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Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study 身体活动与结直肠癌分子亚型：一项合并的观察性分析和孟德尔随机化研究 Chalitsios, Christos, V; Markozannes, Georgios; Aglago, Elom K.; Berndt, Sonja, I; Buchanan, Daniel D.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Dimou, Niki; Drew, David A.; French, Amy J.; Georgeson, Peter; Giannakis, Marios; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Lynch, Brigid M.; Moreno, Victor; Murphy, Neil; Newton, Christina C.; Nowak, Jonathan A.; Obon-Santacana, Mireia; Ogino, Shuji; Qu, Conghui; Schmit, Stephanie L.; Steinfelder, Robert S.; Sun, Wei; Thomas, Claire E.; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Um, Caroline Y.; Van Guelpen, Bethany; Zaidi, Syed H.; Schoen, Robert E.; Woods, Michael O.; Brenner, Hermann; Andreson, Laura; Pellatt, Andrew J.; Peters, Ulrike; Phipps, Amanda, I; Tsilidis, Konstantinos K. 分享 收藏
The germline POLD1 c.1420 C > A (p.Leu474Ile) variant segregates with endometrial cancer, colorectal cancer and colonic polyps demonstrating hypermutation and defective POLD1 mutational signatures 生殖系POLD1 c.1420 C > A (p.Leu474Ile)变异与子宫内膜癌、结直肠癌和结肠息肉共存，表现出超突变和POLD1突变谱异常的特征。 Buchanan, Daniel D.; Georgeson, Peter; Walker, Romy; Joo, Jihoon E.; Clendenning, Mark; Como, Julia; O'keeffe, Ryan; Prisc, Alysha; Chu, Yen Lin; Jenkins, Mark A.; Rosty, Christophe; Winship, Ingrid M.; Macrae, Finlay A.; Ip, Emilia; Harris, Rebecca; Goodwin, Annabel; Mahmood, Khalid 分享 收藏
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Transcriptome-wide Mendelian randomization exploring dynamic CD4+T cell gene expression in colorectal cancer development 全转录组孟德尔随机化探讨结直肠癌发生中CD4+T细胞基因表达的动态变化 Deslandes, Benedita; Wu, Xueyan; Lee, Matthew A.; Goudswaard, Lucy J.; Jones, Gareth W.; Gsur, Andrea; Lindblom, Annika; Ogino, Shuji; Vymetalkova, Veronika; Wolk, Alicja; Wu, Anna H.; Huyghe, Jeroen R.; Peters, Ulrike; Phipps, Amanda, I; Thomas, Claire E.; Pai, Rish K.; Grant, Robert C.; Buchanan, Daniel D.; Yarmolinsky, James; Gunter, Marc J.; Zheng, Jie; Hazelwood, Emma; Vincent, Emma E. 分享 收藏
Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis 体脂分布与12种肥胖相关癌症的风险：一项孟德尔随机化分析 Hazelwood, Emma; Goudswaard, Lucy J.; Lee, Matthew A.; Vabistsevits, Marina; Pournaras, Dimitri J.; Brenner, Hermann; Buchanan, Daniel D.; Gruber, Stephen B.; Gsur, Andrea; Li, Li; Vodickova, Ludmila; Grant, Robert C.; Samadder, N. Jewel; Timpson, Nicholas J.; Gunter, Marc J.; Schuster-Bockler, Benjamin; Yarmolinsky, James; Richardson, Tom G.; Freisling, Heinz; Murphy, Neil; Vincent, Emma E. 分享 收藏
A prediction model for metachronous colorectal cancer: development and validation 同步性结直肠癌的预测模型：开发与验证 Zhang, Ye; Karahalios, Amalia; Win, Aung Ko; Makalic, Enes; Boussioutas, Alex; Buchanan, Daniel D.; Schmit, Stephanie L.; Samadder, N. Jewel; Macrae, Finlay A.; Jenkins, Mark A. 分享 收藏
Intratumoural pks+ Escherichia coli is associated with risk of metachronous colorectal cancer and adenoma development in people with Lynch syndrome 肿瘤内的pks+大肠杆菌与林奇综合征患者发生异时性结直肠癌和腺瘤发展的风险相关 Chu, Yen Lin; Georgeson, Peter; Clendenning, Mark; Mahmood, Khalid; Walker, Romy; Como, Julia; Joseland, Sharelle; Preston, Susan G.; Rice, Toni; Lynch, Brigid M.; Milne, Roger L.; Southey, Melissa C.; Giles, Graham G.; Phipps, Amanda I.; Hopper, John L.; Win, Aung K.; Rosty, Christophe; Macrae, Finlay A.; Winship, Ingrid; Jenkins, Mark A.; Buchanan, Daniel D.; Joo, Jihoon E. 分享 收藏
Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies Chalitsios, Christos V.; Markozannes, Georgios; Papagiannopoulos, Christos; Aglago, Elom K.; Berndt, Sonja I.; Buchanan, Daniel D.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Dimou, Niki; Drew, David A.; French, Amy J.; Georgeson, Peter; Giannakis, Marios; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Lynch, Brigid M.; Moreno, Victor; Newton, Christina C.; Nowak, Jonathan A.; Obon-Santacana, Mireia; Ogino, Shuji; Qu, Conghui; Schmit, Stephanie L.; Steinfelder, Robert S.; Sun, Wei; Thomas, Claire E.; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Um, Caroline Y.; Van Guelpen, Bethany; Zaidi, Syed H.; Murphy, Neil; Peters, Ulrike; Phipps, Amanda I.; Tsilidis, Konstantinos K. 分享 收藏
Functional variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with increased risk of colorectal cancer Prizment, Anna; Standafer, Abby; Qu, Conghui; Beutel, Kathleen M.; Wang, Shuo; Huang, Wen-Yi; Lindblom, Annika; Pearlman, Rachel; Van Guelpen, Bethany; Wolk, Alicja; Buchanan, Daniel D.; Grant, Robert C.; Schmit, Stephanie L.; Platz, Elizabeth A.; Joshu, Corinne E.; Couper, David J.; Peters, Ulrike; Starr, Timothy K.; Scott, Patricia; Pankratz, Nathan 分享 收藏
Association between somatic microsatellite instability, hypermutation status, and specific T cell subsets in colorectal cancer tumors Thomas, Claire E.; Takashima, Yasutoshi; Wesselink, Evertine; Ugai, Tomotaka; Steinfelder, Robert S.; Buchanan, Daniel D.; Qu, Conghui; Hsu, Li; Dias Costa, Andressa; Gallinger, Steven; Grant, Robert C.; Huyghe, Jeroen R.; Thomas, Sushma S.; Ogino, Shuji; Phipps, Amanda I.; Nowak, Jonathan A.; Peters, Ulrike 分享 收藏
Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk 更年期激素治疗: 通过家族风险评估与乳腺癌和结直肠癌的关联 Macinnis, Robert J.; Jenkins, Mark A.; Milne, Roger L.; John, Esther M.; Daly, Mary B.; Andrulis, Irene L.; Colonna, Sarah, V; Phillips, Kelly-Anne; kConFab Investigators, Loic; Le Marchand, Loic; Newcomb, Polly A.; Phipps, Amanda, I; Schmit, Stephanie L.; Macrae, Finlay A.; Buchanan, Daniel D.; Gallinger, Steven; Pai, Rish K.; Samadder, Niloy J.; Giles, Graham G.; Southey, Melissa C.; Hopper, John L.; Terry, Mary Beth 分享 收藏
Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing Aglago, Elom K.; Qu, Conghui; Harlid, Sophia; Phipps, Amanda, I; Steinfelder, Robert S.; Ogino, Shuji; Thomas, Claire E.; Hsu, Li; Toland, Amanda E.; Brenner, Hermann; Berndt, Sonja, I; Buchanan, Daniel; Campbell, Peter; Cao, Yin; Chan, Andrew; Drew, David A.; Figueiredo, Jane C.; French, Amy J.; Gallinger, Steven; Georgeson, Ter; Giannakis, Marios; Goode, Ellen L.; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Jenkins, Mark A.; Lynch, Brigid; Moreno, Victor; Murphy, Neil; Newton, Christina; Nowak, Jonathan; Obon-Santacana, Mireia; Sun, Wei; Ugai, Tomotaka; Um, Caroline Y.; Zaidi, Syed H.; Tsilidis, Konstantinos; van Guelpen, Bethany; Peters, Ulrike 分享 收藏
Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer Laskar, R. S.; Qu, C.; Huyghe, J. R.; Harrison, T.; Hayes, R. B.; Cao, Y.; Campbell, P. T.; Steinfelder, R.; Talukdar, F. R.; Brenner, H.; Ogino, S.; Brendt, S.; Bishop, D. T.; Buchanan, D. D.; Chan, A. T.; Cotterchio, M.; Gruber, S. B.; Gsur, A.; van Guelpen, B.; Jenkins, M. A.; Keku, T. O.; Lynch, B. M.; Le Marchand, L.; Martin, R. M.; McCarthy, K.; Moreno, V.; Pearlman, R.; Song, M.; Tsilidis, K. K.; Vodicka, P.; Woods, M. O.; Wu, K.; Hsu, L.; Gunter, M. J.; Peters, U.; Murphy, N. 分享 收藏
Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer 膳食纤维、水果和蔬菜摄入与结直肠癌风险的全基因组相互作用研究 Papadimitriou, Nikos; Kim, Andre; Kawaguchi, Eric S.; Morrison, John; Diez-Obrero, Virginia; Albanes, Demetrius; Berndt, Sonja I.; Bezieau, Stephane; Bien, Stephanie A.; Bishop, D. Timothy; Bouras, Emmanouil; Brenner, Hermann; Buchanan, Daniel D.; Campbell, Peter T.; Carreras-Torres, Robert; Chan, Andrew T.; Chang-Claude, Jenny; Conti, David, V; Devall, Matthew A.; Dimou, Niki; Drew, David A.; Gruber, Stephen B.; Harrison, Tabitha A.; Hoffmeister, Michael; Huyghe, Jeroen R.; Joshi, Amit D.; Keku, Temitope O.; Kundaje, Anshul; Kury, Sebastien; Le Marchand, Loic; Lewinger, Juan Pablo; Li, Li; Lynch, Brigid M.; Moreno, Victor; Newton, Christina C.; Obon-Santacana, Mireia; Ose, Jennifer; Pellatt, Andrew J.; Peoples, Anita R.; Platz, Elizabeth A.; Qu, Conghui; Rennert, Gad; Ruiz-Narvaez, Edward; Shcherbina, Anna; Stern, Mariana C.; Su, Yu-Ru; Thomas, Duncan C.; Thomas, Claire E.; Tian, Yu; Tsilidis, Konstantinos K.; Ulrich, Cornelia M.; Um, Caroline Y.; Visvanathan, Kala; Wang, Jun; White, Emily; Woods, Michael O.; Schmit, Stephanie L.; Macrae, Finlay; Potter, John D.; Hopper, John L.; Peters, Ulrike; Murphy, Neil; Hsu, Li; Gunter, Marc J.; Gauderman, W. James 分享 收藏
Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer 两个全基因组相互作用位点改变非甾体类抗炎药与结直肠癌的关系 Drew, David A.; Kim, Andre E.; Lin, Yi; Qu, Conghui; Morrison, John; Lewinger, Juan Pablo; Kawaguchi, Eric; Wang, Jun; Fu, Yubo; Zemlianskaia, Natalia; Diez-Obrero, Virginia; Bien, Stephanie A.; Dimou, Niki; Albanes, Demetrius; Baurley, James W.; Wu, Anna H.; Buchanan, Daniel D.; Potter, John D.; Prentice, Ross L.; Harlid, Sophia; Arndt, Volker; Barry, Elizabeth L.; Berndt, Sonja I.; Bouras, Emmanouil; Brenner, Hermann; Budiarto, Arif; Burnett-Hartman, Andrea; Campbell, Peter T.; Carreras-Torres, Robert; Casey, Graham; Chang-Claude, Jenny; Conti, David V.; Devall, Matthew A. M.; Figueiredo, Jane C.; Gruber, Stephen B.; Gsur, Andrea; Gunter, Marc J.; Harrison, Tabitha A.; Hidaka, Akihisa; Hoffmeister, Michael; Huyghe, Jeroen R.; Jenkins, Mark A.; Jordahl, Kristina M.; Kundaje, Anshul; Le Marchand, Loic; Li, Li; Lynch, Brigid M.; Murphy, Neil; Nassir, Rami; Newcomb, Polly A.; Newton, Christina C.; Obon-Santacana, Mireia; Ogino, Shuji; Ose, Jennifer; Pai, Rish K.; Palmer, Julie R.; Papadimitriou, Nikos; Pardamean, Bens; Pellatt, Andrew J.; Peoples, Anita R.; Platz, Elizabeth A.; Rennert, Gad; Ruiz-Narvaez, Edward; Sakoda, Lori C.; Scacheri, Peter C.; Schmit, Stephanie L.; Schoen, Robert E.; Stern, Mariana C.; Su, Yu-Ru; Thomas, Duncan C.; Tian, Yu; Tsilidis, Konstantinos K.; Ulrich, Cornelia M.; Um, Caroline Y.; van Duijnhoven, Fraenzel J. B.; Van Guelpen, Bethany; White, Emily; Hsu, Li; Moreno, Victor; Peters, Ulrike; Chan, Andrew T.; Gauderman, W. James 分享 收藏
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