Donald J. Buchsbaum - Publications, H-index & Citations

Donald J. Buchsbaum

cerflux, inc.

55H指数

472论文数

1.2W被引数

收录论文 140

发表时间

Pan-RAS Inhibitors: Expanding Therapeutic Potential and Evading Resistance 泛-RAS抑制剂：拓展治疗潜力与规避耐药性

Cancers

IF4.4

2026-06-04

OAAI

Sindhu Ramesh; Junwei Wang; Chung-Hui Huang; Austin M. Moore; Khalda Fadlalla; Kristy L. Berry; Yulia Y. Maxuitenko; Xi Chen; Adam B. Keeton; Bassel El-Rayes; Donald J. Buchsbaum; Karim I. Budhwani; Gang Zhou; Amit K. Mitra; Gary A. Piazza

Evaluation of a Novel Pan-RAS Inhibitor in 3D Bioprinted Tumor Models 评估一种新型泛RAS抑制剂的3D生物打印肿瘤模型

Cancers 2025, Vol. 17, Page 2958

IF0

2025-09-10

OAAI

Daniela D. De Nobrega; Logan C. Eiler; Parmanand Ahirwar; Sonika Nallapu; Urvi P. Rawal; Chelsea L. Crawford; Donald J. Buchsbaum; Adam B. Keeton; Yulia Y. Maxuitenko; Xi Chen; Gary A. Piazza; Allan Tsung; Karim I. Budhwani

ADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma ADT-1004: 在胰腺导管腺癌的临床前模型中具有强大抗肿瘤活性的一流口服pan-ras抑制剂

MOLECULAR CANCER

IF33.9

2025-03-13

OAAI

Bandi, Dhana Sekhar Reddy; Nagaraju, Ganji Purnachandra; Sarvesh, Sujith; Carstens, Julienne L.; Foote, Jeremy B.; Graff, Emily C.; Fang, Yu-Hua D.; Keeton, Adam B.; Chen, Xi; Valiyaveettil, Jacob; Berry, Kristy L.; Bae, Sejong; Akce, Mehmet; Gorman, Greg; Yoon, Karina J.; Manne, Upender; Boyd, Michael R.; Buchsbaum, Donald J.; Azmi, Asfar S.; Maxuitenko, Yulia Y.; Piazza, Gary A.

A novel pan-RAS inhibitor (ADT-1004) with superior efficacy over mutation-specific KRAS inhibitors in mouse models of pancreatic cancer

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Bandi, D. S. R.; Nagaraju, G. P.; Foote, J. B.; Keeton, A.; Chen, X.; Berry, K. L.; Maxuitenko, Y. Y.; Manne, U.; Buchsbaum, D. J.; Piazza, G. A.; El-Rayes, B. F.

Survival benefit and tumor regression with a dual RAS/β-catenin inhibitor, ADT-030, in murine models of pancreatic and lung cancer

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Bandi, D. S. R.; Nagaraju, G. P.; Foote, J. B.; Keeton, A.; Chen, X.; Berry, K. L.; Maxuitenko, Y. Y.; Manne, U.; Buchsbaum, D. J.; Piazza, G. A.; El-Rayes, B. F.

A novel pan-RAS/ β-catenin inhibitor, ADT-030, produces tumor regression in PDX models of pancreatic cancer

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Bandi, Dhana Sekhar Reddy; Nagaraju, Ganji P.; Foote, Jeremy B.; Keeton, Adam B.; Chen, Xi; Berry, Kristy L.; Maxuitenko, Yulia Y.; Manne, Upender; Buchsbaum, Donald J.; Piazza, Gary A.; El-Rayes, Bassel F.

Efficacy advantages of a novel pan-RAS inhibitor, ADT-1004, over mutant- specific KRAS inhibitors for suppressing pancreatic tumor growth in murine models

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

BET inhibition decreases HMGCS2 and sensitizes resistant pancreatic tumors to gemcitabine

CANCER LETTERS

IF10.1

2024-06-01

PREAI

Miller, Aubrey L.; Fehling, Samuel C.; Vance, Rebecca B.; Chen, Dongquan; Brown, Eric Josh; Hossain, M. Iqbal; Heard, Eric O.; Andrabi, Shaida A.; Wang, Hengbin; Yang, Eddy S.; Buchsbaum, Donald J.; van Waardenburg, Robert C. A. M.; Bellis, Susan L.; Yoon, Karina J.

ADT-1004: A promising pan-RAS inhibitor for targeting KRAS mutations in pancreatic ductal adenocarcinoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Bandi, Dhana Sekhar Reddy; Ganji, Purnachandra Nagaraju; Sarvesh, Sujith; Maxuitenko, Yulia; Foote, Jeremy B.; Keeton, Adam B.; Chen, Xi; Buchsbaum, Donald; Piazza, Gary; El-Rayes, Bassel

Novel Pan-RAS inhibitor ADT-007: A unique mechanism of antitumor selectivity in pancreatic and colorectal carcinoma models

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Wang, Junwei; Keeton, Adam B.; Ramesh, Sindhu; Johnson, Peyton; Maxuitenko, Yulia Y.; Foote, Jeremy B.; Huang, Chung-Hui; Berry, Kristy L.; Fadlalla, Khalda; Reddy, Bandi D.; Nagaraju, Ganji P.; Nurmemmedov, Elmar; Babic, Ivan; Gaponenko, Vadim; Chen, Xi; El-Rayes, Bassel F.; Buchsbaum, Donald J.; Piazza, Gary A.

Efficacy and tolerability of a novel pan-RAS inhibitor with a unique mechanism of selectivity in mouse models of pancreatic cancer

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-01

PREAI

Keeton, Adam B.; Maxuitenko, Yulia Y.; Foote, Jeremy B.; Huang, Chung -Hui; Berry, Kristy L.; Fadlalla, Khalda; Nagaraju, Ganji P.; Reddy, Bandi D. S.; Chen, Xi; El-Rayes, Bassel F.; Buchsbaum, Donald J.; Piazza, Gary A.

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

JCI INSIGHT

IF6.1

2023-10-09

OAAI

Bhalerao, Nikita; Chakraborty, Asmi; Marciel, Michael P.; Hwang, Jihye; Britain, Colleen M.; Silva, Austin D.; Eltoum, Isam E.; Jones, Robert B.; Alexander, Katie L.; Smythies, Lesley E.; Smith, Phillip D.; Crossman, David K.; Crowley, Michael R.; Shin, Boyoung; Harrington, Laurie E.; Yan, Zhaoqi; Bethea, Maigen M.; Hunter, Chad S.; Klug, Christopher A.; Buchsbaum, Donald J.; Bellis, Susan L.

Antitumor activity of 1st-in-class pan-RAS inhibitor ADT-1004 in mouse models of pancreatic ductal adenocarcinoma

CANCER RESEARCH

IF16.6

2023-04-14

PREAI

Maxuitenko, Yulia Y.; Foote, Jeremy B.; Keeton, Adam B.; Chen, Xi; Berry, Kristy; Fadlalla, Khalda; Valiyaveettil, Jacob; Huang, Chung-Hui; Moore, Austin M.; Graff, Emily C.; Nagaraju, Ganji P.; Carstens, Julienne L.; El-Rayes, Bassel F.; Buchsbaum, Donald J.; Piazza, Gary A.

Oncogenic KRAS inhibition with ADT-007 primes T cell responses in pancreatic ductal adenocarcinoma

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Foote, Jeremy B.; Mattox, Tyler E.; Keeton, Adam B.; Purnachandra, Ganji N.; Maxuitenko, Yulia; Chen, Xi; Valiyaveettil, Jacob; Buchsbaum, Donald J.; Piazza, Gary A.; El-Rayes, Bassel F.

ADT-007 binds RAS and inhibits RAS signaling

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Keeton, Adam B.; Chen, Xi; Valiyaveettil, Jacob; Huang, Chung-Hui; Mattox, Tyler E.; Fadlalla, Khalda; Foote, Jeremy B.; Buchsbaum, Donald J.; Berry, Kristy L.; Nurmemmedov, Elmar; Babic, Ivan; Gaponenko, Vadim; Gorman, Gregory; Coward, Lori; Maxuitenko, Yulia Y.; Smith, Forrest T.; Piazza, Gary A.

Editorial: Targeting the Wnt/β-catenin signaling pathway in cancer

FRONTIERS IN ONCOLOGY

IF3.3

2022-09-13

OAAI

Patergnani, Simone; Buchsbaum, Donald J.; Piazza, Gary A.

Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Britain, Colleen M.; Bhalerao, Nikita; Silva, Austin D.; Chakraborty, Asmi; Buchsbaum, Donald J.; Crowley, Michael R.; Crossman, David K.; Edwards, Yvonne J. K.; Bellis, Susan L.

STAT3 and GR Cooperate to Drive Gene Expression and Growth of Basal-Like Triple-Negative Breast Cancer

CANCER RESEARCH

IF16.6

2020-10-15

OAAI

Conway, Megan E.; McDaniel, Joy M.; Graham, James M.; Guillen, Katrin P.; Oliver, Patsy G.; Parker, Stephanie L.; Yue, Peibin; Turkson, James; Buchsbaum, Donald J.; Welm, Bryan E.; Myers, Richard M.; Varley, Katherine E.

PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity

DRUG DISCOVERY TODAY

IF7.5

2020-08-01

OAAI

Piazza, Gary A.; Ward, Antonio; Chen, Xi; Maxuitenko, Yulia; Coley, Alex; Aboelella, Nada S.; Buchsbaum, Donald J.; Boyd, Michael R.; Keeton, Adam B.; Zhou, Gang

B7-H3-targeted Radioimmunotherapy of Human Cancer 人类癌症的B7-H3-targeted放射免疫治疗

CURRENT MEDICINAL CHEMISTRY

IF3.5

2020-07-07

OAAI

Kasten, Benjamin B.; Ferrone, Soldano; Zinn, Kurt R.; Buchsbaum, Donald J.

研究方向