未登录

C

Connor M. Blair

university of glasgow

H指数:6

被引数:165

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Discovery of a PDE4B and PDE4D selective bifunctional degrader for management of chronic inflammatory disorders

PDE4B和PDE4D选择性双功能降解剂在慢性炎症性疾病管理中的发现

Journal of Translational Autoimmunity

IF3.6

2025-10-310

OAAI

Precision peptide disruptors: The next generation of targeted therapeutics in oncology

CELLULAR SIGNALLING

IF3.7

2025-05-210

OA

SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2024-11-010

OAAI

Beta-amyloid interacts with and activates the long-form phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availability

IF3

2024-05-092

OA

Disruption of the pro-oncogenic c-RAF-PDE8A complex represents a differentiated approach to treating KRAS-c-RAF dependent PDAC

SCIENTIFIC REPORTS

IF3.9

2024-04-180

OAAI

Cancer: Phosphodiesterase type 4C (PDE4C), the forgotten subfamily as a therapeutic target

癌症: 4C型磷酸二酯酶 (PDE4C)，被遗忘的亚家族作为治疗靶点

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2023-09-014

OAAI

Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-06-1212

OAAI

Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2022-04-0115

OAAI

Reshaping cAMP nanodomains through targeted disruption of compartmentalised phosphodiesterase signalosomes

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2019-09-1022

OA

Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A-C-Raf

IF3.4

2019-03-2516

OAAI