Douglas R. Keene - Publications, H-index & Citations

Douglas R. Keene

Oregon Health & Science University

96H指数

311论文数

2.9W被引数

收录论文 91

发表时间

Observations of dystrophic epidermolysis bullosa patients with collagen VII NC2 truncation provide new insights into anchoring fibril assembly 对具有VII型胶原NC2截断的营养不良性大疱性表皮松解症患者的研究观察，为锚定纤维组装提供了新的见解。

Matrix Biology

IF4.8

2026-03-03

PREAI

Neha S. Momin; I. Sinem Bagci; John A. Dolorito; Sara F. Tufa; Pragya Tripathi; Kunju J. Sridhar; Douglas R. Keene; M. Peter Marinkovich

From Manual to Macro: A Reproducible Fiji Workflow for Semi-automated Collagen Fibril Diameter Quantification in Transmission Electron Microscopy 从手动到宏观：用于透射电子显微镜中半自动胶原蛋白原纤维直径定量分析的 Fiji 可复现工作流程

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

IF1.5

2026-01-01

PREAI

Bhandari, Apoorva; Mizuno, Nobuyo; Tufa, Sara F.; Sakai, Lynn Y.; Keene, Douglas R.; Shalhub, Sherene

Resolving Macromolecules by Rotary Shadowing, Negative Staining and Atomic Force Microscopy: A Comparison of Methods Applied to Identical Samples

Microscopy and Microanalysis

IF3

2025-07-25

OAAI

Sara F Tufa; Elena N Pokidysheva; Sergei P Boudko; Douglas R Keene

LB1248 Improving the therapeutic potential of intravenous recombinant collagen VII as a protein replacement therapy for recessive dystrophic epidermolysis bullosa LB1248：提高静脉用重组VII型胶原作为隐性营养不良型大疱性表皮松解症蛋白质替代疗法的治疗潜力

Journal of Investigative Dermatology

IF5.7

2025-07-21

PREAI

E. Eid; M. de Souza; K. Neelon; J.Y. Tang; M. Chen; D. Woodley; D. Keene; A. Nyström

Characterization of TGFβ1-induced tendon-like structure in the scaffold-free three-dimensional tendon cell culture system

SCIENTIFIC REPORTS

IF3.9

2024-04-25

OAAI

Koo, Bon-hyeock; Lee, Yeon-Ju; Park, Na Rae; Heo, Su Chin; Hudson, David M.; Fernandes, Aysel A.; Friday, Chet S.; Hast, Michael W.; Corr, David T.; Keene, Douglas R.; Tufa, Sara F.; Dyment, Nathaniel A.; Joeng, Kyu Sang

The Atypical Homeodomain Transcription Factor Mohawk Controls Tendon Morphogenesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

165

OAAI

Liu, Wenjin; Watson, Spencer S.; Lan, Yu; Keene, Douglas R.; Ovitt, Catherine E.; Liu, Han; Schweitzer, Ronen; Jiang, Rulang

Lysyl hydroxylase 3-mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-12-01

OAAI

Ishikawa, Yoshihiro; Taga, Yuki; Coste, Thibault; Tufa, Sara F.; Keene, Douglas R.; Mizuno, Kazunori; Tournier-Lasserve, Elisabeth; Gould, Douglas B.

EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-12-01

OAAI

Adamo, Christin S.; Beyens, Aude; Schiavinato, Alvise; Keene, Douglas R.; Tufa, Sara F.; Morgelin, Matthias; Brinckmann, Jurgen; Sasaki, Takako; Niehoff, Anja; Dreiner, Maren; Pottie, Lore; Muino-Mosquera, Laura; Gulec, Elif Yilmaz; Gezdirici, Alper; Braghetta, Paola; Bonaldo, Paolo; Wagener, Raimund; Paulsson, Mats; Bornaun, Helen; De Rycke, Riet; De Bruyne, Michiel; Baeke, Femke; Devine, Walter P.; Gangaram, Balram; Tam, Allison; Balasubramanian, Meena; Ellard, Sian; Moore, Sandra; Symoens, Sofie; Shen, Joseph; Cole, Stacey; Schwarze, Ulrike; Holmes, Kathryn W.; Hayflick, Susan J.; Wiszniewski, Wojciech; Nampoothiri, Sheela; Davis, Elaine C.; Sakai, Lynn Y.; Sengle, Gerhard; Callewaert, Bert

Anchoring Cords: A Distinct Suprastructure in the Developing Skin

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2022-11-01

OAAI

Esho, Temitope; Tufa, Sara F.; Kobbe, Birgit; Wohl, Alexander P.; Sengle, Gerhard; Paulsson, Mats; Keene, Douglas R.; Wagener, Raimund

A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis

BLOOD ADVANCES

IF7.1

2022-04-21

OAAI

Sohn, Jihee; Milosevic, Jelena; Brouse, Thomas; Aziz, Najihah; Elkhoury, Jenna; Wang, Suya; Hauschild, Alexander; van Gastel, Nick; Cetinbas, Murat; Tufa, Sara F.; Keene, Douglas R.; Sadreyev, Ruslan, I; Pu, William T.; Sykes, David B.

In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial

NATURE MEDICINE

IF50

2022-03-28

OAAI

Gurevich, Irina; Agarwal, Pooja; Zhang, PeiPei; Dolorito, John A.; Oliver, Stacie; Liu, Henry; Reitze, Nicholas; Sarma, Nikhil; Bagci, Isin Sinem; Sridhar, Kunju; Kakarla, Visesha; Yenamandra, Vamsi K.; O'Malley, Mark; Prisco, Marco; Tufa, Sara F.; Keene, Douglas R.; South, Andrew P.; Krishnan, Suma M.; Marinkovich, M. Peter

Cell autonomous TGFβ signaling is essential for stem/progenitor cell recruitment into degenerative tendons

STEM CELL REPORTS

IF5.1

2021-12-01

OAAI

Tan, Guak-Kim; Pryce, Brian A.; Stabio, Anna; Keene, Douglas R.; Tufa, Sara F.; Schweitzer, Ronen

Molecular alterations due to Col5a1 haploinsufficiency in a mouse model of classic Ehlers-Danlos syndrome

HUMAN MOLECULAR GENETICS

IF3.2

2021-11-05

OAAI

Machol, Keren; Polak, Urszula; Weisz-Hubshman, Monika; Song, I-Wen; Chen, Shan; Jiang, Ming-Ming; Chen-Evenson, Yuqing; Weis, Mary Ann E.; Keene, Douglas R.; Eyre, David R.; Lee, Brendan H.

Localized chondro-ossification underlies joint dysfunction and motor deficits in the Fkbp10 mouse model of osteogenesis imperfecta

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-06-14

OAAI

Lim, Joohyun; Lietman, Caressa; Grol, Matthew W.; Castellon, Alexis; Dawson, Brian; Adeyeye, Mary; Rai, Jyoti; Weis, MaryAnn; Keene, Douglas R.; Schweitzer, Ronen; Park, Dongsu; Eyre, David R.; Krakow, Deborah; Lee, Brendan H.

Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta

ELIFE

IF0

2021-05-26

OAAI

Grol, Matthew William; Haelterman, Nele A.; Lim, Joohyun; Munivez, Elda M.; Archer, Marilyn; Hudson, David M.; Tufa, Sara F.; Keene, Douglas R.; Lei, Kevin; Park, Dongsu; Kuzawa, Cole D.; Ambrose, Catherine G.; Eyre, David R.; Lee, Brendan H.

Reticulocalbin 3 is involved in postnatal tendon development by regulating collagen fibrillogenesis and cellular maturation

SCIENTIFIC REPORTS

IF3.9

2021-05-25

OAAI

Park, Na Rae; Shetye, Snehal S.; Bogush, Igor; Keene, Douglas R.; Tufa, Sara; Hudson, David M.; Archer, Marilyn; Qin, Ling; Soslowsky, Louis J.; Dyment, Nathaniel A.; Joeng, Kyu Sang

QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2021-04-01

OAAI

Bornert, Olivier; Hogervorst, Marieke; Nauroy, Pauline; Bischof, Johannes; Swildens, Jim; Athanasiou, Ioannis; Tufa, Sara F.; Keene, Douglas R.; Kiritsi, Dimitra; Hainzl, Stefan; Murauer, Eva M.; Marinkovich, M. Peter; Platenburg, Gerard; Hausser, Ingrid; Wally, Verena; Ritsema, Tita; Koller, Ulrich; Haisma, Elisabeth M.; Nystroem, Alexander

Type I and type V procollagen triple helix uses different subsets of the molecular ensemble for lysine posttranslational modifications in the rER

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Ishikawa, Yoshihiro; Taga, Yuki; Zientek, Keith; Mizuno, Nobuyo; Salo, Antti M.; Semenova, Olesya; Tufa, Sara F.; Keene, Douglas R.; Holden, Paul; Mizuno, Kazunori; Gould, Douglas B.; Myllyharju, Johanna; Bachinger, Hans Peter

Immune tolerance of allogeneic haematopoietic cell transplantation supports donor epidermal grafting of recessive dystrophic epidermolysis bullosa chronic wounds

BRITISH JOURNAL OF DERMATOLOGY

IF9.6

2020-12-14

OAAI

Ebens, C. L.; McGrath, J. A.; Riedl, J. A.; Keith, A. R.; Lilja, G.; Rusch, S.; Keene, D. R.; Tufa, S. F.; Riddle, M. J.; Shanley, R.; Van Heest, A. E.; Tolar, J.

Tgfβ signaling is critical for maintenance of the tendon cell fate

ELIFE

IF0

2020-01-21

OAAI

Tan, Guak-Kim; Pryce, Brian A.; Stabio, Anna; Brigande, John V.; Wang, ChaoJie; Xia, Zheng; Tufa, Sara F.; Keene, Douglas R.; Schweitzer, Ronen

研究方向