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Adjuvant personalized multivalent neoantigen DNA vaccination for MGMT unmethylated glioblastoma: a phase 1 trial 佐剂个性化多价新抗原DNA疫苗接种用于MGMT未甲基化胶质母细胞瘤：一项1期临床试验 Garfinkle, Elizabeth A. R.; Perales-Linares, Renzo; Gimple, Ryan C.; Livingstone, Alexandra J.; Roberts, Kaleigh F.; Butt, Omar H.; Goedegebuure, S. Peter; McLellan, Michael D.; Chang, Gue Su; Hundal, Jasreet; Yan, Jian; Navarro, Jaye B.; Paxton, Sophia A.; Chattopadhyay, Srestha; Cooch, Neil; Perales-Puchalt, Alfredo; Stavroulaki, Konstantina; Rochestie, Sarah; Peters, Joann; Junker, Beth; Campian, Jian L.; Chheda, Milan G.; Chicoine, Michael R.; Kim, Albert H.; Willie, Jon T.; Zipfel, Gregory J.; Dowling, Joshua L.; Miller, Christopher A.; Griffith, Obi L.; Griffith, Malachi; Gillanders, William E.; Miller, Katherine E.; Mardis, Elaine R.; Sardesai, Niranjan Y.; Dunn, Gavin P.; Johanns, Tanner M. 分享 收藏
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NT-I7, A LONG-ACTING INTERLEUKIN-7, PROMOTES ACTIVATION, CYTOTOXIC FUNCTION, AND SELECTIVE CLONOTYPE EXPANSION OF CD8+T CELLS IN PATIENTS WITH HIGH GRADE GLIOMAS Barozinsky, Kaiden; Foltz, Jennifer A.; Butt, Omar H.; Zhou, Alice Y.; Singhal, Kartik; Griffith, Obi; Griffith, Malachi; Etter, Kelsey; Grote, Cierra; Luo, Jingqin; Nehring, Leslie; Katumba, Ruth; Ferrando-Martinez, Sara; Stermer, Kristina; Lee, Byung Ha; Johanns, Tanner; Huang, Jiayi; Dipersio, John; Chheda, Milan; Fehniger, Todd; Campian, Jian L. 分享 收藏
A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges 数据驱动的癌症研究和护理新时代: 机遇与挑战 Gomez, Felicia; Danos, Arpad M.; Del Fiol, Guilherme; Madabhushi, Anant; Tiwari, Pallavi; Mcmichael, Joshua F.; Bakas, Spyridon; Bian, Jiang; Davatzikos, Christos; Fertig, Elana J.; Kalpathy-Cramer, Jayashree; Kenney, Johanna; Savova, Guergana K.; Yetisgen, Meliha; Van Allen, Eliezer M.; Warner, Jeremy L.; Prior, Fred; Griffith, Malachi; Griffith, Obi L. 分享 收藏
Whole-genome sequences reveal zygotic composition in chimeric twins Yoon, Christopher J.; Nam, Chang Hyun; Kim, Taewoo; Lee, Jeong Seok; Kim, Ryul; Yi, Kijong; Koh, June-Young; Kim, Jiye; Won, Hyein; Oh, Ji Won; Griffith, Obi L.; Griffith, Malachi; Sung, Joohon; Kim, Tae Yeul; Cho, Duck; Choi, Ji Seon; Ju, Young Seok 分享 收藏
Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation Foltz, Jennifer A.; Tran, Jennifer; Wong, Pamela; Fan, Changxu; Schmidt, Evelyn; Fisk, Bryan; Becker-Hapak, Michelle; Russler-Germain, David A.; Johnson, Jeanette; Marin, Nancy D.; Cubitt, Celia C.; Pence, Patrick; Rueve, Joseph; Pureti, Sushanth; Hwang, Kimberly; Gao, Feng; Zhou, Alice Y.; Foster, Mark; Schappe, Timothy; Marsala, Lynne; Berrien-Elliott, Melissa M.; Cashen, Amanda F.; Bednarski, Jeffrey J.; Fertig, Elana; Griffith, Obi L.; Griffith, Malachi; Wang, Ting; Petti, Allegra A.; Fehniger, Todd A. 分享 收藏
Single-cell T-cell receptor repertoire profiling in dogs Hoang, My H.; Skidmore, Zachary L.; Rindt, Hans; Chu, Shirley; Fisk, Bryan; Foltz, Jennifer A.; Fronick, Catrina; Fulton, Robert; Zhou, Mingyi; Bivens, Nathan J.; Reinero, Carol N.; Fehniger, Todd A.; Griffith, Malachi; Bryan, Jeffrey N.; Griffith, Obi L. 分享 收藏
DGIdb 5.0: rebuilding the drug-gene interaction database for precision medicine and drug discovery platforms Cannon, Matthew; Stevenson, James; Stahl, Kathryn; Basu, Rohit; Coffman, Adam; Kiwala, Susanna; McMichael, Joshua F.; Kuzma, Kori; Morrissey, Dorian; Cotto, Kelsy; Mardis, Elaine R.; Griffith, Obi L.; Griffith, Malachi; Wagner, Alex H. 分享 收藏
Mutations associated with progression in follicular lymphoma predict inferior outcomes at diagnosis: Alliance A151303 Russler-Germain, David A.; Krysiak, Kilannin; Ramirez, Cody; Mosior, Matthew; Watkins, Marcus P.; Gomez, Felicia; Skidmore, Zachary L.; Trani, Lee; Gao, Feng; Geyer, Susan; Cashen, Amanda F.; Mehta-Shah, Neha; Kahl, Brad S.; Bartlett, Nancy L.; Alderuccio, Juan P.; Lossos, Izidore S.; Ondrejka, Sarah L.; Hsi, Eric D.; Martin, Peter; Leonard, John P.; Griffith, Malachi; Griffith, Obi L.; Fehniger, Todd A. 分享 收藏
T-BET and EOMES sustain mature human NK cell identity and antitumor function Wong, Pamela; Foltz, Jennifer A.; Chang, Lily; Neal, Carly C.; Yao, Tony; Cubitt, Celia C.; Tran, Jennifer; Kersting-Schadek, Samantha; Palakurty, Sathvik; Jaeger, Natalia; Russler-Germain, David A.; Marin, Nancy D.; Gang, Margery; Wagner, Julia A.; Zhou, Alice Y.; Jacobs, Miriam T.; Foster, Mark; Schappe, Timothy; Marsala, Lynne; McClain, Ethan; Pence, Patrick; Becker-Hapak, Michelle; Fisk, Bryan; Petti, Allegra A.; Griffith, Obi L.; Griffith, Malachi; Berrien-Elliott, Melissa M.; Fehniger, Todd A. 分享 收藏
Brief IL-12, IL-15, IL-18 activation drives the acquisition of two distinct memory-like NK cell states Foltz, Jennifer Ann; Tran, Jennifer; Fisk, Bryan; Wong, Pamela; Khan, Saad M.; Berrien-Elliott, Melissa M.; Becker-Hapak, Michelle; Russler-Germain, David A.; Marsala, Lynne; Bednarski, Jeffrey J.; Zimmerman, Clare; Cubitt, Celia C.; Marin, Nancy D.; Zhou, Alice Y.; Jacobs, Miriam T.; Foster, Mark; Schappe, Timothy; Pence, Patrick; Cashen, Amanda; Griffith, Obi L.; Griffith, Malachi; Petti, Allegra A.; Fehniger, Todd A. 分享 收藏
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Computational prediction of MHC anchor locations guides neoantigen identification and prioritization Xia, Huiming; McMichael, Joshua; Becker-Hapak, Michelle; Onyeador, Onyinyechi C.; Buchli, Rico; McClain, Ethan; Pence, Patrick; Supabphol, Suangson; Richters, Megan M.; Basu, Anamika; Ramirez, Cody A.; Puig-Saus, Cristina; Cotto, Kelsy C.; Freshour, Sharon L.; Hundal, Jasreet; Kiwala, Susanna; Goedegebuure, S. Peter; Johanns, Tanner M.; Dunn, Gavin P.; Ribas, Antoni; Miller, Christopher A.; Gillanders, William E.; Fehniger, Todd A.; Griffith, Obi L.; Griffith, Malachi 分享 收藏
Comprehensive single-cell transcriptomic analysis of a mouse model of bladder cancer identifies endothelial cells as a principal target of interferon gamma during response to combined PD-1, CTLA-4 immune checkpoint inhibitor treatment Freshour, Sharon L.; Fisk, Bryan; Chen, Timothy Hung-Po; Shen, Haolin; Mosior, Matthew; Fronick, Catrina; Bolzenius, Jennifer; Griffith, Obi L.; Arora, Vivek; Griffith, Malachi 分享 收藏
Autologous humanized PDX modeling for immuno-oncology recapitulates the human tumor microenvironment Chiorazzi, Michael; Martinek, Jan; Krasnick, Bradley; Zheng, Yunjiang; Robbins, Keenan; Qu, Rihao; Kaufmann, Gabriel; Skidmore, Zachary; Henze, Laura; Brosecke, Frederic; Adonyi, Adam; Zhao, Jun; Shan, Liang; Sefik, Esen; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S. Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fertuzinhos, Sofia; Garcia-Milian, Roland; Boffa, Daniel; Detterbeck, Frank; Dhanasopon, Andrew; Blasberg, Justin; Judson, Benjamin; Gettinger, Scott; Politi, Katerina; Kluger, Yuval; Palucka, A. Karolina; Fields, Ryan; Flavell, Richard A. 分享 收藏
ClinGen Somatic and CIViC collaborate to comprehensively evaluate somatic variants in cancer Saliba, Jason; Danos, Arpad; Krysiak, Kilannin; Coffman, Adam; Kiwala, Susanna; McMichael, Joshua; Grisdale, Cameron J.; King, Ian; Selvarajah, Shamini; Xu, Xinjie; Kanagal-Shamanna, Rashmi; Satgunaseelan, Laveniya; Meredith, David; Evans, Mark; Mullighan, Charles G.; Akkari, Yassmine; Raca, Gordana; Roy, Angshumoy; Wagner, Alex H.; Govindan, Ramaswamy; Griffith, Obi L.; Griffith, Malachi 分享 收藏
Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer Cotto, Kelsy C.; Feng, Yang-Yang; Ramu, Avinash; Richters, Megan; Freshour, Sharon L.; Skidmore, Zachary L.; Xia, Huiming; McMichael, Joshua F.; Kunisaki, Jason; Campbell, Katie M.; Chen, Timothy Hung-Po; Rozycki, Emily B.; Adkins, Douglas; Devarakonda, Siddhartha; Sankararaman, Sumithra; Lin, Yiing; Chapman, William C.; Maher, Christopher A.; Arora, Vivek; Dunn, Gavin P.; Uppaluri, Ravindra; Govindan, Ramaswamy; Griffith, Obi L.; Griffith, Malachi 分享 收藏
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