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C

Collin M. Blakely

University of California San Francisco
H指数:38
被引数:8,549

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Targeting WEE1 to Overcome ARID1A Mutation-Driven Osimertinib Resistance in EGFR-Mutant Lung Cancer

靶向WEE1以克服ARID1A突变驱动的奥希替尼耐药性在EGFR突变型肺癌中

Journal of Thoracic Oncology
IF20.8
2025-06-130
OAAI
Koji Fukuda; Shigeki Nanjo; Shinji Takeuchi; Turja Chakrabarti; Tyiesha Brown; Sharon Wesley Dev Sahadevan; Sachiko Arai; Shigeki Sato; Hiroshi Kotani; Akihiro Nishiyama; Hiroyuki Sakaguchi; Koushiro Ohtsubo; Hiroaki Taniguchi; Collin M. Blakely; Trever G. Bivona; Seiji Yano
Sitravatinib in patients with solid tumors selected by molecular alterations: results from a Phase Ib study

通过分子改变选择的实体瘤患者的sitratinib: Ib期研究的结果

FUTURE ONCOLOGY
IF2.6
2024-11-080
OAAI
Bazhenova, Lyudmila; Kim, Dong-Wan; Cho, Byoung Chul; Goel, Sanjay; Heist, Rebecca; Werner, Theresa L.; Eaton, Keith D.; Wang, Judy S.; Pant, Shubham; Adkins, Douglas R.; Blakely, Collin M.; Yan, Xiaohong; Neuteboom, Saskia; Christensen, James G.; Chao, Richard; Bauer, Todd
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

CTLA4阻断消除KEAP1/STK11-related对PD-(L)1抑制剂的抗性

Nature
IF48.5
2024-10-090
OAAI
Ferdinandos Skoulidis; Haniel A. Araujo; Minh Truong Do; Yu Qian; Xin Sun; Ana Galan-Cobo; John T. Le; Meagan Montesion; Rachael Palmer; Nadine Jahchan; Joseph M. Juan; Chengyin Min; Yi Yu; Xuewen Pan; Kathryn C. Arbour; Natalie Vokes; Stephanie T. Schmidt; David Molkentine; Dwight H. Owen; Regan Memmott; Pradnya D. Patil; Melina E. Marmarelis; Mark M. Awad; Joseph C. Murray; Jessica A. Hellyer; Justin F. Gainor; Anastasios Dimou; Christine M. Bestvina; Catherine A. Shu; Jonathan W. Riess; Collin M. Blakely; Chad V. Pecot; Laura Mezquita; Fabrizio Tabbó; Matthias Scheffler; Subba Digumarthy; Meghan J. Mooradian; Adrian G. Sacher; Sally C. M. Lau; Andreas N. Saltos; Julia Rotow; Rocio Perez Johnson; Corinne Liu; Tyler Stewart; Sarah B. Goldberg; Jonathan Killam; Zenta Walther; Kurt Schalper; Kurtis D. Davies; Mark G. Woodcock; Valsamo Anagnostou; Kristen A. Marrone; Patrick M. Forde; Biagio Ricciuti; Deepti Venkatraman; Eliezer M. Van Allen; Amy L. Cummings; Jonathan W. Goldman; Hiram Shaish; Melanie Kier; Sharyn Katz; Charu Aggarwal; Ying Ni; Joseph T. Azok; Jeremy Segal; Lauren Ritterhouse; Joel W. Neal; Ludovic Lacroix; Yasir Y. Elamin; Marcelo V. Negrao; Xiuning Le; Vincent K. Lam; Whitney E. Lewis; Haley N. Kemp; Brett Carter; Jack A. Roth; Stephen Swisher; Richard Lee; Teng Zhou; Alissa Poteete; Yifan Kong; Tomohiro Takehara; Alvaro Guimaraes Paula; Edwin R. Parra Cuentas; Carmen Behrens; Ignacio I. Wistuba; Jianjun Zhang; George R. Blumenschein; Carl Gay; Lauren A. Byers; Don L. Gibbons; Anne Tsao; J. Jack Lee; Trever G. Bivona; D. Ross Camidge; Jhannelle E. Gray; Natasha B. Leighl; Benjamin Levy; Julie R. Brahmer; Marina C. Garassino; David R. Gandara; Edward B. Garon; Naiyer A. Rizvi; Giorgio Vittorio Scagliotti; Jürgen Wolf; David Planchard; Benjamin Besse; Roy S. Herbst; Heather A. Wakelee; Nathan A. Pennell; Alice T. Shaw; Pasi A. Jänne; David P. Carbone; Matthew D. Hellmann; Charles M. Rudin; Lee Albacker; Helen Mann; Zhou Zhu; Zhongwu Lai; Ross Stewart; Solange Peters; Melissa L. Johnson; Kwok K. Wong; Alan Huang; Monte M. Winslow; Michael J. Rosen; Ian P. Winters; Vassiliki A. Papadimitrakopoulou; Tina Cascone; Philip Jewsbury; John V. Heymach
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer
NATURE COMMUNICATIONS
IF15.7
2024-05-0310
OAAI
Haderk, Franziska; Chou, Yu-Ting; Cech, Lauren; Fernandez-Mendez, Celia; Yu, Johnny; Olivas, Victor; Meraz, Ismail M.; Rabago, Dora Barbosa; Kerr, D. Lucas; Gomez, Carlos; Allegakoen, David V.; Guan, Juan; Shah, Khyati N.; Herrington, Kari A.; Gbenedio, Oghenekevwe M.; Nanjo, Shigeki; Majidi, Mourad; Tamaki, Whitney; Pourmoghadam, Yashar K.; Rotow, Julia K.; McCoach, Caroline E.; Riess, Jonathan W.; Gutkind, J. Silvio; Tang, Tracy T.; Post, Leonard; Huang, Bo; Santisteban, Pilar; Goodarzi, Hani; Bandyopadhyay, Sourav; Kuo, Calvin J.; Roose, Jeroen P.; Wu, Wei; Blakely, Collin M.; Roth, Jack A.; Bivona, Trever G.
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors

PERCEPTION使用肿瘤的单细胞转录组学预测患者对治疗的反应和抵抗力

NATURE CANCER
IF28.5
2024-04-188
OA
Sinha, Sanju; Vegesna, Rahulsimham; Mukherjee, Sumit; Kammula, Ashwin V.; Dhruba, Saugato Rahman; Wu, Wei; Kerr, D. Lucas; Nair, Nishanth Ulhas; Jones, Matthew G.; Yosef, Nir; Stroganov, Oleg V.; Grishagin, Ivan; Aldape, Kenneth D.; Blakely, Collin M.; Jiang, Peng; Thomas, Craig J.; Benes, Cyril H.; Bivona, Trever G.; Schaeffer, Alejandro A.; Ruppin, Eytan
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance
NATURE GENETICS
IF31.8
2023-12-0419
OAAI
Caswell, Deborah R.; Gui, Philippe; Mayekar, Manasi K.; Law, Emily K.; Pich, Oriol; Bailey, Chris; Boumelha, Jesse; Kerr, D. Lucas; Blakely, Collin M.; Manabe, Tadashi; Martinez-Ruiz, Carlos; Bakker, Bjorn; Villcas, Juan De Dios Palomino; I. Vokes, Natalie; Dietzen, Michelle; Angelova, Mihaela; Gini, Beatrice; Tamaki, Whitney; Allegakoen, Paul; Wu, Wei; Humpton, Timothy J.; Hill, William; Tomaschko, Mona; Lu, Wei-Ting; Haderk, Franziska; Al Bakir, Maise; Nagano, Ai; Gimeno-Valiente, Francisco; Trecesson, Sophie de Carne; Vendramin, Roberto; Barbe, Vittorio; Mugabo, Miriam; Weeden, Clare E.; Rowan, Andrew; McCoach, Caroline E.; Almeida, Bruna; Green, Mary; Gomez, Carlos; Nanjo, Shigeki; Barbosa, Dora; Moore, Chris; Przewrocka, Joanna; Black, James R. M.; Gronroos, Eva; Suarez-Bonnet, Alejandro; Priestnall, Simon L.; Zverev, Caroline; Lighterness, Scott; Cormack, James; Olivas, Victor; Cech, Lauren; Andrews, Trisha; Rule, Brandon; Jiao, Yuwei; Zhang, Xinzhu; Ashford, Paul; Durfee, Cameron; Venkatesan, Subramanian; Temiz, Nuri Alpay; Tan, Lisa; Larson, Lindsay K.; Argyris, Prokopios P.; Brown, William L.; Yu, Elizabeth A.; Rotow, Julia K.; Guha, Udayan; Roper, Nitin; Yu, Johnny; Vogel, Rachel I.; Thomas, Nicholas J.; Marra, Antonio; Selenica, Pier; Yu, Helena; Bakhoum, Samuel F.; Chew, Su Kit; Reis-Filho, Jorge S.; Jamal-Hanjani, Mariam; Vousden, Karen H.; McGranahan, Nicholas; Van Allen, Eliezer M.; Kanu, Nnennaya; Harris, Reuben S.; Downward, Julian; Bivona, Trever G.; Swanton, Charles
Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC

KRASG12C抑制剂在晚期NSCLC中的疗效和作用

CANCER DISCOVERY
IF33.3
2023-04-1765
OA
Negrao, Marcelo V.; Araujo, Haniel A.; Lamberti, Giuseppe; Cooper, Alissa J.; Akhave, Neal S.; Zhou, Teng; Delasos, Lukas; Hicks, J. Kevin; Aldea, Mihaela; Minuti, Gabriele; Hines, Jacobi; Aredo, Jacqueline V.; Dennis, Michael J.; Chakrabarti, Turja; Scott, Susan C.; Bironzo, Paolo; Scheffler, Matthias; Christopoulos, Petros; Stenzinger, Albrecht; Riess, Jonathan W.; Kim, So Yeon; Goldberg, Sarah B.; Li, Mingjia; Wang, Qi; Qing, Yun; Ni, Ying; Do, Minh Truong; Lee, Richard; Ricciuti, Biagio; Alessi, Joao Victor; Wang, Jing; Resuli, Blerina; Landi, Lorenza; Tseng, Shu-Chi; Nishino, Mizuki; Digumarthy, Subba R.; Rinsurongkawong, Waree; Rinsurongkawong, Vadeerat; Vaporciyan, Ara A.; Blumenschein, George R., Jr.; Zhang, Jianjun; Owen, Dwight H.; Blakely, Collin M.; Mountzios, Giannis; Shu, Catherine A.; Bestvina, Christine M.; Garassino, Marina Chiara; Marrone, Kristen A.; Gray, Jhanelle E.; Patel, Sandip Pravin; Cummings, Amy L.; Wakelee, Heather A.; Wolf, Juergen; Scagliotti, Giorgio Vittorio; Cappuzzo, Federico; Barlesi, Fabrice; Patil, Pradnya D.; Drusbosky, Leylah; Gibbons, Don L.; Meric-Bernstam, Funda; Lee, J. Jack; Heymach, John V.; Hong, David S.; Heist, Rebecca S.; Awad, Mark M.; Skoulidis, Ferdinandos
Molecular determinants of KRAS p.G12C inhibitor efficacy in advanced NSCLC
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Negrao, Marcelo V.; Araujo, Haniel A.; Lamberti, Giuseppe; Cooper, Alissa J.; Zhou, Teng; Akhave, Neal; Delasos, Lukas; Hicks, J. Kevin; Aldea, Mihaela; Minuti, Gabriele; Hines, Jacobi; Aredo, Jacqueline V.; Dennis, Michael J.; Chakrabarti, Turja; Scott, Susan; Bironzo, Paolo; Scheffler, Matthias; Christopoulos, Petros; Kim, So Yeon; Goldberg, Sarah; Ni, Ying; Resuli, Blerina; Landi, Lorenza; Tseng, Shu-Chi; Nishino, Mizuki; Owen, Dwight; Blakely, Collin; Mountzios, Giannis; Shu, Catherine A.; Bestvina, Christine; Garassino, Marina; Marrone, Kristen; Gray, Jhanelle; Patel, Sandip Pravin; Cummings, Amy L.; Wakelee, Heather A.; Wolf, Jurgen; Scagliotti, Giorgio V.; Cappuzzo, Federico; Barlesi, Fabrice; Patil, Pradnya; Gibbons, Don L.; Meric-Bernstam, Funda; Lee, J. Jack; Heymach, John V.; Hong, David S.; Heist, Rebecca S.; Awad, Mark M.; Skoulidis, Ferdinandos
Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study

奥希替尼治疗非典型EGFR激活突变的非小细胞肺癌: 一项回顾性多中心研究

JTO CLINICAL AND RESEARCH REPORTS
IF3.5
2023-03-0120
OA
Ji, Jingran; Aredo, Jacqueline, V; Piper-Vallillo, Andrew; Huppert, Laura; Rotow, Julia K.; Husain, Hatim; Stewart, Susan; Cobb, Rosemary; Wakelee, Heather A.; Blakely, Collin M.; Wong, Melisa L.; Gubens, Matthew A.; Madani, Mohammad H.; Digumarthy, Subba R.; Mccoach, Caroline; Piotrowska, Zofia; Neal, Joel W.; Riess, Jonathan W.
AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer
CANCER DISCOVERY
IF33.3
2022-07-2757
OAAI
Noronha, Ashish; Nataraj, Nishanth Belugali; Lee, Joo Sang; Zhitomirsky, Benny; Oren, Yaara; Oster, Sara; Lindzen, Moshit; Mukherjee, Saptaparna; Will, Rainer; Ghosh, Soma; Simoni-Nieves, Arturo; Verma, Aakanksha; Chatterjee, Rishita; Borgoni, Simone; Robinson, Welles; Sinha, Sanju; Brandis, Alexander; Kerr, D. Lucas; Wu, Wei; Sekar, Arunachalam; Giri, Suvendu; Chung, Youngmin; Drago-Garcia, Diana; Danysh, Brian P.; Lauriola, Mattia; Fiorentino, Michelangelo; Ardizzoni, Andrea; Oren, Moshe; Blakely, Collin M.; Ezike, Jideofor; Wiemann, Stefan; Parida, Laxmi; Bivona, Trever G.; Aqeilan, Rami, I; Brugge, Joan S.; Regev, Aviv; Getz, Gad; Ruppin, Eytan; Yarden, Yosef
Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2022-07-0133
OAAI
Nanjo, Shigeki; Wu, Wei; Karachaliou, Niki; Blakely, Collin M.; Suzuki, Junji; Chou, Yu-Ting; Ali, Siraj M.; Kerr, D. Lucas; Olivas, Victor R.; Shue, Jonathan; Rotow, Julia; Mayekar, Manasi K.; Haderk, Franziska; Chatterjee, Nilanjana; Urisman, Anatoly; Yeo, Jia Chi; Skanderup, Anders J.; Tan, Aaron C.; Tam, Wai Leong; Arrieta, Oscar; Hosomichi, Kazuyoshi; Nishiyama, Akihiro; Yano, Seiji; Kirichok, Yuriy; Tan, Daniel S. W.; Rosell, Rafael; Okimoto, Ross A.; Bivona, Trever G.

研究方向

暂未获取到该数据
T
Trever G. Bivona
H 指数:67论文数:358被引数:2.1万
V
Victor Olivas
H 指数:23论文数:118被引数:4,995
J
Julia Rotow
H 指数:23论文数:216被引数:3,922
C
Caroline E. McCoach
H 指数:30论文数:167被引数:5,583
W
Wei Wu
H 指数:44论文数:254被引数:7,020
R
Robert C. Doebele
H 指数:74论文数:534被引数:3.1万
J
Jonathan W. Riess
H 指数:43论文数:537被引数:1.4万
D
D. Lucas Kerr
H 指数:14论文数:45被引数:1,446
M
Matthew A. Gubens
H 指数:44论文数:180被引数:2.1万
D
David M. Jablons
H 指数:70论文数:567被引数:2.0万