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Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease models Crouchet, Emilie; Schaeffer, Eugenie; Oudot, Marine A.; Moehlin, Julien; Gadenne, Cloe; Juhling, Frank; El Saghire, Hussein; Fujiwara, Naoto; Zhu, Shijia; Rasha, Fahmida Akter; Durand, Sarah C.; Charlot, Anouk; Ponsolles, Clara; Martin, Romain; Brignon, Nicolas; Del Zompo, Fabio; Meiss-Heydmann, Laura; Parnot, Marie; Hamdane, Nourdine; Heide, Danijela; Hetzer, Jenny; Heikenwalder, Mathias; Felli, Emanuele; Pessaux, Patrick; Pochet, Nathalie; Zoll, Joffrey; Cunniff, Brian; Hoshida, Yujin; Mailly, Laurent; Baumert, Thomas F.; Schuster, Catherine 分享 收藏
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Cell Segmentation With Globally Optimized Boundaries (CSGO): A Deep Learning Pipeline for Whole-Cell Segmentation in Hematoxylin-and-Eosin-Stained Tissues Gu, Zifan; Wang, Shidan; Rong, Ruichen; Zhao, Zhuo; Wu, Fangjiang; Zhou, Qin; Wen, Zhuoyu; Chi, Zhikai; Fang, Yisheng; Peng, Yan; Jia, Liwei; Chen, Mingyi; Yang, Donghan M.; Hoshida, Yujin; Xie, Yang; Xiao, Guanghua 分享 收藏
Spatial omics-based machine learning algorithms for the early detection of hepatocellular carcinoma Wang, Mengjun; Grauzam, Stephane; Bayram, Muhammed Furkan; Dressman, James; Delacourt, Andrew; Blaschke, Calvin; Liang, Hongyan; Scott, Danielle; Huffman, Gray; Black, Alyson; Ochoa-Rios, Shaaron; Lewin, David; Angel, Peggi M.; Drake, Richard R.; Ball, Lauren; Bethard, Jennifer; Castellino, Stephen; Kono, Yuko; Kubota, Naoto; Hoshida, Yujin; Quirk, Lisa; Yopp, Adam; Gopal, Purva; Singal, Amit; Mehta, Anand S. 分享 收藏
Post-translational modifications drive the effects of HMGB1 in alcohol-associated liver disease Ge, Xiaodong; Subramaniyam, Nithyananthan; Song, Zhuolun; Desert, Romain; Han, Hui; Das, Sukanta; Komakula, Sai Santosh Babu; Wang, Chao; Lantvit, Daniel; Ge, Zhiyan; Hoshida, Yujin; Nieto, Natalia 分享 收藏
HCC spatial transcriptomic profiling reveals significant and potentially targetable cancer-endothelial interactions Lu, Chenyue; Pankaj, Amaya; Raabe, Michael; Nawrocki, Cole; Liu, Ann; Xu, Nova; Patel, Bidish K.; Emmett, Matthew J.; Coley, Avril K.; Ferrone, Cristina R.; Deshpande, Vikram; Bhan, Irun; Hoshida, Yujin; Ting, David T.; Aryee, Martin J.; Franses, Joseph W. 分享 收藏
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PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer Zhu, Min; Wang, Yunguan; Lu, Tianshi; Guo, Jason; Li, Lin; Hsieh, Meng-Hsiung; Gopal, Purva; Han, Yi; Fujiwara, Naoto; Wallace, Darren P.; Yu, Alan S. L.; Fang, Xiangyi; Ransom, Crystal; Verschleisser, Sara; Hsiehchen, David; Hoshida, Yujin; Singal, Amit G.; Yopp, Adam; Wang, Tao; Zhu, Hao 分享 收藏
The Spatial Extracellular Proteomic Tumor Microenvironment Distinguishes Molecular Subtypes of Hepatocellular Carcinoma Macdonald, Jade K.; Taylor, Harrison B.; Wang, Mengjun; Delacourt, Andrew; Edge, Christin; Lewin, David N.; Kubota, Naoto; Fujiwara, Naoto; Rasha, Fahmida; Marquez, Cesia A.; Ono, Atsushi; Oka, Shiro; Chayama, Kazuaki; Lewis, Sara; Taouli, Bachir; Schwartz, Myron; Fiel, M. Isabel; Drake, Richard R.; Hoshida, Yujin; Mehta, Anand S.; Angel, Peggi M. 分享 收藏
Aspirin for Metabolic Dysfunction-Associated Steatotic Liver Disease Without Cirrhosis A Randomized Clinical Trial Simon, Tracey G.; Wilechansky, Robert M.; Stoyanova, Stefania; Grossman, Alessandra; Dichtel, Laura E.; Lauer, Georg M.; Miller, Karen K.; Hoshida, Yujin; Corey, Kathleen E.; Loomba, Rohit; Chung, Raymond T.; Chan, Andrew T. 分享 收藏
The phosphatidylserine targeting antibody bavituximab plus pembrolizumab in unresectable hepatocellular carcinoma: a phase 2 trial Hsiehchen, David; Beg, Muhammad S.; Kainthla, Radhika; Lohrey, Jay; Kazmi, Syed M.; Khosama, Leticia; Maxwell, Mary Claire; Kline, Heather; Katz, Courtney; Hassan, Asim; Kubota, Naoto; Siglinsky, Ellen; Pillai, Anil K.; Youssoufian, Hagop; Mockbee, Colleen; Culm, Kerry; Uhlik, Mark; Benjamin, Laura; Brekken, Rolf A.; Ahn, Chul; Singal, Amit G.; Zhu, Hao; Hoshida, Yujin; Yopp, Adam C. 分享 收藏
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Fibroblast growth factor inhibition by molecular-targeted agents mitigates immunosuppressive tissue microenvironment in hepatocellular carcinoma Suzuki, Hiroyuki; Iwamoto, Hideki; Tanaka, Toshimitsu; Sakaue, Takahiko; Imamura, Yasuko; Masuda, Atsutaka; Nakamura, Toru; Koga, Hironori; Hoshida, Yujin; Kawaguchi, Takumi 分享 收藏
Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer Santasusagna, Sandra; Zhu, Shijia; Jawalagatti, Vijayakumar; Carceles-Cordon, Marc; Ertel, Adam; Garcia-Longarte, Saioa; Song, Won-Min; Fujiwara, Naoto; Li, Peiyao; Mendizabal, Isabel; Petrylak, Daniel P.; Kelly, William Kevin; Reddy, E. Premkumar; Wang, Liguo; Schiewer, Matthew J.; Lujambio, Amaia; Karnes, Jeffrey; Knudsen, Karen E.; Cordon-Cardo, Carlos; Dong, Haidong; Huang, Haojie; Carracedo, Arkaitz; Hoshida, Yujin; Rodriguez-Bravo, Veronica; Domingo-Domenech, Josep 分享 收藏
International Liver Cancer Association (ILCA) white paper on hepatocellular carcinoma risk stratification and surveillance Singal, Amit G.; Sanduzzi-Zamparelli, Marco; Nahon, Pierre; Ronot, Maxime; Hoshida, Yujin; Rich, Nicole; Reig, Maria; Vilgrain, Valerie; Marrero, Jorge; Llovet, Josep M.; Parikh, Neehar D.; Villanueva, Augusto 分享 收藏