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Decoding resistance to immune checkpoint inhibitors in non-small cell lung cancer: a comprehensive analysis of plasma proteomics and therapeutic implications 解读非小细胞肺癌对免疫检查点抑制剂的耐药性:血浆蛋白质组学及其治疗意义的综合分析 Harel, Michal; Dahan, Nili; Lahav, Coren; Jacob, Eyal; Elon, Yehonatan; Puzanov, Igor; Kelly, Ronan J.; Shaked, Yuval; Leibowitz, Raya; Carbone, David P.; Gandara, David R.; Dicker, Adam P. 分享 收藏
Racial Differences in Systemic Immune Parameters in Individuals With Lung Cancer von Itzstein, Mitchell S.; Liu, Jialiang; Mu-Mosley, Hong; Fattah, Farjana; Park, Jason Y.; Sorelle, Jeffrey A.; Farrar, J. David; Gwin, Mary E.; Hsiehchen, David; Gloria-McCutchen, Yvonne; Wakeland, Edward K.; Cole, Suzanne; Bhalla, Sheena; Kainthla, Radhika; Puzanov, Igor; Switzer, Benjamin; Daniels, Gregory A.; Zakharia, Yousef; Shaheen, Montaser; Zhang, Jianjun; Xie, Yang; Gerber, David E. 分享 收藏
Acquired resistance to PD-L1 inhibition enhances a type I IFN-regulated secretory program in tumors Shi, Yuhao; Mckenery, Amber; Dolan, Melissa; Mastri, Michalis; Hill, James W.; Dommer, Adam; Benzekry, Sebastien; Long, Mark; Abrams, Scott, I; Puzanov, Igor; Ebos, John M. L. 分享 收藏
Differential Infiltration of Key Immune T-Cell Populations Across Malignancies Varying by Immunogenic Potential and the Likelihood of Response to Immunotherapy 关键免疫T细胞群在恶性肿瘤中的差异浸润,其免疫原性潜力和对免疫疗法的反应可能性各不相同 Eljilany, Islam; Coleman, Sam; Tan, Aik Choon; Mccarter, Martin D.; Carpten, John; Colman, Howard; Naqash, Abdul Rafeh; Puzanov, Igor; Arnold, Susanne M.; Churchman, Michelle L.; Spakowicz, Daniel; Salhia, Bodour; Marin, Julian; Ganesan, Shridar; Ratan, Aakrosh; Shriver, Craig; Hwu, Patrick; Dalton, William S.; Weiner, George J.; Conejo-Garcia, Jose R.; Rodriguez, Paulo; Tarhini, Ahmad A. 分享 收藏
A phase I, first-in-human, dose escalation and expansion study of oral pan-RAF/MEK molecular glue NST-628 in subjects with solid tumors harboring RAS-MAPK pathway alterations 一项I期、首次人体、剂量递增和扩展研究,评估口服泛RAF/MEK分子胶NST-628在携带RAS-MAPK通路异常的实体瘤受试者中的效果。 Lemech, C.; Luke, J. J.; Falchook, G. S.; Mckean, M.; Kichenadasse, G.; Teng, C.; Vandross, A. L.; Salkeni, M. A.; Atkinson, V. G.; Liu, J. J.; Kennedy, A. M.; Clark, J.; Ryan, M.; Schmidt-Kittler, O.; Steinhubel, D.; Wages, D.; Komarnitsky, P.; Puzanov, I. 分享 收藏
Adjuvant Everolimus in Patients with Completely Resected, Very High-risk Renal Cell Carcinoma of Clear Cell Histology: Results from the Phase 3 Placebo-controlled SWOG S0931 (EVEREST) Trial Lara, Primo N., Jr.; Tangen, Catherine; Heath, Elisabeth I.; Gulati, Shuchi; Stein, Mark N.; Meng, Maxwell; Alva, Ajjai Shivaram; Pal, Sumanta K.; Puzanov, Igor; Clark, Joseph I.; Choueiri, Toni K.; Agarwal, Neeraj; Uzzo, Robert; Haas, Naomi B.; Synold, Timothy W.; Plets, Melissa; Vaishampayan, Ulka N.; Shuch, Brian M.; Lerner, Seth; Thompson, Ian M., Jr.; Ryan, Christopher W. 分享 收藏
First-in-human phase I trial of oncolytic herpes simplex virus ONCR-177 alone or in combination with pembrolizumab in advanced solid tumors 首次人体I期试验:评估溶瘤单纯疱疹病毒ONCR-177单药或联合帕博利珠单抗治疗晚期实体瘤的效果 Gaspar, C. Fava; Park, J. C.; Falchook, G. S.; Wesolowski, R.; Soliman, H.; Ott, P. A.; Bilen, M. A.; Mckean, M.; Villaflor, V.; Chow, L. Q. M.; Yanez, A.; Dupont, C.; Shepherd, J.; Cheema, T.; Goldberg, J. M.; Puzanov, I.; Spreafico, A. 分享 收藏
Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells Kirk, Jason S.; Wang, Jie; Long, Mark; Rosario, Spencer; Tracz, Amanda; Ji, Yibing; Kumar, Rahul; Liu, Xiaozhuo; Jamroze, Anmbreen; Singh, Prashant K.; Puzanov, Igor; Chatta, Gurkamal; Cheng, Qing; Huang, Jiaoti; Wrana, Jeffrey L.; Lovell, Jonathan; Yu, Han; Liu, Song; Shen, Michael M.; Liu, Tao; Tang, Dean G. 分享 收藏
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Use of artificial intelligence chatbots in clinical management of immune-related adverse events Burnette, Hannah; Pabani, Aliyah; von Itzstein, Mitchell S.; Switzer, Benjamin; Fan, Run; Ye, Fei; Puzanov, Igor; Naidoo, Jarushka; Ascierto, Paolo A.; Gerber, David E.; Ernstoff, Marc S.; Johnson, Douglas B. 分享 收藏
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Analysis of clonal heterogeneity within paired primary and metastatic tumor samples of patients with solid tumors and implications for neoantigen-based personalized cancer vaccines Obermayer, Alyssa; Shaw, Timothy; Chang, Darwin; Davis, Joshua; Teer, Jamie K.; Yu, Xiaoqing; Wang, Xuefeng; Hedges, Dale; Tan, Aik Choon; Rounbehler, Robert; Naqash, Abdul Rafeh; Gatti-Mays, Margaret; Ratan, Aakrosh; McCarter, Martin; Colman, Howard; Puzanov, Igor; Arnold, Susanne; Churchman, Michelle; Hwu, Patrick; Dalton, William; Weiner, George; Conejo-Garcia, Jose; Rodriguez, Paulo C.; Salhia, Bodour; Tarhini, Ahmad A. 分享 收藏
Plasma proteomics-based models for predicting therapeutic benefit and immunerelated adverse events in non-small cell lung cancer patients treated with immunotherapy Harel, Michal; Christopoulos, Petros; Puzanov, Igor; Bar, Jair; Kamer, Iris; Reinmuth, Niels; Koch, Ina; Moskovitz, Mor; Levy-Barda, Adva; Zer, Alona; Lotem, Michal; Farrugia, David; Katzenelson, Rivka; Price, Gillian; Agbarya, Abed; Cheley, Helen; Hassani, Adam; Abu-Amna, Mahmoud; Geldart, Tom; Chatterjee, Anirban; Polychronis, Andreas; Gottfried, Maya; Lou, Yanyan; Harkovsky, Tatiana; Brewster, Alison; Wolf, Ido; Tepper, Ella; Yellin, Ben; Sela, Itamar; Lahav, Coren; Elon, Yehonatan; Leibowitz, Raya; Dicker, Adam P.; Chae, Young Kwang; Sullivan, Ryan J.; Carbone, David; Gandara, David; Naidoo, Jarushka 分享 收藏
Differential infiltration of key immune cell populations across malignancies varying by immunogenic potential and likelihood of response to immunotherapy Tarhini, Ahmad A.; Eljilany, Islam; Coleman, Sam; Hedges, Dale J.; McCarter, Martin; Carpten, John; Colman, Howard; Naqash, Abdul Rafeh; Puzanov, Igor; Arnold, Susanne; Churchman, Michelle; Hwu, Patrick; Dalton, William S.; Weiner, George J.; Tan, Aik Choon; Conejo-Garcia, Jose R.; Rodriguez, Paulo C. 分享 收藏
Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy 肿瘤浸润淋巴细胞治疗的管理和最佳实践专家共识指南 Warner, Allison Betof; Hamid, Omid; Komanduri, Krishna; Amaria, Rodabe; Butler, Marcus O.; Haanen, John; Nikiforow, Sarah; Puzanov, Igor; Sarnaik, Amod; Bishop, Michael R.; Schoenfeld, Adam J. 分享 收藏
The impact of cancer metastases on COVID-19 outcomes: A COVID-19 and Cancer Consortium registry-based retrospective cohort study 癌症转移对新型冠状病毒肺炎结局的影响: 基于新型冠状病毒肺炎和癌症协会注册的回顾性队列研究 Castellano, Cecilia A.; Sun, Tianyi; Ravindranathan, Deepak; Hwang, Clara; Balanchivadze, Nino; Singh, Sunny R. K.; Griffiths, Elizabeth A.; Puzanov, Igor; Ruiz-Garcia, Erika; Vilar-Compte, Diana; Cardenas-Delgado, Ana I.; McKay, Rana R.; Nonato, Taylor K.; Ajmera, Archana; Yu, Peter P.; Nadkarni, Rajani; O'Connor, Timothy E.; Berg, Stephanie; Ma, Kim; Farmakiotis, Dimitrios; Vieira, Kendra; Arvanitis, Panos; Saliby, Renee M.; Labaki, Chris; El Zarif, Talal; Wise-Draper, Trisha M.; Zamulko, Olga; Li, Ningjing; Bodin, Brianne E.; Accordino, Melissa K.; Ingham, Matthew; Joshi, Monika; Polimera, Hyma V.; Fecher, Leslie A.; Friese, Christopher R.; Yoon, James J.; Mavromatis, Blanche H.; Brown, Jacqueline T.; Russell, Karen; Nanchal, Rahul; Singh, Harpreet; Tachiki, Lisa; Moria, Feras A.; Nagaraj, Gayathri; Cortez, Kimberly; Abbasi, Saqib H.; Wulff-Burchfield, Elizabeth M.; Puc, Matthew; Weissmann, Lisa B.; Bhatt, Padmanabh S.; Mariano, Melissa G.; Mishra, Sanjay; Halabi, Susan; Beeghly, Alicia; Warner, Jeremy L.; French, Benjamin; Bilen, Mehmet A. 分享 收藏
Merkel Cell Carcinoma, Version 1.2024 Featured Updates to the NCCN Guidelines Schmults, Chrysalyne D.; Blitzblau, Rachel; Aasi, Sumaira Z.; Alam, Murad; Amini, Arya; Bibee, Kristin; Bolotin, Diana; Bordeaux, Jeremy; Chen, Pei -Ling; Contreras, Carlo M.; Dimaio, Dominick; Donigan, Jessica M.; Farma, Jeffrey M.; Ghosh, Karthik; Harms, Kelly; Ho, Alan L.; Lukens, John Nicholas; Manber, Susan; Mark, Lawrence; Medina, Theresa; Nehal, Kishwer S.; Nghiem, Paul; Olino, Kelly; Park, Soo; Patel, Tejesh; Puzanov, Igor; Rich, Jason; Sekulic, Aleksandar; Shaha, Ashok R.; Srivastava, Divya; Thomas, Valencia; Tomblinson, Courtney; Venkat, Puja; Xu, Yaohui Gloria; Yu, Siegrid; Yusuf, Mehran; Mccullough, Beth; Espinosa, Sara 分享 收藏
Underrepresentation and underreporting of minoritized racial and ethnic groups in clinical trials on immune checkpoint inhibitors Chua, Alfredo V., Jr.; Delmerico, Jennifer; Sheng, Haiyang; Gandhi, Shipra; Puzanov, Igor; Sakoda, Lori C.; Morrow, Gary R.; Ambrosone, Christine B.; Kamen, Charles; Yao, Song 分享 收藏