiling of a Plasmodium falciparum Transposon Mutant Library Reveals Shared Effects of Dihydroartemisinin and Bortezomib on Lipid Metabolism and Exported Proteins Pires, Camilla Valente; Oberstaller, Jenna; Wang, Chengqi; Casandra, Debora; Zhang, Min; Chawla, Jyotsna; Adapa, Swamy Rakesh; Otto, Thomas D.; Ferdig, Michael T.; Rayner, Julian C.; Jiang, Rays H. Y.; Adams, John H. 分享 收藏
Phenotypic Screens Identify Genetic Factors Associated with Gametocyte Development in the Human Malaria Parasite Plasmodium falciparum Chawla, Jyotsna; Goldowitz, Ilana; Oberstaller, Jenna; Zhang, Min; Pires, Camilla Valente; Navarro, Francesca; Sollelis, Lauriane; Wang, Chengqi C. Q.; Seyfang, Andreas; Dvorin, Jeffrey; Otto, Thomas D. D.; Rayner, Julian C. C.; Marti, Matthias; Adams, John H. H. 分享 收藏
Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum Simmons, Caroline F.; Gibbons, Justin; Zhang, Min; Oberstaller, Jenna; Pires, Camilla Valente; Casandra, Debora; Wang, Chengqi; Seyfang, Andreas; Otto, Thomas D.; Rayner, Julian C.; Adams, John H. 分享 收藏
Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection 单细胞和空间转录组分析揭示了布氏锥虫感染期间大脑中的小胶质细胞-浆细胞串扰 Quintana, Juan F.; Chandrasegaran, Praveena; Sinton, Matthew C.; Briggs, Emma M.; Otto, Thomas D.; Heslop, Rhiannon; Bentley-Abbot, Calum; Loney, Colin; de Lecea, Luis; Mabbott, Neil A.; MacLeod, Annette 分享 收藏