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Nivolumab plus relatlimab and nivolumab plus ipilimumab for patients with advanced renal cell carcinoma: results from the open-label, randomised, phase II FRACTION-RCC trial Nivolumab联合relatlimab和nivolumab联合ipilimumab治疗晚期肾细胞癌患者: 开放标签，随机，II期分次RCC试验的结果 Choueiri, T. K.; Kuzel, T. M.; Tykodi, S. S.; Verzoni, E.; Kluger, H.; Nair, S.; Perets, R.; George, S.; Gurney, H.; Pachynski, R. K.; Folefac, E.; Castonguay, V.; Lee, C. -h.; Vaishampayan, U.; Miller Jr, W. H.; Bhagavatheeswaran, P.; Wang, Y.; Gupta, S.; Desilva, H.; Lee, C. -w.; Escudier, B.; Motzer, R. J. 分享 收藏
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Myeloid differentiation factor-2/LY96, a potential predictive biomarker of metastasis and poor outcomes in prostate cancer: clinical implications as a potential therapeutic target Ferrari, Marina G.; Jimenez-Uribe, Alexis P.; Wang, Li; Hoeppner, Luke H.; Murugan, Paari; Hahm, Eunsil; Yu, Jindan; Kuzel, Timothy M.; Gradilone, Sergio A.; Mansini, Adrian P. 分享 收藏
Phase 1 dose-escalation study of SEA-CD40: a non-fucosylated CD40 agonist, in advanced solid tumors and lymphomas SEA-CD40的1期剂量递增研究: 非岩藻糖基化CD40激动剂，用于晚期实体瘤和淋巴瘤 Coveler, Andrew L.; Smith, David C.; Phillips, Tycel; Curti, Brendan D.; Goel, Sanjay; Mehta, Amitkumar N.; Kuzel, Timothy M.; Markovic, Svetomir N.; Rixe, Olivier; Bajor, David L.; Gajewski, Thomas F.; Gutierrez, Martin; Lee, Hun Ju; Gopal, Ajay K.; Caimi, Paolo; Heath, Elisabeth, I; Thompson, John A.; Ansari, Sahar; Jacquemont, Celine; Topletz-Erickson, Ariel; Zhou, Peigen; Schmitt, Michael W.; Grilley-Olson, Juneko E. 分享 收藏
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FRACTION-RCC: nivolumab plus ipilimumab for advanced renal cell carcinoma after progression on immuno-oncology therapy 分数-RCC: nivolumab联合ipilimumab治疗免疫肿瘤治疗进展后的晚期肾细胞癌 Choueiri, Toni K.; Kluger, Harriet; George, Saby; Tykodi, Scott S.; Kuzel, Timothy M.; Perets, Ruth; Nair, Suresh; Procopio, Giuseppe; Carducci, Michael A.; Castonguay, Vincent; Folefac, Edmund; Lee, Chung-Han; Hotte, Sebastien J.; Miller, Wilson H.; Saggi, Shruti Shally; Lee, Chung-Wei; Desilva, Heshani; Bhagavatheeswaran, Prabhu; Motzer, Robert J.; Escudier, Bernard 分享 收藏
Efficacy and Safety of Topical Hypericin Photodynamic Therapy for Early-Stage Cutaneous T-Cell Lymphoma (Mycosis Fungoides) The FLASH Phase 3 Randomized Clinical Trial 局部金丝桃素光动力疗法治疗早期皮肤T细胞淋巴瘤 (蕈样肉芽肿) 的疗效和安全性FLASH 3期随机临床试验 Kim, Ellen J.; Mangold, Aaron R.; DeSimone, Jennifer A.; Wong, Henry K.; Seminario-Vidal, Lucia; Guitart, Joan; Appel, James; Geskin, Larisa; Lain, Edward; Korman, Neil J.; Zeitouni, Nathalie; Nikbakht, Neda; Dawes, Kenneth; Akilov, Oleg; Carter, Joi; Shinohara, Michi; Kuzel, Timothy M.; Piette, Warren; Bhatia, Neal; Musiek, Amy; Pariser, David; Kim, Youn H.; Elston, Dirk; Boh, Erin; Duvic, Madeleine; Huen, Auris; Pacheco, Theresa; Zwerner, Jeffrey P.; Lee, Seung Tae; Girardi, Michael; Querfeld, Christiane; Bohjanen, Kimberly; Olsen, Elise; Wood, Gary S.; Rumage, Adam; Donini, Oreola; Haulenbeek, Andrea; Schaber, Christopher J.; Straube, Richard; Pullion, Christopher; Rook, Alain H.; Poligone, Brian 分享 收藏
Refining colorectal cancer classification and clinical stratification through a single-cell atlas (vol 23, 113, 2022) 通过单细胞图谱改进结直肠癌分类和临床分层 (第23卷，113，2022) Khaliq, Ateeq M.; Erdogan, Cihat; Kurt, Zeyneb; Turgut, Sultan Sevgi; Grunvald, Miles W.; Rand, Tim; Khare, Sonal; Borgia, Jefrey A.; Hayden, Dana M.; Pappas, Sam G.; Govekar, Henry R.; Kam, Audrey E.; Reiser, Jochen; Turaga, Kiran; Radovich, Milan; Zang, Yong; Qiu, Yingjie; Liu, Yunlong; Fishel, Melissa L.; Turk, Anita; Gupta, Vineet; Al-Sabti, Ram; Subramanian, Janakiraman; Kuzel, Timothy M.; Sadanandam, Anguraj; Waldron, Levi; Hussain, Arif; Saleem, Mohammad; El-Rayes, Bassel; Salahudeen, Ameen A.; Masood, Ashiq 分享 收藏
Refining colorectal cancer classification and clinical stratification through a single-cell atlas 通过单细胞图谱完善结直肠癌分类和临床分层 Khaliq, Ateeq M.; Erdogan, Cihat; Kurt, Zeyneb; Turgut, Sultan Sevgi; Grunvald, Miles W.; Rand, Tim; Khare, Sonal; Borgia, Jeffrey A.; Hayden, Dana M.; Pappas, Sam G.; Govekar, Henry R.; Kam, Audrey E.; Reiser, Jochen; Turaga, Kiran; Radovich, Milan; Zang, Yong; Qiu, Yingjie; Liu, Yunlong; Fishel, Melissa L.; Turk, Anita; Gupta, Vineet; Al-Sabti, Ram; Subramanian, Janakiraman; Kuzel, Timothy M.; Sadanandam, Anguraj; Waldron, Levi; Hussain, Arif; Saleem, Mohammad; El-Rayes, Bassel; Salahudeen, Ameen A.; Masood, Ashiq 分享 收藏
Gut Microbial Shifts Indicate Melanoma Presence and Bacterial Interactions in a Murine Model Rossi, Marco; Aspromonte, Salvatore M.; Kohlhapp, Frederick J.; Newman, Jenna H.; Lemenze, Alex; Pepe, Russell J.; DeFina, Samuel M.; Herzog, Nora L.; Donnelly, Robert; Kuzel, Timothy M.; Reiser, Jochen; Guevara-Patino, Jose A.; Zloza, Andrew 分享 收藏
Presence of CrkI-containing microvesicles in squamous cell carcinomas could have ramifications on tumor biology and cancer therapeutics Mohamed, Mohamed F.; Al-Khudari, Samer; Cassini-Vieira, Puebla; Erra, Amani; Bagabas, Reem; Houser, Thomas; Stenson, Kerstin; Bhayani, Mihir; Jelinek, Michael J.; Bishehsari, Faraz; Kuzel, Timothy M.; Shafikhani, Sasha H. 分享 收藏
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IL-10 Dysregulation Underlies Chemokine Insufficiency, Delayed Macrophage Response, and Impaired Healing in Diabetic Wounds Roy, Ruchi; Zayas, Janet; Mohamed, F. Mohamed; Aboonabi, Anahita; Delgado, Kaylee; Wallace, Jennillee; Bayat, Mohammad; Kuzel, Timothy M.; Reiser, Jochen; Shafikhani, Sasha H. 分享 收藏
Therapeutic evaluation of immunomodulators in reducing surgical wound infection Mahmud, Foyez; Roy, Ruchi; Mohamed, Mohamed F.; Aboonabi, Anahita; Moric, Mario; Ghoreishi, Kamran; Bayat, Mohammad; Kuzel, Timothy M.; Reiser, Jochen; Shafikhani, Sasha H. 分享 收藏
A Single-arm, Multicenter, Phase 2 Study of Lenvatinib Plus Everolimus in Patients with Advanced Non-Clear Cell Renal Cell Carcinoma Lenvatinib联合依维莫司在晚期非透明细胞肾细胞癌患者中的单臂，多中心，2期研究 Hutson, Thomas E.; Michaelson, M. Dror; Kuzel, Timothy M.; Agarwal, Neeraj; Molina, Ana M.; Hsieh, James J.; Vaishampayan, Ulka N.; Xie, Ran; Bapat, Urmi; Ye, Weifei; Jain, Rohit K.; Fishman, Mayer N. 分享 收藏
SEA-CD40 is a non-fucosylated anti-CD40 antibody with potent pharmacodynamic activity in preclinical models and patients with advanced solid tumors Neff-LaFord, Haley; Grilley-Olson, Juneko E.; Smith, David C.; Curti, Brendan; Goel, Sanjay; Kuzel, Timothy M.; Markovic, Svetomir N.; Rixe, Olivier; Bajor, David L.; Gajewski, Thomas F.; Gutierrez, Martin; Heath, Elisabeth I.; Thompson, John; Ansari, Sahar; Gardai, Shyra; Jacquemont, Celine; Schmitt, Michael; Coveler, Andrew L. 分享 收藏
Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer 肿瘤内注射季节性流感疫苗将免疫冷肿瘤转化为热肿瘤，并作为癌症的免疫疗法 Newman, Jenna H.; Chesson, C. Brent; Herzog, Nora L.; Bommareddy, Praveen K.; Aspromonte, Salvatore M.; Pepe, Russell; Estupinian, Ricardo; Aboelatta, Mones M.; Buddhadev, Stuti; Tarabichi, Saeed; Lee, Michael; Li, Shengguo; Medina, Daniel J.; Giurini, Eileena F.; Gupta, Kajal H.; Guevara-Aleman, Gabriel; Rossi, Marco; Nowicki, Christina; Abed, Abdulkareem; Goldufsky, Josef W.; Broucek, Joseph R.; Redondo, Raquel E.; Rotter, David; Jhawar, Sachin R.; Wang, Shang-Jui; Kohlhapp, Frederick J.; Kaufman, Howard L.; Thomas, Paul G.; Gupta, Vineet; Kuzel, Timothy M.; Reiser, Jochen; Paras, Joyce; Kane, Michael P.; Singer, Eric A.; Malhotra, Jyoti; Denzin, Lisa K.; Sant'Angelo, Derek B.; Rabson, Arnold B.; Lee, Leonard Y.; Lasfar, Ahmed; Langenfeld, John; Schenkel, Jason M.; Fidler, Mary Jo; Ruiz, Emily S.; Marzo, Amanda L.; Rudra, Jai S.; Silk, Ann W.; Zloza, Andrew 分享 收藏
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