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M

Mark Clendenning

University of Melbourne
H指数:51
被引数:9,620

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The germline POLD1 c.1420 C > A (p.Leu474Ile) variant segregates with endometrial cancer, colorectal cancer and colonic polyps demonstrating hypermutation and defective POLD1 mutational signatures

生殖系POLD1 c.1420 C > A (p.Leu474Ile)变异与子宫内膜癌、结直肠癌和结肠息肉共存，表现出超突变和POLD1突变谱异常的特征。

FAMILIAL CANCER
IF2
2025-11-100
PRE
Buchanan, Daniel D.; Georgeson, Peter; Walker, Romy; Joo, Jihoon E.; Clendenning, Mark; Como, Julia; O'keeffe, Ryan; Prisc, Alysha; Chu, Yen Lin; Jenkins, Mark A.; Rosty, Christophe; Winship, Ingrid M.; Macrae, Finlay A.; Ip, Emilia; Harris, Rebecca; Goodwin, Annabel; Mahmood, Khalid
Intratumoural pks+ Escherichia coli is associated with risk of metachronous colorectal cancer and adenoma development in people with Lynch syndrome

肿瘤内的pks+大肠杆菌与林奇综合征患者发生异时性结直肠癌和腺瘤发展的风险相关

EBIOMEDICINE
IF10.8
2025-04-010
OAAI
Chu, Yen Lin; Georgeson, Peter; Clendenning, Mark; Mahmood, Khalid; Walker, Romy; Como, Julia; Joseland, Sharelle; Preston, Susan G.; Rice, Toni; Lynch, Brigid M.; Milne, Roger L.; Southey, Melissa C.; Giles, Graham G.; Phipps, Amanda I.; Hopper, John L.; Win, Aung K.; Rosty, Christophe; Macrae, Finlay A.; Winship, Ingrid; Jenkins, Mark A.; Buchanan, Daniel D.; Joo, Jihoon E.
Intratumoral presence of the genotoxic gut bacteria pks+E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with clinicopathological and molecular features of colorectal cancer
BRITISH JOURNAL OF CANCER
IF6.8
2024-01-1012
OA
Joo, Jihoon E.; Chu, Yen Lin; Georgeson, Peter; Walker, Romy; Mahmood, Khalid; Clendenning, Mark; Meyers, Aaron L.; Como, Julia; Joseland, Sharelle; Preston, Susan G.; Diepenhorst, Natalie; Toner, Julie; Ingle, Danielle J.; Sherry, Norelle L.; Metz, Andrew; Lynch, Brigid M.; Milne, Roger L.; Southey, Melissa C.; Hopper, John L.; Win, Aung Ko; Macrae, Finlay A.; Winship, Ingrid M.; Rosty, Christophe; Jenkins, Mark A.; Buchanan, Daniel D.
Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers
CLINICAL EPIGENETICS
IF4.4
2023-06-034
OAAI
Joo, Jihoon E.; Mahmood, Khalid; Walker, Romy; Georgeson, Peter; Candiloro, Ida; Clendenning, Mark; Como, Julia; Joseland, Sharelle; Preston, Susan; Graversen, Lise; Wilding, Mathilda; Field, Michael; Lemon, Michelle; Wakeling, Janette; Marfan, Helen; Susman, Rachel; Isbister, Joanne; Edwards, Emma; Bowman, Michelle; Kirk, Judy; Ip, Emilia; McKay, Lynne; Antill, Yoland; Hopper, John L.; Boussioutas, Alex; Macrae, Finlay A.; Dobrovic, Alexander; Jenkins, Mark A.; Rosty, Christophe; Winship, Ingrid M.; Buchanan, Daniel D.
A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome
JOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
2023-04-267
OAAI
Walker, Romy; Mahmood, Khalid E.; Joo, Jihoon; Clendenning, Mark; Georgeson, Peter; Como, Julia; Joseland, Sharelle G.; Preston, Susan; Antill, Yoland; Austin, Rachel; Boussioutas, Alex; Bowman, Michelle; Burke, Jo; Campbell, Ainsley; Daneshvar, Simin; Edwards, Emma; Gleeson, Margaret; Goodwin, Annabel T.; Harris, Marion; Henderson, Alex; Higgins, Megan L.; Hopper, John A.; Hutchinson, Ryan; Ip, Emilia; Isbister, Joanne; Kasem, Kais; Marfan, Helen; Milnes, Di; Ng, Annabelle; Nichols, Cassandra; O'Connell, Shona; Pachter, Nicholas J.; Pope, Bernard; Poplawski, Nicola; Ragunathan, Abiramy; Smyth, Courtney; Spigelman, Allan; Storey, Kirsty; Susman, Rachel A.; Taylor, Jessica; Warwick, Linda; Wilding, Mathilda; Williams, Rachel K.; Win, Aung D.; Walsh, Michael A.; Macrae, Finlay A.; Jenkins, Mark; Rosty, Christophe M.; Winship, Ingrid D.; Buchanan, Daniel
Evaluating Multiple Next-Generation Sequencing-Derived Tumor Features to Accurately Predict DNA Mismatch Repair Status
JOURNAL OF MOLECULAR DIAGNOSTICS
IF3.4
2023-02-015
OAAI
Walker, Romy; Georgeson, Peter; Mahmood, Khalid; Joo, Jihoon E.; Makalic, Enes; Clendenning, Mark; Como, Julia; Preston, Susan; Joseland, Sharelle; Pope, Bernard J.; Hutchinson, Ryan A.; Kasem, Kais; Walsh, Michael D.; Macrae, Finlay A.; Win, Aung K.; Hopper, John L.; Mouradov, Dmitri; Gibbs, Peter; Sieber, Oliver M.; O'Sullivan, Dylan E.; Brenner, Darren R.; Gallinger, Steven; Jenkins, Mark A.; Rosty, Christophe; Winship, Ingrid M.; Buchanan, Daniel D.
Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures
NATURE COMMUNICATIONS
IF15.7
2022-06-0610
OAAI
Georgeson, Peter; Harrison, Tabitha A.; Pope, Bernard J.; Zaidi, Syed H.; Qu, Conghui; Steinfelder, Robert S.; Lin, Yi; Joo, Jihoon E.; Mahmood, Khalid; Clendenning, Mark; Walker, Romy; Amitay, Efrat L.; Berndt, Sonja, I; Brenner, Hermann; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Chang-Claude, Jenny; Doheny, Kimberly F.; Drew, David A.; Figueiredo, Jane C.; French, Amy J.; Gallinger, Steven; Giannakis, Marios; Giles, Graham G.; Gsur, Andrea; Gunter, Marc J.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Limburg, Paul; Manson, JoAnn E.; Moreno, Victor; Nassir, Rami; Nowak, Jonathan A.; Obon-Santacana, Mireia; Ogino, Shuji; Phipps, Amanda, I; Potter, John D.; Schoen, Robert E.; Sun, Wei; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Macrae, Finlay A.; Rosty, Christophe; Hudson, Thomas J.; Jenkins, Mark A.; Thibodeau, Stephen N.; Winship, Ingrid M.; Peters, Ulrike; Buchanan, Daniel D.
Germline MBD4 deficiency causes a multi-tumor predisposition syndrome
AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2022-05-0129
OAAI
Palles, Claire; West, Hannah D.; Chew, Edward; Galavotti, Sara; Flensburg, Christoffer; Grolleman, Judith E.; Jansen, Erik A. M.; Curley, Helen; Chegwidden, Laura; Arbe-Barnes, Edward H.; Lander, Nicola; Truscott, Rebekah; Pagan, Judith; Bajel, Ashish; Sherwood, Kitty; Martin, Lynn; Thomas, Huw; Georgiou, Demetra; Fostira, Florentia; Goldberg, Yael; Adams, David J.; van der Biezen, Simone A. M.; Christie, Michael; Clendenning, Mark; Thomas, Laura E.; Deltas, Constantinos; Dimovski, Aleksandar J.; Dymerska, Dagmara; Lubinski, Jan; Mahmood, Khalid; van der Post, Rachel S.; Sanders, Mathijs; Weitz, Jurgen; Taylor, Jenny C.; Turnbull, Clare; Vreede, Lilian; van Wezel, Tom; Whalley, Celina; Arnedo-Pac, Claudia; Caravagna, Giulio; Cross, William; Chubb, Daniel; Frangou, Anna; Gruber, Andreas J.; Kinnersley, Ben; Noyvert, Boris; Church, David; Graham, Trevor; Houlston, Richard; Lopez-Bigas, Nuria; Sottoriva, Andrea; Wedge, David; Jenkins, Mark A.; Kuiper, Roland P.; Roberts, Andrew W.; Cheadle, Jeremy P.; Ligtenberg, Marjolijn J. L.; Hoogerbrugge, Nicoline; Koelzer, Viktor H.; Rivas, Andres Dacal; Winship, Ingrid M.; Ponte, Clara Ruiz; Buchanan, Daniel D.; Power, Derek G.; Green, Andrew; Tomlinson, Ian P. M.; Sampson, Julian R.; Majewski, Ian J.; de Voer, Richarda M.
Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome
BRITISH JOURNAL OF CANCER
IF6.8
2019-09-258
OAAI
Dashti, S. Ghazaleh; Li, Wing Yan; Buchanan, Daniel D.; Clendenning, Mark; Rosty, Christophe; Winship, Ingrid M.; Macrae, Finlay A.; Giles, Graham G.; Hardikar, Sheetal; Hua, Xinwei; Thibodeau, Stephen N.; Figueiredo, Jane C.; Casey, Graham; Haile, Robert W.; Gallinger, Steven; Le Marchand, Loic; Newcomb, Polly A.; Potter, John D.; Lindor, Noralane M.; Hopper, John L.; Jenkins, Mark A.; Win, Aung Ko
Identification of nine new susceptibility loci for endometrial cancer

九个新的子宫内膜癌易感位点的鉴定

NATURE COMMUNICATIONS
IF15.7
2018-08-09177
OAAI
O'Mara, Tracy A.; Glubb, Dylan M.; Amant, Frederic; Annibali, Daniela; Ashton, Katie; Attia, John; Auer, Paul L.; Beckmann, Matthias W.; Black, Amanda; Bolla, Manjeet K.; Brauch, Hiltrud; Brenner, Hermann; Brinton, Louise; Buchanan, Daniel D.; Burwinkel, Barbara; Chang-Claude, Jenny; Chanock, Stephen J.; Chen, Chu; Chen, Maxine M.; Cheng, Timothy H. T.; Clarke, Christine L.; Clendenning, Mark; Cook, Linda S.; Couch, Fergus J.; Cox, Angela; Crous-Bous, Marta; Czene, Kamila; Day, Felix; Dennis, Joe; Depreeuw, Jeroen; Doherty, Jennifer Anne; Dork, Thilo; Dowdy, Sean C.; Duerst, Matthias; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Friedenreich, Christine M.; Fritschi, Lin; Fung, Jenny; Garcia-Closas, Montserrat; Gaudet, Mia M.; Giles, Graham G.; Goode, Ellen L.; Gorman, Maggie; Haiman, Christopher A.; Hall, Per; Hankison, Susan E.; Healey, Catherine S.; Hein, Alexander; Hillemanns, Peter; Hodgson, Shirley; Hoivik, Erling A.; Holliday, Elizabeth G.; Hopper, John L.; Hunter, David J.; Jones, Angela; Krakstad, Camilla; Kristensen, Vessela N.; Lambrechts, Diether; Le Marchand, Loic; Liang, Xiaolin; Lindblom, Annika; Lissowska, Jolanta; Long, Jirong; Lu, Lingeng; Magliocco, Anthony M.; Martin, Lynn; McEvoy, Mark; Meindl, Alfons; Michailidou, Kyriaki; Milne, Roger L.; Mints, Miriam; Montgomery, Grant W.; Nassir, Rami; Olsson, Haekan; Orlow, Irene; Otton, Geoffrey; Palles, Claire; Perry, John R. B.; Peto, Julian; Pooler, Loreall; Prescott, Jennifer; Proietto, Tony; Rebbeck, Timothy R.; Risch, Harvey A.; Rogers, Peter A. W.; Ruebner, Matthias; Runnebaum, Ingo; Sacerdote, Carlotta; Sarto, Gloria E.; Schumacher, Fredrick; Scott, Rodney J.; Setiawan, V. Wendy; Shah, Mitul; Sheng, Xin; Shu, Xiao-Ou; Southey, Melissa C.; Swerdlow, Anthony J.; Tham, Emma; Trovik, Jone; Turman, Constance; Tyrer, Jonathan P.; Vachon, Celine; Vanden Berg, David; Vanderstichele, Adriaan; Wang, Zhaoming; Webb, Penelope M.; Wentzensen, Nicolas; Werner, Henrica M. J.; Winham, Stacey J.; Wolk, Alicja; Xia, Lucy; Xiang, Yong-Bing; Yang, Hannah P.; Yu, Herbert; Zheng, Wei; Pharoah, Paul D. P.; Dunning, Alison M.; Kraft, Peter; De Vivo, Immaculata; Tomlinson, Ian; Easton, Douglas F.; Spurdle, Amanda B.; Thompson, Deborah J.
Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype

饮酒、吸烟、体力活动和肥胖与结直肠癌分期、解剖部位和肿瘤分子亚型的关系

INTERNATIONAL JOURNAL OF CANCER
IF4.7
2017-10-0482
OAAI
Jayasekara, Harindra; English, Dallas R.; Haydon, Andrew; Hodge, Allison M.; Lynch, Brigid M.; Rosty, Christophe; Williamson, Elizabeth J.; Clendenning, Mark; Southey, Melissa C.; Jenkins, Mark A.; Room, Robin; Hopper, John L.; Milne, Roger L.; Buchanan, Daniel D.; Giles, Graham G.; MacInnis, Robert J.
Double somatic mutations as a cause of tumor mismatch repair-deficiency in population-based colorectal and endometrial cancer with Lynch-like syndrome
CANCER RESEARCH
IF16.6
2017-07-012
PRE
Buchanan, Daniel D.; Clendenning, Mark; Jayasekara, Harindra; Joo, Jihoon E.; Wong, Ee M.; Southey, Melissa C.; Walters, Rhiannon J.; Pope, Bernard J.; Win, Aung K.; Hopper, John L.; Jenkins, Mark A.; Milne, Roger L.; Giles, Graham G.; English, Dallas R.; Macrae, Finlay A.; Spurdle, Amanda B.; Winship, Ingrid M.; Rosty, Christophe
Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study

TNM系统以外的II期和III期结肠癌总生存期的预测: 一项回顾性，汇总的生物标志物研究

ANNALS OF ONCOLOGY
IF65.4
2017-05-01177
OAAI
Dienstmann, R.; Mason, M. J.; Sinicrope, F. A.; Phipps, A. I.; Tejpar, S.; Nesbakken, A.; Danielsen, S. A.; Sveen, A.; Buchanan, D. D.; Clendenning, M.; Rosty, C.; Bot, B.; Alberts, S. R.; Jessup, J. Milburn; Lothe, R. A.; Delorenzi, M.; Newcomb, P. A.; Sargent, D.; Guinney, J.
Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

大肠癌的主要基因和多基因的患病率和外显率

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
2017-03-01344
OAAI
Win, Aung Ko; Jenkins, Mark A.; Dowty, James G.; Antoniou, Antonis C.; Lee, Andrew; Giles, Graham G.; Buchanan, Daniel D.; Clendenning, Mark; Rosty, Christophe; Ahnen, Dennis J.; Thibodeau, Stephen N.; Casey, Graham; Gallinger, Steven; Le Marchand, Loic; Haile, Robert W.; Potter, John D.; Zheng, Yingye; Lindor, Noralane M.; Newcomb, Polly A.; Hopper, John L.; Maclnnis, Robert J.
Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
2017-03-0136
OAAI
Dashti, S. Ghazaleh; Buchanan, Daniel D.; Jayasekara, Harindra; Ouakrim, Driss Ait; Clendenning, Mark; Rosty, Christophe; Winship, Ingrid M.; Macrae, Finlay A.; Giles, Graham G.; Parry, Susan; Casey, Graham; Haile, Robert W.; Gallinger, Steven; Le Marchand, Loic; Thibodeau, Stephen N.; Lindor, Noralane M.; Newcomb, Polly A.; Potter, John D.; Baron, John A.; Hopper, John L.; Jenkins, Mark A.; Win, Aung Ko
Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
IF3.4
2017-02-2145
OAAI
Buchanan, Daniel D.; Clendenning, Mark; Rosty, Christophe; Eriksen, Stine V.; Walsh, Michael D.; Walters, Rhiannon J.; Thibodeau, Stephen N.; Stewart, Jenna; Preston, Susan; Win, Aung Ko; Flander, Louisa; Ouakrim, Driss Ait; Macrae, Finlay A.; Boussioutas, Alex; Winship, Ingrid M.; Giles, Graham G.; Hopper, John L.; Southey, Melissa C.; English, Dallas; Jenkins, Mark A.

研究方向

暂未获取到该数据
D
Daniel D. Buchanan
H 指数:78论文数:889被引数:2.3万
M
Mark A. Jenkins
H 指数:99论文数:1,169被引数:3.8万
J
John L. Hopper
H 指数:0论文数:6被引数:336
C
Christophe Rosty
H 指数:60论文数:287被引数:1.3万
A
Aung Ko Win
H 指数:61论文数:477被引数:1.2万
I
Ingrid Winship
H 指数:60论文数:495被引数:1.7万
F
Finlay Macrae
H 指数:70论文数:586被引数:2.0万
G
Graham G. Giles
H 指数:164论文数:2,399被引数:12.2万
N
Noralane M. Lindor
H 指数:100论文数:613被引数:3.6万
P
Polly A. Newcomb
H 指数:104论文数:1,069被引数:4.5万