Cantoni, Diego; Murray, Matthew J.; Kalemera, Mphatso D.; Dicken, Samuel J.; Stejskal, Lenka; Brown, Georgina; Lytras, Spyros; Coey, Jonathon D.; McKenna, James; Bridgett, Stephen; Simpson, David; Fairley, Derek; Thorne, Lucy G.; Reuschl, Ann-Kathrin; Forrest, Calum; Ganeshalingham, Maaroothen; Muir, Luke; Palor, Machaela; Jarvis, Lisa; Willett, Brian; Power, Ultan F.; McCoy, Laura E.; Jolly, Clare; Towers, Greg J.; Doores, Katie J.; Robertson, David L.; Shepherd, Adrian J.; Reeves, Matthew B.; Bamford, Connor G. G.; Grove, Joe

Preclinical and randomized phase I studies of plitidepsin in adults with COVID-19

LIFE SCIENCE ALLIANCE

IF2.9

2022-01-1030

Varona, Jose F.; Landete, Pedro; Lopez-Martin, Jose A.; Estrada, Vicente; Paredes, Roger; Guisado-Vasco, Pablo; Fernandez de Orueta, Lucia; Torralba, Miguel; Fortun, Jesus; Vates, Roberto; Barberan, Jose; Clotet, Bonaventura; Ancochea, Julio; Carnevali, Daniel; Cabello, Noemi; Porras, Lourdes; Gijon, Paloma; Monereo, Alfonso; Abad, Daniel; Zuniga, Sonia; Sola, Isabel; Rodon, Jordi; Vergara-Alert, Julia; Izquierdo-Useros, Nuria; Fudio, Salvador; Jose Pontes, Maria; de Rivas, Beatriz; Giron de Velasco, Patricia; Nieto, Antonio; Gomez, Javier; Aviles, Pablo; Lubomirov, Rubin; Belgrano, Alvaro; Sopesen, Belen; White, Kris M.; Rosales, Romel; Yildiz, Soner; Reuschl, Ann-Kathrin; Thorne, Lucy G.; Jolly, Clare; Towers, Greg J.; Zuliani-Alvarez, Lorena; Bouhaddou, Mehdi; Obernier, Kirsten; McGovern, Briana L.; Rodriguez, M. Luis; Enjuanes, Luis; Fernandez-Sousa, Jose M.; Krogan, Nevan J.; Jimeno, Jose M.; Garcia-Sastre, Adolfo

Evolution of enhanced innate immune evasion by SARS-CoV-2

Nature

IF48.5

2021-12-230

OAAI

Lucy G. Thorne; Mehdi Bouhaddou; Ann-Kathrin Reuschl; Lorena Zuliani-Alvarez; Ben Polacco; Adrian Pelin; Jyoti Batra; Matthew V. X. Whelan; Myra Hosmillo; Andrea Fossati; Roberta Ragazzini; Irwin Jungreis; Manisha Ummadi; Ajda Rojc; Jane Turner; Marie L. Bischof; Kirsten Obernier; Hannes Braberg; Margaret Soucheray; Alicia Richards; Kuei-Ho Chen; Bhavya Harjai; Danish Memon; Joseph Hiatt; Romel Rosales; Briana L. McGovern; Aminu Jahun; Jacqueline M. Fabius; Kris White; Ian G. Goodfellow; Yasu Takeuchi; Paola Bonfanti; Kevan Shokat; Natalia Jura; Klim Verba; Mahdad Noursadeghi; Pedro Beltrao; Manolis Kellis; Danielle L. Swaney; Adolfo García-Sastre; Clare Jolly; Greg J. Towers; Nevan J. Krogan

Murine norovirus virulence factor 1 (VF1) protein contributes to viral fitness during persistent infection

JOURNAL OF GENERAL VIROLOGY

IF4.3

2021-09-234

OAAI

SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation

RIG-I和MDA5的SARS-CoV-2感应将上皮感染与巨噬细胞炎症联系起来

EMBO JOURNAL

IF8.3

2021-07-02142

OAAI

HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport

ELIFE

IF0

2020-12-1036

Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells

CELL STEM CELL

IF20.4

2018-12-0193

OAAI

Targeting macrophage- and intestinal epithelial cell-specific microRNAs against norovirus restricts replication in vivo

JOURNAL OF GENERAL VIROLOGY

IF4.3

2018-12-014

The First Norovirus Longitudinal Seroepidemiological Study From Sub-Saharan Africa Reveals High Seroprevalence of Diverse Genotypes Associated With Host Susceptibility Factors

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2018-04-1820

OAAI

Are evolution and the intracellular innate immune System Key Determinants in HIV Transmission?

FRONTIERS IN IMMUNOLOGY

IF5.9

2017-10-0625

OAAI

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2

MBIO

IF4.7

2017-09-0651

OAAI

Nitazoxanide Is an Ineffective Treatment of Chronic Norovirus in Patients With X-Linked Agammaglobulinemia and May Yield False-Negative Polymerase Chain Reaction Findings in Stool Specimens Reply

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2017-01-251

OAAI

Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo

MSPHERE

IF3.1

2016-10-2635

OAAI

Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases

塞拉利昂埃博拉病毒的快速爆发测序确定了与零星病例相关的传播链

VIRUS EVOLUTION

IF4

2016-06-22108

OAAI

Arias, Armando; Watson, Simon J.; Asogun, Danny; Tobin, Ekaete Alice; Lu, Jia; Phan, My V. T.; Jah, Umaru; Wadoum, Raoul Emeric Guetiya; Meredith, Luke; Thorne, Lucy; Caddy, Sarah; Tarawalie, Alimamy; Langat, Pinky; Dudas, Gytis; Faria, Nuno R.; Dellicour, Simon; Kamara, Abdul; Kargbo, Brima; Kamara, Brima Osaio; Gevao, Sahr; Cooper, Daniel; Newport, Matthew; Horby, Peter; Dunning, Jake; Sahr, Foday; Brooks, Tim; Simpson, Andrew J. H.; Groppelli, Elisabetta; Liu, Guoying; Mulakken, Nisha; Rhodes, Kate; Akpablie, James; Yoti, Zabulon; Lamunu, Margaret; Vitto, Esther; Otim, Patrick; Owilli, Collins; Boateng, Isaac; Okoror, Lawrence; Omomoh, Emmanuel; Oyakhilome, Jennifer; Omiunu, Racheal; Yemisis, Ighodalo; Adomeh, Donatus; Ehikhiametalor, Solomon; Akhilomen, Patience; Aire, Chris; Kurth, Andreas; Cook, Nicola; Baumann, Jan; Gabriel, Martin; Woelfel, Roman; Di Caro, Antonino; Carroll, Miles W.; Guenther, Stephan; Redd, John; Naidoo, Dhamari; Pybus, Oliver G.; Rambaut, Andrew; Kellam, Paul; Goodfellow, Ian; Cotten, Matthew

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

PLOS MEDICINE

IF9.9

2016-04-19138

OAAI

Dunning, Jake; Sahr, Foday; Rojek, Amanda; Gannon, Fiona; Carson, Gail; Idriss, Baimba; Massaquoi, Thomas; Gandi, Regina; Joseph, Sebatu; Osman, Hassan K.; Brooks, Timothy J. G.; Simpson, Andrew J. H.; Goodfellow, Ian; Thorne, Lucy; Arias, Armando; Merson, Laura; Castle, Lyndsey; Howell-Jones, Rebecca; Pardinaz-Solis, Raul; Hope-Gill, Benjamin; Ferri, Mauricio; Grove, Jennifer; Kowalski, Mark; Stepniewska, Kasia; Lang, Trudie; Whitehead, John; Olliaro, Piero; Samai, Mohammed; Horby, Peter W.

Lucy Thorne

个人简介

教育背景

工作经历

荣誉奖项

研究方向