Patrick Schöffski - Publications, H-index & Citations

Patrick Schöffski

university hospitals leuven

93H指数

1.1K论文数

4.4W被引数

收录论文 243

发表时间

GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors GPNMB导向的CAR T细胞疗法对抗MiT/TFE家族融合驱动型实体瘤

Nature Cancer

IF28.5

2026-07-01

PREAI

Franz J. Zemp; Zackariah Breckenridge; Hyojin Song; Gurveer S. Gill; Taye L. Louie; Kiran Narta; Hongrui Liu; Yeon Suh; Louisa Guignard; Edna Ayerim Mandujano-Tinoco; Nicolás Collao; Joanna Pyczek; Kristofor K. Ellestad; Jada Curry; Jethro Langley; Cini John; Laura K. Mah; Jahanara Rajwani; Danyel Evseev; Madison Turk; Sacha Benaoudia; Jonathan Alex; Victor Naumenko; Varsha Thoppey Manoharan; Mobina Kazemi Mehrabadi; Harmony A. Smith; Geneece N. Y. Gilbert; Aaron Gillmor; Ted B. Verhey; Hayley M. Todesco; Katalin Osz; Bo-Young Ahn; Ana Bogossian; Colleen Anderson; Saif Sikdar; Shahrbano Rukunuddin; Tarek A. Bismar; Daniel Y. C. Heng; Keith Lawson; W. Marston Linehan; Haley Pedersen; Paul M. K. Gordon; John B. McIntyre; John MacGregor; Livia Garzia; Kathy Brodeur-Robb; Lisa DiFrancesco; Travis Ogilvie; Patrick Schöffski; Agnieszka Wozniak; Robert A. Holt; John Bell; Donna L. Senger; Victor Lewis; Michael Monument; Omar Khan; Lou Baudrier; Pierre Billon; Vincent Gabriel; Jeff Biernaskie; Kyle Potts; Kiril Trpkov; Kevin Hay; Jennifer Quizi; Jennifer Chan; Ramy Saleh; Jan Willem Henning; Nicole L. Prokopishyn; Mona Shafey; A. Sorana Morrissy; Douglas J. Mahoney

Phase I/Ib study evaluating safety, efficacy, pharmacokinetics and pharmacodynamics of NIZ985 monotherapy and in combination with an anti-PD-1 agent in patients with advanced solid tumors or lymphoma I期/ Ib期研究评估NIZ985单药治疗及联合抗PD-1药物在晚期实体瘤或淋巴瘤患者中的安全性、有效性、药代动力学和药效动力学

European Journal of Cancer

IF7.1

2026-06-24

PREAI

Elena Garralda; Patrick Schöffski; Arjun Oberoi; Martin Schuler; Heike Richly; Paolo A. Ascierto; Chia-Chi Lin; Rosa Álvarez; Sandip Pravin Patel; Yan Xing; Vivek Subbiah; Nancy Lewis; Shonika Patel; Lydia Wang-L-akshman; Jong Bong Lee; Nadia B. Hassounah; Lang Ho Lee; Mike Roy; Souvik Banerjee; Aimee Reynolds

Tazemetostat, an EZH2 inhibitor, in solid tumors harboring SWI/SNF alterations: a phase II basket study Tazemetostat，一种EZH2抑制剂，在携带SWI/SNF突变的实体瘤中的II期篮式研究

Nature Communications

IF15.7

2026-03-25

OAAI

Mrinal Gounder; Patrick Schöffski; Robin L. Jones; Silvia Stacchiotti; George D. Demetri; Gregory M. Cote; Mark Agulnik; Rashmi Chugh; Thierry Jahan; Abha A. Gupta; Tom Wei-Wu Chen; Ravin Ratan; Palma Dileo; Alexander Drilon; Gabriel G. Malouf; Attila Szanto; Neal Gupta; Nizar M. Tannir

Molecular epidemiology of the expression of urokinase plasminogen activator receptor-associated protein (uPARAP) in mesenchymal malignancies 间质恶性肿瘤中尿激酶型纤溶酶原激活物受体相关蛋白（uPARAP）表达分子流行病学

Translational Oncology

IF4.1

2026-02-23

OAAI

Chao-Chi Wang; Pernille Barkholt; Agnieszka Wozniak; Ulla Vanleeuw; Che-Jui Lee; Luna De Sutter; Lore De Cock; Kimberly Verbeeck; Lars Henning Engelholm; Carmel Lynch; Dominik Mumberg; Patrick Schöffski

Phase I/II Study of AXL-Specific Antibody-Drug Conjugate Enapotamab Vedotin in Patients with Advanced Solid Tumors 晚期实体瘤患者AXL特异性抗体药物偶联物Enapotamab Vedotin的I/II期研究

Cancer Research Communications

IF0

2025-11-01

OAAI

Rohrberg, Kristoffer Staal; Lopez, Juanita S.; Milhem, Mohammed M.; Blank, Christian U.; Reijers, Irene; Thistlethwaite, Fiona; Plummer, Ruth; Piha-Paul, Sarina A.; Janne, Pasi A.; Shum, Elaine; Shaw, Heather M.; Debruyne, Philip R.; Lao, Cristopher; Baurain, Jean-Francois; Choe, Jennifer H.; Gort, Eelke; Zhao, Yujie; Jerusalem, Guy; Schoffski, Patrick; Chen, Andrew William; Cohen, Eric A.; Mankowski, Walter C.; Roshkovan, Leonid; Katz, Sharyn I.; Kontos, Despina; Brady, Lauren K.; Qutaish, Mohammed; Castro, Patricia Garrido; Pencheva, Nora; Bajaj, Gaurav; Fu, Yali; Windfeld, Kristian; Reiter, Panagiota; Jure-Kunkel, Maria; Higgs, Brandon W.; Amiri, Katayoun I.; Ahmadi, Tahamtan; Forssmann, Ulf; Ramalingam, Suresh S.; Vergote, Ignace

BOS172738, a selective RET inhibitor, for the treatment of patients with RET-altered tumors including RET-fusion-positive non-small-cell lung cancer and RET-mutant medullary thyroid cancer: a phase I dose-escalation/expansion multicenter study BOS172738，一种选择性RET抑制剂，用于治疗RET基因变异的肿瘤患者，包括RET融合阳性的非小细胞肺癌和RET突变型甲状腺髓样癌：一项多中心I期剂量递增/扩展研究

ESMO Open

IF8.3

2025-09-24

PREAI

P. Schöffski; A. Gazzah; J. Trigo; A. Italiano; P. Gougis; V. Subbiah; J.-Y. Shih; H.H. Loong; B. Doger; M. Keegan; B. Jeglinski; K. Andreas; B.C. Cho

Establishment of patient-derived 3D in vitro models of sarcomas: literature review and guidelines on behalf of the FORTRESS working group 建立来源于患者的肉瘤3D体外模型：文献综述和FORTRESS工作组指南

NEOPLASIA

IF7.7

2025-07-01

PREAI

De Cock, Lore; Palubeckaite, Ieva; Bersani, Francesca; Faehling, Tobias; Pasquali, Sandro; Umbaugh, Sam; Meister, Michael Torsten; Danks, Molly R.; Manasterski, Piotr; Miallot, Richard; Krumbholz, Manuela; Roohani, Siyer; Heymann, Dominique; Cidre-Aranaz, Florencia; Wozniak, Agnieszka; Schoffski, Patrick; Bovee, Judith V. M. G.; Merlini, Alessandra; Venneker, Sanne

Final results from the phase Ia/Ib study of the novel bromodomain and extra-terminal domain inhibitor, BI 894999, in patients with advanced solid tumors or diffuse large B-cell lymphoma 新型溴结构域和-extra-terminal结构域抑制剂BI 894999在晚期实体瘤或弥漫性大B细胞淋巴瘤患者中的Ia/Ib期研究最终结果

ESMO OPEN

IF8.3

2025-05-01

PREAI

Lauer, U. M.; Awada, A.; Postel-Vinay, S.; Shapiro, G. I.; Thieblemont, C.; Piha-Paul, S. A.; Paik, P. K.; Shepard, D. R.; Docampo, L. I.; Galot, R.; Rottey, S.; Sadrolhefazi, B.; Marzin, K.; Musa, H.; Schoffski, P.

Clinical course and prognostic factors of patients with dedifferentiated liposarcoma: a retrospective analysis

BMC CANCER

IF3.4

2025-03-21

OAAI

Casier, Jelena; Timmermans, Iris; Laenen, Annouschka; Hompes, Daphne; Douchy, Thomas; Sciot, Raf; Christiaens, Melissa; Wafa, Hazem; Schoeffski, Patrick

First-in-human, phase 1 dose escalation study of SL-279252, a hexameric PD1-Fc-OX40L fusion protein, in patients with advanced solid tumors and lymphoma

INVESTIGATIONAL NEW DRUGS

IF2.7

2025-03-01

PREAI

Johnson, Melissa; Hong, David; Brana, Irene; Schoffski, Patrick; Galvao, Vladimir; Rangwala, Fatima; Ma, Bo; Hernandez, Robert; Kamat, Asha; Kato, Kazunobu; Schreiber, Taylor H.; Pandite, Lini; Siu, Lillian L.

Patient-derived xenograft models of gastrointestinal stromal tumors provide a ready-to-use platform for translational research

DISEASE MODELS & MECHANISMS

IF3.3

2025-02-21

OAAI

De Sutter, Luna; De Cock, Lore; Wang, Chao-Chi; Gorgeles, Daniel; Wyns, Karo; Verbeeck, Kimberly; Vanleeuw, Ulla; Douchy, Thomas; Hompes, Daphne; Jaekers, Joris; Van Raemdonck, Dirk; Vanden Bempt, Isabelle; Debiec-Rychter, Maria; Sciot, Raf; Wozniak, Agnieszka; Schoffski, Patrick

Pharmacokinetic profile and in vivo anticancer efficacy of anagrelide administered subcutaneously in rodents 啮齿动物皮下注射阿那格雷的药代动力学特征和体内抗癌功效

DRUG DELIVERY

IF8.1

2025-02-10

OAAI

Toivanen, Kirsi; De Sutter, Luna; Wozniak, Agnieszka; Wyns, Karo; Merikoski, Nanna; Salmikangas, Sami; Duan, Jianmin; Maksimow, Mikael; Lahtinen, Maria; Bohling, Tom; Schoffski, Patrick; Sihto, Harri

Current unmet needs in locally advanced (unresectable) or metastatic dedifferentiated liposarcoma, the relevance of progression-free survival as clinical endpoint, and expectations for future clinical trial design: an international Delphi consensus report

ESMO OPEN

IF8.3

2024-07-01

OAAI

Schoffski, P.; Jones, R. L.; Agulnik, M.; Blay, J. Y.; Chalmers, A.; Italiano, A.; Pink, D.; Stacchiotti, S.; Valverde, C.; Vincenzi, B.; Wagner, M. J.; Maki, R.

Safety and efficacy of nintedanib as second-line therapy for patients with differentiated or medullary thyroid cancer progressing after first-line therapy. A randomized phase II study of the EORTC Endocrine Task Force (protocol 1209-EnTF)

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2024-06-27

OAAI

Leboulleux, Sophie; Kapiteijn, Ellen; Litiere, Saskia; Schoffski, Patrick; Godbert, Yann; Rodien, Patrice; Jarzab, Barbara; Salvatore, Domenico; Zanetta, Sylvie; Capdevila, Jaume; Bastholt, Lars; de la Fouchardiere, Christelle; Lalami, Yassine; Bardet, Stephane; Cornelis, Frank; Dedecjus, Marek; Links, Thera; Sents, Ward; Schlumberger, Martin; Locati, D. Laura; Newbold, Katie

Recurrent and novel fusions detected by targeted RNA sequencing as part of the diagnostic workflow of soft tissue and bone tumours

JOURNAL OF PATHOLOGY CLINICAL RESEARCH

IF3.7

2024-05-13

OAAI

Baltazar, Rafael Zago; Claerhout, Sofie; Vander Borght, Sara; Spans, Lien; Sciot, Raphael; Schoffski, Patrick; Hompes, Daphne; Sinnaeve, Friedl; Wafa, Hazem; Renard, Marleen; van den Hout, Mari F. C. M.; Vernemmen, Astrid; Libbrecht, Louis; De Roo, An-Katrien; Mazzeo, Filomena; van Marcke, Cedric; Deraedt, Karen; Bourgain, Claire; Vanden Bempt, Isabelle

Optical Genome Mapping for Comprehensive Cytogenetic Analysis of Soft-Tissue and Bone Tumors for Diagnostic Purposes

JOURNAL OF MOLECULAR DIAGNOSTICS

IF3.4

2024-05-01

OAAI

Baelen, Jef; Dewaele, Barbara; Debiec-Rychter, Maria; Sciot, Raphael; Schoffski, Patrick; Hompes, Daphne; Sinnaeve, Friedl; Wafa, Hazem; Vanden Bempt, Isabelle

Ecubectedin and PM54 demonstrate antitumor activity in patient-derived xenograft models of soft tissue sarcoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Gorgels, Daniel; Wozniak, Agnieszka; Wang, Chao-Chi; Aviles, Pablo M.; Guillen, Maria J.; Cuevas, Carmen; Schoffski, Patrick

PEC-PRO: A new prognostic score from a series of 87 patients with localized perivascular epithelioid cell neoplasms (PEComas) treated with curative intent

CANCER

IF5.1

2024-03-12

OAAI

Gantzer, Justine; Toulmonde, Maud; Severac, Francois; Chamseddine, Ali N.; Charon-Barra, Celine; Vinson, Charles; Hervieu, Alice; Bourgmayer, Agathe; Bertucci, Francois; Ryckewaert, Thomas; Valentin, Thibaud; Firmin, Nelly; Chaigneau, Loic; Bompas, Emmanuelle; Follana, Philippe; Rioux-Leclercq, Nathalie; Soibinet-Oudot, Pauline; Bozec, Laurence; Le Loarer, Francois; Weingertner, Noelle; Chevreau, Christine; Duffaud, Florence; Blay, Jean-Yves; Kurtz, Jean-Emmanuel; Schoffski, Patrick; Brahmi, Mehdi; Malouf, Gabriel G.

Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial 瑞替尼与舒尼替尼治疗胃肠道间质瘤: 3期临床试验的ctDNA生物标志物分析

NATURE MEDICINE

IF50

2024-01-05

OAAI

Heinrich, Michael C.; Jones, Robin L.; George, Suzanne; Gelderblom, Hans; Schoeffski, Patrick; von Mehren, Margaret; Zalcberg, John R.; Kang, Yoon-Koo; Razak, Albiruni Abdul; Trent, Jonathan; Attia, Steven; Le Cesne, Axel; Siontis, Brittany L.; Goldstein, David; Boye, Kjetil; Sanchez, Cesar; Steeghs, Neeltje; Rutkowski, Piotr; Druta, Mihaela; Serrano, Cesar; Somaiah, Neeta; Chi, Ping; Reichmann, William; Sprott, Kam; Achour, Haroun; Sherman, Matthew L.; Ruiz-Soto, Rodrigo; Blay, Jean-Yves; Bauer, Sebastian

A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignancies

ONCOIMMUNOLOGY

IF6.3

2023-12-20

OAAI

Lin, Chia-Chi; Garralda, Elena; Schoeffski, Patrick; Hong, David S.; Siu, Lillian L.; Martin, Miguel; Maur, Michela; Hui, Rina; Soo, Ross A.; Chiu, Joanne; Zhang, Tian; Ma, Brigette; Kyi, Chrisann; Tan, Daniel S. W.; Cassier, Philippe A.; Sarantopoulos, John; Weickhardt, Andrew; Carvajal, Richard D.; Spratlin, Jennifer; Esaki, Taito; Rolland, Frederic; Akerley, Wallace; Deschler-Baier, Barbara; Rispoli, Lawrence; Samant, Tanay S.; Chowdhury, Niladri Roy; Gusenleitner, Daniel; Kwak, Eunice L.; Askoxylakis, Vasileios; De Braud, Filippo

研究方向