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K

Kento Tazawa

Graduate School of Medical and Dental Sciences
H指数:11
被引数:314

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Temporal immunohistochemical analysis of macrophage, neutrophil, and osteoclast dynamics during metformin-mediated suppression of experimentally induced apical periodontitis in mice

在小鼠实验性诱导的根尖周炎中，二甲双胍介导抑制期间巨噬细胞、中性粒细胞和破骨细胞动态的时间免疫组化分析

BMC Oral Health
IF3.1
2026-08-180
OA
Faisal Alghamdi; Kento Tazawa; Chunmei Ren; Shuaichen Liu; Chuyi Zhou; Junnosuke Takahashi; Risa Ohshima; Masaharu Ishidori; Toka Fukubayashi; Nobuyuki Kawashima; Takashi Okiji; Yoshio Yahata
Metformin suppresses periapical bone resorption in a mouse model of apical periodontitis in vivo and inhibits RANKL-induced osteoclastogenesis in vitro

二甲双胍在体内抑制根尖周炎小鼠模型中的根尖骨吸收，并在体外抑制RANKL诱导的破骨细胞生成

Journal of Oral Biosciences
IF2.3
2026-07-040
PRE
Faisal Alghamdi; Chunmei Ren; Kento Tazawa; Shuaichen Liu; Chuyi Zhou; Junnosuke Takahashi; Masaharu Ishidori; Risa Ohshima; Nobuyuki Kawashima; Takashi Okiji; Yoshio Yahata
Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7 through the AMPK-mTOR-NF-κB pathway

二甲双胍通过AMPK-mTOR-NF-κB通路减轻根尖周炎小鼠的牙槽骨破坏，并在脂多糖刺激的RAW264.7细胞中抑制促炎细胞因子的合成

Frontiers in Immunology
IF5.9
2025-08-020
OA
Chunmei Ren; Kento Tazawa; Nobuyuki Kawashima; Risa Ohshima; Yamato Okada; Shihan Wang; Ziniu Yu; Peifeng Han; Yujin Ohsugi; Sayaka Katagiri; Takashi Okiji

研究方向

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T
Takashi Okiji
H 指数:39论文数:261被引数:5,765
N
Nobuyuki Kawashima
H 指数:25论文数:92被引数:2,346
K
Keisuke Nara
H 指数:11论文数:21被引数:659
S
Sonoko Noda
H 指数:11论文数:21被引数:413
K
Kentaro Hashimoto
H 指数:14论文数:75被引数:529
M
Mayuko Fujii
H 指数:9论文数:18被引数:226
P
Peifeng Han
H 指数:5论文数:14被引数:116
M
Masashi Kuramoto
H 指数:14论文数:23被引数:749
Z
Ziniu Yu
H 指数:3论文数:8被引数:47
F
Faisal Alghamdi
H 指数:11论文数:82被引数:745