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Palmer Taylor

sapienza university rome

86H指数
576论文数
2.6W被引数
收录论文 137
发表时间
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The Ionizing Zwitterionic Oxime Antidote Attenuates Gliosis in Mice Exposed to Sarin离子化两性离子羟胺解毒剂减轻暴露于沙林的小鼠的胶质增生
errChemico-Biological Interactions
IF5.4
err2025-09-30
err0
PREAI
errNikolina Maček Hrvat; Borna Puljko; Rakesh K. Sit; Katarina Ilić; Dora Kolić; Kristina Mlinac-Jerkovic; Svjetlana Kalanj-Bognar; Zoran Radić; Barry K. Sharpless; Palmer Taylor; Zrinka Kovarik
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RS194B oxime mediated AChE-reactivation and protection in lethal sarin and insecticide organophosphate exposed macaques is accompanied by oxime-independent BChE increases; likely a result of liver damageRS194B羟肟酸介导的AChE再活化和保护作用在接触致死性沙林和杀虫剂有机磷的猕猴中，伴随着羟肟酸非依赖性的BChE增加；这可能是肝损伤的结果。
errChemico-Biological Interactions
IF5.4
err2025-05-24
err0
PREAI
errYvonne J. Rosenberg; Xiaoming Jiang; Lori A. Urban; Dennis Sullivan; Zoran Radic; Palmer Taylor; Zrinka Kovarik
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The Cyclic Imine Core Common to the Marine Macrocyclic Toxins Is Sufficient to Dictate Nicotinic Acetylcholine Receptor Antagonism
errMARINE DRUGS
IF5.4
err2024-03-27
err0
errOAAI
errBourne, Yves; Sulzenbacher, Gerlind; Chabaud, Laurent; Araoz, Romulo; Radic, Zoran; Conrod, Sandrine; Taylor, Palmer; Guillou, Catherine; Molgo, Jordi; Marchot, Pascale
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Differential Activation and Desensitization States Promoted by Noncanonical α7 Nicotinic Acetylcholine Receptor Agonists
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2022-11-01
err1
errOAAI
errStokes, Clare; Camacho-Hernandez, Gisela Andrea; Thakur, Ganesh A.; Wu, Xiaoxuan; Taylor, Palmer; Papke, Roger L.
err分享
err收藏
Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins
errMARINE DRUGS
IF5.4
err2022-01-04
err5
errOAAI
errKem, William R.; Andrud, Kristin; Bruno, Galen; Xing, Hong; Soti, Ferenc; Talley, Todd T.; Taylor, Palmer
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Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects有机磷酸酯对hAChE的共价抑制通过长距离变构作用导致同型二聚体解离
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2021-09-01
err8
errOAAI
errBlumenthal, Donald K.; Cheng, Xiaolin; Fajer, Mikolai; Ho, Kwok-Yiu; Rohrer, Jacqueline; Gerlits, Oksana; Taylor, Palmer; Juneja, Puneet; Kovalevsky, Andrey; Radic, Zoran
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Cholinergic Capsules and Academic Admonitions
errANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 61, 2021
IF0
err2021-01-06
err2
errOAAI
errTaylor, Palmer
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Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[18F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [18F]-VXS
errANNALS OF THE NEW YORK ACADEMY OF SCIENCES
IF4.8
err2020-05-20
err2
errOAAI
errHayes, Thomas R.; Blecha, Joseph E.; Chao, Chih-Kai; Huynh, Tony L.; VanBrocklin, Henry D.; Zinn, Kurt R.; Taylor, Palmer W.; Gerdes, John M.; Thompson, Charles M.
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Rational design, synthesis, and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase (vol 295, pg 4079, 2020)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-05-01
err1
errOAAI
errGorecki, Lukas; Gerlits, Oksana; Kong, Xiaotian; Cheng, Xiaolin; Blumenthal, Donald K.; Taylor, Palmer; Ballatore, Carlo; Kovalevsky, Andrey; Radic, Zoran
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Rational design, synthesis and evaluation of smart, uncharged bis-oxime antidotes of OP inhibited human acetylcholinesterase
errFASEB JOURNAL
IF4.2
err2020-04-19
err0
PREAI
errRadic, Zoran; Gorecki, Lukas; Gerlits, Oksana; Kong, Xiaotian; Cheng, Xiaolin; Blumenthal, Donald; Taylor, Palmer; Ballatore, Carlo; Kovalevsky, Andrey
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Pharmacokinetic Analysis of Ionizable Zwitterionic Oximes: Antidotes to Organophosphate Exposure
errFASEB JOURNAL
IF4.2
err2020-04-18
err0
errOAAI
errSamskey, Nathan; Ho, Kwok-Yiu; Momper, Jeremiah; Radic, Zoran; Sit, Rakesh; Sharpless, K.; Taylor, Palmer
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Targeting the Homomeric α7 Nicotinic Receptor and Acetylcholine Binding Protein with Lophotoxin by X-ray Crystallography and Mass Spectrometry
errFASEB JOURNAL
IF4.2
err2020-04-18
err1
errOAAI
errHernandez, Gisela; Schnarkowski, Franziska; Harel, Michal; Ho, Kwok-Yiu; Campeau, Anaamika; Sankaran, Banumathi; Gonzalez, David; Fenical, William; Taylor, Palmer
err分享
err收藏
Rational design, synthesis, and evaluation of uncharged, ?smart? bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-03-01
err30
errOAAI
errGorecki, Lukas; Gerlits, Oksana; Kong, Xiaotian; Cheng, Xiaolin; Blumenthal, Donald K.; Taylor, Palmer; Ballatore, Carlo; Kovalevsky, Andrey; Radic, Zoran
err分享
err收藏
Synthesis, Pharmacological Characterization, and Structure-Activity Relationships of Noncanonical Selective Agonists for α7 nAChRs
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2019-11-01
err18
errOAAI
errCamacho-Hernandez, Gisela Andrea; Stokes, Clare; Duggan, Brendan M.; Kaczanowska, Katarzyna; Brandao-Araiza, Stefania; Doan, Lisa; Papke, Roger L.; Taylor, Palmer
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Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase在天然和VX抑制的人乙酰胆碱酯酶的室温x射线结构中揭示了结合的肟再激活剂的生产性重新取向
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2019-07-01
err13
errOAAI
errGerlits, Oksana; Kong, Xiaotian; Cheng, Xiaolin; Wymore, Troy; Blumenthal, Donald K.; Taylor, Palmer; Radic, Zoran; Kovalevsky, Andrey
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Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase通过与乙酰胆碱酯酶的活性中心峡谷突变体相互作用的吡啶鎓醛肟的再活化来抵消塔本抑制
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2019-06-01
err10
PREAI
errKovarik, Zrinka; Hrvat, Nikolina Macek; Kalisiak, Jaroslaw; Katalinic, Maja; Sit, Rakesh K.; Zorbaz, Tamara; Radic, Zoran; Fokin, Valery V.; Sharpless, K. Barry; Taylor, Palmer
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Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2018-11-01
err35
errOAAI
errSit, Rakesh K.; Kovarik, Zrinka; Hrvat, Nikolina Macek; Zunec, Suzana; Green, Carol; Fokin, Valery V.; Sharpless, K. Barry; Radic, Zoran; Taylor, Palmer
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Planarian cholinesterase: molecular and functional characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity
errARCHIVES OF TOXICOLOGY
IF6.9
err2017-11-22
err34
errOAAI
errHagstrom, Danielle; Zhang, Siqi; Ho, Alicia; Tsai, Eileen S.; Radic, Zoran; Jahromi, Aryo; Kaj, Kelson J.; He, Yingtian; Taylor, Palmer; Collins, Eva-Maria S.
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Substituted 2-Aminopyrimidines Selective for α7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2017-03-01
err19
PREAI
errKaczanowska, Katarzyna; Camacho Hernandez, Gisela Andrea; Bendiks, Larissa; Kohs, Larissa; Manuel Comejo-Bravo, Jose; Harel, Michal; Finn, M. G.; Taylor, Palmer
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Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation
errARCHIVES OF TOXICOLOGY
IF6.9
err2016-12-18
err31
errOAAI
errHagstrom, Danielle; Hirokawa, Hideto; Zhang, Limin; Radic, Zoran; Taylor, Palmer; Collins, Eva-Maria S.
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研究方向

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合作学者
合作期刊
N
Nicholas G. Martin
H 指数: 221 · 论文数: 2.8K
T
Thomas C. Südhof
H 指数: 192 · 论文数: 751
G
Grant W. Montgomery
H 指数: 188 · 论文数: 1.2K
J
John R. Yates
H 指数: 188 · 论文数: 1.5K
R
Roger Y. Tsien
H 指数: 164 · 论文数: 582
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